AIM To investigate the effect of Fructus Aurantii Immaturus (FAI) on the small intestinal electric activity. METHODS Effect of FAI was observed by using the computerized electrophysiologic method with migrating myo...AIM To investigate the effect of Fructus Aurantii Immaturus (FAI) on the small intestinal electric activity. METHODS Effect of FAI was observed by using the computerized electrophysiologic method with migrating myoelectric complex (MMC) as a criterion. 100% FAI concentrated solution was given to fasted, healthy and conscious dogs by gastrostogavage, and as soon as the effect on electric activity of small intestine appeared, atropine was injected intramuscularly. RESULTS The enhancing action of FAI could be inhibited significantly by atropine, an antagonist of cholinergic receptor. It is shown that both the number of spike burst per cluster and the number of spike per minute in the phase Ⅱ and Ⅲ and general cycle were decreased ( P <0 01) although the duration of phase Ⅱ and general cycle were prolonged. CONCLUSION The effect of FAI might be related to muscarinic receptor.展开更多
文摘AIM To investigate the effect of Fructus Aurantii Immaturus (FAI) on the small intestinal electric activity. METHODS Effect of FAI was observed by using the computerized electrophysiologic method with migrating myoelectric complex (MMC) as a criterion. 100% FAI concentrated solution was given to fasted, healthy and conscious dogs by gastrostogavage, and as soon as the effect on electric activity of small intestine appeared, atropine was injected intramuscularly. RESULTS The enhancing action of FAI could be inhibited significantly by atropine, an antagonist of cholinergic receptor. It is shown that both the number of spike burst per cluster and the number of spike per minute in the phase Ⅱ and Ⅲ and general cycle were decreased ( P <0 01) although the duration of phase Ⅱ and general cycle were prolonged. CONCLUSION The effect of FAI might be related to muscarinic receptor.
