BACKGROUND The strategy for preventing colorectal cancer is screening by colonoscopy,which offers a direct way for detection and removal of adenomatous polyps(APs).American College of Gastroenterology guidelines recom...BACKGROUND The strategy for preventing colorectal cancer is screening by colonoscopy,which offers a direct way for detection and removal of adenomatous polyps(APs).American College of Gastroenterology guidelines recommend that people aged≥45 years should undergo colonoscopy;however,how to deal with people aged≤45 years is still unknown.AIM To compare the prevalence of APs and high-grade neoplasia between the left and right colon in patients≤45 years.METHODS A retrospective observational study was conducted at a single tertiary III hospital in China.This study included patients aged 18-45 years with undergoing initial colonoscopy dissection and pathological diagnosis AP or high-grade neoplasia between February 2014 and January 2021.The number of APs in the entire colon while screening and post-polypectomy surveillance in following 1-3 years were evaluated.RESULTS A total of 3053 cases were included.The prevalence of APs in the left and right colon was 55.0%and 41.6%,respectively(OR 1.7,95%CI 1.6-2.4;P<0.05).For APs with high-grade neoplasia,the prevalence was 2.7%and 0.9%,respectively(OR 3.0,95%CI 2.0-4.6;P<0.05).Therefore,the prevalence of APs and high-grade neoplasia in the left colon was significantly higher than in the right colon in patients aged≤45 years.There were 327 patients who voluntarily participated in post-polypectomy surveillance in following 1-3 years,and APs were found in 216 cases(66.1%);170 cases had 1-3 polyps(52.0%)and 46 cases had>3 polyps(14.1%;OR 0.3,95%CI 0.1-0.6;P<0.05).CONCLUSION This study suggests that flexible sigmoidoscopy would be an optimal approach for initial screening in people aged≤45 years and would be a more cost-effective and safe strategy.展开更多
介绍了一种新型额定电压0.6/1 k V柔性无机矿物绝缘电力电缆,通过对用户需求的试验标准及电缆的性能指标和结构的分析研究,对新型柔性无机矿物绝缘电缆进行结构设计和材料选型,并试制样品进行试验,验证结构的合理性及可行性和耐火试验...介绍了一种新型额定电压0.6/1 k V柔性无机矿物绝缘电力电缆,通过对用户需求的试验标准及电缆的性能指标和结构的分析研究,对新型柔性无机矿物绝缘电缆进行结构设计和材料选型,并试制样品进行试验,验证结构的合理性及可行性和耐火试验标准的结合性,同时从产品的耐火试验结果性能指标稳定性、安装维护等项目指标方面,将研发的新型柔性无机矿物绝缘电缆与氧化镁矿物绝缘电缆和金属护套无机矿物绝缘电缆进行对比,充分体现了新型柔性无机矿物绝缘电缆的综合优越性。该产品可代替传统的矿物绝缘耐火电缆,具有良好的市场前景。展开更多
基金Supported by Shenzhen Science and Technology Innovation Commission Key Program of Fundamental Research,China,No.JCYJ20210324120200001Shenzhen Science and Technology Program of Shenzhen Clinical Research Center for Digestive Diseases,China,No.20220822182953001.
文摘BACKGROUND The strategy for preventing colorectal cancer is screening by colonoscopy,which offers a direct way for detection and removal of adenomatous polyps(APs).American College of Gastroenterology guidelines recommend that people aged≥45 years should undergo colonoscopy;however,how to deal with people aged≤45 years is still unknown.AIM To compare the prevalence of APs and high-grade neoplasia between the left and right colon in patients≤45 years.METHODS A retrospective observational study was conducted at a single tertiary III hospital in China.This study included patients aged 18-45 years with undergoing initial colonoscopy dissection and pathological diagnosis AP or high-grade neoplasia between February 2014 and January 2021.The number of APs in the entire colon while screening and post-polypectomy surveillance in following 1-3 years were evaluated.RESULTS A total of 3053 cases were included.The prevalence of APs in the left and right colon was 55.0%and 41.6%,respectively(OR 1.7,95%CI 1.6-2.4;P<0.05).For APs with high-grade neoplasia,the prevalence was 2.7%and 0.9%,respectively(OR 3.0,95%CI 2.0-4.6;P<0.05).Therefore,the prevalence of APs and high-grade neoplasia in the left colon was significantly higher than in the right colon in patients aged≤45 years.There were 327 patients who voluntarily participated in post-polypectomy surveillance in following 1-3 years,and APs were found in 216 cases(66.1%);170 cases had 1-3 polyps(52.0%)and 46 cases had>3 polyps(14.1%;OR 0.3,95%CI 0.1-0.6;P<0.05).CONCLUSION This study suggests that flexible sigmoidoscopy would be an optimal approach for initial screening in people aged≤45 years and would be a more cost-effective and safe strategy.
文摘介绍了一种新型额定电压0.6/1 k V柔性无机矿物绝缘电力电缆,通过对用户需求的试验标准及电缆的性能指标和结构的分析研究,对新型柔性无机矿物绝缘电缆进行结构设计和材料选型,并试制样品进行试验,验证结构的合理性及可行性和耐火试验标准的结合性,同时从产品的耐火试验结果性能指标稳定性、安装维护等项目指标方面,将研发的新型柔性无机矿物绝缘电缆与氧化镁矿物绝缘电缆和金属护套无机矿物绝缘电缆进行对比,充分体现了新型柔性无机矿物绝缘电缆的综合优越性。该产品可代替传统的矿物绝缘耐火电缆,具有良好的市场前景。