Clinical validation of the early embryo viability assessment system: Analysis for the blastocyst morphology and pregnancy outcomes

Objective:To determine the relationship between the early embryo viability assessment(EEVA)and blastocyst morphological parameters and pregnancy outcomes.Methods:This retrospective cohort study was conducted on 291 intracytoplasmic sperm injection cycles including 2522 embryos with indications of prolonging embryo culture to the blastocyst stage in the Genea embryo review incubator,and 511 single vitrified-warmed blastocyst transfer cycles from January 2020 to June 2023.The EEVA system produced an EEVA score from E1(best)to E5(worse)for the potential of blastocyst formation.Blastocyst morphology was evaluated.The association between the EEVA score and each type of blastocyst morphology,implantation rate,clinical pregnancy,and ongoing pregnancy were assessed using generalized estimating equations.Results:The inner cell mass A(ICM A),trophectoderm A(TE A),blastocoele expansion degree of 3,4,5,6,7 rates were higher with lower the EEVA score.The adjusted odd ratio(aOR)(E5 vs E1)was 0.3 for ICM A,0.174 for TE A and 0.210 for BL3,4,5,6,7(all P<0.001),suggesting a significant association between lower EEVA scores and improved embryo quality.The implantation,clinical pregnancy,and ongoing pregnancy rate were also higher with lower the EEVA score.The aOR of E5 vs E1 was 0.245 for implantation,0.185 for clinical pregnancy and 0.200 for ongoing pregnancy rate(P<0.001).Conclusions:There were associations between blastocyst morphology,pregnancy outcome and EEVA scores.The good blastocyst morphology and pregnancy outcomes are higher with lower the EEVA score.

Research on the Assessment System of Computational Mechanics Courses Based on the TOPSIS Entropy Weight Model

This paper takes the assessment and evaluation of computational mechanics course as the background,and constructs a diversified course evaluation system that is student-centered and integrates both quantitative and qualitative evaluation methods.The system not only pays attention to students’practical operation and theoretical knowledge mastery but also puts special emphasis on the cultivation of students’innovative abilities.In order to realize a comprehensive and objective evaluation,the assessment and evaluation method of the entropy weight model combining TOPSIS(Technique for Order Preference by Similarity to Ideal Solution)multi-attribute decision analysis and entropy weight theory is adopted,and its validity and practicability are verified through example analysis.This method can not only comprehensively and objectively evaluate students’learning outcomes,but also provide a scientific decision-making basis for curriculum teaching reform.The implementation of this diversified course evaluation system can better reflect the comprehensive ability of students and promote the continuous improvement of teaching quality.

Research on the Reform of the Process-Tracking Ideological and Political Assessment System in Applied Universities:Taking the Personal Finance Course as an Example

Using the Xi’an Mingde Institute of Technology students as the teaching object and the Personal Finance course as an example,we explore the reform of the ideological and political assessment system of process-tracking courses in applied universities.The article analyzes the feasibility of applying the curriculum ideological and political assessment system in college courses and compares the traditional assessment system.It also proposes that applying curriculum ideological and political assessment to the college curriculum assessment system will help improve students’understanding of the“value guidance”in curriculum ideological and political education and enhance the teaching effect.

Dilemmas and Optimization of Third-Party Assessment System in Chinese Fair Competition Review

The current predominant self-review mechanism by policy-making bodies suffers from deficiencies such as insufficient motivations, limited review capabilities, and weak external supervision. Third-party assessment, characterized by independence and specialization, is designed to mitigate these shortcomings. However, the implementation of third-party assessment faces challenges too. This paper intends to improve the third-party assessment system and to realize the legislative purpose of the system. Based on social research, discussions and exchanges with relevant parties, and the existing research results, this paper analyzes the challenges and possible optimization measures for the third-party assessment. The challenges include repulsion from policy-making bodies, insufficient independence of assessment bodies, disparity of assessment quality, and limited application of assessment outcomes. Possible optimization measures include promoting fair competition culture, increasing the acceptance of third-party assessment from policy-making bodies, enhancing the quality of third-party assessment, clarifying the relationship between policy-making bodies and assessment bodies, ensuring the independence of third-party assessments, and promoting the application of assessment results.

Monitoring and Assessment System of Agricultural Drought Based on GIS Technology

[Objective] The research aimed to simplify the operating process of agricultural drought monitoring and assessment product,and improve fine level of monitoring and assessment map.[Method] By comprehensively using GIS and mathematics,meteorology,management science,computer science,the monitoring and assessment of drought were as the core,the monitoring and assessment system of agricultural drought based on GIS technology was studied.[Result] The drought in Guangxi on November 4,2006 was monitored by using the system,and the actual situation was used to test.The result proved that the good monitoring effect was obtained.[Conclusion] The monitoring and assessment system of agricultural drought based on GIS realized the organic combination of GIS and professional monitoring,assessment model.The flexible HCI interface and visualization expression were provided.The monitoring and assessment function of agricultural drought was realized.It had the good practicality and advancement.

Image analysis and machine learning-based malaria assessment system

Malaria is an important and worldwide fatal disease that has been widely reported by the World Health Organization(WHO),and it has about 219 million cases worldwide,with 435,000 of those mortal.The common malaria diagnosis approach is heavily reliant on highly trained experts,who use a microscope to examine the samples.Therefore,there is a need to create an automated solution for the diagnosis of malaria.One of the main objectives of this work is to create a design tool that could be used to diagnose malaria from the image of a blood sample.In this paper,we firstly developed a graphical user interface that could be used to help segment red blood cells and infected cells and allow the users to analyze the blood samples.Secondly,a Feed-forward Neural Network(FNN)is designed to classify the cells into two classes.The achieved results show that the proposed techniques can be used to detect malaria,as it has achieved 92%accuracy with a database that contains 27,560 benchmark images.

Research on Architecture of Risk Assessment System Based on Block Chain

The risk assessment system has been applied to the information security,energy,medical and other industries.Through the risk assessment system,it is possible to quantify the possibility of the impact or loss caused by an event before or after an event,thereby avoiding the risk or reducing the loss.However,the existing risk assessment system architecture is mostly a centralized architecture,which could lead to problems such as data leakage,tampering,and central cheating.Combined with the technology of block chain,which has the characteristics of decentralization,security and credibility,collective maintenance,and untamperability.This paper proposes a new block chainbased risk assessment system architecture and a consensus mechanism algorithm based on DPOS improvement.This architecture uses an improved consensus mechanism to achieve a safe and efficient risk assessment solving the problem of data tampering in the risk assessment process,avoiding data leakage caused by improper data storage.A convenient,safe and fast risk assessment is achieved in conjunction with the improved consensus mechanism.In addition,by comparing existing risk assessment architecture,the advantages and impacts of the new block chain-based risk assessment system architecture are analyzed.

Tri-Intersectional Model of Leadership by Values:A Fuzzy Multi-Criteria Decision Making Open Technology Assessment System

Purpose-Nowadays successful organizations need to be masters at leadership by values to play in a constantly changing and transforming environment.But how can leaders and organizations effectively convene strategic and culture development based on values?This paper presents the Tri-Intersectional Model of Leadership by Values(TMLV)in which leaders and organizations can integrate a sustainable strategy,as well as a culture and value-based management system that simultaneously leverages human,financial,and social resources.With its three essential axes of values(economic-pragmatic,emotional-development,and ethical-social)at their intersection points,it allows leaders to focus on the strategy linkages:innovation-intersection between the economic-pragmatic values axis and the emotional-development values axis-allows them to develop sustainable innovations;survival-intersection between the economic-pragmatic values axis and the ethical-social values axis-enhances their organization’s survival;finally,sensibility-intersection between the economic-pragmatic values axis and the ethical-social values axis-makes them more humane and more socially-responsible.The application of the TMLV,using the Fuzzy Multi-Criteria Decision Making Open Technology Assessment System,can be a great inspiration for stimulating and working with values in organizations,as well as allowing leaders to develop a values-based,high-involvement,and performance-oriented culture.Methodology/Approach-This research considers empirical data analysis of the 37 case studies of the EU-InnovatE project(http//www.euinnovate.com)-a pioneering initiative to align innovation values to integrate the end user into the process of innovation and entrepreneurship related to a sustainable lifestyle and the green economy in Europe-using a fuzzy multiple-criteria decision making method and open technologies system,such as server-side PHP language,MariaDB Database,fork of MYSQL Database Management System,and JavaScript libraries to perform operation directly on the user’s browser.Findings-The application of the TMLV model,considering empirical analysis of the extracted values from the case studies,using the Fuzzy Multi-Criteria Decision Making Open Technology Assessment System,can be a great inspiration for stimulating and working with values in João organizations,as well as allowing leaders to develop suitable strategies and interventions for shaping a sustainable high-performance culture.Research implications-This research can be a starting point for further research to assess the effectiveness of the leadership model based on a decision-making open technology system in any given organization,as well as to invite researchers who have positive passion about working with values to participate in the improvement of this tool.Originality/value-The Tri-Intersectional Model of Leadership by Values using the Fuzzy Multi-Criteria Decision Making Open Technology Assessment System is presented as an evolution in leadership models that may be used to fuel innovation,survival,and a sensibility strategic focus that is necessary to optimize human and organizational performance and deliver effective solutions to the massive array of human,financial,and social problems we face today.

Efficacy of Simple Assessment System of Oocyte Maturity in IVF-ET Cycles

Objective To establish and evaluate the efficacy of the simple assessment system of oocyte maturity. Methods A total of 251 couples were enrolled in this study and female patients were divided into two groups. In group Ⅰ, oocytes were inseminated at 6 h after ovum pick-up. In group Ⅱ, oocyte maturity was rapidly categorized by simple assessment system. Mature oocytes were inseminated at 3-4 h after ovum pick-up when oocyte-corona complexes （OCC） exhibited clear thick ring-like halo （RLH） and expanded cumulus cells （CC） or 5-6 h when OCC exhibited RLH and a few clumped and/or dark CC, respectively. Intermediate oocytes were inseminated at 7-8 h when RLH was not found around the OCC and CC were compacted and clumped and/or dark. Results Normal fertilization rate was higher in group Ⅱ （76.5%） than that in group Ⅰ （58.0%） （P〈0.001）. However, abnormal fertilization rate was higher in group Ⅰ（11.3%） than that in group 11 （3.6%） （P〈0.001）. The cleavage （82.6% vs 90.0%）, chemical pregnancy （4. 8% vs 3.9%）, twin pregnancy （6. 7% vs 3.9%） and implantation rate （8.4% vs 10.6%） had no statistically differences between group I and Ⅱ. Rate of clinical and singleton pregnancy was higher in groupⅡ （35.3% and 31.4%） than those in group Ⅰ （24.8% and 18.2%） （P〈0.05）. Conclusion This simple assessment system is useful and effective for evaluation and categorization of the oocyte maturity with better reproductive outcomes.

Statistical Assessment System of Thunder and Lightning Disaster in Yantai City

Starting from lightning disaster information and using computer technology, lightning disaster information is arranged and classified, thereby realizing automatic management of lightning disaster information.

Feasibility and reliability of the revised Edmonton Symptom Assessment System(ESAS-r)in Egyptian patients with advanced cancer:A single institutional experience

Objective This study aims to test the acceptance, feasibility, and usefulness of the Arabic version of the revised Edmonton Symptom AssesSment System （ESAS-r） among Egyptian patients with advanced cancer and to compare the rates of symptoms documented by patients and physicians. Methods Between August 2014 and February 2015, a total of 140 patients at Ain Shams University Hospitals in Cairo, Egypt received the Arabic version of the ESAS-r. For each patient, the ESAS-r was completed twice, first by the treating physician （as part of the basic assessment） and a second time by the patient, with a maximum of 2 hours between the two assessments. An additional survey was included to assess patients＇ acceptance of the survey and their preferences. Results Out of 140 enrolled patients in the study, 11 patients refused to complete the questionnaire, and 10 patients were excluded due to incomplete records in their medical records. Complete data was retrieved for 119 patients who were included for further analyses. The 78 （65%） patients declared that the test was clear and easy to complete. They were able to answer the test without help. Collectively, tiredness and sense of well-being were the most commonly encountered symptoms in ratings obtained by both patients and physicians. Tiredness was the only symptom showing a significant difference between the two rating methods, patient-rated scores being higher （P = 0.032）. Cronbach＇s alpha showed that both tests com- pleted by the physician and the patients were internally consistent： the physician-rated test had a coefficient of 0.877, and the patient-rated test had a coefficient of 0.863. All ESAS scores had good internal consis- tency, with a Cmnbach＇s alpha coefficient of 0.88. The internal consistency remained high after removal of individual symptom scores, with Cronbach＇s alpha coefficients ranging from 0.823 to 0.902, indicating that no individual question had undue influence on the total ESAS score. Conclusion The ESAS-r was easily understood by and applicable to patients. There was no significant discrepancy in the rates of symptoms reported by the patients and physicians, apart from tiredness. Based on this, the test could be applied on a larger scale with in-home patients. This test can be cost-effective and can decrease the number of hospital visits among advanced cancer patients in need of supportive treat- ment rather than active cancer therapy.

Benefit to Chinese High School Students' Academic Learning Outcome and Evaluation by Comparing Two Different Assessment Systems

More and more researchers are becoming involved through a variety of actions and programs, which divides assessment into different branches(such as formative, summative, normative assessment, etc). In the present paper, I will try to emphasis that collaborative assessment is positive to high school students' learning outcome, and cooperative and competitive assessment should be mixture implemented in Chinese education process rather than only using competitive assessment to evaluate students' achievement. I hope that Chinese students and teachers could teach or test in the less pressure by reforming the educational evaluation system.

The progress of research in medical-image assessment system of melasma

Melasma, a kind of damaging disease, is commonly found in women during reproductive age. It causes great harm to patient＇s confidence and, has an effect on social contact as well. Melasma has been cured effectively by modern medicine and traditional Chinese medicine so far, in contrast, the treatment analysis system is far from flawless. Our research team is going to cooperate with Beijing University of Aeronautics and Astronautics and develop a computer-vision treatment analysis system for facial dermatosis based on present technology. It＇s supposed to provide clinical doctors with objective standards for melasma and other facial dermatosis.

Achieve Research Excellence through Improvement of Science Assessment System

With the support of the Consultation and Evaluation Committee of the Academic Divisions of the Chinese Academy of Sciences(CAS),a task force headed by CAS Member FANG Rongxiang recently conducted a project entitled Science Value Assessment in an Increasingly Globalized World.Based on the study,the researchers presented a report on the improvement of China’s science assessment system.The following paragraphs present the major ideas of this report.

A risk assessment system for alien plant bio-invasion in Xiamen,China

Bio-invasion has caused serious ecosystem damage and enormous economic losses in China,and it has been the greatest factor to island bio-diversity reduction.Xiamen,as an important seaport with a relatively high conservation value,is particularly vulnerable to bio-invasion for its typical island ecosystem as well as frequent human-made disturbance.As a result of field surveys,literature review, and consultation with experts,a list of 67 alien plants identified as major invaders(12 species)and emerging invade...

Rapid building damage assessment system using mobile phone technology

One common scenario during disasters such as earthquakes is that the activity of damage field reconnaissance on site is not well-coordinated. For example in Italy the damage assessment of structures after an earthquake is managed from the Italian Emergency Authority, using printed forms （AeDES） which are filled by experts on site generating a lot of confusion in filling and transferring the forms to the Disaster Management Operative Center. Because of this, the paper explores the viability of using mobile communication technologies （smart phones） and the Web to develop response systems that would aid communities after a major disaster, providing channels for allowing residents and responders ofuploading and distributing information, related to structural damages coordinating the damage field reconnaissance. A mobile application that can be run by residents on smart phones has been developed, to give an initial damage evaluation of the area, which is going to be very useful when resources （e.g. the number of experts is limited）. The mobile application has been tested for the first time during 2012 Emilia earthquake to enhance the emergency response, showing the efficiency of the proposed method in statistical terms comparing the proposed procedure with the standard procedure.

Quantitative hazard assessment system(Has-Q) for open pit mine slopes

Rock slope hazard assessment is an important part of risk analysis for open pit mines.The main parameters that can lead to rock slope failures are the parameters traditionally used in geomechanical classifications,the slope geometrical parameters and external factors like rainfall and blasting.This paper presents a methodology for a hazard assessment system for open pit mine slopes based on 88 cases collated around the world using principal components analysis,discriminant analysis and confidence ellipses.The historical cases used in this study included copper,gold,iron,diamond,lead and zinc,platinum and claystone mines.The variables used in the assessment methodology are uniaxial compressive strength of intact rock;spacing,persistence,opening,roughness,infilling and orientation of the main discontinuity set;weathering of the rock mass;groundwater;blasting method;and height and inclination of the pit.While principal component analysis was used to quantify the data,the discriminant analysis was used to establish a rule to classify new slopes about its stability condition.To provide a practical hazard assessment system,confidence ellipses were used to propose a hazard graph and generate the HAS-Q.The discriminant rule developed in this research has a high discrimination capacity with an error rate of 11.36%.

Developing a risk assessment system for gas tunnel disasters in China

Gas disasters always restrict the tunnel constructions in mountain area, which becomes a major geological barrier against the development of underground engineering. China is rich in coal resources and has a large amount of gas with a wide range of distribution. However, China experienced not only adverse effects on coal mining but also gas disasters in underground engineering construction, such as tunnels and chambers. With the increased number of tunnels passing through coal-bearing strata, the incidence of gas accidents is also rising. Therefore, the significance of preventing and mitigating gas disasters should be emphasized, and an effective risk assessment method for gas disasters should be established. On the basis of research on over 100 gas tunnels in China, a relatively ideal gas disaster risk assessment method and system for tunnels are established through the following measures. Firstly, geo-environmental conditions and gas situations were analyzed during construction. Secondly, qualitative analysis was combined with quantitative analysis. Finally, the influencing factors of gas disasters, including geological conditions, gas,and human factors, were investigated. The gas tunnel risk assessment system includes three levels:(1) the grading assessment of a gas tunnel during the planning stage,(2) the risk assessment of gas tunnel construction during the design and construction stages,(3) the gas tunnel outburst risk assessment during the coal uncovering stage. This system was applied to the dynamic assessment of gas disaster during the construction of the Zipingpu tunnel of Dujiangyan–Wenchuan Highway(in Sichuan, Southwest China). The assessment results were consistent with the actual excavation, which verified the rationality and feasibility of the system. The developed system was believed to be back-up and applied for risk assessment of gas disaster in the underground engineering construction.

A Study of an Intelligent Battlefield Damage Assessment System Based on a Multi-agent System

Battlefield damage assessment is the key to Battlefield Damage Assessment and Repair （ BDAR ） . We present an Intelligent Battlefield Damage Assessment System （IBDAS） based on multiagent system technology. We first establish the system framework, and then study the interior structure and workflow of a problem allocation agent. The result shows that, there are many advantages to resolve the problem of battlefield damage assessment by applying multi-agent system technology, and it will bring significant military benefit.

Creation of an assessment system for measuringthe bitterness of azithromycin-containing reversemicelles

We aimed to develop a novel method for assessing the bitterness of azithromycin-containing reverse micelles(AM-containing RMs). Azithromycin-containing reverse mi-celles were prepared by processing Lipoid E80 and medium chain triglycerides via a freeze-drying method. The bitterness threshold of azithromycin was determined by human tastetest, and an equation was derived to correlate the azithromycin concentrations and bitter-ness scores of standard solutions. Simulated salivary fluids and sampling times were fixedbased on the drug release profile of AM-containing RMs, with Zithromax ?(a commercialformulation of azithromycin) used as the control. The drug release concentrations fromstimulated salivary fluids were then used to assess the bitterness of AM-containing RMsand Zithromax ?. Afterward, the oral bioavailability of both formulations was evaluated byin vivo experiments in male Wistar rats. The results showed that the bitterness thresh-old of azithromycin standard solutions was between 25.3 μg/ml and 30.4 μg/ml. There-after, we calculated that the bitterness scores and the drug release concentrations of theazithromycin-containing reverse micelle formulation were similar to those of Zithromax ?ateach time point after 10 min of dispersal in simulated salivary fluid. In addition, the AUC 0-tafter oral administration of AM-containing RMs was 1.75-fold( P < 0.05) higher than that ofZithromax ?. In conclusions, a system for assessing bitterness was developed using an in vitrodrug release evaluation method and a human taste test panel. We found that the bitterness of azithromycin was successfully masked by reverse micelles, which also improved the oral bioavailability of azithromycin compared to that of Zithromax ?.