为了提高说话人识别的准确率,可以同时采用多个特征参数,针对综合特征参数中各维分量对识别结果的影响可能不一样,同等对待并不一定是最优的方案这个问题,提出基于Fisher准则的梅尔频率倒谱系数(MFCC)、线性预测梅尔倒谱系数(LPMFCC)、T...为了提高说话人识别的准确率,可以同时采用多个特征参数,针对综合特征参数中各维分量对识别结果的影响可能不一样,同等对待并不一定是最优的方案这个问题,提出基于Fisher准则的梅尔频率倒谱系数(MFCC)、线性预测梅尔倒谱系数(LPMFCC)、Teager能量算子倒谱参数(TEOCC)相混合的特征参数提取方法。首先,提取语音信号的MFCC、LPMFCC和TEOCC三种参数;然后,计算MFCC和LPMFCC参数中各维分量的Fisher比,分别选出六个Fisher比高的分量与TEOCC参数组合成混合特征参数;最后,采用TIMIT语音库和NOISEX-92噪声库进行说话人识别实验。仿真实验表明,所提方法与MFCC、LPMFCC、MFCC+LPMFCC、基于Fisher比的梅尔倒谱系数混合特征提取方法以及基于主成分分析(PCA)的特征抽取方法相比,在采用高斯混合模型(GMM)和BP神经网络的平均识别率在纯净语音环境下分别提高了21.65个百分点、18.39个百分点、15.61个百分点、15.01个百分点与22.70个百分点;在30 d B噪声环境下,则分别提升了15.15个百分点、10.81个百分点、8.69个百分点、7.64个百分点与17.76个百分点。实验结果表明,该混合特征参数能够有效提高说话人识别率,且具有更好的鲁棒性。展开更多
BACKGROUND Miller fisher syndrome(MFS)is a variant of Guillain-Barrésyndrome,an acute immune-mediated peripheral neuropathy that is often secondary to viral infections.Anti-ganglioside antibodies play crucial rol...BACKGROUND Miller fisher syndrome(MFS)is a variant of Guillain-Barrésyndrome,an acute immune-mediated peripheral neuropathy that is often secondary to viral infections.Anti-ganglioside antibodies play crucial roles in the development of MFS.The positive rate of ganglioside antibodies is exceptionally high in MFS patients,particularly for anti-GQ1b antibodies.However,the presence of other ganglioside antibodies does not exclude MFS.CASE SUMMARY We present a 56-year-old female patient who suddenly developed right blepharoptosis and progressively worsening vision in both eyes.There were flu symptoms prior to onset,and a coronavirus disease 2019 test was positive.On physical examination,the patient exhibited bilateral extraocular muscle paralysis,weakened reflexes in both limbs,and impaired coordination.The cerebrospinal fluid examination results showed no obvious abnormalities.Bilateral peroneal nerve F-waves were not extracted.Serum anti-GD1b IgG and anti-GT1a IgG antibodies were positive.The patient received intravenous methylprednisolone(1000 mg/day),with the dosage gradually decreased.Additionally,intravenous high-dose immunoglobulin treatment was administered for 5 days(0.4 g/kg/day)from day 2 to day 6 of hospitalization.The patient’s symptoms improved after treatment with immunoglobulins and hormones.CONCLUSION Positive ganglioside antibodies may be used as supporting evidence for the diagnosis;however,the diagnosis of MFS is more reliant on clinical symptoms.展开更多
文摘为了提高说话人识别的准确率,可以同时采用多个特征参数,针对综合特征参数中各维分量对识别结果的影响可能不一样,同等对待并不一定是最优的方案这个问题,提出基于Fisher准则的梅尔频率倒谱系数(MFCC)、线性预测梅尔倒谱系数(LPMFCC)、Teager能量算子倒谱参数(TEOCC)相混合的特征参数提取方法。首先,提取语音信号的MFCC、LPMFCC和TEOCC三种参数;然后,计算MFCC和LPMFCC参数中各维分量的Fisher比,分别选出六个Fisher比高的分量与TEOCC参数组合成混合特征参数;最后,采用TIMIT语音库和NOISEX-92噪声库进行说话人识别实验。仿真实验表明,所提方法与MFCC、LPMFCC、MFCC+LPMFCC、基于Fisher比的梅尔倒谱系数混合特征提取方法以及基于主成分分析(PCA)的特征抽取方法相比,在采用高斯混合模型(GMM)和BP神经网络的平均识别率在纯净语音环境下分别提高了21.65个百分点、18.39个百分点、15.61个百分点、15.01个百分点与22.70个百分点;在30 d B噪声环境下,则分别提升了15.15个百分点、10.81个百分点、8.69个百分点、7.64个百分点与17.76个百分点。实验结果表明,该混合特征参数能够有效提高说话人识别率,且具有更好的鲁棒性。
文摘BACKGROUND Miller fisher syndrome(MFS)is a variant of Guillain-Barrésyndrome,an acute immune-mediated peripheral neuropathy that is often secondary to viral infections.Anti-ganglioside antibodies play crucial roles in the development of MFS.The positive rate of ganglioside antibodies is exceptionally high in MFS patients,particularly for anti-GQ1b antibodies.However,the presence of other ganglioside antibodies does not exclude MFS.CASE SUMMARY We present a 56-year-old female patient who suddenly developed right blepharoptosis and progressively worsening vision in both eyes.There were flu symptoms prior to onset,and a coronavirus disease 2019 test was positive.On physical examination,the patient exhibited bilateral extraocular muscle paralysis,weakened reflexes in both limbs,and impaired coordination.The cerebrospinal fluid examination results showed no obvious abnormalities.Bilateral peroneal nerve F-waves were not extracted.Serum anti-GD1b IgG and anti-GT1a IgG antibodies were positive.The patient received intravenous methylprednisolone(1000 mg/day),with the dosage gradually decreased.Additionally,intravenous high-dose immunoglobulin treatment was administered for 5 days(0.4 g/kg/day)from day 2 to day 6 of hospitalization.The patient’s symptoms improved after treatment with immunoglobulins and hormones.CONCLUSION Positive ganglioside antibodies may be used as supporting evidence for the diagnosis;however,the diagnosis of MFS is more reliant on clinical symptoms.
