In vivo label-free measurement of blood flow velocity symmetry based on dual line scanning third-harmonic generation microscopy excited at the 1700 nm window

Measurement of bloodflow velocity is key to understanding physiology and pathology in vivo.While most measurements are performed at the middle of the blood vessel,little research has been done on characterizing the instantaneous bloodflow velocity distribution.This is mainly due to the lack of measurement technology with high spatial and temporal resolution.Here,we tackle this problem with our recently developed dual-wavelength line-scan third-harmonic generation(THG)imaging technology.Simultaneous acquisition of dual-wavelength THG line-scanning signals enables measurement of bloodflow velocities at two radially symmetric positions in both venules and arterioles in mouse brain in vivo.Our results clearly show that the instantaneous bloodflow velocity is not symmetric under general conditions.

Effects of hydrocarbon generation on fluid flow in the Ordos Basin and its relationship to uranium mineralization

The Ordos Basin of North China is not only an important uranium mineralization province, but also a major producer of oil, gas and coal in China. The genetic relationship between uranium mineralization and hydrocarbons has been recognized by a number of previous studies, but it has not been well understood in terms of the hydrodynamics of basin fluid flow. We have demonstrated in a previous study that the preferential localization of Cretaceous uranium mineralization in the upper part of the Ordos Jurassic section may have been related to the interface between an upward flowing, reducing fluid and a downward flowing, oxidizing fluid. This interface may have been controlled by the interplay between fluid overpressure related to disequilibrium sediment compaction and which drove the upward flow, and topographic relief, which drove the downward flow. In this study, we carried out numerical modeling for the contribution of oil and gas generation to the development of fluid overpressure, in addition to sedi- ment compaction and heating. Our results indicate that when hydrocarbon generation is taken into account, fluid overpressure during the Cretaceous was more than doubled in comparison with the simu- lation when hydrocarbon generation was not considered. Furthermore, fluid overpressure dissipation at the end of sedimentation slowed down relative to the no-hydrocarbon generation case. These results suggest that hydrocarbon generation may have played an important role in uranium mineralization, not only in providing reducing agents required for the mineralization, but also in contributing to the driving force to maintain the upward flow.

A comparison of different entransy flow definitions and entropy generation in thermal radiation optimization

In thermal radiation, taking heat flow as an extensive quantity and defining the potential as temperature T or the black body emissive power U will lead to two different definitions of radiation entransy flow and the corresponding principles for thermal radiation optimization. The two definitions of radiation entransy flow and the corresponding optimization prin ciples are compared in this paper. When the total heat flow is given, the optimization objectives of the extremum entransy dissipation principles （EEDPs） developed based on potentials T and U correspond to the minimum equivalent temperature difference and the minimum equivalent blackbody emissive power difference respectively. The physical meaning of the definition based on potential U is clearer than that based on potential T, but the latter one can be used for the coupled heat transfer optimization problem while the former one cannot. The extremum entropy generation principle （EEGP） for thermal radiation is also derived, which includes the minimum entropy generation principle for thermal radiation. When the radiation heat flow is prescribed, the EEGP reveals that the minimum entropy generation leads to the minimum equivalent thermodynamic potential difference, which is not the expected objective in heat transfer. Therefore, the minimum entropy generation is not always appropriate for thermal radiation optimization. Finally, three thermal radiation optimization examples are discussed, and the results show that the difference in optimization objective between the EEDPs and the EEGP leads to the difference between the optimization results. The EEDP based on potential T is more useful in practical application since its optimization objective is usually consistent with the expected one.

Numerical Simulation of Droplet Generation in Coaxial Microchannels

In this study,numerical simulations of the pinching-off phenomena displayed by the dispersed phase in a continuous phase have been conducted using COMSOL Multiphysics(level-set method).Four flow patterns,namely“drop flow”,“jet flow”,“squeeze flow”,and“co-flow”,have been obtained for different flow velocity ratios,channel diameter ratios,density ratios,viscosity ratios,and surface tension.The flow pattern map of two-phase flow in coaxial microchannels has been obtained accordingly,and the associated droplet generation process has been critically discussed considering the related frequency,diameter,and pinch-off length.In particular,it is shown that the larger the flow velocity ratio,the smaller the diameter of generated droplets and the shorter the pinch-off length.The pinch-off length of a droplet is influenced by the channel diameter ratio and density ratio.The changes in viscosity ratio have a negligible influence on the droplet generation pinching frequency.With an increase in surface tension,the frequency of generation and pinch-off length of droplets decrease,but for small surface tension the generation diameter of droplet increases.

Microchannel heat sink;Nanofluids;Entropy generation;Numerical analysis;Laminar flow

Based on the Second Law of Thermodynamics, the entropy generation is studied for laminar forced convection flow of different nanoparticles(Al_2 O_3, CuO and SiO_2) mixed with water through a hexagon microchannel heat sink(HMCHS). The effects of different heat fluxes and Reynolds numbers on the entropy generation for different nanofluids, volume fractions and nanoparticles diameter are investigated. The heat flux is in the range of 125 to 500 kW·m^(-2) and the Reynolds numbers vary between 200 and 1500. The thermal, frictional and total entropy generations are calculated by integrating the volumetric rate components over the entire HMCHS. The results clearly show that the rise in the heat flux leads to an increase in the thermal entropy generation for nanofluids and pure water but they don't have any influence on the frictional entropy generation. Moreover, when the Reynolds number increases, the frictional entropy generation increases while the thermal entropy generation decreases. The results revealed that at low heat fluxes and high Reynolds numbers, pure water gives the lowest entropy generation, while at high heat flux the nanofluid has to be used in order to lower the overall irreversibility.

Accuracy analysis of predicted velocity profiles of laminar duct flow with entropy generation method

The objective of this work is to estimate the accuracy of a predicted velocity profile which can be gained from experimental results, in comparison with the exact ones by the methodology of entropy generation. The analysis is concerned with the entropy generation rate in hydrodynamic, steady, laminar, and incompressible flow for Newtonian fluids in the insulated channels of arbitrary cross section. The entropy generation can be calculated from two local and overall techniques. Adaptation of the results of these techniques depends on the used velocity profile. Results express that in experimental works, whatever the values of local and overall entropy generation rates are close to each other, the results are more accuracy. In order to extent the subject, different geometries have been investigated. Also, the influence studied, and the distribution of volumetric geometries is drawn. of geometry on the entropy generation rate is local entropy generation rate for the selected geometries is drawn.

Effects of Combined Heat and Mass Transfer on Entropy Generation due to MHD Nanofluid Flow over a Rotating Frame

The current investigation aims to explore the combined effects of heat and mass transfer on free convection of Sodium alginate-Fe_(3)O_(4) based Brinkmann type nanofluid flow over a vertical rotating frame.The Tiwari and Das nanofluid model is employed to examine the effects of dimensionless numbers,including Grashof,Eckert,and Schmidt numbers and governing parameters like solid volume fraction of nanoparticles,Hall current,magnetic field,viscous dissipation,and the chemical reaction on the physical quantities.The dimensionless nonlinear partial differential equations are solved using a finite difference method known as Runge-Kutta Fehlberg(RKF-45)method.The variation of dimensionless velocity,temperature,concentration,skin friction,heat,and mass transfer rate,as well as for entropy generation and Bejan number with governing parameters,are presented graphically and are provided in tabular form.The results reveal that the Nusselt number increases with an increase in the solid volume fraction of nanoparticles.Furthermore,the rate of entropy generation and Bejan number depends upon the magnetic field and the Eckert number.

The effects of gas flow pattern on the generation of ozone in surface dielectric barrier discharge

Ozone production utilizing surface dielectric barrier discharge（SDBD） was experimental studied for different flow patterns considering the influences of transversal flow, lateral flow and different lateral flow positions. Results show that the flow patterns have a remarkable impact on the ozone yield by affecting the uniformity and turbulence of gas flow. Meanwhile, distributing the O2 flow rate according to the intensity of the plasma reaction would also increase the generation efficiency of SDBD for ozone production. By improving the uniformity and introducing the lateral flow to the transversal flow, the highest ozone yield was obtained in flow pattern ‘F’. In this case, the ozone yield increased by 28.4% to 131 g kWh-1 from 102.8 g k Wh-1 in flow pattern ‘A’.

Consequence of exponential heat generation on non-Darcy- Forchheimer flow of water based carbon nanotubes driven by a curved stretching sheet

The present article comprises the study on the influence of exponential space based heat generation on the non-Darcy-Forchheimer flow of carbon nanotubes(CNTs).The flow is considered over a curved stretching sheet.Similarity variables are used to reduce the flow descriptive nonlinear partial derivative equations to simple equations.Simplified equations are then solved by the exploiting Runge-Kutta-Fehlberg fourth-and fifth-order methods.Obtained numerical solutions are shown in graphs and tables.Comparison between single and multi-walled CNTs has been established through the tabulated values and plotted graphs.It is concluded that the heat source parameter plays a prime role in enhancement of temperature,and the curvature parameter has adverse impact on velocity and temperature panels.Both the inertial parameter and inverse-Darcy number affect the fluid velocity.

Entropy generation approach with heat and mass transfer in magnetohydrodynamic stagnation point flow of a tangent hyperbolic nanofluid

This work examines the entropy generation with heat and mass transfer in magnetohydrodynamic(MHD)stagnation point flow across a stretchable surface.The heat transport process is investigated with respect to the viscous dissipation and thermal radiation,whereas the mass transport is observed under the influence of a chemical reaction.The irreversibe factor is measured through the application of the second law of thermodynamics.The established non-linear partial differential equations(PDEs)have been replaced by acceptable ordinary differential equations(ODEs),which are solved numerically via the bvp4 c method(built-in package in MATLAB).The numerical analysis of the resulting ODEs is carried out on the different flow parameters,and their effects on the rate of heat transport,friction drag,concentration,and the entropy generation are considered.It is determined that the concentration estimation and the Sherwood number reduce and enhance for higher values of the chemical reaction parameter and the Schmidt number,although the rate of heat transport is increased for the Eckert number and heat generation/absorption parameter,respectively.The entropy generation augments with boosting values of the Brinkman number,and decays with escalating values of both the radiation parameter and the Weissenberg number.

Radiation Effects on Free Convection MHD Couette Flow Started Exponentially with Variable Wall Temperature in Presence of Heat Generation

Radiation effects on free convection MHD Couette flow started exponentially with variable wall temperature in the presence of heat generation have been studied. The governing equations are solved analytically using the Laplace transform technique. The variations of velocity and fluid temperature are presented graphically. It is observed that the velocity decreases with an increase in either magnetic parameter or radiation parameter or Prandtl number. It is also observed that the velocity increases with an increase in either heat generation parameter or Grashof number or accelerated parameter or time. An increase in either radiation parameter or Prandtl number leads to fall in the fluid temperature. It is seen that the fluid temperature increases with an increase in either heat generation parameter or time. Further, it is seen that the shear stress at the moving plate decreases with an increase in either magnetic parameter or radiation parameter while it increases with an increase in either heat generation parameter or Prandtl number. The rate of heat transfer increases with an increase in either Prandtl number or time whereas it decreases with an increase in heat generation parameter.

Effects of Baffle on Entropy Generation in Separated Convection Flow Adjacent to Inclined Backward-Facing Step

Numerical simulations of a two-dimensional laminar forced convection flow adjacent to inclined backward-facing step in a rectangular duct are presented to examine effects of baffle on flow, heat transfer and entropy generation distributions. The main aim of using baffles is to enhance the value of convection coefficient on the bottom wall. But the useful energy can be destroyed due to intrinsic irreversibilities in the flow by the baffle. In the present work, the amount of energy loss is estimated by the computation of entropy generation. The values of velocity and temperature which are the inputs of the entropy generation equation are obtained by the numerical solution of momentum and energy equations with blocked-off method using computational fluid dynamic technique. Discretized forms of the governing equations in the (x, y) plane are obtained by the control volume method and solved using the SIMPLE algorithm. Numerical expressions, in terms of Nusselt number, entropy generation number, Bejan number and coefficient of friction are derived in dimensionless form. Results show that although a baffle mounted onto the upper wall increases the magnitude of Nusselts number on the bottom wall, but a considerable increase in the amount of entropy generation number takes place because of this technique. For validation, the numerical results for the Nusselt number and entropy generation number are compared with theoretical findings by other investigators and reasonable agreement is found.

Effects of the profile of a supercavitating vehicle's front-end on supercavity generation

The authors designed three different front profiles for supercavitating vehicles based on cavity theory and the Granville streamlined equation are designed. Experiments were done using these front profiles in the Northwestern Polytechnical University high-speed water tunnel. The experiments indicated that the critical volume of gas required for supercavitation is affected by the axial distribution of the front-end＇s slope. The experimental data showed critical gas flow rates required for the three designs were less than rood-l, with the greatest decrease 24%. The experimental results also showed the supercavitation generation speeds of the models were faster than mod-1 by up to 32.4%. This verifies that the front profile of a supercaviting vehicle effects supercavity generation speed and critical gas flow rates. The smaller the changes in axial distribution of pressure, the higher the supercavity generation speed. The smaller the changes in curvature distribution of axial, the smaller the critical gas flow rates.

An optimization method for enhancement of gas–liquid mass transfer in a bubble column reactor based on the entropy generation extremum principle

In this study,an optimization method is proposed to enhance the gas–liquid mass transfer in bubble column reactor based on the entropy generation extremum principle.The mass transfer–induced entropy generation can be maximized with the increase of mass transfer rate,based on which the velocity field can be optimized.The oxygen gas–liquid mass transfer is the major rate–limiting step of the toluene emissions biodegradation process in bubble column reactor,so the entropy generation due to oxygen mass transfer is used as the objective function,and the conservation equations of the gas–liquid flow and species concentration are taken as constraints.This optimization problem is solved by the calculus of variations,the optimal liquid flow pattern is obtained and the relationship of the maximum mass transfer enhancement on viscous dissipation is revealed,which can be used to improve the design of internal structure of the bubble column reactor.

Differential Thermal Regimes of the Tarim and Sichuan Basins in China:Implications for Hydrocarbon Generation and Conservation

The uncertainty surrounding the thermal regimes of the ultra-deep strata in the Tarim and Sichuan basins,China,is unfavorable for further hydrocarbon exploration.This study summarizes and contrasts the present-day and paleo heat flow,geothermal gradient and deep formation temperatures of the Tarim and Sichuan basins.The average heat flow of the Tarim and Sichuan basins are 42.5±7.6 mW/m^(2)and 53.8±7.6 mW/m^(2),respectively,reflecting the characteristics of’cold’and’warm’basins.The geothermal gradient with unified depths of 0-5,000 m,0-6,000 m and 0-7,000 m in the Tarim Basin are 21.6±2.9℃/km,20.5±2.8℃/km and 19.6±2.8℃/km,respectively,while the geothermal gradient with unified depths of 0-5,000 m,0-6,000 m and 0-7,000 m in the Sichuan Basin are 21.9±2.3℃/km,22.1±2.5℃/km and23.3±2.4℃/km respectively.The differential change of the geothermal gradient between the Tarim and Sichuan basins with depth probably results from the rock thermal conductivity and heat production rate.The formation temperatures at depths of 6,000 m,7,000 m,8,000 m,9,000 m and 10,000 m in the Tarim Basin are 80℃-190℃,90℃-220℃,100℃-230℃,110℃-240℃and 120℃-250℃,respectively,while the formation temperatures at depths of 6,000 m,7,000 m,8,000 m and 9,000 m in the Sichuan Basin are 120℃-200℃,140℃-210℃,160℃-260℃and 180℃-280℃,respectively.The horizontal distribution pattern of the ultra-deep formation temperatures in the Tarim and Sichuan basins is mainly affected by the basement relief,fault activity and hydrothermal upwelling.The thermal modeling revealed that the paleo-heat flow in the interior of the Tarim Basin decreased since the early Cambrian with an early Permian abrupt peak,while that in the Sichuan Basin experienced three stages of steady state from Cambrian to early Permian,rapidly rising at the end of the early Permian and declining since the late Permian.The thermal regime of the Sichuan Basin was always higher than that of the Tarim Basin,which results in differential oil and gas generation and conservation in the ultra-deep ancient strata.This study not only promotes theoretical development in the exploration of ultra-deep geothermal fields,but also plays an important role in determining the maturation phase of the ultra-deep source rocks and the occurrence state of hydrocarbons in the Tarim and Sichuan basins.

3D UNSTRUCTURED GRID GENERATION TECH-NOLOGY & EULER SOLUTION FOR WING/FUSELAGE COMBINATION

Finite element method is based on element matrix, so regardless of whetherthe mesh is structured or unstructured, it Possesses an unified fashion of treatment. Finiteelement method in conjunction with unstructured grid will improve the ability of numericalsimulation for complicated now field. In this paper, a 3D unstructured grid generationtechno1ogy is developed and the Euler equation on the unstructured mesh for real compli-cated aircraft configurations is solved by the finite e1ement method. Numerical results in-dicate that the method presented is reliable end efficient.

Analysis and Power Quality Improvement in Hybrid Distributed Generation System with Utilization of Unified Power Quality Conditioner

This paper presents a comprehensive study that includes the sizing and power flow by series and parallel inverters in a distributed generation system(DGs)that integrates the system of hybrid wind photovoltaic with a unified power quality conditioner(UPQC).In addition to supplying active power to the utility grid,the system of hybrid wind photovoltaic functions as a UPQC,compensating reactive power and suppressing the harmonic load currents.Additionally,the load is supplied with harmonic-free,balanced and regulated output voltages.Since PVWind-UPQC is established on a dual compensation scheme,the series inverter works like a sinusoidal current source,while the parallel inverter works like a sinusoidal voltage source.Consequently,a smooth alteration from interconnected operating modes to island operating modes and vice versa can be achieved without load voltage transients.Since PV-Wind-UPQC inverters handle the energy generated through the hybrid wind photovoltaic system and the energy demanded through the load,the converters should be sized cautiously.A detailed study of the flow of power via the PV-Wind-UPQC is imperative to gain a complete understanding of the system operation and the proper design of the converters.Thus,curves that allow the sizing of the power converters according to the power flow via the converters are presented and discussed.Simulation results are presented to assess both steady state and dynamic performances of the grid connected hybrid system of PV-Wind-UPQC.This investigation is verified by simulating and analyzing the results with Matlab/Simulink.

The Measuring System for Estimation of Power of Wind Flow Generated by Train Movement and Its Experimental Testing

The measuring system for estimation of power of wind flow generated by the train movement has been created. The advantages of the proposed system are the cheapness and simple design. With its simplicity of design and easy build-up of channels, designed measuring system can be used for a wide range of technical problems. This paper describes the design process, validation and conducting the first field test of this measuring system.

Generation and Evolution of Cavitation Bubbles in Volume Alternate Cavitation(VAC)

Cavitation generation methods have been used in multifarious directions because of their diversity,and numerous studies and discussions have been conducted on cavitation generation methods.This study aims to explore the generating mechanism and evolution law of volume alternate cavitation(VAC).In the VAC,liquid water is placed in an airtight container with a variable volume.As the volume alternately changes,the liquid water inside the container continues to cavitate.Then,the mixture turbulence model and in-cylinder dynamic grid model are adopted to conduct computational fluid dynamics simulation of volume alternate cavitation.In the simulation,the cloud images at seven heights on the central axis are monitored,and the phenomenon and mechanism of height and eccentricity are analyzed in detail.By employing the cavitation flow visualization method,the generating mechanism and evolution law of cavitation are revealed.The synergistic effects of experiments and high-speed camera capturing confirm the correctness of the simulation results.In the experiment,the volume change stroke of the airtight container is set to 20 mm,the volume change frequency is 18 Hz,and the shooting frequency of the high-speed camera is set to 10000 FPS.The experimental results indicate that the position of the cavitation phenomenon has a reasonable law during the whole evolution cycle of the cavitation cloud.Also,the volume alternation cycle corresponds to the generation,development,and collapse stages of cavitation bubbles.

An Improved Method of the Energy Loss Calculation Considering the Volatility of Wind Power Generation

The energy loss of the power grid is one of the key factors affecting the economic operation of power systems. How to calculate the electric energy consumption accurately will have a great influence on the planning, operation and management of the power grid. Currently there is a mountain of theoretical methods to calculate the line loss of the power system. However, these methods have some limitation, such as less considering the volatility of wind power resources. This paper presents an improved method to calculate the energy loss of wind power generation, considering the fluctuations of wind power generation. First, data are collected to obtain the curve of the typical daily expected output of wind farms for one month. Second, the curve of the typical daily expected output are corrected by the average electricity and the shape factor to obtain the curve of the typical daily equivalent output of wind farms for one month. Finally, the power flow is calculated by using typical daily equivalent output curve to describe the energy loss for one month. The results in the 110 kV main network show that the method is feasible.