Taste acuity of adult patients undergoing cancer treatment has been well investigated;however, studies of taste acuity after completion of cancer treatment are limited, particularly in children. This study aimed to as...Taste acuity of adult patients undergoing cancer treatment has been well investigated;however, studies of taste acuity after completion of cancer treatment are limited, particularly in children. This study aimed to assess taste acuity in pediatric cancer patients after treatment completion. Seventy-three patients who had completed cancer treatment (median age, 13 years;range, 7 - 18 years) and had not received any further treatment for at least 6 months were enrolled. Eighty-one healthy children (median age, 10 years;range, 8 - 19 years) served as controls. We determined the thresholds for four tastes (sweet, salty, sour, and bitter) using the filter-paper disc method. There was no significant difference in the thresholds of taste acuity for the four test solutions between the patient and control groups. The duration since treatment completion (<5 years vs. ≥5 years) had no significant impact on taste acuity for the four test solutions. The threshold for tasting salt was significantly higher in the group that had received chemotherapy + radiation and/or hematopoietic stem cell transplantation than that in the group that had received chemotherapy-only. Our results indicated that taste acuity after treatment completion in pediatric cancer patients was the same as that in healthy children. However, some treatment modalities were correlated with an impaired ability to taste salt. Gustatory test results should be considered while deciding nutritional support modalities after treatment completion in pediatric cancer patients.展开更多
为研究双峰孔隙结构对非饱和土力学特性的影响,以广西南宁和桂林2种典型双峰孔隙结构黏土为研究对象,分析了其在不同饱和度情况下的抗剪强度特性;辅以滤纸法及核磁共振(nuclear magnetic resonance,NMR)技术探究了2种土体在双峰孔隙结...为研究双峰孔隙结构对非饱和土力学特性的影响,以广西南宁和桂林2种典型双峰孔隙结构黏土为研究对象,分析了其在不同饱和度情况下的抗剪强度特性;辅以滤纸法及核磁共振(nuclear magnetic resonance,NMR)技术探究了2种土体在双峰孔隙结构情况下孔隙水分布状态对强度的影响机理。结果表明:饱和状态下,2种土体试样的T2分布曲线为双峰结构,且土样持水特性整体上均呈现双峰土水特征曲线;2种土体的应力-位移关系变化规律相似,抗剪强度与饱和度密切相关;在饱和度为40%前后土样黏聚力变化趋势发生改变,而内摩擦角则是在饱和度为80%时达到最小值。展开更多
红层软岩的崩解性引发显著的软岩风化破裂现象,经常导致坡体不稳定、岩石崩落等不良地质现象。为深入理解泥岩的水土特征曲线(soil and water characteristic curve,SWCC)和浸水崩解特征,以乐山红层泥岩为例,采用滤纸法、浸水法等试验...红层软岩的崩解性引发显著的软岩风化破裂现象,经常导致坡体不稳定、岩石崩落等不良地质现象。为深入理解泥岩的水土特征曲线(soil and water characteristic curve,SWCC)和浸水崩解特征,以乐山红层泥岩为例,采用滤纸法、浸水法等试验方法系统研究了泥岩的SWCC以及其在水中崩解的特征,构建了适合于该地区的SWCC模型,并讨论了浸水时间对泥岩崩解质量、颗粒级配的影响。结果表明:(1)泥岩的SWCC呈单峰曲线,随着含水率的减少,基质吸力增大。(2)通过与4种典型率定曲线的拟合比较,基质吸力拟合结果表现出良好的相关性(R^(2)≥92%),其中Fredlund&Xing模型能够更准确地反映该地区泥岩的SWCC(R^(2)=96%)。(3)浸水试验表明,0~6 h为快速崩解期,6~12 h为慢速崩解期,12 h后为长期崩解期。干湿交替浸水可以加速泥岩在亲水初期的崩解速率,但在最终崩解量方面与持续浸水基本一致。(4)浸水崩解后,颗粒粒径变化主要集中在2~20 mm范围内,级配曲线D_(60),D_(30),D_(10)和Cu值随着浸水时间的增大而减少,表明泥岩颗粒粒径随时间逐渐减小。(5)该泥岩耐崩解指数拟合公式为y=1.17e-0.22x,拟合度良好(R^(2)≥99%),根据I_(d2)=0.76判断该地区泥岩崩解性为弱~中等崩解性。该成果可为该地区泥岩的水土特性和崩解特性提供重要的定量数据支持,以及为该地区工程建设提供理论依据。展开更多
This study aimed to investigate the toxicity of rare earth ion yttrium under the stress of leaching agent ammonium sulfate （NH4）2SO4. [Method] By using earthworms as indicator organisms of environmental pol ution, a...This study aimed to investigate the toxicity of rare earth ion yttrium under the stress of leaching agent ammonium sulfate （NH4）2SO4. [Method] By using earthworms as indicator organisms of environmental pol ution, acute toxic ef-fects of rare earth yttrium on earthworms under the stress of ammonium sulfate were investigated with filter paper contact method. [Result] Under single stress of rare earth yttrium, the semi-lethal concentration after 48 and 24 h was LC50=213.41 mg/L and LC50=322.63 mg/L, respectively. ② Under single stress of ammonium sul-fate, the semi-lethal concentration after 48 h and 24 h was LC50=13.89 g/L and LC50=15.05 g/L, respectively. ③ In combined treatment of low concentration （10 g/L） of ammonium sulfate and different doses of rare earth yttrium, the semi-lethal con-centration after 48 and 24 h was LC50=198.65 g/L and LC50=399.85 g/L, respective-ly; in combined treatment of middle concentration （14 g/L） of ammonium sulfate and different doses of rare earth yttrium, the semi-lethal concentration after 48 and 24 h was LC50=167.3 mg/L and LC50=256.73 mg/L, respectively; in combined treatment of high concentration （20 g/L） of ammonium sulfate and different doses of rare earth yttrium, the semi-lethal concentration after 48 h and 24 h was LC50=31.03 mg/L and LC50=127.65 mg/L, respectively. [Conclusion] Low concentration of ammonium sulfate could reduce the toxicity of rare earth yttrium to earthworms and produce certain antagonism against rare earth yttrium; middle concentration ammonium sulfate in-creased the toxicity of rare earth yttrium to earthworms and produced relatively sig-nificant synergistic effects; high concentration ammonium sulfate significantly in-creased the toxicity of rare earth yttrium to earthworms. Compared with ammonium sulfate, dead earthworms exposed to rare earth yttrium were more easily fractured, and living earthworms showed insensitive response to acupuncture.展开更多
文摘Taste acuity of adult patients undergoing cancer treatment has been well investigated;however, studies of taste acuity after completion of cancer treatment are limited, particularly in children. This study aimed to assess taste acuity in pediatric cancer patients after treatment completion. Seventy-three patients who had completed cancer treatment (median age, 13 years;range, 7 - 18 years) and had not received any further treatment for at least 6 months were enrolled. Eighty-one healthy children (median age, 10 years;range, 8 - 19 years) served as controls. We determined the thresholds for four tastes (sweet, salty, sour, and bitter) using the filter-paper disc method. There was no significant difference in the thresholds of taste acuity for the four test solutions between the patient and control groups. The duration since treatment completion (<5 years vs. ≥5 years) had no significant impact on taste acuity for the four test solutions. The threshold for tasting salt was significantly higher in the group that had received chemotherapy + radiation and/or hematopoietic stem cell transplantation than that in the group that had received chemotherapy-only. Our results indicated that taste acuity after treatment completion in pediatric cancer patients was the same as that in healthy children. However, some treatment modalities were correlated with an impaired ability to taste salt. Gustatory test results should be considered while deciding nutritional support modalities after treatment completion in pediatric cancer patients.
文摘为研究双峰孔隙结构对非饱和土力学特性的影响,以广西南宁和桂林2种典型双峰孔隙结构黏土为研究对象,分析了其在不同饱和度情况下的抗剪强度特性;辅以滤纸法及核磁共振(nuclear magnetic resonance,NMR)技术探究了2种土体在双峰孔隙结构情况下孔隙水分布状态对强度的影响机理。结果表明:饱和状态下,2种土体试样的T2分布曲线为双峰结构,且土样持水特性整体上均呈现双峰土水特征曲线;2种土体的应力-位移关系变化规律相似,抗剪强度与饱和度密切相关;在饱和度为40%前后土样黏聚力变化趋势发生改变,而内摩擦角则是在饱和度为80%时达到最小值。
文摘红层软岩的崩解性引发显著的软岩风化破裂现象,经常导致坡体不稳定、岩石崩落等不良地质现象。为深入理解泥岩的水土特征曲线(soil and water characteristic curve,SWCC)和浸水崩解特征,以乐山红层泥岩为例,采用滤纸法、浸水法等试验方法系统研究了泥岩的SWCC以及其在水中崩解的特征,构建了适合于该地区的SWCC模型,并讨论了浸水时间对泥岩崩解质量、颗粒级配的影响。结果表明:(1)泥岩的SWCC呈单峰曲线,随着含水率的减少,基质吸力增大。(2)通过与4种典型率定曲线的拟合比较,基质吸力拟合结果表现出良好的相关性(R^(2)≥92%),其中Fredlund&Xing模型能够更准确地反映该地区泥岩的SWCC(R^(2)=96%)。(3)浸水试验表明,0~6 h为快速崩解期,6~12 h为慢速崩解期,12 h后为长期崩解期。干湿交替浸水可以加速泥岩在亲水初期的崩解速率,但在最终崩解量方面与持续浸水基本一致。(4)浸水崩解后,颗粒粒径变化主要集中在2~20 mm范围内,级配曲线D_(60),D_(30),D_(10)和Cu值随着浸水时间的增大而减少,表明泥岩颗粒粒径随时间逐渐减小。(5)该泥岩耐崩解指数拟合公式为y=1.17e-0.22x,拟合度良好(R^(2)≥99%),根据I_(d2)=0.76判断该地区泥岩崩解性为弱~中等崩解性。该成果可为该地区泥岩的水土特性和崩解特性提供重要的定量数据支持,以及为该地区工程建设提供理论依据。
基金Supported by National Natural Science Foundation of China(Grant No.21067003,51364015)National High-Tech Research and Development Program of China(GrantNo.2012BAC11B07)+1 种基金Natural Science Foundation of Jiangxi Province(Grant No.20114BAB203024)Science and Technology Project of the Education Department ofJiangxi Province~~
文摘This study aimed to investigate the toxicity of rare earth ion yttrium under the stress of leaching agent ammonium sulfate （NH4）2SO4. [Method] By using earthworms as indicator organisms of environmental pol ution, acute toxic ef-fects of rare earth yttrium on earthworms under the stress of ammonium sulfate were investigated with filter paper contact method. [Result] Under single stress of rare earth yttrium, the semi-lethal concentration after 48 and 24 h was LC50=213.41 mg/L and LC50=322.63 mg/L, respectively. ② Under single stress of ammonium sul-fate, the semi-lethal concentration after 48 h and 24 h was LC50=13.89 g/L and LC50=15.05 g/L, respectively. ③ In combined treatment of low concentration （10 g/L） of ammonium sulfate and different doses of rare earth yttrium, the semi-lethal con-centration after 48 and 24 h was LC50=198.65 g/L and LC50=399.85 g/L, respective-ly; in combined treatment of middle concentration （14 g/L） of ammonium sulfate and different doses of rare earth yttrium, the semi-lethal concentration after 48 and 24 h was LC50=167.3 mg/L and LC50=256.73 mg/L, respectively; in combined treatment of high concentration （20 g/L） of ammonium sulfate and different doses of rare earth yttrium, the semi-lethal concentration after 48 h and 24 h was LC50=31.03 mg/L and LC50=127.65 mg/L, respectively. [Conclusion] Low concentration of ammonium sulfate could reduce the toxicity of rare earth yttrium to earthworms and produce certain antagonism against rare earth yttrium; middle concentration ammonium sulfate in-creased the toxicity of rare earth yttrium to earthworms and produced relatively sig-nificant synergistic effects; high concentration ammonium sulfate significantly in-creased the toxicity of rare earth yttrium to earthworms. Compared with ammonium sulfate, dead earthworms exposed to rare earth yttrium were more easily fractured, and living earthworms showed insensitive response to acupuncture.
