期刊文献+
共找到1,487篇文章
< 1 2 75 >
每页显示 20 50 100
Idioms,Collocations,Formulaic Phrases and Second Language Acquisition 被引量:1
1
作者 李胜玉 《Sino-US English Teaching》 2020年第8期235-238,共4页
Idioms,collocations,and formulaic phrases are three factors playing the important role in the second language acquisition(SLA).This essay firstly deals with the definitions of these concepts,then it illustrates the im... Idioms,collocations,and formulaic phrases are three factors playing the important role in the second language acquisition(SLA).This essay firstly deals with the definitions of these concepts,then it illustrates the importance of them to SLA on two perspectives—idioms,collocations,and formulaic phrases respectively and they regarded as a whole.Therefore,in this way,the essay may lead to the answer the question“How are idioms,collocations,and formulaic phrases important to SLA?” 展开更多
关键词 IDIOMS COLLOCATIONS formulaic phrases second language acquisition
下载PDF
Formulaic Language in Spoken EFL Teaching
2
作者 Yi Wang 《Journal of Contemporary Educational Research》 2020年第10期73-75,共3页
This paper discusses the role of formulaic language in the teaching of English as a foreign language,and in particular in the decoding of the spoken production of native speakers(NSs).
关键词 formulaic language Spoken English Native speech Tone language PROSODY Speaking speed
下载PDF
Formulaic Language in Second Language Acquisition:A Review
3
作者 喻霞 《海外英语》 2015年第2期198-201,共4页
This paper argues for the need of the reappraisal of the formulaic aspect of language in second language acquisition by drawing insights from recent development in applied linguistics, psycholinguistics and corpus lin... This paper argues for the need of the reappraisal of the formulaic aspect of language in second language acquisition by drawing insights from recent development in applied linguistics, psycholinguistics and corpus linguistics. This library study begins by reviewing the dual-nature view of language in relation to formulaic aspect of language. Then, a brief survey of evidence from corpus linguistics is provided to demonstrate the formulaicity of language. What follows is the discussion of rehearsal and implicit learning vis-a-vis memory from the perspective of psycholinguistics. After that, the role of formulaic language in second language acquisition is examined by taking stock of empirical findings that have accumulated in this area. Finally, by way of conclusion, how the formulaicity of language can shed light on second/foreign language teaching theory is illustrated. 展开更多
关键词 formulaic LANGUAGE SECOND LANGUAGE ACQUISITION CORPUS LINGUISTICS PSYCHOLINGUISTICS memory
下载PDF
The Role of Formulaic Speech in SLA Learner’s Spoken Language Performance
4
作者 毛启红 《林区教学》 2008年第4期72-74,共3页
A controversial issue in the field of Second Language spoken English acquisition is which one plays a more important role, the formulaic speech or the creative rules? And researchers have long kept different opinions ... A controversial issue in the field of Second Language spoken English acquisition is which one plays a more important role, the formulaic speech or the creative rules? And researchers have long kept different opinions about the definition of formulaic speech. The present paper discusses the definition of formulaic speech, describes relevant empirical studies and summarizes some roles of formulaic speech from our own experiments, hoping to provide some insights for second language spoken English teaching and learning. 展开更多
关键词 formulaic SPEECH SPOKEN English acquisition LEXICAL PHRASES
下载PDF
Formulaic Sequences in L1 and Advanced L2 Chinese Learners' Writing
5
作者 张凯程 《海外英语》 2020年第10期95-97,共3页
This corpus-based study cmploys statistical analysis to compare the use of non-compositional formulaic sequences by high proficiency Chinese learners and native students.The top 5 overused and underused patterns by Ch... This corpus-based study cmploys statistical analysis to compare the use of non-compositional formulaic sequences by high proficiency Chinese learners and native students.The top 5 overused and underused patterns by Chinese users are identified.Features of their usage point to a lack of register awareness as well as linguistic resources,while showing individual differences. 展开更多
关键词 formulaic sequences learner corpora Contrastive Interlanguage Analysis(CIA) corpus linguistics English Language Teaching(ELT)
下载PDF
Analytical Solution and Simplified Formula for Added Mass of Horizontal and Vertical Motions of Truncated Cylinders Under Earthquake Action
6
作者 WANG Pi-guang LYU Si-yu +2 位作者 QU Yang ZHAO Mi DU Xiu-li 《China Ocean Engineering》 SCIE EI CSCD 2024年第1期54-67,共14页
This paper investigates the hydrodynamic characteristics of floating truncated cylinders undergoing horizontal and vertical motions due to earthquake excitations in the finite water depth.The governing equation of the... This paper investigates the hydrodynamic characteristics of floating truncated cylinders undergoing horizontal and vertical motions due to earthquake excitations in the finite water depth.The governing equation of the hydrodynamic pressure acting on the cylinder is derived based on the radiation theory with the inviscid and incompressible assumptions.The governing equation is solved by using the method of separating variables and analytical solutions are obtained by assigning reasonable boundary conditions.The analytical result is validated by a numerical model using the exact artificial boundary simulation of the infinite water.The main variation and distribution characteristics of the hydrodynamic pressure acting on the side and bottom of the cylinder are analyzed for different combinations of wide-height and immersion ratios.The added mass coefficient of the cylinder is calculated by integrating the hydrodynamic pressure and simplified formulas are proposed for engineering applications.The calculation results show that the simplified formulas are in good agreement with the analytical solutions. 展开更多
关键词 EARTHQUAKE hydrodynamic pressure truncated cylinder added mass simplified formula
下载PDF
CAUCHY TYPE INTEGRALS AND A BOUNDARY VALUE PROBLEM IN A COMPLEX CLIFFORD ANALYSIS
7
作者 曹南斌 李尊凤 +1 位作者 杨贺菊 乔玉英 《Acta Mathematica Scientia》 SCIE CSCD 2024年第1期369-385,共17页
Clifford analysis is an important branch of modern analysis;it has a very important theoretical significance and application value,and its conclusions can be applied to the Maxwell equation,Yang-Mill field theory,quan... Clifford analysis is an important branch of modern analysis;it has a very important theoretical significance and application value,and its conclusions can be applied to the Maxwell equation,Yang-Mill field theory,quantum mechanics and value problems.In this paper,we first give the definition of a quasi-Cauchy type integral in complex Clifford analysis,and get the Plemelj formula for it.Second,we discuss the H?lder continuity for the Cauchy-type integral operators with values in a complex Clifford algebra.Finally,we prove the existence of solutions for a class of linear boundary value problems and give the integral representation for the solution. 展开更多
关键词 Clifford analysis Cauchy type integral Plemelj formula Holder continuous boundary value problems
下载PDF
Examining the Use of Scott’s Formula and Link Expiration Time Metric for Vehicular Clustering
8
作者 Fady Samann Shavan Askar 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第3期2421-2444,共24页
Implementing machine learning algorithms in the non-conducive environment of the vehicular network requires some adaptations due to the high computational complexity of these algorithms.K-clustering algorithms are sim... Implementing machine learning algorithms in the non-conducive environment of the vehicular network requires some adaptations due to the high computational complexity of these algorithms.K-clustering algorithms are simplistic,with fast performance and relative accuracy.However,their implementation depends on the initial selection of clusters number(K),the initial clusters’centers,and the clustering metric.This paper investigated using Scott’s histogram formula to estimate the K number and the Link Expiration Time(LET)as a clustering metric.Realistic traffic flows were considered for three maps,namely Highway,Traffic Light junction,and Roundabout junction,to study the effect of road layout on estimating the K number.A fast version of the PAM algorithm was used for clustering with a modification to reduce time complexity.The Affinity propagation algorithm sets the baseline for the estimated K number,and the Medoid Silhouette method is used to quantify the clustering.OMNET++,Veins,and SUMO were used to simulate the traffic,while the related algorithms were implemented in Python.The Scott’s formula estimation of the K number only matched the baseline when the road layout was simple.Moreover,the clustering algorithm required one iteration on average to converge when used with LET. 展开更多
关键词 CLUSTERING vehicular network Scott’s formula FastPAM
下载PDF
Trace formula of the integro-differential operator on a quantum graph
9
作者 WEI Li-xiao YANG Chuan-fu 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第2期311-318,共8页
In this paper we study the eigenvalue problem for integro-differential operators on a lasso graph.The trace formula of the operator is established by applying the residual technique in complex analysis.
关键词 integro-differential operators EIGENVALUE trace formula
下载PDF
Locally and globally uniform approximations for ruin probabilities of a nonstandard bidimensional risk model with subexponential claims
10
作者 LIU Zai-ming GENG Bing-zhen WANG Shi-jie 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第1期98-113,共16页
Consider a nonstandard continuous-time bidimensional risk model with constant force of interest,in which the two classes of claims with subexponential distributions satisfy a general dependence structure and each pair... Consider a nonstandard continuous-time bidimensional risk model with constant force of interest,in which the two classes of claims with subexponential distributions satisfy a general dependence structure and each pair of the claim-inter-arrival times is arbitrarily dependent.Under some mild conditions,we achieve a locally uniform approximation of the finite-time ruin probability for all time horizon within a finite interval.If we further assume that each pair of the claim-inter-arrival times is negative quadrant dependent and the two classes of claims are consistently-varying-tailed,it shows that the above obtained approximation is also globally uniform for all time horizon within an infinite interval. 展开更多
关键词 bidimensional risk model asymptotic formula subexponential distribution consistently varying tail ruin probability
下载PDF
Uncertainty and sensitivity analysis of in-vessel phenomena under severe accident mitigation strategy based on ISAA-SAUP program
11
作者 Hao Yang Ji-Shen Li +2 位作者 Zhi-Ran Zhang Bin Zhang Jian-Qiang Shan 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第1期108-123,共16页
The phenomenology involved in severe accidents in nuclear reactors is highly complex.Currently,integrated analysis programs used for severe accident analysis heavily rely on custom empirical parameters,which introduce... The phenomenology involved in severe accidents in nuclear reactors is highly complex.Currently,integrated analysis programs used for severe accident analysis heavily rely on custom empirical parameters,which introduce considerable uncertainty.Therefore,in recent years,the field of severe accidents has shifted its focus toward applying uncertainty analysis methods to quantify uncertainty in safety assessment programs,known as“best estimate plus uncertainty(BEPU).”This approach aids in enhancing our comprehension of these programs and their further development and improvement.This study concentrates on a third-generation pressurized water reactor equipped with advanced active and passive mitigation strategies.Through an Integrated Severe Accident Analysis Program(ISAA),numerical modeling and uncertainty analysis were conducted on severe accidents resulting from large break loss of coolant accidents.Seventeen uncertainty parameters of the ISAA program were meticulously screened.Using Wilks'formula,the developed uncertainty program code,SAUP,was employed to carry out Latin hypercube sampling,while ISAA was employed to execute batch calculations.Statistical analysis was then conducted on two figures of merit,namely hydrogen generation and the release of fission products within the pressure vessel.Uncertainty calculations revealed that hydrogen production and the fraction of fission product released exhibited a normal distribution,ranging from 182.784 to 330.664 kg and from 15.6 to 84.3%,respectively.The ratio of hydrogen production to reactor thermal power fell within the range of 0.0578–0.105.A sensitivity analysis was performed for uncertain input parameters,revealing significant correlations between the failure temperature of the cladding oxide layer,maximum melt flow rate,size of the particulate debris,and porosity of the debris with both hydrogen generation and the release of fission products. 展开更多
关键词 Gen-III PWR Severe accident mitigation Wilks’formula HYDROGEN Fission products Uncertainty and sensitivity analysis
下载PDF
Double casing warhead with sandwiched charge:The axial distribution of fragments velocities
12
作者 Ping Ye Yongxiang Dong +5 位作者 Qitian Sun Peizhuo Shi Wang Yao Yongnan Li Yujing Li Mingze Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期201-216,共16页
The double casing warhead with sandwiched charge is a novel fragmentation warhead that can produce two groups of fragments with different velocity,and the previous work has presented a calculation formula to determine... The double casing warhead with sandwiched charge is a novel fragmentation warhead that can produce two groups of fragments with different velocity,and the previous work has presented a calculation formula to determine the maximum fragment velocity.The current work builds on the published formula to further develop a formula for calculating the axial distribution characteristics of the fragment velocity.For this type of warhead,the simulation of the dispersion characteristics of the detonation products at different positions shows that the detonation products at the ends have a much larger axial velocity than those in the middle,and the detonation products have a greater axial dispersion velocity when they are closer to the central axis.The loading process and the fragment velocity vary with the axial position for both casing layers,and the total velocity of the fragments is the vector sum of the radial velocity and the axial velocity.At the same axial position,the acceleration time of the inner casing is greater than that of the outer casing.For the same casing,the fragments generated at the ends have a longer acceleration time than the fragments from the middle.The proposed formula is validated with the X-ray radiography results of the four warheads previously tested experimentally and the 3D smoothedparticle hydrodynamics numerical simulation results of several series of new warheads with different configurations.The formula can accurately and reliably calculate the fragment velocity when the lengthto-diameter ratio of the charge is greater than 1.5 and the thickness of the casing is less than 20%its inner radius.This work thus provides a key reference for the theoretical analysis and the design of warheads with multiple casings. 展开更多
关键词 Double casing warhead Sandwiched charge Fragment velocity Rarefaction wave Gurney formula Explosive loading
下载PDF
Jianpi Qinghua Formula Alleviates Diabetic Myocardial Injury Through Inhibiting JunB/c-Fos Expression
13
作者 Lin WANG Qing-guang CHEN Hao LU 《Current Medical Science》 SCIE CAS 2024年第1期144-155,共12页
Objective Diabetic cardiomyopathy(DCM)represents a substantial risk factor for heart failure and increased mortality in individuals afflicted with diabetes mellitus(DM).DCM typically manifests as myocardial fibrosis,m... Objective Diabetic cardiomyopathy(DCM)represents a substantial risk factor for heart failure and increased mortality in individuals afflicted with diabetes mellitus(DM).DCM typically manifests as myocardial fibrosis,myocardial hypertrophy,and impaired left ventricular diastolic function.While the clinical utility of the Jianpi Qinghua(JPQH)formula has been established in treating diabetes and insulin resistance,its potential efficacy in alleviating diabetic cardiomyopathy remains uncertain.This study aims to investigate the impact and underlying molecular mechanisms of the JPQH formula(JPQHF)in ameliorating myocardial injury in nonobese diabetic rats,specifically focusing on apoptosis and inflammation.Methods Wistar rats were assigned as the normal control group(CON),while Goto-Kakizaki(GK)rats were randomly divided into three groups:DM,DM treated with the JPQHF,and DM treated with metformin(MET).Following a 4-week treatment regimen,various biochemical markers related to glucose metabolism,cardiac function,cardiac morphology,and myocardial ultrastructure in GK rats were assessed.RNA sequencing was utilized to analyze differential gene expression and identify potential therapeutic targets.In vitro experiments involved high glucose to induce apoptosis and inflammation in H9c2 cells.Cell viability was evaluated using CCK-8 assay,apoptosis was monitored via flow cytometry,and the production of inflammatory cytokines was measured using quantitative real-time PCR(qPCR)and ELISA.Protein expression levels were determined by Western blotting analysis.The investigation also incorporated the use of MAPK inhibitors to further elucidate the mechanism at both the transcriptional and protein levels.Results The JPQHF group exhibited significant reductions in interventricular septal thickness at end-systole(IVSs)and left ventricular internal diameter at end-systole and end-diastole(LVIDs and LVIDd).JPQHF effectively suppressed high glucose-induced activation of IL-1βand caspase 3 in cardiomyocytes.Furthermore,JPQHF downregulated the expression of myocardial JunB/c-Fos,which was upregulated in both diabetic rats and high glucose-treated H9c2 cells.Conclusion The JPQH formula holds promise in mitigating diabetic myocardial apoptosis and inflammation in cardiomyocytes by inhibiting JunB/c-Fos expression through suppressing the MAPK(p38 and ERK1/2)pathway. 展开更多
关键词 Jianpi Qinghua formula diabetic cardiomyopathy AP-1 transcription factor apoptosis inflammation
下载PDF
A polarization sensitive interferometer:Delta interferometer
14
作者 卫超奇 刘建彬 +7 位作者 董翼飞 孙雨农 周宇 郑淮斌 刘严严 闫秀生 李福利 徐卓 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期369-377,共9页
A new type of polarization sensitive interferometer is proposed,named the Delta interferometer,inspired by its geometry resembling the Greek letter Delta.The main difference between the Delta interferometer and other ... A new type of polarization sensitive interferometer is proposed,named the Delta interferometer,inspired by its geometry resembling the Greek letter Delta.The main difference between the Delta interferometer and other existing interferometers,such as Michelson,Mach-Zehnder and Young's double-slit interferometers,is that the two interfering paths are asymmetrical in the Delta interferometer.The visibility of the first-order interference pattern observed in the Delta interferometer is dependent on the polarization of the incidental light.Optical coherence theory is employed to interpret this phenomenon and single-mode continuous-wave laser light is employed to verify the theoretical predictions.The theoretical and experimental results are consistent.The Delta interferometer is a perfect tool to study the reflection of electromagnetic fields in different polarizations and may find applications in polarization-sensitive scenarios. 展开更多
关键词 phase sensitive interferometer Fresnel formula first-order interference
下载PDF
Saturation Estimation with Complex Electrical Conductivity for Hydrate-Bearing Clayey Sediments:An Experimental Study
15
作者 XING Lanchang ZHANG Shuli +8 位作者 ZHANG Huanhuan WU Chenyutong WANG Bin LAO Liyun WEI Wei HAN Weifeng WEI Zhoutuo GE Xinmin DENG Shaogui 《Journal of Ocean University of China》 CAS CSCD 2024年第1期173-189,共17页
Clays have considerable influence on the electrical properties of hydrate-bearing sediments.It is desirable to understand the electrical properties of hydrate-bearing clayey sediments and to build hydrate saturation(S... Clays have considerable influence on the electrical properties of hydrate-bearing sediments.It is desirable to understand the electrical properties of hydrate-bearing clayey sediments and to build hydrate saturation(S_(h))models for reservoir evaluation and monitoring.The electrical properties of tetrahydrofuran-hydrate-bearing sediments with montmorillonite are characterized by complex conductivity at frequencies from 0.01 Hz to 1 kHz.The effects of clay and Sh on the complex conductivity were analyzed.A decrease and increase in electrical conductance result from the clay-swelling-induced blockage and ion migration in the electrical double layer(EDL),respectively.The quadrature conductivity increases with the clay content up to 10%because of the increased surface site density of counterions in EDL.Both the in-phase conductivity and quadrature conductivity decrease consistently with increasing Sh from 0.50 to 0.90.Three sets of models for Sh evaluation were developed.The model based on the Simandoux equation outperforms Archie’s formula,with a root-mean-square error(E_(RMS))of 1.8%and 3.9%,respectively,highlighting the clay effects on the in-phase conductivity.The fre-quency effect correlations based on in-phase and quadrature conductivities exhibit inferior performance(E_(RMS)=11.6%and 13.2%,re-spectively)due to the challenge of choosing an appropriate pair of frequencies and intrinsic uncertainties from two measurements.The second-order Cole-Cole formula can be used to fit the complex-conductivity spectra.One pair of inverted Cole-Cole parameters,i.e.,characteristic time and chargeability,is employed to predict S_(h) with an E_(RMS) of 5.05%and 9.05%,respectively. 展开更多
关键词 gas hydrate complex electrical conductivity hydrate-bearing clayey sediment hydrate saturation Simandoux equation frequency dispersion Cole-Cole formula
下载PDF
Antidepressant effects of Peiyuan Jieyu formula in a mouse model of chronic stress in conjunction with lipopolysaccharide-induced depression
16
作者 Qin Tang Yu Li +3 位作者 Tao Yang Xiaoxu Fan Lina Li Hongsheng Chang 《Journal of Traditional Chinese Medical Sciences》 CAS 2024年第1期111-119,共9页
Objective:To explore the mechanism of the Peiyuan Jieyu formula in treating depression by assessing its impact on a lipopolysaccharide-induced(LPS-induced)depression mouse model.Methods:We created a mouse model of dep... Objective:To explore the mechanism of the Peiyuan Jieyu formula in treating depression by assessing its impact on a lipopolysaccharide-induced(LPS-induced)depression mouse model.Methods:We created a mouse model of depression by exposing mice that had previously received chronic stress to intraperitoneal LPS injections.The mice were divided into the following groups:control,model,fluoxetine,Tiansi Yin,Sini powder,and low-,medium-,and high-dose Peiyuan Jieyu formula groups.Forced swim and tail suspension tests were used to assess the efficacy of the depression(despair)model,and weight gain rates were also measured.Furthermore,serum levels of various depression and inflammation-associated molecules,including tumor necrosis factor-a(TNF-a),interferon-γ(IFN-γ),tryptophan,5-hydroxytryptamine,kynurenine(KYN),and kynurenic acid(KA)were assessed.Furthermore,the expression levels of ionic calcium-binding adaptor molecule-1(IBA-1)and indoleamine 2,3-dioxygenase(IDO)mRNA in hippocampal microglia were measured.Results:The model group displayed greater despair-associated immobility,which was shortened in response to various doses of Peiyuan Jieyu formula.Furthermore,formula administration significantly reduced serum TNF-a levels and hippocampal IDO mRNA expression.The high formula dose also reduced IFN-γand IBA-1 levels,the latter was also decreased in response to the medium formula dose.However,the low formula dose reduced serum KYN level and KYN/tryptophan(TRP)and KYN/KA ratios.Conclusion:The Peiyuan Jieyu formula holds immense potential in treating depression in a mouse model,potentially inhibiting inflammation and improving TRP-KYN metabolic disorders. 展开更多
关键词 Peiyuan Jieyu formula DEPRESSION Chronic stress LIPOPOLYSACCHARIDE Inflammation Tryptophan pathway
下载PDF
Evaluation of the famous classic formula Sanhua decoction based on network pharmacology and multi-component quantitative analysis
17
作者 Xin Zhang Wan-Cui Wang +6 位作者 Jin-Kui Zhang Wei-Mei Zhang Peng-Wang Wang Peng-Cheng Lin Yong-Chang Lu Xia Li Wen-Yuan Gao 《Traditional Medicine Research》 2024年第1期1-13,共13页
Background:Sanhua decoction has significant effects in the treatment of stroke.The study of the Sanhua decoction material benchmark was carried out to analyze the value transfer relationship between the Chinese herbal... Background:Sanhua decoction has significant effects in the treatment of stroke.The study of the Sanhua decoction material benchmark was carried out to analyze the value transfer relationship between the Chinese herbal pieces and the substance benchmark.Methods:Network pharmacology was employed to investigate the potential active components and molecular mechanisms of Sanhua decoction in the treatment of stroke.15 batches of Sanhua decoction lyophilized powder were prepared using traditional formulas and subjected to high-performance liquid chromatography analysis to generate fingerprints of the Sanhua decoction substance benchmarks.Then,a multi-component quantitative analysis method was established,allowing for the simultaneous determination of ten components,to study the transfer of quantity values between pieces and substance benchmarks.Results:60 active ingredients were screened from Sanhua decoction by network pharmacology,of which gallic acid,magnolol honokiol,physcion,and aloe-emodin may have a greater effect than other active components.63 key targets and 134 pathways were predicted as the potential mechanism of Sanhua decoction in treating stroke.The fingerprint similarity of the Sanhua decoction substance benchmarks was found to be good among the 15 batches,confirming the 19 common peaks.The content of the 10 components was basically consistent.The components’transfer rates were within 30%of their respective means.Conclusions:This study provided a comprehensive and reliable strategy for the quality evaluation of Sanhua decoction substance benchmarks and held significant importance in improving its application value. 展开更多
关键词 Sanhua decoction classic famous formula HPLC fingerprinting value transfer network pharmacology
下载PDF
Jianqu,a traditional Chinese medicine,alleviates functional dyspepsia in high-calorie and high-protein diet mice
18
作者 Jing-Yan Yang Xiao-Xing Li +7 位作者 Juan Chen Yan-Jun Liu Yue-Hong Wu Ning-Yu Luo Cai-Xia Yang Yang Li Si-Jing Liu Jin-Lin Guo 《Traditional Medicine Research》 2024年第6期42-54,共13页
Background:Jianqu has been used to alleviate symptoms in patients with functional dyspepsia,but its specific anti-functional dyspepsia effect is still unclear.Therefore,our study aimed to investigate the impact of Jia... Background:Jianqu has been used to alleviate symptoms in patients with functional dyspepsia,but its specific anti-functional dyspepsia effect is still unclear.Therefore,our study aimed to investigate the impact of Jianqu on functional dyspepsia in mice.Methods:The phytochemical profile of Jianqu was analyzed by UPLC-Q-TOF-MS.Subsequently,Kunming mice were fed a high-calorie or high-protein diet(HCHP)for 7 days,and then orally treated with vehicle or Jianqu(1.62 g/kg body weight(b.w.)and 3.25 g/kg b.w.)for 10 days.A carbon powder solution was used to detect the gastric emptying and intestinal transit rate.The pathological changes in stomach and duodenum were evaluated by hematoxylin-eosin staining.The occludin,claudin-1,ZO-1 and CD45 expression was measured by immunocytochemical staining.Importantly,the serum gastrointestinal hormones were detected by ELISA.In addition,the gut microbiota composition was determined using 16S rRNA gene sequencing.The cecal short chain fatty acids were assessed by gas chromatography.Results:In general,17 phytochemical compounds were identified from Jianqu,which significantly improved the gastric emptying rate and intestinal transit rate(p<0.01),increased the body weight and food intake(p<0.0001)in HCHP mice as well.Though HCHP did not cause significant pathological lesions in the gastrointestinal tract,increased the expression of CD45 in the duodenum(p<0.05)was observed.Notably,Jianqu attenuated this abnormal expression of CD45(p<0.05).The levels of serum gastrointestinal hormones were significantly normalized by Jianqu intervention(p<0.05).Moreover,Jianqu increased the relative abundance of Roseburia as well as short chain fatty acids levels in cecum(p<0.05).Conclusion:The present results showed that Jianqu alleviated dyspeptic symptoms in HCHP mice possibly through reducing the duodenal leukocyte infiltration,and regulating the expression of gastrointestinal hormones.These effects may be partly related to the increasing cecal short chain fatty acids levels probably via gut microbial modulation. 展开更多
关键词 herbal formula DYSPEPSIA gastrointestinal hormones gastric emptying intestinal transit
下载PDF
Effect of Luhong formula on the cardiac rehabilitation of patients with chronic heart failure
19
作者 Ji-Jie Xu Jian Dai +3 位作者 Qi-Hai Xie Pei-Chao Du Cha Li Hua Zhou 《World Journal of Clinical Cases》 SCIE 2024年第17期3027-3034,共8页
BACKGROUND Current treatments for chronic heart failure(CHF)are therapeutically ineffective.The optimization of treatments for this disease needs to be explored and analyzed.AIM To analyze the effect of using Luhong F... BACKGROUND Current treatments for chronic heart failure(CHF)are therapeutically ineffective.The optimization of treatments for this disease needs to be explored and analyzed.AIM To analyze the effect of using Luhong Formula in the cardiac rehabilitation of patients with CHF and its influence on cardiopulmonary function(CPF)and prognosis.METHODS In total,160 patients with CHF admitted between June 2022 and June 2023 were selected,including 75 receiving perindopril(control group)and 85 receiving Luhong Formula(research group).We conducted comparative analyses on the curative effects of traditional Chinese medicine(TCM)syndromes and cardiac function,CPF[oxygen consumption at the anaerobic threshold(VO2 AT)and at peak exercise(peak VO2)],echocardiographic indexes[left atrial volume index(LAVI),left ventricular muscle mass index(LVMI),left ventricular ejection fraction(LVEF)],and prognosis[major adverse cardiovascular events(MACEs)at 6 months follow-up].RESULTS The research group showed markedly higher curative effects of TCM syndromes and cardiac function than the control group.In addition,post-treatment VO2 AT,peak VO2,LVMI and LVEF in the research group were significantly higher,whereas LAVI was significantly lower,than those of the control group.Furthermore,fewer patients in the research group developed MACEs at the 6-month follow-up.CONCLUSION Luhong Formula is more therapeutically effective than perindopril for the cardiac rehabilitation of patients with CHF,specifically in enhancing CPF and prognosis. 展开更多
关键词 Luhong formula Chronic heart failure Cardiopulmonary function Cardiac rehabilitation PROGNOSIS
下载PDF
The tangential k-Cauchy-Fueter type operator and Penrose type integral formula on the generalized complex Heisenberg group
20
作者 REN Guang-zhen SHI Yun KANG Qian-qian 《Applied Mathematics(A Journal of Chinese Universities)》 SCIE CSCD 2024年第1期181-190,共10页
The tangential k-Cauchy-Fueter operator and k-CF functions are counterparts of the tangential Cauchy–Riemann operator and CR functions on the Heisenberg group in the theory of several complex variables,respectively.I... The tangential k-Cauchy-Fueter operator and k-CF functions are counterparts of the tangential Cauchy–Riemann operator and CR functions on the Heisenberg group in the theory of several complex variables,respectively.In this paper,we introduce a Lie group that the Heisenberg group can be imbedded into and call it generalized complex Heisenberg.We investigate quaternionic analysis on the generalized complex Heisenberg.We also give the Penrose integral formula for k-CF functions and construct the tangential k-Cauchy-Fueter complex. 展开更多
关键词 the generalized complex Heisenberg group the tangential k-Cauchy-Fueter type operator Penrose-type integral formula
下载PDF
上一页 1 2 75 下一页 到第
使用帮助 返回顶部