Methodological quality(risk of bias)assessment is an important step before study initiation usage.Therefore,accurately judging study type is the first priority,and the choosing proper tool is also important.In this re...Methodological quality(risk of bias)assessment is an important step before study initiation usage.Therefore,accurately judging study type is the first priority,and the choosing proper tool is also important.In this review,we introduced methodological quality assessment tools for randomized controlled trial(including individual and cluster),animal study,non-randomized interventional studies(including follow-up study,controlled before-and-after study,before-after/pre-post study,uncontrolled longitudinal study,interrupted time series study),cohort study,case-control study,cross-sectional study(including analytical and descriptive),observational case series and case reports,comparative effectiveness research,diagnostic study,health economic evaluation,prediction study(including predictor finding study,prediction model impact study,prognostic prediction model study),qualitative study,outcome measurement instruments(including patient-reported outcome measure development,content validity,structural validity,internal consistency,cross-cultural validity/measurement invariance,reliability,measurement error,criterion validity,hypotheses testing for construct validity,and responsiveness),systematic review and meta-analysis,and clinical practice guideline.The readers of our review can distinguish the types of medical studies and choose appropriate tools.In one word,comprehensively mastering relevant knowledge and implementing more practices are basic requirements for correctly assessing the methodological quality.展开更多
目的：调查汶川地震后，极重灾区社区居民创伤后应激障碍发生率及影响因素，为进一步开展灾后心理卫生服务提供依据。方法：采用整群随机抽样的方法，从安县京安小区、什邡红白镇两个临时安置点社区居民2685人中，随机抽取820名社区居...目的：调查汶川地震后，极重灾区社区居民创伤后应激障碍发生率及影响因素，为进一步开展灾后心理卫生服务提供依据。方法：采用整群随机抽样的方法，从安县京安小区、什邡红白镇两个临时安置点社区居民2685人中，随机抽取820名社区居民登记人口学背景、受灾状况，并使用PTSD检查量表平民版（PTSD Checklist—Civilian Version，PCL—C）和领悟社会支持量表（Perceived Social Support Scale，PSSS）进行评估，依据DSM-Ⅳ中PTSD的诊断标准确诊PTSD患者。结果：在完成的820份调查评估资料中，785份PCL—C和PSSS问卷有效。男女比例为1：1．41；平均年龄（43±18）岁；26．0％患有躯体疾病，28．4％有地震前饮酒习惯，23．6％有震后饮酒行为。不同年龄居民PSSS总分及2因子分差异均无统计学意义（P〉0．05）。PTSD的临床检出率为12．4％（97／785），女性PTSD发生率高于男性（15．3％vs．8．3％，P=0．003），地震中有曾被掩埋经历者PTSD发生率高于无被掩埋经历者（26．3％vs．11．6％，P=0．018），有丧亲者的FFSD发生率高于无丧亲者（18．7％vs．11．1％，P=0．015）。以PTSD诊断是否成立为因变量，一般资料为自变量进行Logistic回归分析显示：女性（OR=2．070，95％CI：1．274—3．365）、有曾被掩埋经历者（OR=2．806，95％CI：1．249～6．306）、亲人丧失（OR=1．537，95％CI：1．087—2．173）及PSSS评分偏低（OR=0．960，95％CI：0．941～0．979）是PTSD发生的危险因素。结论：在灾后社区重建过程中，临时安置点社区居民存在较高的创伤后应激障碍的发生率，女性、有曾被掩埋经历、亲人丧失及个人感受到的社会支持偏低是PTSD发生的危险因素。展开更多
基金supported(in part)by the Entrusted Project of National commission on health and health of China(No.2019099)the National Key Research and Development Plan of China(2016YFC0106300)the Nature Science Foundation of Hubei Province(2019FFB03902)。
文摘Methodological quality(risk of bias)assessment is an important step before study initiation usage.Therefore,accurately judging study type is the first priority,and the choosing proper tool is also important.In this review,we introduced methodological quality assessment tools for randomized controlled trial(including individual and cluster),animal study,non-randomized interventional studies(including follow-up study,controlled before-and-after study,before-after/pre-post study,uncontrolled longitudinal study,interrupted time series study),cohort study,case-control study,cross-sectional study(including analytical and descriptive),observational case series and case reports,comparative effectiveness research,diagnostic study,health economic evaluation,prediction study(including predictor finding study,prediction model impact study,prognostic prediction model study),qualitative study,outcome measurement instruments(including patient-reported outcome measure development,content validity,structural validity,internal consistency,cross-cultural validity/measurement invariance,reliability,measurement error,criterion validity,hypotheses testing for construct validity,and responsiveness),systematic review and meta-analysis,and clinical practice guideline.The readers of our review can distinguish the types of medical studies and choose appropriate tools.In one word,comprehensively mastering relevant knowledge and implementing more practices are basic requirements for correctly assessing the methodological quality.
文摘目的：调查汶川地震后，极重灾区社区居民创伤后应激障碍发生率及影响因素，为进一步开展灾后心理卫生服务提供依据。方法：采用整群随机抽样的方法，从安县京安小区、什邡红白镇两个临时安置点社区居民2685人中，随机抽取820名社区居民登记人口学背景、受灾状况，并使用PTSD检查量表平民版（PTSD Checklist—Civilian Version，PCL—C）和领悟社会支持量表（Perceived Social Support Scale，PSSS）进行评估，依据DSM-Ⅳ中PTSD的诊断标准确诊PTSD患者。结果：在完成的820份调查评估资料中，785份PCL—C和PSSS问卷有效。男女比例为1：1．41；平均年龄（43±18）岁；26．0％患有躯体疾病，28．4％有地震前饮酒习惯，23．6％有震后饮酒行为。不同年龄居民PSSS总分及2因子分差异均无统计学意义（P〉0．05）。PTSD的临床检出率为12．4％（97／785），女性PTSD发生率高于男性（15．3％vs．8．3％，P=0．003），地震中有曾被掩埋经历者PTSD发生率高于无被掩埋经历者（26．3％vs．11．6％，P=0．018），有丧亲者的FFSD发生率高于无丧亲者（18．7％vs．11．1％，P=0．015）。以PTSD诊断是否成立为因变量，一般资料为自变量进行Logistic回归分析显示：女性（OR=2．070，95％CI：1．274—3．365）、有曾被掩埋经历者（OR=2．806，95％CI：1．249～6．306）、亲人丧失（OR=1．537，95％CI：1．087—2．173）及PSSS评分偏低（OR=0．960，95％CI：0．941～0．979）是PTSD发生的危险因素。结论：在灾后社区重建过程中，临时安置点社区居民存在较高的创伤后应激障碍的发生率，女性、有曾被掩埋经历、亲人丧失及个人感受到的社会支持偏低是PTSD发生的危险因素。
