A facile, efficient and novel approach to access 2-substituted-N1-carbethoxy-2,3-dihydro-4（1H）-quinazolinones was developed by condensation of substituted N-carbethoxyanthranilamide with alkyl, aromatic or heteroaro...A facile, efficient and novel approach to access 2-substituted-N1-carbethoxy-2,3-dihydro-4（1H）-quinazolinones was developed by condensation of substituted N-carbethoxyanthranilamide with alkyl, aromatic or heteroaromatic aldehydes in the refluxing 2,2,2- trifluoroethanol or hexafluoroisopropanol using p-toluenesulfonic acid as catalyst.展开更多
基金We are grateful to the National Natural Science Foundation of China(No.30672540)the Natural Science Foundation of Beijing(No.7072048)for financial support.
文摘A facile, efficient and novel approach to access 2-substituted-N1-carbethoxy-2,3-dihydro-4（1H）-quinazolinones was developed by condensation of substituted N-carbethoxyanthranilamide with alkyl, aromatic or heteroaromatic aldehydes in the refluxing 2,2,2- trifluoroethanol or hexafluoroisopropanol using p-toluenesulfonic acid as catalyst.
