Objective： Response Evaluation Criteria in Solid Tumors （RECIST） guideline version 1.0 （RECIST 1.0） was proposed as a new guideline for evaluating tumor response and has been widely accepted as a standardized mea...Objective： Response Evaluation Criteria in Solid Tumors （RECIST） guideline version 1.0 （RECIST 1.0） was proposed as a new guideline for evaluating tumor response and has been widely accepted as a standardized measure. With a number of issues being raised on RECIST 1.0, however, a revised RECIST guideline version 1.1 （RECIST 1.1） was proposed by the RECIST Working Group in 2009. This study was conducted to compare CT tumor response based on RECIST 1.1 vs. RECIST 1.0 in patients with advanced gastric cancer （AGC）. Methods： We reviewed 61 AGC patients with measurable diseases by RECIST 1.0 who were enrolled in other clinical trials between 2008 and 2010. These patients were retrospectively re-analyzed to determine the concordance between the two response criteria using the κ statistic. Results： The number and sum of tumor diameters of the target lesions by RECIST 1.1 were significantly lower than those by RECIST 1.0 （P〈0.0001）. However, there was excellent agreement in tumor response between RECIST 1.1 and RECIST 1.0 0（κ=0.844）. The overall response rates （ORRs） according to RECIST 1.0 and RECIST 1.1 were 32.7% （20/61） and 34.5% （20/58）, respectively. One patient with partial response （PR） based on RECIST 1.0 was reclassified as stable disease （SD） by RECIST 1.1. Of two patients with SD by RECIST 1.0, one was downgraded to progressive disease and the other was upgraded to PR by RECIST 1.1. Conclusions： RECIST 1.1 provided almost perfect agreement with RECIST 1.0 in the CT assessment of tumor response of AGC.展开更多
Movies are the better source of entertainment.Every year,a great percentage of movies are released.People comment on movies in the form of reviews after watching them.Since it is difficult to read all of the reviews f...Movies are the better source of entertainment.Every year,a great percentage of movies are released.People comment on movies in the form of reviews after watching them.Since it is difficult to read all of the reviews for a movie,summarizing all of the reviews will help make this decision without wasting time in reading all of the reviews.Opinion mining also known as sentiment analysis is the process of extracting subjective information from textual data.Opinion mining involves identifying and extracting the opinions of individuals,which can be positive,neutral,or negative.The task of opinion mining also called sentiment analysis is performed to understand people’s emotions and attitudes in movie reviews.Movie reviews are an important source of opinion data because they provide insight into the general public’s opinions about a particular movie.The summary of all reviews can give a general idea about the movie.This study compares baseline techniques,Logistic Regression,Random Forest Classifier,Decision Tree,K-Nearest Neighbor,Gradient Boosting Classifier,and Passive Aggressive Classifier with Linear Support Vector Machines and Multinomial Naïve Bayes on the IMDB Dataset of 50K reviews and Sentiment Polarity Dataset Version 2.0.Before applying these classifiers,in pre-processing both datasets are cleaned,duplicate data is dropped and chat words are treated for better results.On the IMDB Dataset of 50K reviews,Linear Support Vector Machines achieve the highest accuracy of 89.48%,and after hyperparameter tuning,the Passive Aggressive Classifier achieves the highest accuracy of 90.27%,while Multinomial Nave Bayes achieves the highest accuracy of 70.69%and 71.04%after hyperparameter tuning on the Sentiment Polarity Dataset Version 2.0.This study highlights the importance of sentiment analysis as a tool for understanding the emotions and attitudes in movie reviews and predicts the performance of a movie based on the average sentiment of all the reviews.展开更多
文摘Objective： Response Evaluation Criteria in Solid Tumors （RECIST） guideline version 1.0 （RECIST 1.0） was proposed as a new guideline for evaluating tumor response and has been widely accepted as a standardized measure. With a number of issues being raised on RECIST 1.0, however, a revised RECIST guideline version 1.1 （RECIST 1.1） was proposed by the RECIST Working Group in 2009. This study was conducted to compare CT tumor response based on RECIST 1.1 vs. RECIST 1.0 in patients with advanced gastric cancer （AGC）. Methods： We reviewed 61 AGC patients with measurable diseases by RECIST 1.0 who were enrolled in other clinical trials between 2008 and 2010. These patients were retrospectively re-analyzed to determine the concordance between the two response criteria using the κ statistic. Results： The number and sum of tumor diameters of the target lesions by RECIST 1.1 were significantly lower than those by RECIST 1.0 （P〈0.0001）. However, there was excellent agreement in tumor response between RECIST 1.1 and RECIST 1.0 0（κ=0.844）. The overall response rates （ORRs） according to RECIST 1.0 and RECIST 1.1 were 32.7% （20/61） and 34.5% （20/58）, respectively. One patient with partial response （PR） based on RECIST 1.0 was reclassified as stable disease （SD） by RECIST 1.1. Of two patients with SD by RECIST 1.0, one was downgraded to progressive disease and the other was upgraded to PR by RECIST 1.1. Conclusions： RECIST 1.1 provided almost perfect agreement with RECIST 1.0 in the CT assessment of tumor response of AGC.
文摘Movies are the better source of entertainment.Every year,a great percentage of movies are released.People comment on movies in the form of reviews after watching them.Since it is difficult to read all of the reviews for a movie,summarizing all of the reviews will help make this decision without wasting time in reading all of the reviews.Opinion mining also known as sentiment analysis is the process of extracting subjective information from textual data.Opinion mining involves identifying and extracting the opinions of individuals,which can be positive,neutral,or negative.The task of opinion mining also called sentiment analysis is performed to understand people’s emotions and attitudes in movie reviews.Movie reviews are an important source of opinion data because they provide insight into the general public’s opinions about a particular movie.The summary of all reviews can give a general idea about the movie.This study compares baseline techniques,Logistic Regression,Random Forest Classifier,Decision Tree,K-Nearest Neighbor,Gradient Boosting Classifier,and Passive Aggressive Classifier with Linear Support Vector Machines and Multinomial Naïve Bayes on the IMDB Dataset of 50K reviews and Sentiment Polarity Dataset Version 2.0.Before applying these classifiers,in pre-processing both datasets are cleaned,duplicate data is dropped and chat words are treated for better results.On the IMDB Dataset of 50K reviews,Linear Support Vector Machines achieve the highest accuracy of 89.48%,and after hyperparameter tuning,the Passive Aggressive Classifier achieves the highest accuracy of 90.27%,while Multinomial Nave Bayes achieves the highest accuracy of 70.69%and 71.04%after hyperparameter tuning on the Sentiment Polarity Dataset Version 2.0.This study highlights the importance of sentiment analysis as a tool for understanding the emotions and attitudes in movie reviews and predicts the performance of a movie based on the average sentiment of all the reviews.
