This study used the radioimmunoassay method to observe 11 cases of prolapsed interver-tebral disc and to detect the change of cAMP and cGMP in the cerebrospinal fluid before and after fingerpressing manipulation in ac...This study used the radioimmunoassay method to observe 11 cases of prolapsed interver-tebral disc and to detect the change of cAMP and cGMP in the cerebrospinal fluid before and after fingerpressing manipulation in acupuncture point Weizhong (UB 40) and Chengshan (UB 57) in order to discussthe mechanism of analgesia of finger pressing manipulation. The results show the pain was relieved afterfinger pressing manipulation. cGMP of the cerebrospinal fluid increased from 0. 51±0. 19 to 0. 63±0. 13pm/ml, in average 32% higher than before the treatment (P<0. 05) . Since cAMP/cGMP decreased from30.52±26. 42 to 23.20 ± 16.91, this shows the analgesic mechanism of finger pressing manipulation mightbe due to the fact that the therapy excited the selectively endogenous analgesic system, caused the in-creased release of endorphin, and was accompanied by regulation ot cAMP and cGMP.展开更多
文摘This study used the radioimmunoassay method to observe 11 cases of prolapsed interver-tebral disc and to detect the change of cAMP and cGMP in the cerebrospinal fluid before and after fingerpressing manipulation in acupuncture point Weizhong (UB 40) and Chengshan (UB 57) in order to discussthe mechanism of analgesia of finger pressing manipulation. The results show the pain was relieved afterfinger pressing manipulation. cGMP of the cerebrospinal fluid increased from 0. 51±0. 19 to 0. 63±0. 13pm/ml, in average 32% higher than before the treatment (P<0. 05) . Since cAMP/cGMP decreased from30.52±26. 42 to 23.20 ± 16.91, this shows the analgesic mechanism of finger pressing manipulation mightbe due to the fact that the therapy excited the selectively endogenous analgesic system, caused the in-creased release of endorphin, and was accompanied by regulation ot cAMP and cGMP.
