目的:对比术中应用吲哚青绿与亮蓝辅助内界膜剥除对特发性黄斑裂孔术后临床疗效的影响。方法:搜集世界范围内应用吲哚青绿和亮蓝辅助内界膜剥除治疗特发性黄斑裂孔的临床对照试验的英文及中文文献。计算机检索PubMed,Ovid,Scinece Direc...目的:对比术中应用吲哚青绿与亮蓝辅助内界膜剥除对特发性黄斑裂孔术后临床疗效的影响。方法:搜集世界范围内应用吲哚青绿和亮蓝辅助内界膜剥除治疗特发性黄斑裂孔的临床对照试验的英文及中文文献。计算机检索PubMed,Ovid,Scinece Direct,NGC,EBSCO,EMBASE,CNKI,,CBM数据库。由两位系统评价员做独立文献筛查、质量评价和资料提取,并交叉核对,不同意见时经过讨论或请第三者裁决。使用统计软件Rev Man 5.3完成Meta分析。结果:经筛选最后纳入7篇文献,均是以应用吲哚青绿对比亮蓝辅助内界膜剥除治疗特发性黄斑裂孔的临床对照试验,包括受试患者598例,通过比较术后3个主要临床指标:最佳矫正视力,裂孔闭合率和术后并发症,发现亮蓝辅助内界膜剥除组的术后6mo最佳矫正视力高于吲哚青绿组,差别有统计学意义[Z=2.10(P=0.04),OR=0.10,95%CI(0.01,0.19)];在术后裂孔闭合率和并发症方面,两组比较无明显差别(P>0.05)。结论:亮蓝辅助内界膜剥除治疗特发性黄斑裂孔术后短期内视力恢复快,优于吲哚青绿,是较理想的内界膜染色剂。建议进行大样本、长期随访的高质量临床试验,提供更佳的循证医学证据。展开更多
The paper reviews the most consequential defects and rectification of traditional mathematics and its foundations. While this work is only the tip of the iceberg, so to speak, it gives us a totally different picture o...The paper reviews the most consequential defects and rectification of traditional mathematics and its foundations. While this work is only the tip of the iceberg, so to speak, it gives us a totally different picture of mathematics from what we have known for a long time. This journey started with two teasers posted in SciMath in 1997: 1) The equation 1 = 0.99… does not make sense. 2) The concept ?does not exist. The first statement sparked a debate that raged over a decade. Both statements generated a series of publications that continues to grow to this day. Among the new findings are: 3) There does not exist nondenumerable set. 4) There does not exist non-measurable set. 5) Cantor’s diagonal method is flawed. 6) The real numbers are discrete and countable. 7) Formal logic does not apply to mathematics. The unfinished debate between logicism, intuitionism-constructivism and formalism is resolved. The resolution is the constructivist foundations of mathematics with a summary of all the rectification undertaken in 2015, 2016 and in this paper. The extensions of the constructivist real number system include the complex vector plane and transcendental functions. Two important results in the 2015 are noted: The solution and resolution of Hilbert’s 23 problems that includes the resolution of Fermat’s last theorem and proof Goldbach’s conjecture.展开更多
文摘目的:对比术中应用吲哚青绿与亮蓝辅助内界膜剥除对特发性黄斑裂孔术后临床疗效的影响。方法:搜集世界范围内应用吲哚青绿和亮蓝辅助内界膜剥除治疗特发性黄斑裂孔的临床对照试验的英文及中文文献。计算机检索PubMed,Ovid,Scinece Direct,NGC,EBSCO,EMBASE,CNKI,,CBM数据库。由两位系统评价员做独立文献筛查、质量评价和资料提取,并交叉核对,不同意见时经过讨论或请第三者裁决。使用统计软件Rev Man 5.3完成Meta分析。结果:经筛选最后纳入7篇文献,均是以应用吲哚青绿对比亮蓝辅助内界膜剥除治疗特发性黄斑裂孔的临床对照试验,包括受试患者598例,通过比较术后3个主要临床指标:最佳矫正视力,裂孔闭合率和术后并发症,发现亮蓝辅助内界膜剥除组的术后6mo最佳矫正视力高于吲哚青绿组,差别有统计学意义[Z=2.10(P=0.04),OR=0.10,95%CI(0.01,0.19)];在术后裂孔闭合率和并发症方面,两组比较无明显差别(P>0.05)。结论:亮蓝辅助内界膜剥除治疗特发性黄斑裂孔术后短期内视力恢复快,优于吲哚青绿,是较理想的内界膜染色剂。建议进行大样本、长期随访的高质量临床试验,提供更佳的循证医学证据。
文摘The paper reviews the most consequential defects and rectification of traditional mathematics and its foundations. While this work is only the tip of the iceberg, so to speak, it gives us a totally different picture of mathematics from what we have known for a long time. This journey started with two teasers posted in SciMath in 1997: 1) The equation 1 = 0.99… does not make sense. 2) The concept ?does not exist. The first statement sparked a debate that raged over a decade. Both statements generated a series of publications that continues to grow to this day. Among the new findings are: 3) There does not exist nondenumerable set. 4) There does not exist non-measurable set. 5) Cantor’s diagonal method is flawed. 6) The real numbers are discrete and countable. 7) Formal logic does not apply to mathematics. The unfinished debate between logicism, intuitionism-constructivism and formalism is resolved. The resolution is the constructivist foundations of mathematics with a summary of all the rectification undertaken in 2015, 2016 and in this paper. The extensions of the constructivist real number system include the complex vector plane and transcendental functions. Two important results in the 2015 are noted: The solution and resolution of Hilbert’s 23 problems that includes the resolution of Fermat’s last theorem and proof Goldbach’s conjecture.
