A piezoelectric pump with flexible valve has been developed to pump high viscosity cooling liquid in the nanosats thermal control system. The structure of the flexible valve is designed according to the characteristic...A piezoelectric pump with flexible valve has been developed to pump high viscosity cooling liquid in the nanosats thermal control system. The structure of the flexible valve is designed according to the characteristics of the human aortic shape with the aim to simulate the bionic pumping function of the human heart. Dynamic stress-strain features of the flexible valve are analyzed by the finite element method,and the results show that the proposed flexible valve is suitable and functional for the piezoelectric pump. Then the cylinder and diffuser/nozzle piezoelectric pumps based on flexible valves have been developed and fabricated. Experimental results of the output performance indicate that the maximum flow rate of the cylinder piezoelectric pump with flexible valve is 15.38 mL/min,170.77% higher than the diffuser/nozzle piezoelectric pump with flexible valve. The ability of the cylinder piezoelectric pump with flexible valve for transmitting high viscosity liquid has been validated. The piezoelectric pump with flexible valve has potential applications in the nanosats thermal control system.展开更多
The development of organ-on-a-chip systems demands high requirements for adequate micro-pump performance,which needs excellent performance and effective transport of active cells.In this study,we designed a piezoelect...The development of organ-on-a-chip systems demands high requirements for adequate micro-pump performance,which needs excellent performance and effective transport of active cells.In this study,we designed a piezoelectric pump with a flexible venous valve inspired by that of humans.Performance test of the proposed pump with deionized water as the transmission medium shows a maximum output flow rate of 14.95 mL/min when the input voltage is 100 V,and the pump can transfer aqueous solutions of glycerol with a viscosity of 10.8 mPa·s.Cell survival rate can reach 97.22%with a yeast cell culture solution as the transmission medium.A computational model of the electric-solid-liquid multi-physical field coupling of the piezoelectric pump with a flexible venous valve is established,and simulation results are consistent with experimental results.The proposed pump can help to construct the circulating organ-on-a-chip system,and the simple structure and portable application can enrich the design of microfluidic systems.In addition,the multi-physical field coupling computational model established for the proposed piezoelectric pump can provide an in-depth study of the characteristics of the flow field,facilitating the optimal design of the micro-pump and providing a reference for the further study of active cell transport in organ-on-a-chip systems.展开更多
基金supported by the National Natural Science Foundation of China (Nos. 51605200,61973207)the Natural Science Foundation of Shanghai(No.19ZR1474000)+1 种基金the Senior Talent Start-up Foundation of Jiangsu University(No.14JDG145)the Foundation of State Key Laboratory of Mechanics and Control of Mechanical Structures of Nanjing University of Aeronautics and Astronautics(No.MCMS-E-0320G01)。
文摘A piezoelectric pump with flexible valve has been developed to pump high viscosity cooling liquid in the nanosats thermal control system. The structure of the flexible valve is designed according to the characteristics of the human aortic shape with the aim to simulate the bionic pumping function of the human heart. Dynamic stress-strain features of the flexible valve are analyzed by the finite element method,and the results show that the proposed flexible valve is suitable and functional for the piezoelectric pump. Then the cylinder and diffuser/nozzle piezoelectric pumps based on flexible valves have been developed and fabricated. Experimental results of the output performance indicate that the maximum flow rate of the cylinder piezoelectric pump with flexible valve is 15.38 mL/min,170.77% higher than the diffuser/nozzle piezoelectric pump with flexible valve. The ability of the cylinder piezoelectric pump with flexible valve for transmitting high viscosity liquid has been validated. The piezoelectric pump with flexible valve has potential applications in the nanosats thermal control system.
基金supported by the National Natural Science Foundation of China(Grant Nos.51605200,61973207)Shanghai Rising-Star Program,China(Grant No.20QA1403900)the Natural Science Foundation of Shanghai,China(Grant No.19ZR1474000)。
文摘The development of organ-on-a-chip systems demands high requirements for adequate micro-pump performance,which needs excellent performance and effective transport of active cells.In this study,we designed a piezoelectric pump with a flexible venous valve inspired by that of humans.Performance test of the proposed pump with deionized water as the transmission medium shows a maximum output flow rate of 14.95 mL/min when the input voltage is 100 V,and the pump can transfer aqueous solutions of glycerol with a viscosity of 10.8 mPa·s.Cell survival rate can reach 97.22%with a yeast cell culture solution as the transmission medium.A computational model of the electric-solid-liquid multi-physical field coupling of the piezoelectric pump with a flexible venous valve is established,and simulation results are consistent with experimental results.The proposed pump can help to construct the circulating organ-on-a-chip system,and the simple structure and portable application can enrich the design of microfluidic systems.In addition,the multi-physical field coupling computational model established for the proposed piezoelectric pump can provide an in-depth study of the characteristics of the flow field,facilitating the optimal design of the micro-pump and providing a reference for the further study of active cell transport in organ-on-a-chip systems.
