Problems and Countermeasures to Improve Clinical Trial Participants’Compensation Rights in China

Objective To discuss the problems existing in the compensation of Chinese clinical trial participants and propose some suggestions for improving their rights.Methods The literature related to the participants’right to compensation at home and abroad was searched to study the inadequacy of the compensation right for clinical trial participants in China from four aspects:insurance system,principle of attribution,legal relationship and compensation regulations.Then,some suggestions to improve the participants’right to compensation were proposed.Results and Conclusion China lacks clear legal norms for participants’right to compensation.There are problems such as unclear insurance rules and compensation rules,unclear contractual relationships between parties to clinical trials,and no laws and regulations to rely on for attribution and compensation.China should issue regulatory guidelines related to the right to compensation of participants in clinical trials,so that all parties in clinical trials can have rules to follow if there is the occurrence of injury,which can better protect the rights and interests of the participants.

A Decision Model for Selecting Participants in Supply Chain

In order to satisfy the rapid changing requirements of customers, enterprises must cooperate with each other to form supply chain. The first and the most important stage in the forming of supply chain is the selection of participants. The article proposes a two staged decision model to select partners. The first stage is the inter company comparison in each business process to select high efficiency candidate based on inside variables. The next stage is to analyse the combination of different candidates in order to select the most perfect partners according to a goal programming model.

Practical Quantum Private Query with Classical Participants

Quantum key distribution(QKD)-based quantum private query(QPQ) is a practical application of QKD, which relaxes the security condition of perfectly concealing a private query to a cheating-sensitive strategy. We propose a QPQ protocol based on the delegated QKD scheme(DQKD-based QPQ), in which two almost ‘classical' clients(data user and database owner) can establish a 1-out-of-N oblivious key with the help of a cloud server with full quantum ability. Concretely, the two classical participants in the DQKD-based QPQ only need to access the quantum channel and reorder qubits, and the costly quantum operations, quantum state preparation and measurement are outsourced to a full quantum server in the cloud without leaking participants' privacy. The proposed protocol not only provides a cloud-based framework of QKD-based QPQ, but also obtains better security by a real-time security check, which can protect the security of the database and user against all potential attacks even if the quantum server is assumed to be a powerfully untrusted adversary.

Association between Free Triiodothyronine Levels and Peripheral Arterial Disease in Euthyroid Participants

This current cross-sectional study investigates the relationship between thyroid hormones and peripheral artery disease （PAD） among euthyroid Chinese population aged 40 years and above. Serum free triiodothyronine （FT3）, free thyroxin （FT4）, thyroid-stimulating hormone （TSH）, and thyroid antibodies were measured.

Two NGO-Run Youth-Centers in Multicultural, Socially Deprived Suburbs in Sweden—Who Are the Participants?

Objective: Leisure-time is an important part of young people’s lives. One way to reduce social differences in health is to improve adolescents’ living conditions, for example by enhancing the quality of after-school activities. Multicultural, socially deprived suburbs have less youth participation in organized leisure-time activities. This study explores who the participants are at two NGO-run youth-centers in multicultural, socially deprived suburbs in Sweden and whether socio-demographic, health-related, and leisure-time factors affect the targeted participation. Methods: The study can be seen as an explanatory mixed-methods study where qualitative data help explain initial quantitative results. The included data are a survey with youth (n = 207), seven individual interviews with staff, and six focus-groups interviews with young people at two youth-centers in two different cities. Results and Conclusions: The participants in the youth-centers are Swedish born youths having foreign-born parents who live with both parents, often in crowded apartments with many siblings. Moreover they feel healthy, enjoy school and have good contact with their parents. It seems that strategies for recruiting youths to youth-centers have a large impact on who participates. One way to succeed in having a more equal gender and ethnicity distribution is to offer youth activities that are a natural step forward from children’s activities. The youth-centers’ proximity is also of importance for participation, in these types of neighborhoods.

Safety at Work of Participants in the Railway Transport of Dangerous Goods

The transport of dangerous goods always represents a potential risk to life,human health,property,and environmental protection.For this reason and in order to preserve the lives and health of the participants in the transport process,adequate protection measures must be taken before,during,and after the transport of dangerous goods.Since the railway itself is a recipient of dangerous goods that are essential for its own operation,and is also a carrier of large quantities of various dangerous goods,these measures are of paramount importance.This paper examines,from a point of view of the protection of lives and health of the participants in the transport process and the safe transport of dangerous goods,the conditions of shipment and transport of dangerous goods,the obligations of the participants,and the essential ways for their proper handling.Proper application of safety at work prevents impromptu and indolent attitude in transporting dangerous goods,thus contributing to protection of people lives and health.Finally,this paper includes preventive measures and basic principles for implementation of safety at work in the transport of dangerous goods.

Analysis of the Differences in Expenditure Levels of Participants at the 2014 Asian Basketball League in Ho Chi Minh City

Research focuses on studying the economic impacts of 2014 Asian Basketball League in Ho Chi Minh City （hereinaiter referred as ABL 2014） with respect to direct expenditure of all types of participants, including organizers, coaches/athletes, journalists/communicators, audiences, etc. Research was implemented with 920 subjects, including 48 members of the organizing committee, 56 coaches/athletes, 800 audiences and 16 members of journal and media teams.

Athletic Participation and Academic Achievement of High School Students: A Longitudinal Study of Athletic and Non-Athletic Participants

The majority of extant research studies have established that high school students’athletic participation is positively associated with several educational outcomes,including academic performance.However,the effect of long-term athletic participation on academic performance remains unclear.Using a longitudinal data of 220 students from a high school in eastern Massachusetts of the United States,this study has revealed that athletic participants in this school started with a statistically significant higher GPA than non-participants in the first year of study,and have continued to be higher in the following two years,lag behind significantly,however,in academic achievement growth from their nonparticipation counterparts.The results of the study call for thoughtful decision-making regarding sports programs and athletic policies,proper guidance and adequate support for athletes and an optimal sport-academic culture in American high schools.

Washback and Participants in Washback Process

Research into the effects of tests on teaching and learning activities,referred to as 'washback' in the applied linguistics literature,dates back at least four decades.In this article,after giving the definition of washback,the author tries to show the relationship between washback and the participants in washback process and gives the direction for further research on washback.

A Federated Learning Framework with Blockchain-Based Auditable Participant Selection

Federated learning is an important distributed model training technique in Internet of Things(IoT),in which participant selection is a key component that plays a role in improving training efficiency and model accuracy.This module enables a central server to select a subset of participants to performmodel training based on data and device information.By doing so,selected participants are rewarded and actively perform model training,while participants that are detrimental to training efficiency and model accuracy are excluded.However,in practice,participants may suspect that the central server may have miscalculated and thus not made the selection honestly.This lack of trustworthiness problem,which can demotivate participants,has received little attention.Another problem that has received little attention is the leakage of participants’private information during the selection process.We will therefore propose a federated learning framework with auditable participant selection.It supports smart contracts in selecting a set of suitable participants based on their training loss without compromising the privacy.Considering the possibility of malicious campaigning and impersonation of participants,the framework employs commitment schemes and zero-knowledge proofs to counteract these malicious behaviors.Finally,we analyze the security of the framework and conduct a series of experiments to demonstrate that the framework can effectively improve the efficiency of federated learning.

Network analysis of the relationships between depressive symptoms and social participation activities among Chinese older adults and its implications for nursing

Objective:Network analysis was used to explore the complex inter-relationships between social participation activities and depressive symptoms among the Chinese older population,and the differences in network structures among different genders,age groups,and urban-rural residency would be compared.Methods:Based on the 2018 wave of the Chinese Longitudinal Healthy Longevity Survey(CLHLS),12,043 people aged 65 to 105 were included.The 10-item Center for Epidemiologic Studies Depression(CESD)Scale was used to assess depressive symptoms and 10 types of social participation activities were collected,including housework,tai-chi,square dancing,visiting and interacting with friends,garden work,reading newspapers or books,raising domestic animals,playing cards or mahjong,watching TV or listening to radio,and organized social activities.R 4.2.1 software was used to estimate the network model and calculate strength and bridge strength.Results:21.60%(2,601/12,043)of the participants had depressive symptoms.The total social participation score was negatively associated with depressive symptoms after adjusting for sociodemographic factors.The network of social participation and depressive symptoms showed that“D9(Inability to get going)”and“S9(Watching TV and/or listening to the radio)”had the highest strength within depressive symptoms and social participation communities,respectively,and“S1(Housework)”,“S9(Watching TV and/or listening to the radio)”,and“D5(Hopelessness)”were the most prominent bridging nodes between the two communities.Most edges linking the two communities were negative.“S5(Graden work)-D5(Hopelessness)”and“S6(Reading newspapers/books)-D4(Everything was an effort)”were the top 2 strongest negative edges.Older females had significantly denser network structures than older males.Compared to older people aged 65e80,the age group 81e105 showed higher network global strength.Conclusions:This study provides novel insights into the complex relationships between social participation and depressive symptoms.Except for doing housework,other social participation activities were found to be protective for depression levels.Different nursing strategies should be taken to prevent and alleviate depressive symptoms for different genders and older people of different ages.

Optimal dispatching strategy for residential demand response considering load participation

To facilitate the coordinated and large-scale participation of residential flexible loads in demand response(DR),a load aggregator(LA)can integrate these loads for scheduling.In this study,a residential DR optimization scheduling strategy was formulated considering the participation of flexible loads in DR.First,based on the operational characteristics of flexible loads such as electric vehicles,air conditioners,and dishwashers,their DR participation,the base to calculate the compensation price to users,was determined by considering these loads as virtual energy storage.It was quantified based on the state of virtual energy storage during each time slot.Second,flexible loads were clustered using the K-means algorithm,considering the typical operational and behavioral characteristics as the cluster centroid.Finally,the LA scheduling strategy was implemented by introducing a DR mechanism based on the directrix load.The simulation results demonstrate that the proposed DR approach can effectively reduce peak loads and fill valleys,thereby improving the load management performance.

Factors influencing willingness to participate in ophthalmic clinical trials and strategies for effective recruitment

AIM:To explore the factors influencing individuals’willingness to participate in ophthalmic clinical trials.METHODS:A questionnaire survey was conducted from January to April 2021 among patients and their family members at Zhongshan Ophthalmic Center,Sun Yat-sen University,in Guangzhou,China.The survey gathered data on respondents’willingness,demographic and socioeconomic profiles,as well as their reasons and concerns regarding engagement in clinical trials.RESULTS:Of the 1078 residents surveyed(mean age 31.2±13.1y;65.8%females)in Guangzhou,749(69.5%)expressed a willingness to participate in future ophthalmic clinical trials.Specific characteristics associated with greater willingness included a younger age,lower annual income,higher education,prior participation experience,previous ophthalmic treatment,and a better understanding of clinical trials.With the exception of age,these characteristics were significantly linked to a higher willingness.The primary barrier to participation,expressed by 64.8%of those willing and 54.4%of those unwilling,was“Uncertain efficacy”.In terms of motivations,the willing group ranked“Better therapeutic benefits”(35.0%),“Professional monitoring”(34.3%),and“Trust in healthcare professionals”(33.1%)as their top three reasons,whereas the unwilling participants indicated“Full comprehension of the protocol”(46.2%)as the key facilitator.CONCLUSION:This study reveals a substantial willingness to participate in ophthalmic clinical trials and demonstrates the predictive role of demographic and socioeconomic factors.Variations in motivators and concerns between willing and unwilling participants highlight the significance of tailored recruitment strategies.Importantly,the need for and trust in healthcare professionals stand out as powerful motivations,underscoring the importance of enhancing physician-patient relationships,adopting patient-centered communication approaches,and addressing individualized needs to improve accrual rates.

Participatory Technique Supporting Environmental Management: A Systematic and Bibliometric Review

The increasing need to manage natural resources sustainably, driven by population growth, requires the simultaneous use of Participatory Techniques (PT) and landscape planning for structured decision-making. We conducted a bibliometric and systematic review to provide an overview of PT usage, identifying evolution in scientific production. We considered the number of publications and citations, prominent journals, and highly cited articles on scientific papers published in the Web of Science database between 1993 and 2023. A total of 415 articles related to PT were identified. After content evaluation, 19 critical articles were selected that underpin the growing combined use of models and indices with PT, enhancing the robustness and credibility of decision-making processes.

Stability and accuracy of central difference method for real-time dynamic substructure testing considering mass participation coefficient

For real-time dynamic substructure testing(RTDST),the influence of the inertia force of fluid specimens on the stability and accuracy of the integration algorithms has never been investigated.Therefore,this study proposes to investigate the stability and accuracy of the central difference method(CDM)for RTDST considering the specimen mass participation coefficient.First,the theory of the CDM for RTDST is presented.Next,the stability and accuracy of the CDM for RTDST considering the specimen mass participation coefficient are investigated.Finally,numerical simulations and experimental tests are conducted for verifying the effectiveness of the method.The study indicates that the stability of the algorithm is affected by the mass participation coefficient of the specimen,and the stability limit first increases and then decreases as the mass participation coefficient increases.In most cases,the mass participation coefficient will increase the stability limit of the algorithm,but in specific circumstances,the algorithm may lose its stability.The stability and accuracy of the CDM considering the mass participation coefficient are verified by numerical simulations and experimental tests on a three-story frame structure with a tuned liquid damper.

Research on the path of effective management of participation in joint-venture railway companies by China railway group

Purpose-Following the regional restructuring,the number of joint-venture railway companies in which the Group participates has significantly increased.This paper aims to explore the challenges faced by China Railway Group in managing participation in joint-venture railway companies.The study seeks to propose specific approaches to ensure the effective management of these companies,thereby maximizing the benefits of the regional restructuring and supporting the development of a strong transportation country and a modern infrastructure system.Design/methodology/approach-Based on the change in the shareholding relationship between China Railway Group and the joint-venture railway companies,and considering the current situation of the regional restructuring of these companies,as well as the insights from existing literature and typical case studies,this paper proposes some specific paths for effective management of joint-stock railway companies which China Railway Group participated in.Findings-The problems in participation management are the unclear dual leadership role of the party committee,the lack of discourse power,the lack of synergy between shareholders,the increasing risk of sustainable operation of the loss-making companies and the role of dispatched personnel is not fully played.Based on the theories,combined with the existing research and practical cases,the paper proposed specific approaches,such as perfecting top-level system design,maintaining the discourse power,carrying out differentiated management,arranging personnel rationally,arranging shareholders synergy,and innovating methods to provide references for China Railway Group’s subsequent management of joint venture railway companies.Originality/value-This paper contributes to the existing literature by providing a comprehensive analysis of the challenges faced by China Railway Group in managing participation in joint-venture railway companies following the regional restructuring.The study offers novel insights and practical recommendations for addressing these challenges.The findings can serve as valuable references for China Railway Group’s subsequent management of joint-venture railway companies which participated in,as well as for other stateowned enterprises facing similar challenges in managing their joint ventures.

In the Middle of Global Governance Indonesia is actively participating in global governance reform through the MIKTA middle power grouping

In March 2023,Indonesia took over the chairmanship of MIKTA from Turkiye,marking the second time Indonesia has served as the rotating chair of a global governance mechanism,following the Bali G20 Summit in 2022.

Participatory Land Rehabilitation Strategies in Angacha District, Kembata Zone, Central Ethiopia Region

Community participation has become widely incorporated into policies of many soil and water conservation organizations. The purpose of this study was to assess the community participation in the rehabilitation of degraded land. In order to achieve the objective of the study, both primary and secondary data were generated by employing qualitative and quantitative data. Purposive sampling was employed to select three study kebeles (the smallest administrative structure of the country) from 16 rural kebeles in Angecha District. Simple random sampling technique was used to select 183 household heads from the lists of farmers in the selected kebeles for detailed household survey. In addition to household survey, field observation and key informant interview were also conducted to collect the necessary data. The data were presented using descriptive statistic such as percentage, frequency, tables and figure. The data collected through the use of household survey questionnaires were analyzed using logit regression while data collected through field observation and key informant interview were analyzed and interpreted using qualitative description. The findings of the present study revealed that population pressure, soil erosion, deforestation, overgrazing, and over cultivation were the major causes for land degradation. Moreover, the results of this study indicated that the main causes of the low productivity of farmland were farmers’ involvement in off-farm activities, increase in size of human population, lack of full cooperation of family members to involve in land rehabilitation practices. Households participated in rehabilitation practices at different levels, with 43.7% respondents showing intermediate participation. However, 22.4% of the farm households clarified that there is low experience sharing and motivation to participate in the process of implementation of rehabilitation programs. It is recommended that, continuous training and experience sharing program, immediate action to increase the number of literate persons, to practicing compatible practices for the agro climatic zone such as soil bund, Fanyaaju, stone bunds, and tree planting, extending effective practices, create opportunities for alternative means of livelihood and promoting NGOs effort to involve in land rehabilitation practices in the highly degraded area.

The Three Principles of Institutional Safeguards for Women's Participation in Legislation in China

The participation of women in legislation is an important aspect and means of safeguarding women’s rights.Feminist theory,based on criticism of both the“citizenship identity theory as rights”and the“citizenship identity theory as responsibilities,”proposes the“citizenship identity theory as subjectivity.”Observing the current practice of women’s participation in legislation in China,two institutional safeguard principles can be summarized:the“minimum proportion”and the“influence evaluation.”However,each of these principles has its inherent limitations.Therefore,it is necessary to supplement them with the principle of“subjective participation”in a reflective manner.This principle requires women to participate substantively in the legislative process as subjects,express women’s needs and demands,input women’s perspectives and experiences,and reconstruct the distribution of rights and responsibilities in the existing legislation.The three principles complement each other and work together to comprehensively constitute the institutional structure of women’s participation in legislation,thereby promoting the reproduction of corresponding action structures.

Factors Impacting Benefits of Participatory Forest Management in Upper Imenti Forest, Meru County, Kenya

This study focused on identifying factors affecting the benefits of Participatory Forestry Management (PFM) income generating activities in Upper Imenti Forest and whether they are dependent on status of participation in forest management through membership of Community Forest Association (CFA) or not. Cross-sectional survey research design was applied for collecting quantitative data using a semi-structured questionnaire administered to 384 households stratified on the basis of PFM participation status. Qualitative data was collected through focused group discussions using a checklist and key informant interviews using an interview schedule. Using Statistical Package for Social Sciences version 25, Binomial regression with Wald Chi-square was analyzed to identify factors perceived to be significantly influencing benefits for PFM participants and Pearson Chi-square to compare factors perceived to be affecting PFM and non-PFM participants. CFA members participation in PFM was significantly and positively affected by benefits of PFM income generating activities and forest products accessed in the forest. Benefits linked to Plantation Establishment for Livelihood Improvement System (PELIS) for CFA members were significantly reduced by enforcement of moratorium policy since February 2018, diseases and pests, poor PELIS guideline adherence and animal damage. Benefits related to state forest access for firewood by the CFA members were negatively influenced by the moratorium policy. Diseases and pests affected benefits associated with bee keeping significantly. Comparing factors under different PFM participation status, crop production was significantly affected by policy changes, pest and diseases, animal damage and PELIS guideline adherence for CFA members than for Non-CFA members. Policy changes also affected the CFA members significantly in firewood collection and access to fodder in the state forest than the Non-CFA members. Hence, sustainable community participation in Upper Imenti Forest management requires: increasing PFM benefits, addressing factors reducing benefits and enhancing active participation of CFA members in PFM related decision-making processes.