In this paper,we propose the Two-way Deep Reinforcement Learning(DRL)-Based resource allocation algorithm,which solves the problem of resource allocation in the cognitive downlink network based on the underlay mode.Se...In this paper,we propose the Two-way Deep Reinforcement Learning(DRL)-Based resource allocation algorithm,which solves the problem of resource allocation in the cognitive downlink network based on the underlay mode.Secondary users(SUs)in the cognitive network are multiplexed by a new Power Domain Sparse Code Multiple Access(PD-SCMA)scheme,and the physical resources of the cognitive base station are virtualized into two types of slices:enhanced mobile broadband(eMBB)slice and ultrareliable low latency communication(URLLC)slice.We design the Double Deep Q Network(DDQN)network output the optimal codebook assignment scheme and simultaneously use the Deep Deterministic Policy Gradient(DDPG)network output the optimal power allocation scheme.The objective is to jointly optimize the spectral efficiency of the system and the Quality of Service(QoS)of SUs.Simulation results show that the proposed algorithm outperforms the CNDDQN algorithm and modified JEERA algorithm in terms of spectral efficiency and QoS satisfaction.Additionally,compared with the Power Domain Non-orthogonal Multiple Access(PD-NOMA)slices and the Sparse Code Multiple Access(SCMA)slices,the PD-SCMA slices can dramatically enhance spectral efficiency and increase the number of accessible users.展开更多
Although modulation classification based on deep neural network can achieve high Modulation Classification(MC)accuracies,catastrophic forgetting will occur when the neural network model continues to learn new tasks.In...Although modulation classification based on deep neural network can achieve high Modulation Classification(MC)accuracies,catastrophic forgetting will occur when the neural network model continues to learn new tasks.In this paper,we simulate the dynamic wireless communication environment and focus on breaking the learning paradigm of isolated automatic MC.We innovate a research algorithm for continuous automatic MC.Firstly,a memory for storing representative old task modulation signals is built,which is employed to limit the gradient update direction of new tasks in the continuous learning stage to ensure that the loss of old tasks is also in a downward trend.Secondly,in order to better simulate the dynamic wireless communication environment,we employ the mini-batch gradient algorithm which is more suitable for continuous learning.Finally,the signal in the memory can be replayed to further strengthen the characteristics of the old task signal in the model.Simulation results verify the effectiveness of the method.展开更多
Spectrum sensing is a key technology for cognitive radios.We present spectrum sensing as a classification problem and propose a sensing method based on deep learning classification.We normalize the received signal pow...Spectrum sensing is a key technology for cognitive radios.We present spectrum sensing as a classification problem and propose a sensing method based on deep learning classification.We normalize the received signal power to overcome the effects of noise power uncertainty.We train the model with as many types of signals as possible as well as noise data to enable the trained network model to adapt to untrained new signals.We also use transfer learning strategies to improve the performance for real-world signals.Extensive experiments are conducted to evaluate the performance of this method.The simulation results show that the proposed method performs better than two traditional spectrum sensing methods,i.e.,maximum-minimum eigenvalue ratio-based method and frequency domain entropy-based method.In addition,the experimental results of the new untrained signal types show that our method can adapt to the detection of these new signals.Furthermore,the real-world signal detection experiment results show that the detection performance can be further improved by transfer learning.Finally,experiments under colored noise show that our proposed method has superior detection performance under colored noise,while the traditional methods have a significant performance degradation,which further validate the superiority of our method.展开更多
Hyperthermia-induced decline in cognitive performance is a moderate complication that poses challenges to the maintenance of safety. Although the underlying mechanism can be attributed to the disruption of brain netwo...Hyperthermia-induced decline in cognitive performance is a moderate complication that poses challenges to the maintenance of safety. Although the underlying mechanism can be attributed to the disruption of brain networks, the propensity remains unclear. This study aimed to test the hypothesis that the extent of the alterations in cognitive performance is governed by the activity of deep brain structures, including monoaminergic neural systems. A decline in cognitive performance during mild hyperthermia and the beneficial effects of neck cooling were demonstrated using the Continuous Performance Test as a battery of cognitive tasks. Aspects of cognitive performance were characterized using the deep-brain activity (DBA) index as a neural activity parameter and the State-Trait Anxiety Inventory to assess the extent of alterations in cognitive performance as an individual measure. It was found that a higher average DBA index during tasks is essential for high cognitive performance in the heat. This beneficial effect of DBA is governed by the upper brainstem. This DBA benefit is more significant for individuals with higher average DBA indices at rest in a normal environment. Individual differences in cognitive performance in the heat are governed by differences in DBA. In addition, the beneficial effect of DBA on cognitive performance in heat only applies under conditions including neck cooling. This limited neck-cooling effect is attributed to anti-homeostatic thermoregulatory responses to cognitive tasks regulated by DBA.展开更多
To solve the contradiction between limited spectrum resources and increasing communication demand,this paper proposes a wireless resource allocation scheme based on the Deep Q Network(DQN)to allocate radio resources i...To solve the contradiction between limited spectrum resources and increasing communication demand,this paper proposes a wireless resource allocation scheme based on the Deep Q Network(DQN)to allocate radio resources in a downlink multi-user cognitive radio(CR)network with slicing.Secondary users(SUs)are multiplexed using non-orthogonal multiple access(NOMA).The SUs use the hybrid spectrum access mode to improve the spectral efficiency(SE).Considering the demand for multiple services,the enhanced mobile broadband(eMBB)slice and ultrareliable low-latency communication(URLLC)slice were established.The proposed scheme can maximize the SE while ensuring Quality of Service(QoS)for the users.This study established a mapping relationship between resource allocation and the DQN algorithm in the CR-NOMA network.According to the signal-to-interference-plusnoise ratio(SINR)of the primary users(PUs),the proposed scheme can output the optimal channel selection and power allocation.The simulation results reveal that the proposed scheme can converge faster and obtain higher rewards compared with the Q-Learning scheme.Additionally,the proposed scheme has better SE than both the overlay and underlay only modes.展开更多
There is a growing interest in the diagnosis and treatment of patients with dementia and cognitive impairment at an early stage. Recent imaging studies have explored neural mechanisms underlying cognitive dysfunction ...There is a growing interest in the diagnosis and treatment of patients with dementia and cognitive impairment at an early stage. Recent imaging studies have explored neural mechanisms underlying cognitive dysfunction based on brain network architecture and functioning. The dorsal anterior cingulate cortex (dACC) is thought to regulate large-scale intrinsic brain networks, and plays a primary role in cognitive processing with the anterior insular cortex (aIC), thus providing salience functions. Although neural mechanisms have been elucidated at the connectivity level by imaging studies, their understanding at the activity level still remains unclear because of limited time-based resolution of conventional imaging techniques. In this study, we investigated temporal activity of the dACC during word (verb) generation tasks based on our newly developed event-related deep brain activity (ER-DBA) method using occipital electroencephalogram (EEG) alpha-2 powers with a time resolution of a few hundred milliseconds. The dACC exhibited dip-like temporal waveforms indicating deactivation in an initial stage of each trial when appropriate verbs were successfully generated. By contrast, monotonous increase was observed for incorrect responses and a decrease was detected for no responses. The dip depth was correlated with the percentage of success. Additionally, the dip depth linearly increased with increasing slow component of the DBA index at rest across all subjects. These findings suggest that dACC deactivation is essential for cognitive processing, whereas its activation is required for goal-oriented behavioral outputs, such as cued speech. Such dACC functioning, represented by the dip depth, is supported by the activity of the upper brainstem region including monoaminergic neural systems.展开更多
The exponential growth of Internet of Things(IoT)and 5G networks has resulted in maximum users,and the role of cognitive radio has become pivotal in handling the crowded users.In this scenario,cognitive radio techniqu...The exponential growth of Internet of Things(IoT)and 5G networks has resulted in maximum users,and the role of cognitive radio has become pivotal in handling the crowded users.In this scenario,cognitive radio techniques such as spectrum sensing,spectrum sharing and dynamic spectrum access will become essential components in Wireless IoT communication.IoT devices must learn adaptively to the environment and extract the spectrum knowledge and inferred spectrum knowledge by appropriately changing communication parameters such as modulation index,frequency bands,coding rate etc.,to accommodate the above characteristics.Implementing the above learning methods on the embedded chip leads to high latency,high power consumption and more chip area utilisation.To overcome the problems mentioned above,we present DEEP HOLE Radio sys-tems,the intelligent system enabling the spectrum knowledge extraction from the unprocessed samples by the optimized deep learning models directly from the Radio Frequency(RF)environment.DEEP HOLE Radio provides(i)an opti-mized deep learning framework with a good trade-off between latency,power and utilization.(ii)Complete Hardware-Software architecture where the SoC’s coupled with radio transceivers for maximum performance.The experimentation has been carried out using GNURADIO software interfaced with Zynq-7000 devices mounting on ESP8266 radio transceivers with inbuilt Omni direc-tional antennas.The whole spectrum of knowledge has been extracted using GNU radio.These extracted features are used to train the proposed optimized deep learning models,which run parallel on Zynq-SoC 7000,consuming less area,power,latency and less utilization area.The proposed framework has been evaluated and compared with the existing frameworks such as RFLearn,Long Term Short Memory(LSTM),Convolutional Neural Networks(CNN)and Deep Neural Networks(DNN).The outcome shows that the proposed framework has outperformed the existing framework regarding the area,power and time.More-over,the experimental results show that the proposed framework decreases the delay,power and area by 15%,20%25%concerning the existing RFlearn and other hardware constraint frameworks.展开更多
Alzheimer’s Disease(AD)is a progressive neurological disease.Early diagnosis of this illness using conventional methods is very challenging.Deep Learning(DL)is one of the finest solutions for improving diagnostic pro...Alzheimer’s Disease(AD)is a progressive neurological disease.Early diagnosis of this illness using conventional methods is very challenging.Deep Learning(DL)is one of the finest solutions for improving diagnostic procedures’performance and forecast accuracy.The disease’s widespread distribution and elevated mortality rate demonstrate its significance in the older-onset and younger-onset age groups.In light of research investigations,it is vital to consider age as one of the key criteria when choosing the subjects.The younger subjects are more susceptible to the perishable side than the older onset.The proposed investigation concentrated on the younger onset.The research used deep learning models and neuroimages to diagnose and categorize the disease at its early stages automatically.The proposed work is executed in three steps.The 3D input images must first undergo image pre-processing using Weiner filtering and Contrast Limited Adaptive Histogram Equalization(CLAHE)methods.The Transfer Learning(TL)models extract features,which are subsequently compressed using cascaded Auto Encoders(AE).The final phase entails using a Deep Neural Network(DNN)to classify the phases of AD.The model was trained and tested to classify the five stages of AD.The ensemble ResNet-18 and sparse autoencoder with DNN model achieved an accuracy of 98.54%.The method is compared to state-of-the-art approaches to validate its efficacy and performance.展开更多
目的探讨近期皮质下小梗死(RSSI)患者颅内深髓静脉(DMV)可见性与不同区域血管周围间隙扩大(EPVS)及认知功能的相关性。方法回顾性连续纳入南京医科大学附属常州市第二人民医院神经内科自2022年10月至2023年10月收治的RSSI患者,所有患者...目的探讨近期皮质下小梗死(RSSI)患者颅内深髓静脉(DMV)可见性与不同区域血管周围间隙扩大(EPVS)及认知功能的相关性。方法回顾性连续纳入南京医科大学附属常州市第二人民医院神经内科自2022年10月至2023年10月收治的RSSI患者,所有患者入院后3 d内完成MR的常规及磁敏感加权成像(SWI)序列扫描。所有RSSI患者发病7 d内进行蒙特利尔认知评估(MoCA)量表评分。对所有患者基底节区(BG)和半卵圆中心区的EPVS进行分级评估和体积测量,使用DMV视觉评分对患者SWI幅度图或最小强度投影图上的DMV可见性进行评估,并将患者分为可见性较高的DMV低-中分组(评分0~12分,104例)及可见性较低的DMV高分组(评分13~18分,47例),采用单因素分析比较两组患者的临床和影像学资料,采用多因素Logistic回归和Spearman相关分析方法分析DMV可见性与BG-EPVS分级及体积的关系以及其与患者认知功能的关系。结果共纳入RSSI患者151例,平均年龄(69±10)岁,其中男92例(60.9%),女59例(39.1%)。DMV高分组RSSI患者的年龄[(76±5)岁比(65±10)岁,t=-10.875]、高血压病患者比例[78.7%(37/47)比54.8%(57/104),χ^(2)=7.879]、BG-EPVS分级、BG-EPVS体积[5.67(5.30,5.81)ln mm 3比4.61(3.66,5.30)ln mm 3,Z=-6.772]、脑白质高信号体积[7.67(6.23,8.43)ln mm 3比4.31(3.53,5.89)ln mm 3,Z=-6.501]均明显高于DMV低-中分组,差异均有统计学意义(均P<0.05)。DMV高分组RSSI患者的总胆固醇[3.74(3.20,4.39)mmol/L比4.09(3.47,4.96)mmol/L,Z=-2.082]、三酰甘油[1.20(0.78,1.86)mmol/L比1.53(1.05,1.99)mmol/L,Z=-2.343]、MoCA量表评分[21.0(20.0,22.0)分比24.0(22.0,25.0)分,Z=-9.862]均低于DMV低-中分组(均P<0.05)。其余基线资料差异均无统计学意义(均P>0.05)。多因素Logistic回归分析结果显示,较高的年龄(OR=1.181,95%CI:1.070~1.304,P=0.001)、中重度BG-EPVS(OR=2.441,95%CI:1.186~5.024,P=0.015)、较高的BG-EPVS体积(OR=4.987,95%CI:1.218~19.350,P=0.020)和较高的WMH体积(OR=1.285,95%CI:1.044~1.582,P=0.018)与较高的DMV评分相关。Spearman相关性分析结果显示,DMV评分与RSSI患者的BG-EPVS分级呈正相关(r=0.613,P<0.01),与BG-EPVS体积呈正相关(r=0.549,P<0.01),与RSSI患者的MoCA量表评分呈负相关(r=-0.449,P<0.01)。结论年龄、BG-EPVS分级、BG-EPVS体积和WMH体积与RSSI患者的DMV可见性相关;RSSI患者DMV的可见性越差,认知功能损伤越严重。展开更多
基金supported by the National Natural Science Foundation of China(Grant No.61971057).
文摘In this paper,we propose the Two-way Deep Reinforcement Learning(DRL)-Based resource allocation algorithm,which solves the problem of resource allocation in the cognitive downlink network based on the underlay mode.Secondary users(SUs)in the cognitive network are multiplexed by a new Power Domain Sparse Code Multiple Access(PD-SCMA)scheme,and the physical resources of the cognitive base station are virtualized into two types of slices:enhanced mobile broadband(eMBB)slice and ultrareliable low latency communication(URLLC)slice.We design the Double Deep Q Network(DDQN)network output the optimal codebook assignment scheme and simultaneously use the Deep Deterministic Policy Gradient(DDPG)network output the optimal power allocation scheme.The objective is to jointly optimize the spectral efficiency of the system and the Quality of Service(QoS)of SUs.Simulation results show that the proposed algorithm outperforms the CNDDQN algorithm and modified JEERA algorithm in terms of spectral efficiency and QoS satisfaction.Additionally,compared with the Power Domain Non-orthogonal Multiple Access(PD-NOMA)slices and the Sparse Code Multiple Access(SCMA)slices,the PD-SCMA slices can dramatically enhance spectral efficiency and increase the number of accessible users.
文摘Although modulation classification based on deep neural network can achieve high Modulation Classification(MC)accuracies,catastrophic forgetting will occur when the neural network model continues to learn new tasks.In this paper,we simulate the dynamic wireless communication environment and focus on breaking the learning paradigm of isolated automatic MC.We innovate a research algorithm for continuous automatic MC.Firstly,a memory for storing representative old task modulation signals is built,which is employed to limit the gradient update direction of new tasks in the continuous learning stage to ensure that the loss of old tasks is also in a downward trend.Secondly,in order to better simulate the dynamic wireless communication environment,we employ the mini-batch gradient algorithm which is more suitable for continuous learning.Finally,the signal in the memory can be replayed to further strengthen the characteristics of the old task signal in the model.Simulation results verify the effectiveness of the method.
基金supported in part by National Natural Science Foundation of China under Grant No. 61871398in part by China Postdoctoral Science Foundation under Grant No. 2018M631122
文摘Spectrum sensing is a key technology for cognitive radios.We present spectrum sensing as a classification problem and propose a sensing method based on deep learning classification.We normalize the received signal power to overcome the effects of noise power uncertainty.We train the model with as many types of signals as possible as well as noise data to enable the trained network model to adapt to untrained new signals.We also use transfer learning strategies to improve the performance for real-world signals.Extensive experiments are conducted to evaluate the performance of this method.The simulation results show that the proposed method performs better than two traditional spectrum sensing methods,i.e.,maximum-minimum eigenvalue ratio-based method and frequency domain entropy-based method.In addition,the experimental results of the new untrained signal types show that our method can adapt to the detection of these new signals.Furthermore,the real-world signal detection experiment results show that the detection performance can be further improved by transfer learning.Finally,experiments under colored noise show that our proposed method has superior detection performance under colored noise,while the traditional methods have a significant performance degradation,which further validate the superiority of our method.
文摘Hyperthermia-induced decline in cognitive performance is a moderate complication that poses challenges to the maintenance of safety. Although the underlying mechanism can be attributed to the disruption of brain networks, the propensity remains unclear. This study aimed to test the hypothesis that the extent of the alterations in cognitive performance is governed by the activity of deep brain structures, including monoaminergic neural systems. A decline in cognitive performance during mild hyperthermia and the beneficial effects of neck cooling were demonstrated using the Continuous Performance Test as a battery of cognitive tasks. Aspects of cognitive performance were characterized using the deep-brain activity (DBA) index as a neural activity parameter and the State-Trait Anxiety Inventory to assess the extent of alterations in cognitive performance as an individual measure. It was found that a higher average DBA index during tasks is essential for high cognitive performance in the heat. This beneficial effect of DBA is governed by the upper brainstem. This DBA benefit is more significant for individuals with higher average DBA indices at rest in a normal environment. Individual differences in cognitive performance in the heat are governed by differences in DBA. In addition, the beneficial effect of DBA on cognitive performance in heat only applies under conditions including neck cooling. This limited neck-cooling effect is attributed to anti-homeostatic thermoregulatory responses to cognitive tasks regulated by DBA.
基金the National Natural Science Foundation of China(Grant No.61971057).
文摘To solve the contradiction between limited spectrum resources and increasing communication demand,this paper proposes a wireless resource allocation scheme based on the Deep Q Network(DQN)to allocate radio resources in a downlink multi-user cognitive radio(CR)network with slicing.Secondary users(SUs)are multiplexed using non-orthogonal multiple access(NOMA).The SUs use the hybrid spectrum access mode to improve the spectral efficiency(SE).Considering the demand for multiple services,the enhanced mobile broadband(eMBB)slice and ultrareliable low-latency communication(URLLC)slice were established.The proposed scheme can maximize the SE while ensuring Quality of Service(QoS)for the users.This study established a mapping relationship between resource allocation and the DQN algorithm in the CR-NOMA network.According to the signal-to-interference-plusnoise ratio(SINR)of the primary users(PUs),the proposed scheme can output the optimal channel selection and power allocation.The simulation results reveal that the proposed scheme can converge faster and obtain higher rewards compared with the Q-Learning scheme.Additionally,the proposed scheme has better SE than both the overlay and underlay only modes.
文摘There is a growing interest in the diagnosis and treatment of patients with dementia and cognitive impairment at an early stage. Recent imaging studies have explored neural mechanisms underlying cognitive dysfunction based on brain network architecture and functioning. The dorsal anterior cingulate cortex (dACC) is thought to regulate large-scale intrinsic brain networks, and plays a primary role in cognitive processing with the anterior insular cortex (aIC), thus providing salience functions. Although neural mechanisms have been elucidated at the connectivity level by imaging studies, their understanding at the activity level still remains unclear because of limited time-based resolution of conventional imaging techniques. In this study, we investigated temporal activity of the dACC during word (verb) generation tasks based on our newly developed event-related deep brain activity (ER-DBA) method using occipital electroencephalogram (EEG) alpha-2 powers with a time resolution of a few hundred milliseconds. The dACC exhibited dip-like temporal waveforms indicating deactivation in an initial stage of each trial when appropriate verbs were successfully generated. By contrast, monotonous increase was observed for incorrect responses and a decrease was detected for no responses. The dip depth was correlated with the percentage of success. Additionally, the dip depth linearly increased with increasing slow component of the DBA index at rest across all subjects. These findings suggest that dACC deactivation is essential for cognitive processing, whereas its activation is required for goal-oriented behavioral outputs, such as cued speech. Such dACC functioning, represented by the dip depth, is supported by the activity of the upper brainstem region including monoaminergic neural systems.
文摘The exponential growth of Internet of Things(IoT)and 5G networks has resulted in maximum users,and the role of cognitive radio has become pivotal in handling the crowded users.In this scenario,cognitive radio techniques such as spectrum sensing,spectrum sharing and dynamic spectrum access will become essential components in Wireless IoT communication.IoT devices must learn adaptively to the environment and extract the spectrum knowledge and inferred spectrum knowledge by appropriately changing communication parameters such as modulation index,frequency bands,coding rate etc.,to accommodate the above characteristics.Implementing the above learning methods on the embedded chip leads to high latency,high power consumption and more chip area utilisation.To overcome the problems mentioned above,we present DEEP HOLE Radio sys-tems,the intelligent system enabling the spectrum knowledge extraction from the unprocessed samples by the optimized deep learning models directly from the Radio Frequency(RF)environment.DEEP HOLE Radio provides(i)an opti-mized deep learning framework with a good trade-off between latency,power and utilization.(ii)Complete Hardware-Software architecture where the SoC’s coupled with radio transceivers for maximum performance.The experimentation has been carried out using GNURADIO software interfaced with Zynq-7000 devices mounting on ESP8266 radio transceivers with inbuilt Omni direc-tional antennas.The whole spectrum of knowledge has been extracted using GNU radio.These extracted features are used to train the proposed optimized deep learning models,which run parallel on Zynq-SoC 7000,consuming less area,power,latency and less utilization area.The proposed framework has been evaluated and compared with the existing frameworks such as RFLearn,Long Term Short Memory(LSTM),Convolutional Neural Networks(CNN)and Deep Neural Networks(DNN).The outcome shows that the proposed framework has outperformed the existing framework regarding the area,power and time.More-over,the experimental results show that the proposed framework decreases the delay,power and area by 15%,20%25%concerning the existing RFlearn and other hardware constraint frameworks.
文摘Alzheimer’s Disease(AD)is a progressive neurological disease.Early diagnosis of this illness using conventional methods is very challenging.Deep Learning(DL)is one of the finest solutions for improving diagnostic procedures’performance and forecast accuracy.The disease’s widespread distribution and elevated mortality rate demonstrate its significance in the older-onset and younger-onset age groups.In light of research investigations,it is vital to consider age as one of the key criteria when choosing the subjects.The younger subjects are more susceptible to the perishable side than the older onset.The proposed investigation concentrated on the younger onset.The research used deep learning models and neuroimages to diagnose and categorize the disease at its early stages automatically.The proposed work is executed in three steps.The 3D input images must first undergo image pre-processing using Weiner filtering and Contrast Limited Adaptive Histogram Equalization(CLAHE)methods.The Transfer Learning(TL)models extract features,which are subsequently compressed using cascaded Auto Encoders(AE).The final phase entails using a Deep Neural Network(DNN)to classify the phases of AD.The model was trained and tested to classify the five stages of AD.The ensemble ResNet-18 and sparse autoencoder with DNN model achieved an accuracy of 98.54%.The method is compared to state-of-the-art approaches to validate its efficacy and performance.
文摘目的探讨近期皮质下小梗死(RSSI)患者颅内深髓静脉(DMV)可见性与不同区域血管周围间隙扩大(EPVS)及认知功能的相关性。方法回顾性连续纳入南京医科大学附属常州市第二人民医院神经内科自2022年10月至2023年10月收治的RSSI患者,所有患者入院后3 d内完成MR的常规及磁敏感加权成像(SWI)序列扫描。所有RSSI患者发病7 d内进行蒙特利尔认知评估(MoCA)量表评分。对所有患者基底节区(BG)和半卵圆中心区的EPVS进行分级评估和体积测量,使用DMV视觉评分对患者SWI幅度图或最小强度投影图上的DMV可见性进行评估,并将患者分为可见性较高的DMV低-中分组(评分0~12分,104例)及可见性较低的DMV高分组(评分13~18分,47例),采用单因素分析比较两组患者的临床和影像学资料,采用多因素Logistic回归和Spearman相关分析方法分析DMV可见性与BG-EPVS分级及体积的关系以及其与患者认知功能的关系。结果共纳入RSSI患者151例,平均年龄(69±10)岁,其中男92例(60.9%),女59例(39.1%)。DMV高分组RSSI患者的年龄[(76±5)岁比(65±10)岁,t=-10.875]、高血压病患者比例[78.7%(37/47)比54.8%(57/104),χ^(2)=7.879]、BG-EPVS分级、BG-EPVS体积[5.67(5.30,5.81)ln mm 3比4.61(3.66,5.30)ln mm 3,Z=-6.772]、脑白质高信号体积[7.67(6.23,8.43)ln mm 3比4.31(3.53,5.89)ln mm 3,Z=-6.501]均明显高于DMV低-中分组,差异均有统计学意义(均P<0.05)。DMV高分组RSSI患者的总胆固醇[3.74(3.20,4.39)mmol/L比4.09(3.47,4.96)mmol/L,Z=-2.082]、三酰甘油[1.20(0.78,1.86)mmol/L比1.53(1.05,1.99)mmol/L,Z=-2.343]、MoCA量表评分[21.0(20.0,22.0)分比24.0(22.0,25.0)分,Z=-9.862]均低于DMV低-中分组(均P<0.05)。其余基线资料差异均无统计学意义(均P>0.05)。多因素Logistic回归分析结果显示,较高的年龄(OR=1.181,95%CI:1.070~1.304,P=0.001)、中重度BG-EPVS(OR=2.441,95%CI:1.186~5.024,P=0.015)、较高的BG-EPVS体积(OR=4.987,95%CI:1.218~19.350,P=0.020)和较高的WMH体积(OR=1.285,95%CI:1.044~1.582,P=0.018)与较高的DMV评分相关。Spearman相关性分析结果显示,DMV评分与RSSI患者的BG-EPVS分级呈正相关(r=0.613,P<0.01),与BG-EPVS体积呈正相关(r=0.549,P<0.01),与RSSI患者的MoCA量表评分呈负相关(r=-0.449,P<0.01)。结论年龄、BG-EPVS分级、BG-EPVS体积和WMH体积与RSSI患者的DMV可见性相关;RSSI患者DMV的可见性越差,认知功能损伤越严重。