Effect of Brisk Walking on Self-Care Agency or Care Dependency among Colorectal Cancer Patients with Permanent Stoma

Objective:The purpose of this study was to determine the effectiveness of brisk walking as an intervention for self-care agency and care dependency in patients with permanent colorectal cancer stoma.Method:This study adopted a quasi-experimental research design,specifically a non-equivalent control group pre-test and post-test design.Utilizing the Exercise of Self-Care Agency Scale(ESCA)and Care Dependency Scale(CDS),a survey was administered to 64 patients from a hospital in Shandong Province.The statistical methods used for analyzing data included frequency,mean,standard deviation(SD),independent t-test,P-value calculation,and dependent t-test.Result:After two months of a brisk walking exercise program,participants in the experimental group had a higher level of self-care agency than before the experiment(P<0.05),and their level of care dependency was significantly reduced(P<0.05).Participants in the control group also showed higher levels of self-care agency(P<0.05)and lower levels of care dependency(P<0.05)after two months compared to their levels before the two months.Conclusion:The brisk walking program had a positive impact on patients’self-care agency and reduced their care dependency.

Analyzing Ethereum Smart Contract Vulnerabilities at Scale Based on Inter-Contract Dependency

Smart contracts running on public blockchains are permissionless and decentralized,attracting both developers and malicious participants.Ethereum,the world’s largest decentralized application platform on which more than 40 million smart contracts are running,is frequently challenged by smart contract vulnerabilities.What’s worse,since the homogeneity of a wide range of smart contracts and the increase in inter-contract dependencies,a vulnerability in a certain smart contract could affect a large number of other contracts in Ethereum.However,little is known about how vulnerable contracts affect other on-chain contracts and which contracts can be affected.Thus,we first present the contract dependency graph(CDG)to perform a vulnerability analysis for Ethereum smart contracts,where CDG characterizes inter-contract dependencies formed by DELEGATECALL-type internal transaction in Ethereum.Then,three generic definitions of security violations against CDG are given for finding respective potential victim contracts affected by different types of vulnerable contracts.Further,we construct the CDG with 195,247 smart contracts active in the latest blocks of the Ethereum and verify the above security violations against CDG by detecting three representative known vulnerabilities.Compared to previous large-scale vulnerability analysis,our analysis scheme marks potential victim contracts that can be affected by different types of vulnerable contracts,and identify their possible risks based on the type of security violation actually occurring.The analysis results show that the proportion of potential victim contracts reaches 14.7%,far more than that of corresponding vulnerable contracts(less than 0.02%)in CDG.

Escaping Dependency and Trade War:China and the US

Marxist political economy provides a perspective for grasping the root cause of the China-US trade war.The international relations of production,which stem from the international division of labor,shape the distribution of international economic interests and the political status of countries.Traditionally,developing countries have been subjected to the“periphery”in the international division of labor.In the new global value chain,developing countries have remained in a subordinate position characterized by“technological-market”dependence.To achieve the goal of building a strong modern nation,China must escape the“technological-market”dependence.Yet China’s efforts and achievements in escaping dependent development are deemed as a threat to US vested interests in the international markets.To preserve the economic foundation of its hegemony,the US has resorted to a trade war to contain China’s development.

Reliability modeling of mutual DCFP considering failure physical dependency

Degradation and overstress failures occur in many electronic systems in which the operation load and environmental conditions are complex.The dependency of them called dependent competing failure process(DCFP),has been widely studied.Electronic system may experience mutual effects of degradation and shocks,they are considered to be interdependent.Both the degradation and the shock processes will decrease the limit of system and cause cumulative effect.Finally,the competition of hard and soft failure will cause the system failure.Based on the failure mechanism accumulation theory,this paper constructs the shock-degradation acceleration and the threshold descent model,and a system reliability model established by using these two models.The mutually DCFP effect of electronic system interaction has been decomposed into physical correlation of failure,including acceleration,accumulation and competition.As a case,a reliability of electronic system in aeronautical system has been analyzed with the proposed method.The method proposed is based on failure physical evaluation,and could provide important reference for quantitative evaluation and design improvement of the newly designed system in case of data deficiency.

Quality Control at Nomophobia and Dependency to Technological

This study aims to investigate the phenomenon of technological gadget usage among pre-university students,which include the time spent using them,as well as their purpose and influence.A descriptive research design was adopted in this study.131 pre-university students were randomly selected to answer a structured questionnaire.They were informed two weeks earlier to keep track on their time spent on technological devices,before answering the questionnaire.Findings showed that 99.2%of the respondents owned at least two technological gadgets,and all respondents own a smartphone.The main two gadgets that respondents spend at least 4 h a day on are smartphones(65.6%)and computers/laptops(21.4%).This indicates that smartphones are commonly used and owned among the respondents.The majority of the respondents are moderately nomophobia and moderately dependent on smartphones(70.2%and 66.4%,respectively).Correlation analysis demonstrates that the total time spent on gadgets in a day has a significant positive correlation with gadget dependency and total number of gadgets owned.Meanwhile,logistic regression was conducted to estimate the probability of nomophobia and dependency using total time spent and total number of technological gadgets.From thefindings,it was demonstrated that when the total time spent on using technological gadgets increasing,there is greater probability that the respondents develop nomophobia and dependency.This indicates that nomophobia and dependency to technological gadgets can be used to predict lifestyle profiles.The use of technological gadgets can bring both benefit and harm to its user.In light of this,user has to remain rational in order to derive maximum benefit from it.

Read-Write Dependency Aware Register Allocation

Read-write dependency is an important factor restricting software efficiency.Timing Speculative(TS)is a processing architecture aiming to improve energy efficiency of microprocessors.Timing error rate,influenced by the read-write dependency,bottlenecks the voltage down-scaling and so the energy efficiency of TS processors.We proposed a method called Read-Write Dependency Aware Register Allocation.It is based on the Read-Write Dependency aware Interference Graph(RWDIG)conception.Registers are reallocated to loosen the read-write dependencies,so resulting in a reduction of timing errors.The traditional no operation(Nop)padding method is also redesigned to increase the distance value to above 2.We analyzed the dependencies of registers and maximized the average distance value of read and write dependencies.Experimental results showed that we can reduce all read-write dependency by Nop padding,as well as the overhead timing errors.An energy saving of approximately 7%was achieved.

微服务系统服务依赖发现技术综述

微服务架构得到了广泛的部署与应用,提升了软件系统开发的效率,降低了系统更新与维护的成本,提高了系统的可扩展性.但微服务变更频繁、异构融合等特点使得微服务故障频发、其故障传播快且影响大,同时微服务间复杂的调用依赖关系或逻辑依赖关系又使得其故障难以被及时、准确地定位与诊断,对微服务架构系统的智能运维提出了挑战.服务依赖发现技术从系统运行时数据中识别并推断服务之间的调用依赖关系或逻辑依赖关系,构建服务依赖关系图,有助于在系统运行时及时、精准地发现与定位故障并诊断根因,也有利于如资源调度、变更管理等智能运维需求.首先就微服务系统中服务依赖发现问题进行分析,其次,从基于监控数据、系统日志数据、追踪数据等3类运行时数据的角度总结分析了服务依赖发现技术的技术现状;然后,以基于服务依赖关系图的故障根因定位、资源调度与变更管理等为例,讨论了服务依赖发现技术应用于智能运维的相关研究.最后,对服务依赖发现技术如何准确地发现调用依赖关系和逻辑依赖关系,如何利用服务依赖关系图进行变更治理进行了探讨并对未来的研究方向进行了展望.

Percolation transitions in edge-coupled interdependent networks with directed dependency links

We propose a model of edge-coupled interdependent networks with directed dependency links(EINDDLs)and develop the theoretical analysis framework of this model based on the self-consistent probabilities method.The phase transition behaviors and parameter thresholds of this model under random attacks are analyzed theoretically on both random regular(RR)networks and Erd¨os-Renyi(ER)networks,and computer simulations are performed to verify the results.In this EINDDL model,a fractionβof connectivity links within network B depends on network A and a fraction(1-β)of connectivity links within network A depends on network B.It is found that randomly removing a fraction(1-p)of connectivity links in network A at the initial state,network A exhibits different types of phase transitions(first order,second order and hybrid).Network B is rarely affected by cascading failure whenβis small,and network B will gradually converge from the first-order to the second-order phase transition asβincreases.We present the critical values ofβfor the phase change process of networks A and B,and give the critical values of p andβfor network B at the critical point of collapse.Furthermore,a cascading prevention strategy is proposed.The findings are of great significance for understanding the robustness of EINDDLs.

装配式建筑结构顶升逆作法原理与技术发展

顶升逆作法综合了顶升和逆作法两种技术的不同特性,是一种在邻近地面对建筑逐层建造并逐层顶升的新型建造工艺。通过对顶升各阶段的原理分析,结合强时变结构特点,对顶升点选择等关键技术进行研究,分析了竖向顶升位移不同步工况下的结构受力机理,厘清了装配式建筑结构顶升逆作法的受力特点,梳理了现有的相关配套技术,指出了目前装配式建筑结构顶升逆作法待解决的技术难题。针对新型建造工艺的强时变特征,提出了结合数字孪生和人工智能两种技术进行智能调控的发展趋势,构建了面向减碳优化的综合目标函数,并通过算例证明合理的顶升方案对减少建造阶段构件内力的作用。结果表明:依托装配式建筑结构顶升逆作法原理,采用机械化施工取代人工作业、大重量顶升替换高空吊运,减少设备的层间转运和材料的竖向运输,能够在提高施工建造效率的同时,将工艺流程控制在临近地面的有效高度范围内,有望降低环境影响、减少碳排放、提高建筑结构在未来服役末期的资源化可行性,助力建筑业绿色低碳发展。

基于互补性和依存度的中印农产品贸易合作研究

选取2002—2020年中国和印度农产品贸易数据,采用贸易互补性指数、产业内贸易指数、贸易结合度指数等对中印农产品贸易的互补性和依存度进行了测度,同时分析了两国的农产品贸易合作关系。结果表明:中印农产品在世界市场上的贸易互补性较低;双边贸易过程中印度对中国的农产品贸易互补性较强,中国对印度的农产品贸易互补性较低。中印农产品以产业间贸易为主,仅园艺产品的产业内贸易水平较高,并逐渐由垂直型转向水平型产业内贸易。中印在蔬菜、棉花等20种农产品具有产业间贸易互补空间,7种竞争性农产品中有2种具有产业内贸易互补空间。中印农产品贸易依存度较低,且中国对印度的农产品贸易依存度更低。根据研究结论,提出了加强中印发展战略对接、深化两国在农业领域的合作,充分发挥中印各自农产品比较优势、优化农产品贸易结构,努力提高农产品质量和差异化、推动中印农产品产业内贸易发展等对策建议。

融合情感语义与句法结构的中文开放域事理图谱构建研究

为解决大规模开放域事理图谱构建过程中缺少标注数据以及事件类型未知导致的限定域事理图谱构建方法难以迁移的问题,利用规则匹配方法高效识别开放域文本中包含的多种事件逻辑关系,融合情感语义与句法结构信息分析提高事件抽取准确性,以更好完成事理图谱的构建任务。首先,总结并扩展因果、顺承、条件、转折等多种逻辑关系抽取模板,并基于规则模板、依存句法信息筛选逻辑关系事件句;其次,创新性地引入情感语义分析方法,在句法结构信息的基础上,通过捕获事件及事件间关系的情感语义精准识别事件类型,进而抽取事件论元;再次,计算语义相似度,进行事件融合,构建<前序事件,事件逻辑关系,后序事件>三元组,得到事件事理图谱,并进一步进行事件泛化以构建抽象事理图谱;最后,以事件发展较完整的“2022年猴痘事件”为数据源,通过实证分析证明开放域事理图谱构建方法可以实现不同类型事件的识别、事件间逻辑关系的揭露,其有效性、可行性得到验证。研究不仅弥补了现有事理图谱构建理论的不足,也为决策支持、事件发展预测等提供有力的数据支持。

延迟退休对青年人就业的挤入效应研究

本文从理论上提出了延迟退休对青年人就业产生挤入效应的两条途径,并基于2005年1%人口抽样调查微观数据和2010年第六次全国人口普查微观数据,采用双向固定效应模型实证研究了延迟退休对青年人就业的影响及作用机制。研究结果显示:延迟退休不仅不会挤出青年人就业,反而会对其产生挤入效应。异质性分析结果表明,相较于男性青年人,延迟退休对女性青年人就业的促进作用偏弱;高学历老年人延迟退休能够促进高学历青年人就业,低学历老年人延迟退休能够促进低学历青年人就业。机制分析结果表明,延迟退休通过降低实际老年抚养比促进青年人就业。调节效应分析结果表明,经济发展水平对延迟退休与青年人就业之间的关系存在正向调节效应。本文的研究结论支持政府为增加劳动力供给提出的延迟退休政策,建议推进渐进式、弹性式延迟退休政策。在实行延迟退休政策的同时,政府应适时调整其他相关政策。在三孩生育政策全面放开阶段,政府应重视年轻家庭对祖辈隔代照料的需求。此外,政府应鼓励老年劳动力提升自身人力资本水平。

论数字资本主义时代的技术异化

进入数字资本主义时代,技术与资本最大限度的联袂合谋将人们推入数字化生存境地,数字技术最广程度地渗透和浸润到社会生活的各个方面,最大程度地改变了人们的劳动过程、消费模式和交往范式。资本对技术的调用和技术与资本的合谋催生了技术的晦暗面和技术异化,造成了劳动过程的剥削循环、消费需求的虚假过溢和社会交往的虚拟泛化,将人类社会置于技术依赖和数字化生存的困境。消解技术异化和超拔技术生存困境,需要深刻检审数字资本主义时代的技术异化现象,废除资本主义私有制,拆解和打破资本对技术的调用以及技术与资本的联姻,重塑自由劳动过程、归正消费需求取向和复归社会交往真谛,从而使技术朝向为人的解放和自由全面发展的方向服务。

深部直墙半圆拱巷道围岩时效损伤劣化特征与动态补强技术

随着煤矿开采向深部逐渐延伸,巷道的大变形和长时间持续流变特性已成为支护中极具挑战的课题之一。为了探究深部巷道围岩损伤劣化的时效特征及动态补强技术,基于实验室试验,并结合理论分析、数值模拟及现场工业试验进行了研究。研究结果表明:(1)基于Laplace逆变换推导出圆形轴对称巷道的变形规律解析解,结合理论分析、非圆形巷道等效变换和现场试验确定塑性区半径为1.5~2.1m,进一步得到直墙半圆拱巷道时效变形解析解;(2)基于弹性与弹塑性巷道模型,采用能量耗散表征了围岩损伤劣化的时效特征与塑性区演化趋势,并提出了一次支护的时机;(3)阐明了围岩在一次支护后的时效性损伤劣化的演化趋势,基于垂直应力峰值比率,提出了二次支护方案与时机,进一步分析围岩剪应力与垂直应力,确定了二次支护锚杆的长度为3.0 m,支护时机为40~70 d。研究结果可为深部煤矿巷道的设计与维护提供理论依据和实践指导。

基于FAERS数据库的周期蛋白依赖性激酶4/6抑制剂血液毒性真实世界研究

目的 基于美国美国食品药品管理局(FDA)的不良事件报告系统(FAERS)分析3种周期蛋白依赖性激酶4/6(CDK4/6)抑制剂上市后的不良事件(AEs)信号,为临床用药安全提供参考。方法 提取FAERS数据库2015年第一季度至2022年第一季度共29个季度AEs,利用报告比值比法(ROR)和比例报告比值法(PRR)对CDK4/6抑制剂AEs进行数据挖掘。结果 CDK4/6抑制剂相关性血液毒性报告共有7 872份,各抑制剂血液毒性AEs占总AEs比例依次为哌柏西利(80.31%)>瑞博西利(15.36%)>阿贝西利(4.33%)。血液毒性常见中性粒细胞减少和贫血。哌柏西利(2 982/6 322,47.17%)和瑞博西利(613/1 209,50.70%)致中性粒细胞减少的报告占比较阿贝西利(117/341,34.31%)更高,血液毒性主要发生在药物开始使用后60 d内(1 630,61.86%),哌柏西利中位时间最长,且用药90 d后仍有32.9%的患者存在血液毒性,不同CDK4/6抑制剂血液毒性临床表现及发生强度存在差异。结论 哌柏西利、阿贝西利、瑞博西利均会导致明显的血液毒性,其中阿贝西利致血液毒性报告最少,但要警惕阿贝西利致贫血后导致死亡的风险。用药后的2个月内密切监测全血细胞计数,关注中性粒细胞、血红蛋白等水平,警惕CDK4/6抑制剂相关血液AEs的发生。

政策网络视角下县域教师交流政策的执行困境与破解路径——基于辽宁省T县的案例研究

教师交流是促进义务教育均衡发展的关键举措。本研究立足于辽宁省T县义务教育教师交流政策执行调研实况,利用政策网络理论分析框架,分析教师交流政策主体间的互动关系对政策执行成效的影响机制。研究发现,县域教师交流政策网络主体主要包括政策社群网络、府际网络、校际网络和议题网络,各网络主体之间的互动关系对县域教师交流政策执行成效具有显著影响作用。县域教师交流政策执行面临着政策社群网络内部的部门协同不畅、政策社群网络与府际网络间的利益取向冲突、校际网络内部的资源流动不畅、议题网络的参与程度不高等四大困境。基于此,破解县域教师交流政策执行中所面临的困境应畅通政策社群网络内部的跨部门合作通道,稳固跨部门合作关系;按照纵向职责同构原则,明确政策社群网络和府际网络的职责分工;调整校际网络内部的互动模式,疏通县乡学校交流渠道;畅通议题网络参与渠道,激发议题网络规模效应;调整校际网络内部的互动模式,疏通县乡学校交流渠道;畅通议题网络参与渠道,激发议题网络的规模效应。

资源依赖下社会组织参与社区微治理的自主性何以生成?——以上海市Y组织为例

我国社会组织对其他主体尤其是政府主体存在资源依赖,这对其自主性有所限制。已有研究对社会组织自主性的理解和操作化集中于社会组织的财务、人事、组织发展规划等方面,但对其业务活动过程中的自主性讨论较少且与其他方面自主性的区分不够。聚焦Y组织在参与社区微治理过程中的自主性进行研究,发现在面向不同主体时,社会组织谋求自主性的主导逻辑有所不同:因对街道的资源依赖程度较深,Y组织采取“有底线地遵从”策略以管理对街道的资源依赖,并以专业逻辑为主导获得自主性;面对社区相关利益主体时,Y组织采取“操纵式地满足”策略,并以合法性逻辑为主导,拓展其在社区中的自主性。

部分饱和岩石的黏弹性Chapman-Kelvin模型的正演模拟方法研究

在讨论地震波传播理论时,大部分情况下是把地震波看作弹性波.事实上,地下介质是非完全弹性介质,这使得传统的均匀、完全弹性介质理论受到了严重挑战.地震波在裂隙岩石中传播受裂隙系统和流体含量的影响较大,以往许多关于频变各向异性的理论大多局限于单相流体假设,但是几乎所有储层中通常被一种以上的流体部分饱和或完全饱和.本文在Chapman理论基础上,提出了基于部分饱和的黏弹性Chapman-Kelvin模型的正演模拟新方法,以提高对部分饱和岩石的黏弹性地震波频变各向异性的认识.该方法基于Chapman和Kelvin理论模型,计算了双相不混溶流体饱和裂隙岩石中的黏弹性波频变各向异性弹性系数的表达式,提出包含喷射流和斑块效应的统一地震波传播的黏弹性Chapman-Kelvin新模型.通过对新模型进行数值试验,讨论了无裂缝和存在裂缝两种情况下,含裂隙储层部分饱和岩石中耦合的喷射流和斑块效应对黏弹性介质频变各向异性的影响.试验结果反映出黏弹性介质下地震波频变各向异性的变化规律,验证了本文提出的新方法和新模型正确.本文将黏弹性介质各向异性与裂缝中的流体流动参数相联系,有利于提高对含裂缝储层部分饱和岩石的黏弹性波频变地震各向异性的认识,以及地震学与油藏工程的结合程度.

c-Myc、CDK12在胃癌组织中的表达及临床意义

目的 探讨胃癌组织中c-Myc、细胞周期蛋白依赖性激酶12(CDK12)表达及其与患者临床特征及预后的关系。方法 收集80例胃癌患者的胃癌组织和癌旁组织标本,采用免疫组化法检测标本中的c-Myc、CDK12表达水平。比较胃癌组织和癌旁组织中c-Myc、CDK12阳性表达情况;分析胃癌组织中c-Myc、CDK12阳性表达与患者临床病理特征的关系;分析c-Myc与CDK12阳性表达的相关性,胃癌组织中c-Myc、CDK12阳性表达与胃癌患者预后的关系。结果 胃癌组织中c-Myc、CDK12阳性表达率(77.5%、87.5%)均明显高于癌旁组织(13.8%、15.0%)(P<0.05)。不同年龄、性别、肿瘤最大直径患者胃癌组织中c-Myc、CDK12阳性表达率比较差异无统计学意义(P>0.05);中低分化、Ⅲ~Ⅳ期、侵犯浆膜、有淋巴结转移患者胃癌组织中c-Myc和CDK12阳性表达率分别为88.0%、87.0%、88.9%、90.0%和94.0%、92.6%、97.2%、100.0%,均明显高于高分化、Ⅰ~Ⅱ期、未侵犯浆膜、无淋巴结转移患者胃癌组织的60.0%、57.7%、68.2%、70.0%和76.7%、76.9%、79.5%、80.0%(P<0.05)。相关分析发现,c-Myc、CDK12在胃癌组织中的表达呈正相关性(r=0.487,P=0.016<0.05)。胃癌组织中c-Myc、CDK12阳性患者的3年生存率分别为19.4%、21.4%,均明显低于c-Myc、CDK12阴性患者的55.6%、70.0%(P<0.05)。结论 c-Myc、CDK12在胃癌组织中异常高表达,两者呈正相关性,并与肿瘤的TNM分期、分化程度、肿瘤侵袭深度及淋巴结转移有关,对患者的预后有明显影响,通过检测两者水平可能评估胃癌患者的预后。

多重连接探针扩增技术在食品安全检测中的应用研究进展

阐述了多重连接探针扩增(MLPA)技术在食品过敏原检测、食品掺假、食源性致病菌和转基因食品检测中的应用现状,并对该技术在食品安全检测领域的发展趋势和挑战进行展望。