Abnormal characterization of dynamic functional connectivity in Alzheimer’s disease

Numerous studies have shown abnormal brain functional connectivity in individuals with Alzheimer’s disease(AD)or amnestic mild cognitive impairment(aMCI).However,most studies examined traditional resting state functional connections,ignoring the instantaneous connection mode of the whole brain.In this case-control study,we used a new method called dynamic functional connectivity(DFC)to look for abnormalities in patients with AD and aMCI.We calculated dynamic functional connectivity strength from functional magnetic resonance imaging data for each participant,and then used a support vector machine to classify AD patients and normal controls.Finally,we highlighted brain regions and brain networks that made the largest contributions to the classification.We found differences in dynamic function connectivity strength in the left precuneus,default mode network,and dorsal attention network among normal controls,aMCI patients,and AD patients.These abnormalities are potential imaging markers for the early diagnosis of AD.

Structural,Electrical,and Lithium Ion Dynamics of Li2MnO3 from Density Functional Theory

The layered Li2MnO3 is investigated by using the first-principles calculations within the GGA and GGA-t-U scheme, respectively. Within the GGA4-U approach, the calculated intercalation voltage （ranges from 4,5 V to 4.9 V） is found to be in good agreement with experiments. From the analysis of electronic structure, the pure phase Li2MnO3 is insulating, which is indicative of poor electronic-conduction properties. However, further studies of lithium ion diffusion in bulk Li2MnO3 show that unlike the two-dimensional diffusion pathways in rock salt structure layered cathode materials, lithium can diffuse in a three-dimensional pathway in Li2MnO3, with moderate lithium migration energy barrier ranges from 0.57 to 0.63 e V.

On dynamic function of cognitive context

Sperber ＆ Wilson point out the cognitive nature of context when they explicate relevance theory. Cognitive context exerts its function dynamically. The process of communication is the participation of cognitive context. Without cognitive context, the verbal communication can not be realized.

Aberrant dynamic functional connectivity of thalamocortical circuitry in major depressive disorder

Thalamocortical circuitry has a substantial impact on emotion and cognition.Previous studies have demonstrated alterations in thalamocortical functional connectivity(FC),characterized by region-dependent hypo-or hyper-connectivity,among individuals with major depressive disorder(MDD).However,the dynamical reconfiguration of the thalamocortical system over time and potential abnormalities in dynamic thalamocortical connectivity associated with MDD remain unclear.Hence,we analyzed dynamic FC(dFC)between ten thalamic subregions and seven cortical subnetworks from resting-state functional magnetic resonance images of 48 patients with MDD and 57 healthy controls(HCs)to investigate time-varying changes in thalamocortical FC in patients with MDD.Moreover,dynamic laterality analysis was conducted to examine the changes in functional lateralization of the thalamocortical system over time.Correlations between the dynamic measures of thalamocortical FC and clinical assessment were also calculated.We identified four dynamic states of thalamocortical circuitry wherein patients with MDD exhibited decreased fractional time and reduced transitions within a negative connectivity state that showed strong correlations with primary cortical networks,compared with the HCs.In addition,MDD patients also exhibited increased fluctuations in functional laterality in the thalamocortical system across the scan duration.The thalamo-subnetwork analysis unveiled abnormal dFC variability involving higher-order cortical networks in the MDD cohort.Significant correlations were found between increased dFC variability with dorsal attention and default mode networks and the severity of symptoms.Our study comprehensively investigated the pattern of alteration of the thalamocortical dFC in MDD patients.The heterogeneous alterations of dFC between the thalamus and both primary and higher-order cortical networks may help characterize the deficits of sensory and cognitive processing in MDD.

A novel algorithm for evaluating cement azimuthal density based on perturbation theory in horizontal well

Cement density monitoring plays a vital role in evaluating the quality of cementing projects,which is of great significance to the development of oil and gas.However,the presence of inhomogeneous cement distribution and casing eccentricity in horizontal wells often complicates the accurate evaluation of cement azimuthal density.In this regard,this paper proposes an algorithm to calculate the cement azimuthal density in horizontal wells using a multi-detector gamma-ray detection system.The spatial dynamic response functions are simulated to obtain the influence of cement density on gamma-ray counts by the perturbation theory,and the contribution of cement density in six sectors to the gamma-ray recorded by different detectors is obtained by integrating the spatial dynamic response functions.Combined with the relationship between gamma-ray counts and cement density,a multi-parameter calculation equation system is established,and the regularized Newton iteration method is employed to invert casing eccentricity and cement azimuthal density.This approach ensures the stability of the inversion process while simultaneously achieving an accuracy of 0.05 g/cm^(3) for the cement azimuthal density.This accuracy level is ten times higher compared to density accuracy calculated using calibration equations.Overall,this algorithm enhances the accuracy of cement azimuthal density evaluation,provides valuable technical support for the monitoring of cement azimuthal density in the oil and gas industry.

Dynamic anti-plane analysis for two symmetrically interfacial cracks near circular cavity in piezoelectric bi-materials

The present paper is exposed theoretically to the influence on the dynamic stress intensity factor （DSIF） in the piezoelectric bi-materials model with two symmet- rically permeable interracial cracks near the edges of a circular cavity, subjected to the dynamic incident anti-plane shearing wave （SH-wave）. An available theoretical method to dynamic analysis in the related research field is provided. The formulations are based on Green＇s function method. The DSIFs at the inner and outer tips of the left crack are obtained by solving the boundary value problems with the conjunction and crack- simulation technique. The numerical results are obtained by the FORTRAN language program and plotted to show the influence of the variations of the physical parameters, the structural geometry, and the wave frequencies of incident wave on the dimensionless DSIFs. Comparisons with previous work and between the inner and outer tips are con- cluded.

TIME-HARMONIC DYNAMIC GREEN'S FUNCTIONS FOR ONE-DIMENSIONAL HEXAGONAL QUASICRYSTALS

Quasicrystals have additional phason degrees of freedom not found in conventional crystals. In this paper, we present an exact solution for time-harmonic dynamic Green＇s function of one-dimensional hexagonal quasicrystals with the Laue classes 6/mh and 6/mhmm. Through the introduction of two new functions φ and ψ, the original problem is reduced to the determination of Green＇s functions for two independent Helmholtz equations. The explicit expressions of displacement and stress fields are presented and their asymptotic behaviors are discussed. The static Green＇s function can be obtained by letting the circular frequency approach zero.

STUDY ON DYNAMIC STRESS INTENSITY FACTORS OF DISK WITH A RADIAL EDGE CRACK SUBJECTED TO EXTERNAL IMPULSIVE PRESSURE

A dynamic weight function method is presented for dynamic stress intensity factors of circular disk with a radial edge crack under external impulsive pressure. The dynamic stresses in a circular disk are solved under abrupt step external pressure using the eigenfunction method. The solution consists of a quasi-static solution satisfying inhomogeneous boundary conditions and a dynamic solution satisfying homogeneous boundary conditions. By making use of Fourier- Bessel series expansion, the history and distribution of dynamic stresses in the circular disk are derived. Furthermore, the equation for stress intensity factors under uniform pressure is used as the reference case, the weight function equation for the circular disk containing an edge crack is worked out, and the dynamic stress intensity factor equation for the circular disk containing a radial edge crack can be given. The results indicate that the stress intensity factors under sudden step external pressure vary periodically with time, and the ratio of the maximum value of dynamic stress intensity factors to the corresponding static value is about 2.0.

Analysis of dynamic stress intensity factors of thick-walled cylinder under internal impulsive pressure

Dynamic stress intensity factors are evaluated for thick-walled cylinder with a radial edge crack under internal impulsive pressure. Firstly, the equation for stress intensity factors under static uniform pressure is used as the reference case, and then the weight function for a thick-walled cylinder containing a radial edge crack can be worked out. Secondly, the dynamic stresses in uncracked thick-walled cylinders are solved under internal impulsive pressure by using mode shape function method. The solution consists of a quasi-static solution satisfying inhomogeneous boundary conditions and a dynamic solution satisfying homogeneous boundary condi- tions, and the history and distribution of dynamic stresses in thick-walled cylinders are derived in terms of Fourier-Bessel series. Finally, the dynamic stress intensity factor equations for thick-walled cylinder containing a radial edge crack sub- jected to internal impulsive pressure are given by dynamic weight function method. The finite element method is utilized to verify the results of numerical examples, showing the validity and feasibility of the proposed method.

Equilibrium dynamics of the sub-Ohmic spin-boson model under bias

Using the bosonic numerical renormalization group method, we studied the equilibrium dynamical correlation function C（ω） of the spin operator σz for the biased sub-Ohmic spin-boson model. The small-ω behavior C（ω） ∝ ω～s is found to be universal and independent of the bias ε and the coupling strength α（except at the quantum critical point α = αc and ε = 0）. Our NRG data also show C（ω） ∝ χ～2ω～s for a wide range of parameters, including the biased strong coupling regime（ε = 0 and α 〉 αc）, supporting the general validity of the Shiba relation. Close to the quantum critical point αc,the dependence of C（ω） on α and ε is understood in terms of the competition between ε and the crossover energy scale ω0^＊of the unbiased case. C（ω） is stable with respect to ε for ε《ε^＊. For ε 》ε^＊, it is suppressed by ε in the low frequency regime. We establish that ε^＊∝（ω0^＊）^1/θ holds for all sub-Ohmic regime 0≤s 〈 1, with θ = 2/（3s） for 0 〈 s≤1/2 and θ = 2/（1 ＋ s） for 1/2 〈 s 〈 1. The variation of C（ω） with α and ε is summarized into a crossover phase diagram on the α–ε plane.

Dynamical correlation functions of the quadratic coupling spin-Boson model

The spin-boson model with quadratic coupling is studied using the bosonic numerical renormalization group method.We focus on the dynamical auto-correlation functions CO（ω）, with the operator taken as σx, σz, and X, respectively. In the weak-coupling regime α 〈 αc, these functions show power law ω-dependence in the small frequency limit, with the powers 1 ＋ 2s, 1 ＋ 2s, and s, respectively. At the critical point α = αc of the boson-unstable quantum phase transition, the critical exponents yO of these correlation functions are obtained as yσx= yσz= 1-2s and yX=-s, respectively. Here s is the bath index and X is the boson displacement operator. Close to the spin flip point, the high frequency peak of Cσx（ω） is broadened significantly and the line shape changes qualitatively, showing enhanced dephasing at the spin flip point.

Equilibrium dynamics of the sub-ohmic spin-boson model at finite temperature

We use the full-density matrix numerical renormalization group method to calculate the equilibrium dynamical correlation function C(ω) of the spin operator σ_(z) at finite temperature for the sub-ohmic spin-boson model.A peak is observed at the frequency ω_(T)~T in the curve of C(ω).The curve merges with the zero-temperature C(ω) in ω>>ω_(T) and deviates significantly from the zero-temperature curve in ω<<ω_(T).

Dynamic propagation problems concerning surfaces of asymmetrical mode III crack subjected to moving loads

With the theory of complex functions, dynamic propagation problems concerning surfaces of asymmetrical mode Ⅲ crack subjected to moving loads are investigated. General representations of analytical solutions are obtained with self-similar functions. The problems can be easily converted into Riemann-Hilbert problems using this technique. Analytical solutions to stress, displacement and dynamic stress intensity factor under constant and unit-step moving loads on the surfaces of asymmetrical extension crack, respectively, are obtained. By applying these solutions, together with the superposition principle, solutions of discretionarily intricate problems can be found.

DYNAMIC OBSERVATION OF THYROID FUNCTION IN PATIENTS WITH APLASTIC ANEMIA

Accelerating cell growth is one of the functions of thyroid hormone. In the absence or lack of this hormone, hematopoietic disorder may occur. Dynamic observation of thyroid function in aplastic anemia (AA) state has not been reported yet.

Solving the Inverse Problems of Wave Equation by a Boundary Functional Method

The inverse problems of wave equation to recover unknown space-time dependent functions of wave speed and wave source are solved in this paper, without needing of initial conditions and no internal measurement of data being required. After a homogenization technique, a sequence of spatial boundary functions at least the fourth-order polynomials are derived, which satisfy the homogeneous boundary conditions. The boundary functions and the zero element constitute a linear space, and then a new boundary functional is proved in the linear space, of which the energy is preserved for each dynamic energetic boundary function. The linear systems and iterative algorithms used to recover unknown wave speed and wave source functions with the dynamic energetic boundary functions as bases are developed, which converge fast at each time step. The input data are parsimonious, merely the measured boundary strains and the boundary values and slopes of unknown functions to be recovered. The accuracy and robustness of present methods are confirmed by comparing exact solutions with estimated results under large noises up to 20%.

Pressure Effect on Elastic and Lattice Dynamic Properties of Beryllium Selenide from First Principles

The lattice dynamic, elastic, and thermodynamic properties of Be Se were investigated with first principles calculations. The phase transition pressure from the zinc blende（B3） to the nickel arsenide（B8） structure of Be Se was determined. The elastic stability analysis suggests that the B3 structure Be Se is mechanically stable in the applied pressure range of 0-50 GPa. Our lattice dynamic calculations show that the B3 structure is lattice dynamically stable under high pressure. Within the quasiharmonic approximation, the thermodynamic properties including the constant volume heat capacity and constant pressure heat capacity are predicted.

Dynamic changes of cellular immune function and individualized adjustments of immunosup-pressant for the management of severe infection after liver transplantation

Objective To explore the dynamic changes of the cellular immune function in severe infection after liver transplantation,and to guide the individualized immunology adjustment. Methods 378 cases of liver transplantation were analyzed retrospectively. Seventy - four cases ( infection group) suffered serious infection,including 54 cases cured ( cure group) ,20 cases died (

从语境分析看动态对等论的局限性

Dynamic Equivalence is a concept introduced by Nida(1964) in the context of Bible translation. It has been widely accepted in the field of translation throughout the world but also been questioned by some scholars. Can the theory of dynamic equivalence be applied to all kinds of translation? The present paper tries to find an answer to the question through an analysis of a C/E translation on the basis of Halliday’s theory. [

Multiscale modeling of electrolytes in porous electrode:From equilibrium structure to non-equilibrium transport

Understanding the mechanisms and properties of various transport processes in the electrolyte,porous electrode,and at the interface between electrode and electrolyte plays a crucial role in guiding the improvement of electrolytes,materials and microstructures of electrode.Nanoscale equilibrium properties and nonequilibrium ion transport are substantially different to that in the bulk,which are difficult to observe from experiments directly.In this paper,we introduce equilibrium and no-equilibrium thermodynamics for electrolyte in porous electrodes or electrolyte-electrode interface.The equilibrium properties of electrical double layer(EDL)including the EDL structure and capacitance are discussed.In addition,classical non-equilibrium thermodynamic theory is introduced to help us understand the coupling effect of different transport processes.We also review the recent studies of nonequilibrium ion transport in porous electrode by molecular and continuum methods,among these methods,dynamic density functional theory(DDFT)shows tremendous potential as its high efficiency and high accuracy.Moreover,some opportunities for future development and application of the non-equilibrium thermodynamics in electrochemical system are prospected.

An algorithm for moving target detection in IR image based on grayscale distribution and kernel function

A fast algorithm based on the grayscale distribution of infrared target and the weighted kernel function was proposed for the moving target detection(MTD) in dynamic scene of image series. This algorithm is used to deal with issues like the large computational complexity, the fluctuation of grayscale, and the noise in infrared images. Four characteristic points were selected by analyzing the grayscale distribution in infrared image, of which the series was quickly matched with an affine transformation model. The image was then divided into 32×32 squares and the gray-weighted kernel(GWK) for each square was calculated. At last, the MTD was carried out according to the variation of the four GWKs. The results indicate that the MTD can be achieved in real time using the algorithm with the fluctuations of grayscale and noise can be effectively suppressed. The detection probability is greater than 90% with the false alarm rate lower than 5% when the calculation time is less than 40 ms.