In order to obtain the elemental compositions of the projectile and target materials during 2A12 aluminum projectile shot on a natural dolomite plate, three kinds of experiments have been conducted using a spectral ac...In order to obtain the elemental compositions of the projectile and target materials during 2A12 aluminum projectile shot on a natural dolomite plate, three kinds of experiments have been conducted using a spectral acquirement system established on a two-stage light gas gun for impact velocities ranging from 2.20 km/s to 4.20 km/s, at the same projectile incidence angle of 30°. Experimental results show that the elemental compositions of the projectile and target materials in the strong shock experiments have a good agreement with the original elemental compositions of the projectile and target. In addition, the relations between spectral radiant intensity and elemental compositions of the projectile and target materials have been obtained for different impact velocities, in which the spectral radiant intensity of the main elements in the material increases with increasing impact velocity, and more elements appear with increasing impact velocity since more energy would result from a higher velocity impact.展开更多
AIM: To investigate the effects of green flickering light on refractive development and expression of muscarinic acetylcholine receptor(mAChR) M1 in the eyes of guinea pigs.METHODS: Thirty guinea pigs(15-20 days ...AIM: To investigate the effects of green flickering light on refractive development and expression of muscarinic acetylcholine receptor(mAChR) M1 in the eyes of guinea pigs.METHODS: Thirty guinea pigs(15-20 days old) were randomly divided into three groups(n=10/group). Animals in group I were raised in a completely closed carton with green flickering light illumination. Those in group II were kept in the open top closed carton under normal natural light. Guinea pigs were raised in a sight-widen cage under normal natural light in group III. The refractive status and axial length were measured before and after 8 weeks' illumination. Moreover, total RNA extracted from retinal, choroidal, and scleral tissues were determined by real-time reverse transcription polymerase chain reaction(RT-PCR). The expressions of the receptor M1 were also explored in the retina, choroid, and sclera using immunohistochemistry.RESULTS: There was a remarkable reduction in refractive error and increase in axial length after 8-weeks' green flickering light stimulation(P〈0.001). The expression of M1 receptor mRNA in sclera and retina in myopia group were remarkably lower than that in group II and III(P〈0.01). Significant reduced expression of M1 receptor stimulated by green flickering light in retina and sclera tissues were also observed(P〈0.05). However, there was no M1 receptor expression in choroid in 3 groups.CONCLUSION: Myopia can be induced by 8 weeks' green flickering light exposure in the animal model. M1 receptor may be involved causally or protectively in myopia development.展开更多
Ever since the invention of laser pulses,^(1–5)one of the key directions for the development of laser technology has been the creation of ever shorter pulses of light.Over the past sixty years,improvements in technol...Ever since the invention of laser pulses,^(1–5)one of the key directions for the development of laser technology has been the creation of ever shorter pulses of light.Over the past sixty years,improvements in technology have pushed pulse durations down from nanoseconds through picoseconds to femtoseconds,giving us access to time-resolved studies of molecular nuclear motion and chemical reactions.^(6)Just in time for the 59th birthday of the standard(SI)prefixes“femto”and“atto,”^(7)the 2023 Nobel Prize in Physics was awarded to the latest landmark in this effort:the generation of attosecond pulses of light,^(8–10)which opens a window to the most fundamental timescale of the world around us–the timescale of electrons moving inside atoms,molecules,and condensed matter.展开更多
基金supported by National Natural Science Foundation of China(Nos.11272218,11472178)State Key Program of National Natural Science of China(No.11032003)Program for Liaoning Excellent Talents in University of China(No.LR2013008)
文摘In order to obtain the elemental compositions of the projectile and target materials during 2A12 aluminum projectile shot on a natural dolomite plate, three kinds of experiments have been conducted using a spectral acquirement system established on a two-stage light gas gun for impact velocities ranging from 2.20 km/s to 4.20 km/s, at the same projectile incidence angle of 30°. Experimental results show that the elemental compositions of the projectile and target materials in the strong shock experiments have a good agreement with the original elemental compositions of the projectile and target. In addition, the relations between spectral radiant intensity and elemental compositions of the projectile and target materials have been obtained for different impact velocities, in which the spectral radiant intensity of the main elements in the material increases with increasing impact velocity, and more elements appear with increasing impact velocity since more energy would result from a higher velocity impact.
基金Supported by Qilu Hospital of Shandong University (No.201805049)
文摘AIM: To investigate the effects of green flickering light on refractive development and expression of muscarinic acetylcholine receptor(mAChR) M1 in the eyes of guinea pigs.METHODS: Thirty guinea pigs(15-20 days old) were randomly divided into three groups(n=10/group). Animals in group I were raised in a completely closed carton with green flickering light illumination. Those in group II were kept in the open top closed carton under normal natural light. Guinea pigs were raised in a sight-widen cage under normal natural light in group III. The refractive status and axial length were measured before and after 8 weeks' illumination. Moreover, total RNA extracted from retinal, choroidal, and scleral tissues were determined by real-time reverse transcription polymerase chain reaction(RT-PCR). The expressions of the receptor M1 were also explored in the retina, choroid, and sclera using immunohistochemistry.RESULTS: There was a remarkable reduction in refractive error and increase in axial length after 8-weeks' green flickering light stimulation(P〈0.001). The expression of M1 receptor mRNA in sclera and retina in myopia group were remarkably lower than that in group II and III(P〈0.01). Significant reduced expression of M1 receptor stimulated by green flickering light in retina and sclera tissues were also observed(P〈0.05). However, there was no M1 receptor expression in choroid in 3 groups.CONCLUSION: Myopia can be induced by 8 weeks' green flickering light exposure in the animal model. M1 receptor may be involved causally or protectively in myopia development.
文摘Ever since the invention of laser pulses,^(1–5)one of the key directions for the development of laser technology has been the creation of ever shorter pulses of light.Over the past sixty years,improvements in technology have pushed pulse durations down from nanoseconds through picoseconds to femtoseconds,giving us access to time-resolved studies of molecular nuclear motion and chemical reactions.^(6)Just in time for the 59th birthday of the standard(SI)prefixes“femto”and“atto,”^(7)the 2023 Nobel Prize in Physics was awarded to the latest landmark in this effort:the generation of attosecond pulses of light,^(8–10)which opens a window to the most fundamental timescale of the world around us–the timescale of electrons moving inside atoms,molecules,and condensed matter.