Objective The aim of this study is to investigate whether microwave exposure would affect the N-methyI-D-aspartate receptor (NMDAR) signaling pathway to establish whether this plays a role in synaptic plasticity imp...Objective The aim of this study is to investigate whether microwave exposure would affect the N-methyI-D-aspartate receptor (NMDAR) signaling pathway to establish whether this plays a role in synaptic plasticity impairment. Methods 48 male Wistar rats were exposed to 30 mW/cm^2 microwave for 10 min every other day for three times. Hippocampal structure was observed through H&E staining and transmission electron microscope. PC12 cells were exposed to 30 mW/cm^2 microwave for 5 min and the synapse morphology was visualized with scanning electron microscope and atomic force microscope. The release of amino acid neurotransmitters and calcium influx were detected. The expressions of several key NMDAR signaling molecules were evaluated. Results Microwave exposure caused injury in rat hippocampal structure and PC12 cells, especially the structure and quantity of synapses. The ratio of glutamic acid and gamma-aminobutyric acid neurotransmitters was increased and the intracellular calcium level was elevated in PC12 cells. A significant change in NMDAR subunits (NR1, NR2A, and NR2B) and related signaling molecules (CaZ+/calmodulin-dependent kinase II gamma and phosphorylated cAMP-response element binding protein) were examined. Conclusion 30 mW/cm^2 microwave exposure resulted in alterations of synaptic structure, amino acid neurotransmitter release and calcium influx. NMDAR signaling molecules were closely associated with impaired synaptic plasticity.展开更多
Frequency-tunable microwave signal generation is proposed and experimentally demonstrated with a dual-wavelength single-longitudinal-mode (SLM) erbium-doped fiber ring laser based on a digital Opto-DMD processor and...Frequency-tunable microwave signal generation is proposed and experimentally demonstrated with a dual-wavelength single-longitudinal-mode (SLM) erbium-doped fiber ring laser based on a digital Opto-DMD processor and four-wave mixing (FWM) in a high-nonlinear photonic crystal fiber (PCF). The high-nonlinear PCF is employed for the generation of the FWM to obtain stable and uniform dual-wavelength oscillation. Two different short passive sub-ring cavities in the main ring cavity serve as mode filters to make SLM lasing. The two lasing wavelengths are electronically selected by loading different gratings on the Opto-DMD processor controlled with a computer. The wavelength spacing can be smartly adjusted from 0.165 nm to 1.08 nm within a tuning accuracy of 0.055 nm. Two microwave signals at 17.23 GHz and 27.47 GHz are achieved. The stability of the microwave signal is discussed. The system has the ability to generate a 137.36-GHz photonic millimeter signal at room temperature.展开更多
Millimeter range signals have been widely used in biology and medicine over the 20-30 years of the last century.At this time in Ukraine have been developed and implemented treatment technologies,the main ones are mill...Millimeter range signals have been widely used in biology and medicine over the 20-30 years of the last century.At this time in Ukraine have been developed and implemented treatment technologies,the main ones are millimeter therapy(MMT),microwave resonance therapy(MRT),information-wave therapy(IWT).The features of this technologies are the use of signals in the frequency band 40-78 GHz with extremely low signal levels-10-9-10-11 W/cm2,the parameters are immanent to own communication signals of the human body.The author of the article attempts to conduct a combined analysis of hardware and software of these treatment technologies with mm-band signals.Thus the specialized equipment used for the treatment,technologies and the statistical results of its use for various diseases are considered.The problems of metrological support and measuring the weak signals of the mm range are proposed to solve by creating highly sensitive radiometric systems.The results of measurements of microwave signals of natural objects that can be used for physiotherapy and physical bodies that are in contact with or in human environment are submitted.Promising areas of the using the highly sensitive radiometric measurement equipment for research in biology and medicine are presented.展开更多
We theoretically investigate the tunable delay and advancement of microwave signals based on bichromatic electromechanically induced transparency in a three-mode circuit electromechanical system, where two nanomechani...We theoretically investigate the tunable delay and advancement of microwave signals based on bichromatic electromechanically induced transparency in a three-mode circuit electromechanical system, where two nanomechanical resonators with closely spaced frequencies are independently coupled to a common microwave cavity. In the presence of a strong microwave pump field, we obtain two transparency windows accompanied by steep phase dispersion in the transmitted microwave probe field. The width of the transparency window and the group delay of the probe field can be controlled effectively by the power of the pump field. It is shown that the maximum group delay of 0.12 ms and the advancement of0.27 ms can be obtained in the current experiments.展开更多
The paper presents the microwave signal processing method using MATLAB based on the result of microwave imaging system simulation developed using Computer Simulation Technology (CST). The simulation system contains a ...The paper presents the microwave signal processing method using MATLAB based on the result of microwave imaging system simulation developed using Computer Simulation Technology (CST). The simulation system contains a transmitting/receiving antenna, human brain and a tumor inside the brain model. The source signal, microwave signal operates from 1 to 10 GHz. The generated scattering parameters (S-parameters) are in frequency domain form. This paper describes in detail regarding the signal conversion from frequency domain to time domain through proposed Inverse Fast Fourier Transform (IFFT) method as well as the noise filtering process. Peaks detection process was performed in order to identify the time delay of the reflection points at different Y-axis展开更多
Aimed at the problem of narrow tunability and low frequency microwave signal generated by the optical method,a novel approach to stabilizing the tunable photonic microwave generated by the multi-wavelength Brillouin f...Aimed at the problem of narrow tunability and low frequency microwave signal generated by the optical method,a novel approach to stabilizing the tunable photonic microwave generated by the multi-wavelength Brillouin fiber laser is proposed and is experimentally demonstrated.A singlelongitudinal-mode Brillouin fiber laser is designed,and by using the laser,a multi-wavelength Brillouin fiber laser with more than eleven orders of Stokes wave is observed.The wavelength spacing of the adjacent Stokes wave is 0.085 nm.If the Brillouin pump power is increased,the number of Stokes wave output can be further increased.The tunable microwave signals of 10.8 and 21.6 GHz are obtained by heterodyning the Rayleigh wave and Stokes wave of the multiwavelength Brillouin fiber laser.In the experiment,by tuning the pump wavelength and temperature of the gain fiber,microwave signals at different frequencies are generated.The tunable frequency range can be further expanded by using a temperature controller with a wider adjustment range,and the generated microwave signal exhibits high stability on frequency.展开更多
Results of experimental investigation of detection (rectification) of high power X-band microwave signal in diodes of various design (semiconductor p-n-junction, point-contact, Schottky, Metal-Isolator-Metal—MIM) are...Results of experimental investigation of detection (rectification) of high power X-band microwave signal in diodes of various design (semiconductor p-n-junction, point-contact, Schottky, Metal-Isolator-Metal—MIM) are reported. The maximum of the detected direct voltage V vs. power P of microwave signal and subsequent polarity reversal, previously found in MIM diodes in the optical and microwave bands, have found to be characteristic of all investigated diodes as well. After the reversal of polarity, this dependence comes linear, and the sign of the voltage corresponds to thermoEMF. In some diodes, the hysteresis on V(P) was observed. All 5 types of V(P) of MIM diodes (have made from different pairs of metals), reported earlier, were reproduced on same p-n-junction diode by variable external DC bias. These results joined with abnormal frequency cutoff forced to suggest that there is an unknown mechanism for direct flow of charge carriers (and for generate direct current) in the high-frequency electrical field, which differs from the conventional rectification.展开更多
Photonic signal processing offers a versatile and promising toolkit for contemporary scenarios ranging from digital optical communication to analog microwave operation.Compared to its electronic counterpart,it elimina...Photonic signal processing offers a versatile and promising toolkit for contemporary scenarios ranging from digital optical communication to analog microwave operation.Compared to its electronic counterpart,it eliminates inherent bandwidth limitations and meanwhile exhibits the potential to provide unparalleled scalability and flexibility,particularly through integrated photonics.However,by far the on-chip solutions for optical signal processing are often tailored to specific tasks,which lacks versatility across diverse applications.Here,we propose a streamlined chip-level signal processing architecture that integrates different active and passive building blocks in silicon-on-insulator(SOI)platform with a compact and efficient manner.Comprehensive and in-depth analyses for the architecture are conducted at levels of device,system,and application.Accompanied by appropriate configuring schemes,the photonic circuitry supports loading and processing both analog and digital signals simultaneously.Three distinct tasks are facilitated with one single chip across several mainstream fields,spanning optical computing,microwave photonics,and optical communications.Notably,it has demonstrated competitive performance in functions like image processing,spectrum filtering,and electro-optical bandwidth equalization.Boasting high universality and a compact form factor,the proposed architecture is poised to be instrumental for next-generation functional fusion systems.展开更多
An experimental study is conducted on several retro-reflective beamforming schemes for wireless power transmission to multiple wireless power receivers(referred to herein as“targets”).The experimental results demons...An experimental study is conducted on several retro-reflective beamforming schemes for wireless power transmission to multiple wireless power receivers(referred to herein as“targets”).The experimental results demonstrate that,when multiple targets broadcast continuous-wave pilot signals at respective frequencies,a retro-reflective wireless power transmitter is capable of generating multiple wireless power beams aiming at the respective targets as long as the multiple pilot signals are explicitly separated from one another by the wireless power transmitter.However,various practical complications are identified when the pilot signals of multiple targets are not appropriately differentiated from each other by the wireless power transmitter.Specifically,when multiple pilot signals are considered to be carried by the same frequency,the wireless power transmission performance becomes heavily dependent on the interaction among the pilot signals,which is highly undesirable in practice.In conclusion,it is essential for a retro-reflective wireless power transmitter to explicitly discriminate multiple targets’pilot signals among each other.展开更多
A novel scheme for the generation of background-free pulsed microwave signals is proposed and experimentally demonstrated based on spectral shaping,frequency-to-time mapping,and balanced photodetection.In the proposed...A novel scheme for the generation of background-free pulsed microwave signals is proposed and experimentally demonstrated based on spectral shaping,frequency-to-time mapping,and balanced photodetection.In the proposed scheme,the optical spectral shaper,which consists of a differential group delay(DGD)element,two polarization controllers,and a polarization beam splitter,has two outputs with complementary power transfer functions.By passing a short optical pulse through the spectral shaper and a dispersive element(DE),a pulsed microwave signal is obtained after balanced photodetection.Thanks to the balanced photodetection,the lowfrequency components(i.e.,the background signal)in the electrical spectrum is suppressed,leading to the generation of a background-free pulsed microwave signal.Meanwhile,the spectral power of the obtained microwave signal is enhanced compared to that obtained by single-end detection.Experimental results for the generation of a pulsed microwave signal centered at 12.46 GHz show that the background signal can be suppressed by more than 30 dB,and the spectral power is increased by 5.5 dB.In addition,the central frequency of the obtained background-free pulsed microwave signal can be tuned by changing the DGD introduced by the DGD element,and/or by changing the dispersion of the DE.展开更多
Narrowband microwave generation with tuneable frequency is demonstrated by illuminating a photoconductive semiconductor switch(PCSS)with a burst-mode fibre laser.The whole system is composed of a high-power linearly p...Narrowband microwave generation with tuneable frequency is demonstrated by illuminating a photoconductive semiconductor switch(PCSS)with a burst-mode fibre laser.The whole system is composed of a high-power linearly polarized burst-mode pulsed fibre laser and a linear-state PCSS.To obtain a high-performance microwave signal,a desired envelope of burst is necessary and a pulse pre-compensation technique is adopted to avoid envelope distortion induced by the gain-saturation effect.Resulting from the technique,homogenous peak power distribution in each burst is ensured.The maximum energy of the laser burst pulse reaches 200μJ with a burst duration of 100 ns at the average power of 10 W,corresponding to a peak power of 4 kW.When the PCSS is illuminated by the burst-mode fibre laser,narrowband microwave generation with tuneable frequency(0.80-1.12 GHz)is obtained with a power up to 300 W.To the best of the authors’knowledge,it is the first demonstration of frequency-tuneable narrowband microwave generation based on a fibre laser.The high-power burst-mode fibre laser reported here has great potential for generating high-power arbitrary microwave signals for a great deal of applicable demands such as smart adaptive radar and intelligent high-power microwave systems.展开更多
基金supported by the National Natural Science Foundation of China(No.81172620)
文摘Objective The aim of this study is to investigate whether microwave exposure would affect the N-methyI-D-aspartate receptor (NMDAR) signaling pathway to establish whether this plays a role in synaptic plasticity impairment. Methods 48 male Wistar rats were exposed to 30 mW/cm^2 microwave for 10 min every other day for three times. Hippocampal structure was observed through H&E staining and transmission electron microscope. PC12 cells were exposed to 30 mW/cm^2 microwave for 5 min and the synapse morphology was visualized with scanning electron microscope and atomic force microscope. The release of amino acid neurotransmitters and calcium influx were detected. The expressions of several key NMDAR signaling molecules were evaluated. Results Microwave exposure caused injury in rat hippocampal structure and PC12 cells, especially the structure and quantity of synapses. The ratio of glutamic acid and gamma-aminobutyric acid neurotransmitters was increased and the intracellular calcium level was elevated in PC12 cells. A significant change in NMDAR subunits (NR1, NR2A, and NR2B) and related signaling molecules (CaZ+/calmodulin-dependent kinase II gamma and phosphorylated cAMP-response element binding protein) were examined. Conclusion 30 mW/cm^2 microwave exposure resulted in alterations of synaptic structure, amino acid neurotransmitter release and calcium influx. NMDAR signaling molecules were closely associated with impaired synaptic plasticity.
基金supported by the National Basic Research Program of China(Grant No.2010CB327605)the Specialized Research Fund for the Doctoral Program of Higher Education,China(Grant No.20120005120021)+2 种基金the Fundamental Research Funds for the Central Universities,China(Grant No.2013RC1202)the Program for New Century Excellent Talents in University,China(Grant No.NECT-11-0596)the Beijing Nova Program,China(Grant No.2011066)
文摘Frequency-tunable microwave signal generation is proposed and experimentally demonstrated with a dual-wavelength single-longitudinal-mode (SLM) erbium-doped fiber ring laser based on a digital Opto-DMD processor and four-wave mixing (FWM) in a high-nonlinear photonic crystal fiber (PCF). The high-nonlinear PCF is employed for the generation of the FWM to obtain stable and uniform dual-wavelength oscillation. Two different short passive sub-ring cavities in the main ring cavity serve as mode filters to make SLM lasing. The two lasing wavelengths are electronically selected by loading different gratings on the Opto-DMD processor controlled with a computer. The wavelength spacing can be smartly adjusted from 0.165 nm to 1.08 nm within a tuning accuracy of 0.055 nm. Two microwave signals at 17.23 GHz and 27.47 GHz are achieved. The stability of the microwave signal is discussed. The system has the ability to generate a 137.36-GHz photonic millimeter signal at room temperature.
文摘Millimeter range signals have been widely used in biology and medicine over the 20-30 years of the last century.At this time in Ukraine have been developed and implemented treatment technologies,the main ones are millimeter therapy(MMT),microwave resonance therapy(MRT),information-wave therapy(IWT).The features of this technologies are the use of signals in the frequency band 40-78 GHz with extremely low signal levels-10-9-10-11 W/cm2,the parameters are immanent to own communication signals of the human body.The author of the article attempts to conduct a combined analysis of hardware and software of these treatment technologies with mm-band signals.Thus the specialized equipment used for the treatment,technologies and the statistical results of its use for various diseases are considered.The problems of metrological support and measuring the weak signals of the mm range are proposed to solve by creating highly sensitive radiometric systems.The results of measurements of microwave signals of natural objects that can be used for physiotherapy and physical bodies that are in contact with or in human environment are submitted.Promising areas of the using the highly sensitive radiometric measurement equipment for research in biology and medicine are presented.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11304110 and 11174101)the Jiangsu Natural Science Foundation,China(Grant Nos.BK20130413 and BK2011411)the Natural Science Foundation of Jiangsu Higher Education Institutions of China(Grant Nos.13KJB140002and 15KJB460004)
文摘We theoretically investigate the tunable delay and advancement of microwave signals based on bichromatic electromechanically induced transparency in a three-mode circuit electromechanical system, where two nanomechanical resonators with closely spaced frequencies are independently coupled to a common microwave cavity. In the presence of a strong microwave pump field, we obtain two transparency windows accompanied by steep phase dispersion in the transmitted microwave probe field. The width of the transparency window and the group delay of the probe field can be controlled effectively by the power of the pump field. It is shown that the maximum group delay of 0.12 ms and the advancement of0.27 ms can be obtained in the current experiments.
文摘The paper presents the microwave signal processing method using MATLAB based on the result of microwave imaging system simulation developed using Computer Simulation Technology (CST). The simulation system contains a transmitting/receiving antenna, human brain and a tumor inside the brain model. The source signal, microwave signal operates from 1 to 10 GHz. The generated scattering parameters (S-parameters) are in frequency domain form. This paper describes in detail regarding the signal conversion from frequency domain to time domain through proposed Inverse Fast Fourier Transform (IFFT) method as well as the noise filtering process. Peaks detection process was performed in order to identify the time delay of the reflection points at different Y-axis
基金China Postdoctoral Science Foundation(No.2015M571637)the National Natural Science Foundation of China(No.61673108)+1 种基金the Program for Special Talent in Six Fields of Jiangsu Province(No.DZXX-028)the Industry,Education and Research Prospective Project of Jiangsu Province(No.BY2015057-39,BY2016065-03)
文摘Aimed at the problem of narrow tunability and low frequency microwave signal generated by the optical method,a novel approach to stabilizing the tunable photonic microwave generated by the multi-wavelength Brillouin fiber laser is proposed and is experimentally demonstrated.A singlelongitudinal-mode Brillouin fiber laser is designed,and by using the laser,a multi-wavelength Brillouin fiber laser with more than eleven orders of Stokes wave is observed.The wavelength spacing of the adjacent Stokes wave is 0.085 nm.If the Brillouin pump power is increased,the number of Stokes wave output can be further increased.The tunable microwave signals of 10.8 and 21.6 GHz are obtained by heterodyning the Rayleigh wave and Stokes wave of the multiwavelength Brillouin fiber laser.In the experiment,by tuning the pump wavelength and temperature of the gain fiber,microwave signals at different frequencies are generated.The tunable frequency range can be further expanded by using a temperature controller with a wider adjustment range,and the generated microwave signal exhibits high stability on frequency.
文摘Results of experimental investigation of detection (rectification) of high power X-band microwave signal in diodes of various design (semiconductor p-n-junction, point-contact, Schottky, Metal-Isolator-Metal—MIM) are reported. The maximum of the detected direct voltage V vs. power P of microwave signal and subsequent polarity reversal, previously found in MIM diodes in the optical and microwave bands, have found to be characteristic of all investigated diodes as well. After the reversal of polarity, this dependence comes linear, and the sign of the voltage corresponds to thermoEMF. In some diodes, the hysteresis on V(P) was observed. All 5 types of V(P) of MIM diodes (have made from different pairs of metals), reported earlier, were reproduced on same p-n-junction diode by variable external DC bias. These results joined with abnormal frequency cutoff forced to suggest that there is an unknown mechanism for direct flow of charge carriers (and for generate direct current) in the high-frequency electrical field, which differs from the conventional rectification.
基金supported by the National Key Research and Development Program of China(2022YFB2803700)the National Natural Science Foundation of China(62235002,62322501,12204021,62105008,62235003,and 62105260)+5 种基金Beijing Municipal Science and Technology Commission(Z221100006722003)Beijing Municipal Natural Science Foundation(Z210004)China Postdoctoral Science Foundation(2021T140004)Major Key Project of PCL,the Natural Science Basic Research Program of Shaanxi Province(2022 JQ-638)Young Talent fund of University Association for Science and Technology in Shaanxi,China(20220135)Young Talent fund of Xi'an Association for science and technology(095920221308).
文摘Photonic signal processing offers a versatile and promising toolkit for contemporary scenarios ranging from digital optical communication to analog microwave operation.Compared to its electronic counterpart,it eliminates inherent bandwidth limitations and meanwhile exhibits the potential to provide unparalleled scalability and flexibility,particularly through integrated photonics.However,by far the on-chip solutions for optical signal processing are often tailored to specific tasks,which lacks versatility across diverse applications.Here,we propose a streamlined chip-level signal processing architecture that integrates different active and passive building blocks in silicon-on-insulator(SOI)platform with a compact and efficient manner.Comprehensive and in-depth analyses for the architecture are conducted at levels of device,system,and application.Accompanied by appropriate configuring schemes,the photonic circuitry supports loading and processing both analog and digital signals simultaneously.Three distinct tasks are facilitated with one single chip across several mainstream fields,spanning optical computing,microwave photonics,and optical communications.Notably,it has demonstrated competitive performance in functions like image processing,spectrum filtering,and electro-optical bandwidth equalization.Boasting high universality and a compact form factor,the proposed architecture is poised to be instrumental for next-generation functional fusion systems.
基金supported in part by the National Natural Science Foundation of China(61871220)the Natural Science Foundation of Jiangsu Province(BK20201293)。
文摘An experimental study is conducted on several retro-reflective beamforming schemes for wireless power transmission to multiple wireless power receivers(referred to herein as“targets”).The experimental results demonstrate that,when multiple targets broadcast continuous-wave pilot signals at respective frequencies,a retro-reflective wireless power transmitter is capable of generating multiple wireless power beams aiming at the respective targets as long as the multiple pilot signals are explicitly separated from one another by the wireless power transmitter.However,various practical complications are identified when the pilot signals of multiple targets are not appropriately differentiated from each other by the wireless power transmitter.Specifically,when multiple pilot signals are considered to be carried by the same frequency,the wireless power transmission performance becomes heavily dependent on the interaction among the pilot signals,which is highly undesirable in practice.In conclusion,it is essential for a retro-reflective wireless power transmitter to explicitly discriminate multiple targets’pilot signals among each other.
基金by the National Basic Research Program of China(2012CB315705)the Open Fund of IPOC(BUPT)(IPOC2013B003)+4 种基金the Natural Science Foundation of Jiangsu Province(BK2012031)the Fundamental Research Funds for the Central Universities(NJ20140007,NE2012002,NP2013101,NS2012094)the project sponsored by SRF for ROCS,SEMthe Jiangsu Planned Projects for Postdoctoral Research Funds(1302074B)and a Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.
文摘A novel scheme for the generation of background-free pulsed microwave signals is proposed and experimentally demonstrated based on spectral shaping,frequency-to-time mapping,and balanced photodetection.In the proposed scheme,the optical spectral shaper,which consists of a differential group delay(DGD)element,two polarization controllers,and a polarization beam splitter,has two outputs with complementary power transfer functions.By passing a short optical pulse through the spectral shaper and a dispersive element(DE),a pulsed microwave signal is obtained after balanced photodetection.Thanks to the balanced photodetection,the lowfrequency components(i.e.,the background signal)in the electrical spectrum is suppressed,leading to the generation of a background-free pulsed microwave signal.Meanwhile,the spectral power of the obtained microwave signal is enhanced compared to that obtained by single-end detection.Experimental results for the generation of a pulsed microwave signal centered at 12.46 GHz show that the background signal can be suppressed by more than 30 dB,and the spectral power is increased by 5.5 dB.In addition,the central frequency of the obtained background-free pulsed microwave signal can be tuned by changing the DGD introduced by the DGD element,and/or by changing the dispersion of the DE.
文摘Narrowband microwave generation with tuneable frequency is demonstrated by illuminating a photoconductive semiconductor switch(PCSS)with a burst-mode fibre laser.The whole system is composed of a high-power linearly polarized burst-mode pulsed fibre laser and a linear-state PCSS.To obtain a high-performance microwave signal,a desired envelope of burst is necessary and a pulse pre-compensation technique is adopted to avoid envelope distortion induced by the gain-saturation effect.Resulting from the technique,homogenous peak power distribution in each burst is ensured.The maximum energy of the laser burst pulse reaches 200μJ with a burst duration of 100 ns at the average power of 10 W,corresponding to a peak power of 4 kW.When the PCSS is illuminated by the burst-mode fibre laser,narrowband microwave generation with tuneable frequency(0.80-1.12 GHz)is obtained with a power up to 300 W.To the best of the authors’knowledge,it is the first demonstration of frequency-tuneable narrowband microwave generation based on a fibre laser.The high-power burst-mode fibre laser reported here has great potential for generating high-power arbitrary microwave signals for a great deal of applicable demands such as smart adaptive radar and intelligent high-power microwave systems.