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Dopamine in the prefrontal cortex plays multiple roles in the executive function of patients with Parkinson's disease 被引量:1
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作者 Zihang Zhou Yalong Yan +4 位作者 Heng Gu Ruiao Sun Zihan Liao Ke Xue Chuanxi Tang 《Neural Regeneration Research》 SCIE CAS CSCD 2024年第8期1759-1767,共9页
Parkinson’s disease can affect not only motor functions but also cognitive abilities,leading to cognitive impairment.One common issue in Parkinson’s disease with cognitive dysfunction is the difficulty in executive ... Parkinson’s disease can affect not only motor functions but also cognitive abilities,leading to cognitive impairment.One common issue in Parkinson’s disease with cognitive dysfunction is the difficulty in executive functioning.Executive functions help us plan,organize,and control our actions based on our goals.The brain area responsible for executive functions is called the prefrontal co rtex.It acts as the command center for the brain,especially when it comes to regulating executive functions.The role of the prefrontal cortex in cognitive processes is influenced by a chemical messenger called dopamine.However,little is known about how dopamine affects the cognitive functions of patients with Parkinson’s disease.In this article,the authors review the latest research on this topic.They start by looking at how the dopaminergic syste m,is alte red in Parkinson’s disease with executive dysfunction.Then,they explore how these changes in dopamine impact the synaptic structure,electrical activity,and connection components of the prefrontal cortex.The authors also summarize the relationship between Parkinson’s disease and dopamine-related cognitive issues.This information may offer valuable insights and directions for further research and improvement in the clinical treatment of cognitive impairment in Parkinson’s disease. 展开更多
关键词 DOPAMINE dopamine receptor dopamine transporter executive dysfunction neural network neural oscillation prefrontal cortex synaptic plasticity
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Bibliographical Review on Rehabilitation of Executive Functions in Patients With Developmental Coordination Disorder(DCD)
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作者 Keiko da Costa Oikawa Fabrício Bruno Cardoso +3 位作者 Filipe M.Bonone Samuel Pereira de Souza Vitor da Silva Loureiro Alfred Sholl-Franco 《Psychology Research》 2024年第2期45-56,共12页
The present study aims to establish a literature review on intervention programs for executive functions(EFs)through the use of fundamental motor skills,from a neuropsychopedagogical perspective in subjects with Devel... The present study aims to establish a literature review on intervention programs for executive functions(EFs)through the use of fundamental motor skills,from a neuropsychopedagogical perspective in subjects with Developmental Coordination Disorder(DCD).An exploratory study was carried out through an integrative literature review.The research was carried out in the Scientific databases Electronic Library Online(SciELO),Latin American and Caribbean Literature in Health Sciences(LILACS),Virtual Health Library-Psychology Brazil(BVSPSI),Electronic Journals of Psychology(PePSIC),in the periodicals available in the Brazilian Digital Library of Theses and Dissertations(BDTD)and on the website of the Coordination for the Improvement of Higher Education Personnel(CAPES).The covering publications took place from 2018 to 2023,14 articles were selected for analysis.This literature review made it possible to create strategies for stimulating EF and Visuomotor Functions so that educators and other professionals can better deal with students with DCD.It was perceived the need to carry out and develop more empirical research regarding the intervention of EFs and Visuomotor Functions by educators and professionals,with a greater sampling amplitude,to increase the number of studies that enable interventions both in children and in teenagers with DCD. 展开更多
关键词 developmental coordination disorder executive functions school neuropsychology stimulation of executive functions
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The Mediating Effect of Digital Transformation on the Link Between Executive Overconfidence and Corporate Green Innovation
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作者 Zhu Yong Zhu Beibei 《Contemporary Social Sciences》 2024年第5期51-69,共19页
Green technological innovation is crucial for the manufacturing industry’s green transformation and sustainable development.This study examines the impact of executive overconfidence on corporate green innovation,foc... Green technological innovation is crucial for the manufacturing industry’s green transformation and sustainable development.This study examines the impact of executive overconfidence on corporate green innovation,focusing on the internal drivers of corporate innovation and using a sample of Shanghai and Shenzhen A-share listed manufacturing companies from 2013 to 2020.We further examine the mediating role of digital transformation and the moderating role of external attention.The findings indicate that executive overconfidence promotes corporate green technological innovation.Overconfident executives enhance green innovation by accelerating digital transformation.Moreover,external attention from analysts and media positively moderates the relationship between executive overconfidence and corporate green innovation.Heterogeneity analysis reveals that the positive impact of executive overconfidence on green innovation is more significant in non-state-owned enterprises,high-tech firms,and enterprises with lower pollution levels. 展开更多
关键词 executive overconfidence digital transformation green innovation
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Perspectives and Experiences of Education Stakeholders: A Quantitative Study on the Adoption of Artificial Intelligence in Executive Training Using Structural Equation Modeling
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作者 El Mostafa Atoubi Rachid Jahidi 《Intelligent Information Management》 2024年第2期104-120,共17页
The recent increase in the use of artificial intelligence has led to fundamental changes in the development of training and teaching methods for executive education. However, the success of artificial intelligence in ... The recent increase in the use of artificial intelligence has led to fundamental changes in the development of training and teaching methods for executive education. However, the success of artificial intelligence in regional centers for teaching and training professions will depend on the acceptance of this technology by young executive trainees. This article discusses the potential benefits of adopting AI in executive training institutions in Morocco, specifically focusing on CRMEF Casablanca Settat. Based on the Unified Theory of Acceptance and Use of Technology (UTAUT) (Venkatesh et al., 2003), this study proposes a model to identify the factors influencing the acceptance of artificial intelligence in regional centers for teaching professions and training in Morocco. To achieve this, a structural equation modeling approach was used to quantitatively describe the impact of each factor on AI adoption, utilizing data collected from 173 young executive trainees. The results indicate that perceived ease of use, perceived usefulness, trainer influence, and personal innovativeness influence the intention to use artificial intelligence. Our research provides managers of CRMEFs with a set of practical recommendations to enhance the implementation conditions of an artificial intelligence system. It aims to understand which factors should be considered in designing an artificial intelligence system within regional centers for teaching professions and training (CRMEFs). 展开更多
关键词 Artificial Intelligence Technology Acceptance Intention to Use UTAUT Model Personal Innovativeness of Young executive Trainees
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Cerebral arterial blood flow,attention,and executive and cognitive functions in depressed patients after acute hypertensive cerebral hemorrhage
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作者 Ya-Zhao Zhang Cong-Yi Zhang +2 位作者 Ya-Nan Tian Yi Xiang Jian-Hui Wei 《World Journal of Clinical Cases》 SCIE 2024年第19期3815-3823,共9页
BACKGROUND Intracerebral hemorrhage mainly occurs in middle-aged and elderly patients with hypertension,and surgery is currently the main treatment for hypertensive cerebral hemorrhage,but the bleeding caused by surge... BACKGROUND Intracerebral hemorrhage mainly occurs in middle-aged and elderly patients with hypertension,and surgery is currently the main treatment for hypertensive cerebral hemorrhage,but the bleeding caused by surgery will cause damage to the patient's nerve cells,resulting in cognitive and motor dysfunction,resulting in a decline in the patient's quality of life.AIM To investigate associations between cerebral arterial blood flow and executive and cognitive functions in depressed patients after acute hypertensive cerebral hemorrhage.METHODS Eighty-nine patients with depression after acute hypertensive cerebral hemorrhage who were admitted to our hospital between January 2019 and July 2021 were selected as the observation group,while 100 patients without depression who had acute hypertensive cerebral hemorrhage were selected as the control group.The attention span of the patients was assessed using the Paddle Pin Test while executive function was assessed using the Wisconsin Card Sorting Test(WCST)and cognitive function was assessed using the Montreal Cognitive Assessment Scale(MoCA).The Hamilton Depression Rating Scale(HAMD-24)was used to evaluate the severity of depression of involved patients.Cerebral arterial blood flow was measured in both groups.RESULTS The MoCA score,net scores I,II,III,IV,and the total net score of the scratch test in the observation group were significantly lower than those in the control group(P<0.05).Concurrently,the total number of responses,number of incorrect responses,number of persistent errors,and number of completed responses of the first classification in the WCST test were significantly higher in the observation group than those in the control group(P<0.05).Blood flow in the basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery was significantly lower in the observation group than in the control group(P<0.05).The basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery were positively correlated with the net and total net scores of each part of the Paddle Pin test and the MoCA score(P<0.05),and negatively correlated with each part of the WCST test(P<0.05).In the observation group,the post-treatment improvement was more prominent in the Paddle Pin test,WCST test,HAMD-24 score,and MoCA score compared with those in the pre-treatment period(P<0.05).Blood flow in the basilar artery,left middle cerebral artery,right middle cerebral artery,left anterior cerebral artery,and right anterior cerebral artery significantly improved in the observation group after treatment(P<0.05).CONCLUSION Impaired attention,and executive and cognitive functions are correlated with cerebral artery blood flow in patients with depression after acute hypertensive cerebral hemorrhage and warrant further study. 展开更多
关键词 Acute hypertensive cerebral hemorrhage DEPRESSION Cerebral arterial blood flow ATTENTION executive ability Cognitive function
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Clinical study of different modes of repetitive transcranial magnetic stimulation in the treatment of post‑stroke executive dysfunction
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作者 TIAN Geng‑run WANG Shi‑yan +5 位作者 BI Ying‑li GONG Zun‑ke WANG Xiang WANG Mi LU Si‑han ZHOU Hui 《Journal of Hainan Medical University》 CAS 2023年第12期35-40,共6页
Objective:To investigate the clinical efficacy of intermittent theta burst stimulation(iTBS)and high frequency repetitive transcranial magnetic stimulation(rTMS)on post‑stroke executive impairment(PSEI).Methods:Ninety... Objective:To investigate the clinical efficacy of intermittent theta burst stimulation(iTBS)and high frequency repetitive transcranial magnetic stimulation(rTMS)on post‑stroke executive impairment(PSEI).Methods:Ninety patients with PSEI who were hospitalized in the rehabilitation department of Xuzhou Central Hospital and Xuzhou Rehabilitation Hospital from April 2021 to June 2022 were selected and divided into iTBS group,high‑frequency group and control group.All three groups of patients received routine rehabilitation training,given rTMS treatment with iTBS,10 Hz and shame stimulation for 4 weeks.Before and after treatment,all the patients were evaluated with the Montreal cognitive assessment(MoCA),the frontal assessment battery(FAB),troop color‑word test(SCWT),shape trails test(STT),digit span test(DST)and event related potential P300.Results:After treatment,MoCA,FAB,SCWT,STT,DST scores,P300 latency and amplitude were significantly better in the three groups than before treatment(P<0.05).MoCA,FAB,SCWT,STT‑B,DST scores,P300 latency and amplitude in the iTBS group and high‑frequency group were better than in the control group,with significant differences(P<0.05).The difference between iTBS group and high‑frequency group was not statistically significant(P>0.05).Conclusion:iTBS can improve PSEI,and the efficacy is comparable to 10Hz rTMS.iTBS takes less time with better efficiency,and it is worth popularizing and applying in clinic. 展开更多
关键词 Transcranial magnetic stimulation Theta burst stimulation STROKE executive impairment Cognitive impairment
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Frontal Sinus Fractures: Management at the Yalgado Ouedraogo University Hospital Centre (Burkina Faso)
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作者 Arsène Coulibaly Patrik Gane-Bang +2 位作者 Joseph Wend-Toin Biogo Ibraïma Traoré Tarcissus Konsem 《Open Journal of Stomatology》 2024年第1期42-54,共13页
Introduction: Frontal sinus fractures are potentially serious. They are defined as a solution of continuity, open or closed, of one or both bone tables of the frontal sinus. This study aims to report on the management... Introduction: Frontal sinus fractures are potentially serious. They are defined as a solution of continuity, open or closed, of one or both bone tables of the frontal sinus. This study aims to report on the management of them at the Yalgado OUEDRAOGO University Hospital Centre. Methodology: It is a descriptive cross-sectional study with retrospective collection from January 01, 2016 to December 31, 2018. Patients with frontal sinus fractures were managed at the Yalgado OUEDRAOGO University Hospital Centre through CT-scan proof. Results: Over three years, a total of 102 cases of frontal sinus fractures were collected with 29.9 years as average age. There were 96 men. Workers in the informal sector and pupils/students represented 58.90% of patients. The residence of the patients was urban in 68.80% of cases and rural in 31.40%. Road traffic accidents (RTAs) happened in 90.20%, and involved 2-wheelers in 98.20%. None of these drivers was wearing a helmet. The type III frontal fracture of Ioannides et al. represented 51.9% of cases. In 89.21% of cases, other facial and/or cranioencephalic injuries were compounded to frontal sinus fractures. No surgical management was observed in 82 (80.39%) patients and surgical management in 20 (19.61%) patients. The outcome was favourable, but sequelae and/or complications were noted in 10 patients who had surgery and 30 patients who did not. Conclusion: These results enforce helmet wearing for all riders of two-wheeled machines. In addition, vaccinations to prevent meningitis in frontal sinus fractures with dural breach should be systematic. 展开更多
关键词 MANAGEMENT frontal Sinus Fracture Burkina Faso
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Topographical Analysis of Frontal Lobe Executive Functions in Patients Following a Stroke
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作者 Roberta Márcia Torres Kristiana Cerqueira Mousinho +6 位作者 Liércio Pinheiro Nathália Costa Toledo Pacheco Piatti Taise Almeida Cavalcante Aline da Silva Amorim Ana Karolina Barros de Jesus Maria Wylianna Oliveira dos Santos Euclides Maurício Trindade Filho 《World Journal of Neuroscience》 2016年第2期143-150,共8页
Objective: This study aimed to carry out a topographical analysis of frontal lobe executive function components in post-stroke patients. Methods: A descriptive, cross-sectional study. The assessment using the WCST (Wi... Objective: This study aimed to carry out a topographical analysis of frontal lobe executive function components in post-stroke patients. Methods: A descriptive, cross-sectional study. The assessment using the WCST (Wisconsin Card Sorting Test) included sixteen patients with a clinical diagnosis of CVA and frontal lobe impairment. Results from the two groups were compared (patients with right frontal lobe impairment and patients with left frontal lobe impairment). Statistical analysis was performed using the program “Statistical Package for Social Sciences” (SPSS) Version 20.0. For comparison between groups was used Mann-Whitney test and considered the alpha level of 0.05 on the statistically significant results. Results: There was no statistically significant difference between the groups, thus showing that executive functions are symmetrically distributed across the frontal lobes. Conclusion: Executive functions are symmetrically organized across the two frontal lobes, since the comparison between the groups did not demonstrate a statistically significant difference for any of the variables of WSCT. 展开更多
关键词 executive Function STROKE frontal Lobe NEUROPSYCHOLOGY
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Planning,monitoring and replanning techniques for handling abnormity in HTN-based planning and execution
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作者 KANG Kai CHENG Kai +2 位作者 SHAO Tianhao ZHANG Hongjun ZHANG Ke 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第5期1264-1275,共12页
A framework that integrates planning,monitoring and replanning techniques is proposed.It can devise the best solution based on the current state according to specific objectives and properly deal with the influence of... A framework that integrates planning,monitoring and replanning techniques is proposed.It can devise the best solution based on the current state according to specific objectives and properly deal with the influence of abnormity on the plan execution.The framework consists of three parts:the hierarchical task network(HTN)planner based on Monte Carlo tree search(MCTS),hybrid plan monitoring based on forward and backward and norm-based replanning method selection.The HTN planner based on MCTS selects the optimal method for HTN compound task through pre-exploration.Based on specific objectives,it can identify the best solution to the current problem.The hybrid plan monitoring has the capability to detect the influence of abnormity on the effect of an executed action and the premise of an unexecuted action,thus trigger the replanning.The norm-based replanning selection method can measure the difference between the expected state and the actual state,and then select the best replanning algorithm.The experimental results reveal that our method can effectively deal with the influence of abnormity on the implementation of the plan and achieve the target task in an optimal way. 展开更多
关键词 hierarchical task network Monte carlo tree search(MCTS) PLANNING executION abnormity
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Robust Malicious Executable Detection Using Host-Based Machine Learning Classifier
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作者 Khaled Soliman Mohamed Sobh Ayman M.Bahaa-Eldin 《Computers, Materials & Continua》 SCIE EI 2024年第4期1419-1439,共21页
The continuous development of cyberattacks is threatening digital transformation endeavors worldwide and leadsto wide losses for various organizations. These dangers have proven that signature-based approaches are ins... The continuous development of cyberattacks is threatening digital transformation endeavors worldwide and leadsto wide losses for various organizations. These dangers have proven that signature-based approaches are insufficientto prevent emerging and polymorphic attacks. Therefore, this paper is proposing a Robust Malicious ExecutableDetection (RMED) using Host-based Machine Learning Classifier to discover malicious Portable Executable (PE)files in hosts using Windows operating systems through collecting PE headers and applying machine learningmechanisms to detect unknown infected files. The authors have collected a novel reliable dataset containing 116,031benign files and 179,071 malware samples from diverse sources to ensure the efficiency of RMED approach.The most effective PE headers that can highly differentiate between benign and malware files were selected totrain the model on 15 PE features to speed up the classification process and achieve real-time detection formalicious executables. The evaluation results showed that RMED succeeded in shrinking the classification timeto 91 milliseconds for each file while reaching an accuracy of 98.42% with a false positive rate equal to 1.58. Inconclusion, this paper contributes to the field of cybersecurity by presenting a comprehensive framework thatleverages Artificial Intelligence (AI) methods to proactively detect and prevent cyber-attacks. 展开更多
关键词 Portable executable MALWARE intrusion detection CYBERSECURITY zero-day threats Host IntrusionDetection System(HIDS) machine learning Anomaly-based Intrusion Detection System(AIDS) deep learning
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从“executive”一词看香港行政长官的法律地位 被引量:5
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作者 张龑 叶一舟 《港澳研究》 2016年第2期22-29,93-94,共10页
executive一词作为一个重要的法政术语,具有执政权与执行权的双重意涵。在一国的法律及政治体系中,执政权直接与主权意志的实现及主权权力的行使紧密联系,是一种比行政权更为全面和核心的权力。明确执政权的地位与内涵,首先有助于重新... executive一词作为一个重要的法政术语,具有执政权与执行权的双重意涵。在一国的法律及政治体系中,执政权直接与主权意志的实现及主权权力的行使紧密联系,是一种比行政权更为全面和核心的权力。明确执政权的地位与内涵,首先有助于重新认识现代政治框架中的权力关系,其次有助于认清现实问题的症结所在并提出具有针对性的回应。现代政治框架中的权力关系是一个三维立体结构,处于权力关系中的主体之地位和功能只有在政治体的立体结构中才能得到整全理解。在我国的上述立体结构中,香港特区行政长官具有类似于执政者的某种地位和功能,而绝非仅是传统权力分立理念下的行政分支首脑。 展开更多
关键词 一国两制 基本法 特别行政区 行政长官 执政权
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Processing Environmental Stimuli in Paranoid Schizophrenia:Recognizing Facial Emotions and Performing Executive Functions 被引量:4
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作者 YU Shao Hua ZHU Jun Peng +6 位作者 XU You ZHENG Lei Lei CHAI Hao HE Wei LIU Wei Bo LI Hui Chun WANG Wei 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2012年第6期697-705,共9页
Objective To study the contribution of executive function to abnormal recognition of facia expressions of emotion in schizophrenia patients. Methods Abnormal recognition of facial expressions of emotion was assayed ac... Objective To study the contribution of executive function to abnormal recognition of facia expressions of emotion in schizophrenia patients. Methods Abnormal recognition of facial expressions of emotion was assayed according to Japanese and Caucasian facial expressions of emotion (JACFEE), Wisconsin card sorting test {WCST), positive and negative symptom scale, and Hamilton anxiety and depression scale, respectively, in 88 paranoid schizophrenia patients and 75 healthy volunteers. Results Patients scored higher on the Positive and Negative Symptom Scale and the Hamilton Anxiety and Depression Scales, displayed lower JACFEE recognition accuracies and poorer WCST performances. The JACFEE recognition accuracy of contempt and disgust was negatively correlated with the negative symptom scale score while the recognition accuracy of fear was positively with the positive symptom scale score and the recognition accuracy of surprise was negatively with the general psychopathology score in patients. Moreover, the WCST could predict the JACFEE recognition accuracy of contempt, disgust, and sadness in patients, and the perseverative errors negatively predicted the recognition accuracy of sadness in healthy volunteers. The JACFEE recognition accuracy of sadness could predict the WCST categories in paranoid schizophrenia patients. Conclusion Recognition accuracy of social-/moral emotions, such as contempt, disgust and sadness is related to the executive function in paranoid schizophrenia patients, especially when regarding sadness. 展开更多
关键词 executive function Japanese and Caucasian facial expressions of emotion Paranoidschizophrenia Wisconsin card sorting test
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Acute exercise is associated with specific executive functions in college students with ADHD:A preliminary study 被引量:7
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作者 Jennifer I.Gapin Jeffrey D.Labban +2 位作者 Sara C.Bohall Joshua S.Wooten Yu-Kai Chang 《Journal of Sport and Health Science》 SCIE 2015年第1期89-96,共8页
Purpose: The relationship between acute exercise and executive functions in college students with attention deficit hyperactivity disorder (ADHD) has not been clearly established. The purpose of this preliminary st... Purpose: The relationship between acute exercise and executive functions in college students with attention deficit hyperactivity disorder (ADHD) has not been clearly established. The purpose of this preliminary study was to examine the difference in cognitive performance between college students with and without ADHD and to explore the effects of acute exercise on multiple aspects of executive functions and on serum brain derived neurotrophic factor (BDNF). Methods: College students (normal: n = 10; ADHD: n = 10) performed the Stroop Test, Trail Making Test, and Digit Span Test prior to and after an acute exercise intervention. Blood samples were obtained prior to the pre-test cognitive test performance and then again after exercise and prior to the post-test cognitive test performance. Results: Students with ADHD exhibited impaired executive functions, particularly on inhibition. Additionally, while acute exercise improved all aspects of executive functions in those without ADHD, acute exercise only improved inhibitory performance for those with ADHD. Further, BDNF was not influenced by acute exercise regardless of the subjects' ADHD status. Conclusion: These results provide preliminary evidence for exercise as a potential adjunct treatment for benefitting inhibition in college students with ADHD. 展开更多
关键词 COGNITION executive function NEUROTROPHINS Physical activity
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Executive function impairments in high IQ children and adolescents with ADHD 被引量:3
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作者 Thomas Edwards Brown Philipp Christian Reichel Donald Michael Quinlan 《Open Journal of Psychiatry》 2011年第2期56-65,共10页
Objective: To demonstrate that high IQ children and adolescents diagnosed with ADHD tend to suffer from executive function (EF) impairments that: a) can be identified with a combination of standardized measures and no... Objective: To demonstrate that high IQ children and adolescents diagnosed with ADHD tend to suffer from executive function (EF) impairments that: a) can be identified with a combination of standardized measures and normed self-report data;and b) occur more frequently in this group than in the general population. Method: From charts of 117 children and adolescents aged 6 to 17 years with high IQ ( ≥ 120) who fully met DSM-IV diagnostic criteria for ADHD, data on 8 normed measures of executive function (EF) were extracted: IQ index scores for working memory and processing speed, a standardized measure of auditory verbal memory, and 5 clusters of the Brown ADD Scale, a normed, age-graded rating scale for ADHD-related executive function impairments in daily life. Significant impairment was computed for each individual relative to age-appropriate norms for each measure and comparisons were made to base-line rates in the general population. Results: Sixty-two percent of participants were significantly impaired on at least 5 of these 8 markers of EF. Chi-square comparisons of scores from these high IQ participants were significantly different (p < 0.001) from standardization norms for each of the eight EF measures. Conclusions: High IQ children and adolescents with ADHD, despite their cognitive strengths, tend to suffer from significant impairments of executive functions that can be assessed with these measures;incidence of these impairments is significantly greater than in the general population. These results are fully consistent with data on high IQ adults diagnosed with ADHD. 展开更多
关键词 ADHD executive FUNCTIONS HIGH IQ Working Memory Processing Speed
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Executive functioning in TBI from rehabilitation to social reintegration: COMPASS^(goal), a randomized controlled trial(grant: 1I01RX000637-01A3 by the VA ORD RR&D, 2013–2016) 被引量:1
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作者 Alexander V.Libin Joel Scholten +11 位作者 Manon Maitland Schladen Ellen Danford Nawar Shara Walter Penk Jordan Grafman Linda Resnik Dwan Bruner Samantha Cichon Miriam Philmon Brenda Tsai Marc Blackman Alexander Dromerick 《Military Medical Research》 SCIE CAS 2015年第4期181-200,共20页
Background: Traumatic brain injury is a major health problem that frequently leads to deficits in executive function. Self-regulation processes, such as goal-setting, may become disordered after traumatic brain injury... Background: Traumatic brain injury is a major health problem that frequently leads to deficits in executive function. Self-regulation processes, such as goal-setting, may become disordered after traumatic brain injury, particularly when the frontal regions of the brain and their connections are involved. Such impairments reduce injured veterans' ability to return to work or school and to regain satisfactory personal lives. Understanding the neurologically disabling effects of brain injury on executive function is necessary for both the accurate diagnosis of impairment and the individual tailoring of rehabilitation processes to help returning service members recover independent function.Methods/design: The COMPASSgoal(Community Participation through Self-Efficacy Skills Development) program develops and tests a novel patient-centered intervention framework for community reintegration psychosocial research in veterans with mild traumatic brain injury. COMPASSgoal integrates the principles and best practices of goal self-management. Goal setting is a core skill in self-management training by which persons with chronic health conditions learn to improve their status and decrease symptom effects. Over a three-year period, COMPASSgoal will recruit 110 participants with residual executive dysfunction three months or more post-injury. Inclusion criteria combine both clinical diagnosis and standardized scores that are >1 SD from the normative score on the Frontal Systems Rating Scale. Participants are randomized into two groups: goal-management(intervention) and supported discharge(control). The intervention is administered in eight consecutive, weekly sessions. Assessments occur at enrollment, post-intervention/supported discharge, and three months post-treatment follow-up.Discussion: Goal management is part of the "natural language" of rehabilitation. However, collaborative goal-setting between clinicians/case managers and clients can be hindered by the cognitive deficits that follow brain injury. Re-training returning veterans with brain injury in goal management, with appropriate help and support, would essentially treat deficits in executive function. A structured approach to goal self-management may foster greater independence and self-efficacy, help veterans gain insight into goals that are realistic for them at a given time, and help clinicians and veterans to work more effectively as true collaborators. 展开更多
关键词 executive function Traumatic brain injury GOAL-SETTING Community reintegration VETERANS Randomized controlled trial Manualized psychosocial intervention
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Language, executive functioning and symptomatology—Is fluency a transversal tool in schizophrenia? 被引量:1
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作者 Romina Rinaldi Laurent Lefebvre Julie Trappeniers 《Open Journal of Psychiatry》 2013年第4期358-369,共12页
Despite a large number of studies on fluency disorders in schizophrenia, it is still not clear whether executive functioning and fluency tasks are empirically linked and how symptomatology could specifically get invol... Despite a large number of studies on fluency disorders in schizophrenia, it is still not clear whether executive functioning and fluency tasks are empirically linked and how symptomatology could specifically get involved on these influences. We carried out analyses of performances in several verbal fluency tasks, a non-verbal fluency task and an executive test (FAB) in 25 schizophrenics and 25 healthy subjects matched in terms demographic data. Patients also completed the Positive and Negative Symptoms Scale in order to control for their clinical profile. Our results suggest that schizophrenic patients show both category and letter fluency deficits with a greater impairment for letter fluency. They also display poorer performances for the non-verbal fluency task. In patients, all the verbal and non-verbal fluencies are significantly correlated with the FAB total score. By contrast, in controls, only letter fluency correlates with the FAB total score, which is congruent with previous literature on the healthy mechanisms of verbal fluency. Besides, factorial analyses show that symptomatology is specifically related to particular indexes of fluency tasks. Taken together, these data lead to support the hypothesis of retrieval rather than semantic difficulties and alargest involvement of executive functioning in schizophrenics during tasks that require a certain degree of efficiency, with performance being influenced by the clinical profile. Yet, the relation between fluency scores and executive functioning has to be more intensively explored and further studies should include semantic memory measures that fit with pathology’s constraints and characteristics. 展开更多
关键词 SCHIZOPHRENIA executive Functions SYMPTOMATOLOGY FLUENCY
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Executive Compensation and Corporate Financial Performance: Empirical Evidences on Brazilian Industrial Companies 被引量:4
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作者 Elizabeth Krauter Almir Ferreira de Sousa 《Journal of Modern Accounting and Auditing》 2013年第5期650-661,共12页
This survey investigated the relationship between executive compensation and the financial performance of companies. It is hypothesized that a company can utilize its pay system to direct executives' efforts toward i... This survey investigated the relationship between executive compensation and the financial performance of companies. It is hypothesized that a company can utilize its pay system to direct executives' efforts toward its strategic business objectives, thus contributing to higher levels of corporate financial performance. The survey data consisted of a secondary and non-probabilistic sample of 44 Brazilian industrial companies. In order to operationalize the independent remuneration variable, the authors used average monthly salary, average variable salary, and three indices that were created for this survey: benefits, career, and development. These indices measure the access to benefits, mechanisms for stimulating and supporting careers, and mechanisms to encourage education and professional development that companies offer to their directors, vice presidents, and chief executive officers (CEOs), who are referred to in this paper by the term "executive". The remuneration data are from fiscal year 2006. In order to operationalize the financial performance variable, two accounting indicators were used: sales growth and return on equity (ROE) for fiscal years 2006 and 2007. The size of the companies was used as a control variable. The results of a multiple regression analysis do not support the hypothesis that there is a positive and significant relationship between executive compensation and corporate financial performance. 展开更多
关键词 COMPENSATION executive compensation financial performance industrial companies Brazil
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Effectiveness of Mindfulness Training in Enhancing Executive Function and Decreasing Symptoms of Depression and Anxiety in Patients with Multiple Sclerosis (MS) 被引量:1
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作者 Mahsa Amiri Mehdi Rabiei Vahid Donyavi 《Journal of Behavioral and Brain Science》 2016年第8期329-336,共8页
The purpose of the present study was to evaluate the effectiveness of mindfulness training in enhancing executive function and decreasing symptoms of depression and anxiety in multiple sclerosis patients. The populati... The purpose of the present study was to evaluate the effectiveness of mindfulness training in enhancing executive function and decreasing symptoms of depression and anxiety in multiple sclerosis patients. The population in this study consisted of people with MS who referred to Karaj city MS society in 1394. These people didn’t experience medicinal changes during the study period and their expanded disability status score (EDSS) was between 0 and 5.5. 40 of them were randomly selected and placed into two experimental and control groups (20 for the experimental and the other for the control group). The treatment of mindfulness training was held in 8 sessions of group training, once a week and for 2 hours. The statistical method of multivariate analysis of covariance was used. The measurement tools were the State-Trait Anxiety Inventory (STAI), the Beck Depression Inventory-II (BDI-II) and the Wisconsin Card Sorting Test (WCST). After all, the results in both groups were compared and evaluated by the use of analysis of covariance. The results showed significant differences in symptoms of anxiety and depression between the two groups (p 0.05). Generally, the results of this research showed positive effects of mindfulness training on reducing anxiety and depression among patients with MS and ineffectiveness of mindfulness training on their executive function. Therefore, considering that there is no certain treatment for MS plus results of this study, the application of mindfulness training can be quite useful to reduce levels of anxiety and depression in patients with MS. 展开更多
关键词 MINDFULNESS executive Function DEPRESSION ANXIETY Multiple Sclerosis Patients
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Association between central obesity and executive function as assessed by stroop task performance:A functional near-infrared spectroscopy study 被引量:1
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作者 Zhangyan Deng Qin Huang +3 位作者 Jiaai Huang Weixia Zhang Changzhu Qi Xia Xu 《Journal of Innovative Optical Health Sciences》 SCIE EI CAS 2018年第1期37-46,共10页
Recent studies have suggested a link between executive function(EF)and obesity.Studies oftenadopt body mass index(BM),which reflects the distribution of subcutaneous fat,as the solemarker of obesity;however,BMI is ina... Recent studies have suggested a link between executive function(EF)and obesity.Studies oftenadopt body mass index(BM),which reflects the distribution of subcutaneous fat,as the solemarker of obesity;however,BMI is inappropriate to distinguish central obesity,which indicatesthe centralized distribution of visceral fat.Visceral fat compared with subcutaneous fat repre-sents greater relative lipid turnover and may increase the risk of cognitive decline in older adults.However,the relationship between EF and central obesity is largely unknown,particularly inyoung adults.Therefore,we used waist circumference(WC)as a marker of central obesity andinvestigated diferent sensitivities between BMI and WC in the brain function.A total of 26healthy young adults(aged 18-25 years;42%female)underwent functional near-infrared spec-troscopy assessments.EF was assessed using the Stroop task,which is a classical measurementof EF.A significant Stroop effect was observed in the behavioral and hemodynamic data.Inaddition,we observed that behavioral interference on the Stroop task varied much more insubjects with higher BMI and WC than those subjects with lower.Elevated BMI and WC wereassociated with a decreased hemodynamic response during the Stroop task specifically in the pre-frontal cortex(PFC).Compared to BMI,WC was more closely connected with inhibitory controland revealed right lateralized PFC activation.Our findings suggest that WC is a reliable indicatorof brain function in young adults and propose a relationship bet ween EF and central obesity. 展开更多
关键词 executive function central obesity FNIRS young adult
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Impact of Auditory-Verbal Therapy on executive functions in children with Cochlear Implants 被引量:1
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作者 Mohammad Ashori 《Journal of Otology》 CSCD 2022年第3期130-135,共6页
Objective: Auditory-Verbal Therapy(AVT) can be considered one of the best practices for children with Cochlear Implants(CIs) who show impairments in cognitive skills such as executive functions. Hence,this research ex... Objective: Auditory-Verbal Therapy(AVT) can be considered one of the best practices for children with Cochlear Implants(CIs) who show impairments in cognitive skills such as executive functions. Hence,this research examined the impact of AVT on the executive functions in children with CIs.Methods: This was a randomized case control study with pre-and post-intervention assessments. The participants were 36 children with CIs and their mothers. They were randomly selected from rehabilitation centers and deaf pre-schools, and randomly allocated to a control(n = 18) and a study(n = 18)group. The mean age of the children in the study and control groups was 3.11 ± 0.31 years and 3.20 ± 0.29years, respectively. Participants in the study group received 20 sessions of AVT over 10 weeks at twice a week, while those in the control group did not. All mothers completed the Behavior Rating Inventory of Executive Function Pre-school Version(BRIEF-P) before and after children in the study group completed their AVT intervention. Data were analyzed by MANCOVA.Results: The results suggest that AVT significantly influenced executive functions and all subscales including shifting, inhibition, emotional control, working memory and organization/planning in children with CIs.Conclusions: These findings suggest that AVT may be effective in resulting in positive outcomes and may play an important role in improving executive functions in children with CIs. 展开更多
关键词 Auditory-verbal therapy Early intervention executive functions
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