Association between Free Triiodothyronine Levels and Peripheral Arterial Disease in Euthyroid Participants

This current cross-sectional study investigates the relationship between thyroid hormones and peripheral artery disease （PAD） among euthyroid Chinese population aged 40 years and above. Serum free triiodothyronine （FT3）, free thyroxin （FT4）, thyroid-stimulating hormone （TSH）, and thyroid antibodies were measured.

Using a Collateral Damage Model to Explain Survival Data in West Nile Virus Infections

Simulation code for a model of the adaptive immune response seen in flavivirus infections is used to explain the immunopathological consequences seen in West Nile Virus virus (WNV) infections. We use a model that specifically handles the differences in how the virus infects resting cells, the G0 state, versus dividing cells, the G1 state, which includes vastly increased MHC-I upregulation for resting cells over dividing cells. The simulation suggests how the infection progresses in a one host model and the results shed insight into the unusual survival curve data obtained for this infection: there is an increase in health even though viral load has increased.

EFFECTS OF GINSENOSIDE Rb1 AND Rg1 ON SYNAPTOSOMAL FREE CALCIUM LEVEL, ATPase AND CALMODULIN IN RAT HIPPOCAMPUS

Calcium homeostasis in synaptosomes is altered during aging. The intrasynaptomal free calcium concentration ([Ca2+]i) was determined in 3- and 24-month-old rats treated with or without Rbl and Rgl. As expected, the [Ca2-]i level increased with age. Treatment with Rbl and Rgl elicited an obvious decrease of [Ca2+]i content, especially in aged rates. In addition, Rbl and Rgl significantly stimulated the activity of Na+, K+-ATPase while Rbl inhibited the activity of Ca2+, Mg2--ATPase arid calmodulin. In view of the close relationship of [Ca2-]i level with aging, the changes of [Ca2+]i induced by Rbl and Rgl, as shown by our results, might provide an explanation of the mechanisms of their antiaging function.

Transition Gibbs free energy level cross section and formulation of carrier SRH recombination rate

The transition among multiple charging states of a semiconductor＇s localized intrinsic/impurity defects is considered as phase transitions, and the concept of transition Gibbs free energy level （TGFEL） is proposed. Dependence of the cross section of TGFEL on its charge state is discussed. Introduction of TGFEL to replace acti- vation energy has fundamentally important consequences for semiconductor physics and devices. TGFEL involves entropy. What is to be included and not included in the entropy term consistently for all defect levels is an unre- solved open question, related to correct interpretation of various experimental data associated with various defect levels. This work is a first step towards resolving this question.

Sensitivity of Lake-Effect Convection to the Lake Surface Temperature over Poyang Lake in China

In this study, high-resolution weather research and forecasting(WRF) simulations are used to explore the sensitivity of lake-effect convection over Poyang Lake(PL) to the change of lake surface temperature(LST). A control experiment(CTR) with climate mean LST(303 K) is compared with six sensitivity experiments(CTR-1/2/3K and CTR+1/2/3K) in which the LSTs are set based on the mean LST difference of 6 K between the maximum and minimum. The results show that the CTR experiment reasonably reproduces the lake-effect convection, and the lake-effect convection in sensitivity experiments is significantly influenced by the LST. With the increase of LST, the initiation time of the lake-effect convection is advanced gradually, while the initiation location moves PL from its shore.The lake-effect convection strengthens(weakens) in the increase-temperature CTR+1/2/3K(decrease-temperature CTR-1/2/3K) experiments, but the lake-effect convection does not monotonically strengthen with the LST, for the strongest one occurring in the CTR+1K experiment. The corresponding diagnostic analysis shows that the upward sensible heat flux and latent heat flux over PL increase with the LST, resulting in the enhancement of the lake-land breeze and the enlargement of the convective available potential energy(CAPE). This is the main reason for the changes in the initiation time and location, as well as the intensity of lake-effect convection in different experiments.In addition, the non-monotonous variation of the level of free convection, which is mainly induced by the non-monotonous variation of the lifting condensation level, is responsible for the non-monotonous variation of the lake-effect convection intensity with the LST.