Using a titration setup to accurately control the reaction conditions and in situ monitor the reaction,we showed that fluoride exhibited negligible effects on the ion association process of calcium and phosphate and t...Using a titration setup to accurately control the reaction conditions and in situ monitor the reaction,we showed that fluoride exhibited negligible effects on the ion association process of calcium and phosphate and the formation of ACP nanospheres in a buffer solution with constant ionic strength.However,the stability of ACP increased with increasing fluoride concentration,which was ascribed to the inhibitory effect of fluoride on the aggregation of ACP nanospheres and the nucleation of nanocrystals on the surface of ACP nanospheres.Furthermore,fluoride could inhibit the lateral growth of HAP nanosheets and promote the formation of rod-like crystals.These results further improve our understanding of the crystallization pathway of HAP crystals and the regulatory effects of fluoride.展开更多
The aim of this work was to produce a nanoscale fluoridated and potassium containing hydroxyapatite via sol-gel method and to observe the effect of occlusion of the dentin tubule under scanning electron microscopy. H...The aim of this work was to produce a nanoscale fluoridated and potassium containing hydroxyapatite via sol-gel method and to observe the effect of occlusion of the dentin tubule under scanning electron microscopy. HF was selected as fluorine-containing rengent which was added into mixed Ca （ NO3 ）2-P2O5 ethanol solutions to obtain dipping sols. All of the resulting samples showed apatite structure in their X- ray diffraction pattern. The lattice parameter a and the crystallite size were calculated to demonstrate the crystalline structure of fluoridated and potassium containing HA. Extracted paired premolars were chosen to obtain a fiat surface with opened tubules. It was observed that the tubules were covered by a 10 μm layer of fluoridated and potassium containing HA under the SEM. As the experimental results show the nanoscale fluoridated and potassium containing hydroxyapatite occludes the dentin tubules.展开更多
基金Funded by the National Natural Science Foundation of China(No.52172287)the National Key Research and Development Program of China(No.2021YFA0715700)。
文摘Using a titration setup to accurately control the reaction conditions and in situ monitor the reaction,we showed that fluoride exhibited negligible effects on the ion association process of calcium and phosphate and the formation of ACP nanospheres in a buffer solution with constant ionic strength.However,the stability of ACP increased with increasing fluoride concentration,which was ascribed to the inhibitory effect of fluoride on the aggregation of ACP nanospheres and the nucleation of nanocrystals on the surface of ACP nanospheres.Furthermore,fluoride could inhibit the lateral growth of HAP nanosheets and promote the formation of rod-like crystals.These results further improve our understanding of the crystallization pathway of HAP crystals and the regulatory effects of fluoride.
文摘The aim of this work was to produce a nanoscale fluoridated and potassium containing hydroxyapatite via sol-gel method and to observe the effect of occlusion of the dentin tubule under scanning electron microscopy. HF was selected as fluorine-containing rengent which was added into mixed Ca （ NO3 ）2-P2O5 ethanol solutions to obtain dipping sols. All of the resulting samples showed apatite structure in their X- ray diffraction pattern. The lattice parameter a and the crystallite size were calculated to demonstrate the crystalline structure of fluoridated and potassium containing HA. Extracted paired premolars were chosen to obtain a fiat surface with opened tubules. It was observed that the tubules were covered by a 10 μm layer of fluoridated and potassium containing HA under the SEM. As the experimental results show the nanoscale fluoridated and potassium containing hydroxyapatite occludes the dentin tubules.
