(R)-N-(β-Trichlorogermyl propionyl)thiazolidine-2-thione-4-carboxylic methyl ether(1) and its sesquioxide(2) were synthesized. The crystal structure of 1 was determined by means of X-ray diffraction analysis, which s...(R)-N-(β-Trichlorogermyl propionyl)thiazolidine-2-thione-4-carboxylic methyl ether(1) and its sesquioxide(2) were synthesized. The crystal structure of 1 was determined by means of X-ray diffraction analysis, which shown that the >CO and >CS groups are located in the opposite sides of C(4)—N—C(3) bond with transconfiguration. The electronic structures and optimized configurations of compounds 1 and 2 were studied with MNDO method.展开更多
potential chiral auxilliary, (+)-camphor derived N-propionyl sultam, wassynthesized from (+ )-camphor-10-sulphonyl chloride in four steps with enan-tiomerical purity. The molecular and crystal structures of the title ...potential chiral auxilliary, (+)-camphor derived N-propionyl sultam, wassynthesized from (+ )-camphor-10-sulphonyl chloride in four steps with enan-tiomerical purity. The molecular and crystal structures of the title compound weredetermined by single crystal diffraction analysis. The crystal belongts to monoclin-ic , space group P2_1 with cell dimentions a= 1. 0502(4) , b= 0. 7252(1 ) , c= 0. 9363(2) nm, β= 108. 3(5) , V = 0. 677 nm￣3, F(000) = 292 and Z= 2. The structuralcharacteristics with respect to the potential utility for the stereoselective alkylationat a-carbon of the N-propionyl group are discussed and explained based on ￣1H-, ￣(13)C-NMR. MS and X-ray analysis.展开更多
1, 4-Bis[3-N-propionyl-2-aryl-1, 3, 4-oxadiazoline-5-yl]phenylenes 4 were synthesized by cyclization of corresponding hydrazones 3 with propionic anhydride.
This paper studied the deactivation of propionyl shikonin(PS) to tobacco mosaic virus(TMV).After preparation and isolation of TMV coat protein(CP),concentration and purity test were made by SDS-PAGE and MALDI-TOF MS.B...This paper studied the deactivation of propionyl shikonin(PS) to tobacco mosaic virus(TMV).After preparation and isolation of TMV coat protein(CP),concentration and purity test were made by SDS-PAGE and MALDI-TOF MS.Bonding of PS and TMV-CP was determined also by MALDI-TOF MS.Peptide mass spectra of trypsin enzymolysis treated by propionyl shikonin were studied.Based on the rate of changes of peptide relative abundance of TMV-CP bonding with PS,the bonding site was computed with SGI workstation,the pKa value was 4.95.展开更多
文摘(R)-N-(β-Trichlorogermyl propionyl)thiazolidine-2-thione-4-carboxylic methyl ether(1) and its sesquioxide(2) were synthesized. The crystal structure of 1 was determined by means of X-ray diffraction analysis, which shown that the >CO and >CS groups are located in the opposite sides of C(4)—N—C(3) bond with transconfiguration. The electronic structures and optimized configurations of compounds 1 and 2 were studied with MNDO method.
文摘potential chiral auxilliary, (+)-camphor derived N-propionyl sultam, wassynthesized from (+ )-camphor-10-sulphonyl chloride in four steps with enan-tiomerical purity. The molecular and crystal structures of the title compound weredetermined by single crystal diffraction analysis. The crystal belongts to monoclin-ic , space group P2_1 with cell dimentions a= 1. 0502(4) , b= 0. 7252(1 ) , c= 0. 9363(2) nm, β= 108. 3(5) , V = 0. 677 nm￣3, F(000) = 292 and Z= 2. The structuralcharacteristics with respect to the potential utility for the stereoselective alkylationat a-carbon of the N-propionyl group are discussed and explained based on ￣1H-, ￣(13)C-NMR. MS and X-ray analysis.
文摘1, 4-Bis[3-N-propionyl-2-aryl-1, 3, 4-oxadiazoline-5-yl]phenylenes 4 were synthesized by cyclization of corresponding hydrazones 3 with propionic anhydride.
文摘This paper studied the deactivation of propionyl shikonin(PS) to tobacco mosaic virus(TMV).After preparation and isolation of TMV coat protein(CP),concentration and purity test were made by SDS-PAGE and MALDI-TOF MS.Bonding of PS and TMV-CP was determined also by MALDI-TOF MS.Peptide mass spectra of trypsin enzymolysis treated by propionyl shikonin were studied.Based on the rate of changes of peptide relative abundance of TMV-CP bonding with PS,the bonding site was computed with SGI workstation,the pKa value was 4.95.
基金supported by the National Natural Science Foundation of China(50773070)National Key Basic Research Program of China(973)(2005CB623902)Grand Science and Technology Special Project of Zhejiang Province,China(2008C11087)~~
