Detection of Atrazine Residue in Food Samples by a Monoclonal Antibody-based Enzyme-linked Immunosorbent Assay

Atrazine（AT,2-chloro-4-ethylamino-6-isopropyl-amino-s-triazine）has been detected in ground water in several areas of the United States for many years,as well as in China,wherein the growth rate of its gross

Is it necessary to stop glucagon-like peptide-1 receptor agonists prior to endoscopic procedure? A retrospective study

BACKGROUND Glucagon-like peptide-1 receptor agonists(GLP-1 RA)are effective in diabetes and obesity,reducing hyperglycemia by increasing insulin release and delaying gastric emptying.However,they can cause gastroparesis,raising concerns about aspiration during procedures.Recent guidelines advise discontinuing GLP-1 RA before surgery to reduce the risk of pulmonary aspiration.AIM To evaluate the effect of GLP-1 RAs on gastric residual contents during endosco-pic procedures.METHODS A retrospective chart review at BronxCare Health System,New York,from January 2019 to October 2023,assessed gastric residue and aspiration in GLP-1 RA patients undergoing endoscopic procedures.Two groups were compared based on dietary status before the procedure.Data included demographics,symptoms of gastroparesis,opiate use,hemoglobin A1c,GLP-1 agonist indication,endo-scopic details,and aspiration occurrence.IBM SPSS was used for analysis,cal-culating means,standard deviations,and applying Pearson’s chi-square and t-tests for associations,with P<0.05 as being significant.RESULTS During the study,306 patients were included,with 41.2%on a clear liquid/low residue diet and 58.8%on a regular diet before endoscopy.Most patients(63.1%)were male,with a mean age of 60±12 years.The majority(85.6%)were on GLP-1 RAs for diabetes,and 10.1%reported digestive symptoms before endoscopy.Among those on a clear liquid diet,1.5%had residual food at endoscopy compared to 10%on a regular diet,which was statistically significant(P=0.03).Out of 31 patients with digestive symptoms,13%had residual food,all from the regular diet group(P=0.130).No complications were reported during or after the procedures.CONCLUSION The study reflects a significant rise in GLP-1 RA use for diabetes and obesity.A 24-hour liquid diet seems safe for endoscopic procedures without aspiration.Patients with upper gastrointestinal symptoms might have a higher residual food risk,though not statistically significant.Further research is needed to assess risks based on diabetes duration,gastroparesis,and GLP-1 RA dosing,aiming to minimize interruptions in therapy during procedures.

Identification of various food residuals on denim based on hyperspectral imaging system and combination optimal strategy

As the science and technology develop,crime methods and scenes have become increasingly complex and diverse.Trace evidence analysis has become amore and more important criminal investigation technology and liquid is the main form of trace evidence.Food can provide not only energy,but clues to solve crimes.In this study,we build a hyperspectral imaging system to detect liquid residue traces,including apple juice,coffee,cola,milk and tea,on denims with light,middle and dark colors.The obtained hyperspectral images are first subjected to spectral calibration and hyperspectral data pretreatment.Subsequently,Partial Least Squares(PLS)is applied to select the informative wavelengths from the preprocessed spectra.For modeling phase,the combination optimal strategy,support vector machine(SVM)combined with random forest(RF),is developed to establish classification models.The experimental results demonstrate that the combination optimal model can achieve TPR,FPR,Precision,Recall,F1,and AUC of 83.5%,2.30%,79.7%,83.5%,81.6%,and 94.7%for classifying fabrics contaminated by various food residuals.With respect to the classification of liquid and fabric types,the combination optimalmodel also yields satisfactory classification performance.In future work,wewill expand the types of liquid,and make appropriate adjustment to algorithms for improving the robustness of classification models.This research may play a positive role in the construction of a harmonious society.