General anesthetic agents induce neurotoxicity through oligodendrocytes in the developing brain

General anesthetic agents can impact brain function through interactions with neurons and their effects on glial cells.Oligodendrocytes perform essential roles in the central nervous system,including myelin sheath formation,axonal metabolism,and neuroplasticity regulation.They are particularly vulnerable to the effects of general anesthetic agents resulting in impaired proliferation,differentiation,and apoptosis.Neurologists are increasingly interested in the effects of general anesthetic agents on oligodendrocytes.These agents not only act on the surface receptors of oligodendrocytes to elicit neuroinflammation through modulation of signaling pathways,but also disrupt metabolic processes and alter the expression of genes involved in oligodendrocyte development and function.In this review,we summarize the effects of general anesthetic agents on oligodendrocytes.We anticipate that future research will continue to explore these effects and develop strategies to decrease the incidence of adverse reactions associated with the use of general anesthetic agents.

General Relativity and the Tully-Fisher Relation for Rotating Galaxies

The flat limit of rotational velocity (vφ) approximately equal to the “edge”-velocity of a galaxy is related to the baryonic mass (MB) via the T-F relationship with n ≈ 4. We explore the connection between mass and the limiting velocity in the framework of general relativity (GR) using the Weyl metric for axially-symmetric galaxies that are supported entirely by their rotational motion. While for small distances from the center, the Newtonian description is accurate as one moves beyond the (baryonic) edge of the galaxy, Lenz’s law and non-linearity of the gravitational field inherent in GR not only lead to a flat velocity (obviating its Keplerian fall), but also provide its tight log-log relationship with the enclosed (baryonic) mass.

Bar Presence in Local Galaxies:Dependence on Morphology in Field Galaxies

We analyzed the fractions of barred galaxies in the local Universe using a volume-limited sample of galaxies from the Sloan Digital Sky Survey Data Release 3.We examined 116 field galaxies with redshifts between 0.0207 and 0.030,using r and z-band images.Overall,the bar fraction was 26%in the r-band and 19%in the z-band.Fo distinct morphological groups,barred spiral galaxies had fractions of 33%in the r-band and 22%in the z-band while barred lenticular galaxies had 25%in the r-band and 12%in the z-band.We observed that the bar fraction in spiral galaxies increases for stellar masses log(M*/M_(⊙))>10.5 and for galaxies with red colors(u-r)>2.0Additionally,most barred galaxies have a bulge-to-total ratio B/T≤0.2.Our results indicate that the bar fraction i more dependent on internal morphology than on the galaxy environment.

Extended wet sieving method for determination of complete particle size distribution of general soils

The traditional standard wet sieving method uses steel sieves with aperture?0.063 mm and can only determine the particle size distribution(PSD)of gravel and sand in general soil.This paper extends the traditional method and presents an extended wet sieving method.The extended method uses both the steel sieves and the nylon filter cloth sieves.The apertures of the cloth sieves are smaller than 0.063 mm and equal 0.048 mm,0.038 mm,0.014 mm,0.012 mm,0.0063 mm,0.004 mm,0.003 mm,0.002 mm,and 0.001 mm,respectively.The extended method uses five steps to separate the general soil into many material sub-groups of gravel,sand,silt and clay with known particle size ranges.The complete PSD of the general soil is then calculated from the dry masses of the individual material sub-groups.The extended method is demonstrated with a general soil of completely decomposed granite(CDG)in Hong Kong,China.The silt and clay materials with different particle size ranges are further examined,checked and verified using stereomicroscopic observation,physical and chemical property tests.The results further confirm the correctness of the extended wet sieving method.

General anesthetic agents induce neurotoxicity through astrocytes

Neuroscientists have recognized the importance of astrocytes in regulating neurological function and their influence on the release of glial transmitters.Few studies,however,have focused on the effects of general anesthetic agents on neuroglia or astrocytes.Astrocytes can also be an important target of general anesthetic agents as they exert not only sedative,analgesic,and amnesic effects but also mediate general anesthetic-induced neurotoxicity and postoperative cognitive dysfunction.Here,we analyzed recent advances in understanding the mechanism of general anesthetic agents on astrocytes,and found that exposure to general anesthetic agents will destroy the morphology and proliferation of astrocytes,in addition to acting on the receptors on their surface,which not only affect Ca^(2+)signaling,inhibit the release of brain-derived neurotrophic factor and lactate from astrocytes,but are even involved in the regulation of the pro-and anti-inflammatory processes of astrocytes.These would obviously affect the communication between astrocytes as well as between astrocytes and neighboring neurons,other neuroglia,and vascular cells.In this review,we summarize how general anesthetic agents act on neurons via astrocytes,and explore potential mechanisms of action of general anesthetic agents on the nervous system.We hope that this review will provide a new direction for mitigating the neurotoxicity of general anesthetic agents.

Four Late-type Galaxies with Double Radio Lobes and Properties of Such Galaxies

The triggering mechanism for radio lobes from late-type galaxies is not fully understood.More samples are desired for a thorough investigation and statistics.By utilizing the optical data from the newly released Dark Energy Spectroscopic Instrument imaging surveys and the radio sources from the NRAO VLA Sky Survey and the Faint Images of the Radio Sky at Twenty-centimeter,we identify four Late-type Galaxies with double Radio Lobes(La GRLs):J0217-3645,J0947+6220,J1412+3723 and J1736+5108.Including previously known La GRLs,we confirm the correlation between radio power P_(1.4GHz)and stellar mass M_(*)of host galaxies.Most(25/35)La GRLs belong to the blue cloud galaxies,while the newly identified cases in this work are located within the region of the red sequence.We find a clear correlation between the differential radio power,i.e.,the offset from the P_(1.4GHz)-M_(*)relation,and the galaxy color,indicating that bluer galaxies at a fixed M_(*)tend to host more powerful radio lobes.Furthermore,the majority(31/36)of La GRLs are either located in a galaxy group or displaying a disturbed morphology.We suggest that all of the galaxy mass,color and surrounding environment could play important roles in triggering radio lobes in late-type galaxies.

Stellar Populations of AGN-host Dwarf Galaxies Selected with Different Methods

In this paper we investigate the stellar populations and star formation histories of 235 active galactic nucleus(AGN)-host dwarf galaxies,consisting of four samples identified separately with different methods(i.e.,radio,X-ray,mid-IR and variability),utilizing the synthesis code STARLIGHT and spectra from the Sloan Digital Sky Survey Data Release 8.Our results show that the variability sample is the oldest,while the mid-IR sample is the youngest,for which the luminosity at 4020?is dominated(>50%)by the young population(t<10~8yr).The light-weighted mean stellar age of the whole sample is in general about 0.7 dex younger than the optical sample studied in Cai et al.We compare the population results between fitting models with and without a power-law(PL)component and find that the neglect of a PL component would lead to an under-and over-estimation by 0.2 and0.1 dex for the light-and mass-weighted mean stellar age,respectively,for our sample of dwarf galaxies,which has a mean fractional contribution of~16%from the AGN.In addition,we obtain further evidence for a possible suppression of star formation in the host galaxy by the central AGN.We also find that there exists an anticorrelation between the extinction-corrected[O III]luminosity and light-weighted mean stellar age,confirming our previous finding that there is a physical connection between AGN and star-forming activities in AGN-host dwarfs.

Morphological Classification of Infrared Galaxies Based on WISE

This study introduces a novel convolutional neural network,the WISE Galaxy Classification Network(WGC),for classifying spiral and elliptical galaxies using Wide-field Infrared Survey Explorer(WISE)images.WGC attains an accuracy of 89.03%,surpassing the combined use of K-means or SVM with the Color-Color method in more accurately identifying galaxy morphologies.The enhanced variant,WGC_mag,integrates magnitude parameters with image features,further boosting the accuracy to 89.89%.The research also delves into the criteria for galaxy classification,discovering that WGC primarily categorizes dust-rich images as elliptical galaxies,corresponding to their lower star formation rates,and classifies less dusty images as spiral galaxies.The paper explores the consistency and complementarity of WISE infrared images with SDSS optical images in galaxy morphology classification.The SDSS Galaxy Classification Network(SGC),trained on SDSS images,achieved an accuracy of 94.64%.The accuracy reached 99.30% when predictions from SGC and WGC were consistent.Leveraging the complementarity of features in WISE and SDSS images,a novel variant of a classifier,namely the Multi-band Galaxy Morphology Integrated Classifier,has been developed.This classifier elevates the overall prediction accuracy to 95.39%.Lastly,the versatility of WGC was validated in other data sets.On the HyperLEDA data set,the distinction between elliptical galaxies and Sc,Scd and Sd spiral galaxies was most pronounced,achieving an accuracy of 90%,surpassing the classification results of the Galaxy Zoo 2 labeled WISE data set.This research not only demonstrates the effectiveness of WISE images in galaxy morphology classification but also represents an attempt to integrate multi-band astronomical data to enhance understanding of galaxy structures and evolution.

Observation of HⅠaround three Satellite Galaxies of M31 with FAST:AndromedaⅡ,NGC 205,and NGC 185

With the exceptional sensitivity of the Five-hundred-meter Aperture Spherical radio Telescope,we conducted observations of the neutral hydrogen(HⅠ)in the circumgalactic medium of Andromeda’s(M31)satellite galaxies,specifically AndromedaⅡ,NGC 205,and NGC 185.Initially,three drift scans were executed for these satellites,with a detection limit of 4×10^(18)cm^(-2)(approximately 1.88×10^(3)M_Θof HⅠmass),followed by a more in-depth scan of a specific region.We discovered a C-shaped HⅠarc structure sharing a position and line-of-sight velocity similar to a stellar ring structure around AndromedaⅡ,hinting at a potential connection with AndromedaⅡ.In the context of NGC 205,we identified two mass concentrations in the northeast direction,which could be indicative of tidal streams resulting from the interaction between this galaxy and M31.These new lumps discovered could be very helpful in solving the missing interstellar medium problem for NGC 205.Observations regarding NGC 185are consistent with previous studies,and we did not detect any additional HⅠmaterial around this galaxy.These observational results enhance our understanding of the evolution of these satellite galaxies and provide insight into their historical interactions with the galaxy M31.

A Dark Matter Theory by Quantum Gravitation for Galaxies and Clusters

This paper develops an original theory of dark matter in the current ΛCDM framework, whose main hypothesis is that DM is generated by the own gravitational field, according to an unknown quantum gravitational phenomenon. This work is the best version of the theory, which I have been developing and publishing since 2014. The hypothesis of DM by quantum gravitation, DMbQG hereafter, has two main consequences: the first one is that the law of DM generation has to be the same, in the halo region, for all the galaxies and the second one is that the haloes are unbounded, so the total DM goes up without limit as the gravitational field is unbounded as well. The first one consequence is backed by the fact that M31 and MW has a fitted function with the same power exponent for the rotation curve at the halo region and both giant galaxies are the only ones whose rotation curves at the halo region may be studied with accuracy. This paper is firstly developed all the theory with M31 rotation curve data up to Chapter 9. The most important formula of the theory is the called Direct mass, which calculates the total mass at a specific radius into the halo region. Chapter 10 is dedicated to apply the theory to Milky Way, it is calculated its total mass at different radius into the halo and such results have been validated successfully using the data of masses at different radius published by two researcher teams. In Chapter 11, it is calculated the direct mass for the Local Group, and it is shown how the DMbQG theory is able to calculate the total mass at 770 kpc, that the dynamical methods estimate to be 5×1012MΘ. In Chapter 12, it is shown a method to estimate the Direct mass formula for a cluster of galaxies, using only its virial mass and virial radius. By this method, it is estimated the parameter a2 of the Local Group, which match with the one calculated in previous chapter by a different method. Also are calculated the parameters a2 associated to Virgo and Coma clusters. In Chapter 13, it is demonstrated how the DE is able to counterbalance the DM at cluster scale, as the Direct mass grows up with the square root of radius whereas the DE grows up with the cubic power. The chapter is an introduction to the DMbQG theory for cluster of galaxies, which has been developed fully by the author in other works. This theory aims to be a powerful method to study DM in the halo region of galaxies and cluster of galaxies and conversely the measures in galaxies and clusters offer the possibility to validate the theory.

Low Surface Brightness Galaxies Selected by Different Model Fitting

We present a study of low surface brightness galaxies(LSBGs) selected by fitting the images for all the galaxies inα.40 SDSS DR7 sample with two kinds of single-component models and two kinds of two-component models(disk+bulge):single exponential,single sersic,exponential+deVaucular(exp+deV),and exponential+sérsic(exp+ser).Under the criteria of the B band disk central surface brightness μ_(0,disk)(B)≥22.5 mag arcsec^(-2) and the axis ratio b/a> 0.3,we selected four none-edge-on LSBG samples from each of the models which contain 1105,1038,207,and 75 galaxies,respectively.There are 756 galaxies in common between LSBGs selected by exponential and sersic models,corresponding to 68.42% of LSBGs selected by the exponential model and 72.83% of LSBGs selected by the sersic model,the rest of the discrepancy is due to the difference in obtaining μ_(0) between the exponential and sersic models.Based on the fitting,in the range of 0.5≤n≤1.5,the relation of μ_(0) from two models can be written as μ_(0,sérsic)-μ_(0,exp)=-1.34(n-1).The LSBGs selected by disk+bulge models(LSBG_(2)comps) are more massive than LSBGs selected by single-component models(LSBG_1comp),and also show a larger disk component.Though the bulges in the majority of our LSBG_(2)comps are not prominent,more than 60% of our LSBG_(2)comps will not be selected if we adopt a single-component model only.We also identified 31 giant low surface brightness galaxies(gLSBGs) from LSBG_(2)comps.They are located at the same region in the color-magnitude diagram as other gLSBGs.After we compared different criteria of gLSBGs selection,we find that for gas-rich LSBGs,M_(*)> 10^(10)M_⊙ is the best to distinguish between gLSBGs and normal LSBGs with bulge.

The Clumpy Structure of Five Star-bursting Dwarf Galaxies in the MaNGA Survey

The star-forming clumps in star-bursting dwarf galaxies provide valuable insights into understanding the evolution of dwarf galaxies.In this paper,we focus on five star-bursting dwarf galaxies featuring off-centered clumps in the Mapping Nearby Galaxies at Apache Point Observatory survey.Using the stellar population synthesis software Fitting Analysis using Differential evolution Optimization,we obtain the spatially resolved distribution of the star formation history,which allows us to construct the g-band images of the five galaxies at different ages.These images can help us to probe the evolution of the morphological structures of these galaxies.While images of a stellar population older than 1 Gyr are typically smooth,images of a stellar population younger than 1 Gyr reveal significant clumps,including multiple clumps which appear at different locations and even different ages.To study the evolutionary connections of these five galaxies to other dwarf galaxies before their star-forming clumps appear,we construct the images of the stellar populations older than three age nodes,and define them to be the images of the"host"galaxies.We find that the properties such as the central surface brightness and the effective radii of the hosts of the five galaxies are in between those of dwarf ellipticals(dEs)and dwarf irregulars(dIrrs),with two clearly more similar to dEs and one more similar to dIrrs.Among the five galaxies,8257-3704 is particularly interesting,as it shows a previous starburst event that is not quite visible from its gri image,but only visible from images of the stellar population at a few hundred million years.The star-forming clump associated with this event may have appeared at around 600 Myr ago and disappeared at around 40 Myr ago.

Cosmological Constraints on Neutrino Masses in Light of JWST Red and Massive Candidate Galaxies

The overabundance of the red and massive candidate galaxies observed by the James Webb Space Telescope(JWST)implies efficient structure formation or large star formation efficiency at high redshift z~10.In the scenario of a low or moderate star formation efficiency,because massive neutrinos tend to suppress the growth of structure of the universe,the JWST observation tightens the upper bound of the neutrino masses.Assuming A cold dark matter cosmology and a star formation efficiency∈[0.05,0.3](flat prior),we perform joint analyses of Planck+JWST and Planck+BAO+JWST,and obtain improved constraints∑m_(ν)<0.196 eV and ∑m_(ν)+<0.111 eV at 95% confidence level,respectively.Based on the above assumptions,the inverted mass ordering,which implies ∑m_(ν)≥0.1 eV,is excluded by Planck+BAO+JWST at 92.7% confidence level.

Universal Scaling Laws in Quantum-Probabilistic Machine Learning by Tensor Network: Toward Interpreting Representation and Generalization Powers

The interpretation of representations and generalization powers has been a long-standing challenge in the fields of machine learning(ML)and artificial intelligence.This study contributes to understanding the emergence of universal scaling laws in quantum-probabilistic ML.We consider the generative tensor network(GTN)in the form of a matrix-product state as an example and show that with an untrained GTN(such as a random TN state),the negative logarithmic likelihood(NLL)L generally increases linearly with the number of features M,that is,L≃kM+const.This is a consequence of the so-called“catastrophe of orthogonality,”which states that quantum many-body states tend to become exponentially orthogonal to each other as M increases.This study reveals that,while gaining information through training,the linear-scaling law is suppressed by a negative quadratic correction,leading to L≃βM−αM^(2)+const.The scaling coefficients exhibit logarithmic relationships with the number of training samples and quantum channelsχ.The emergence of a quadratic correction term in the NLL for the testing(training)set can be regarded as evidence of the generalization(representation)power of the GTN.Over-parameterization can be identified by the deviation in the values ofαbetween the training and testing sets while increasingχ.We further investigate how orthogonality in the quantum-feature map relates to the satisfaction of quantum-probabilistic interpretation and the representation and generalization powers of the GTN.Unveiling universal scaling laws in quantum-probabilistic ML would be a valuable step toward establishing a white-box ML scheme interpreted within the quantum-probabilistic framework.

Comparing the Structural Parameters of the Milky Way to Other Spiral Galaxies

The structural parameters of a galaxy can be used to gain insight into its formation and evolution history.In this paper,we strive to compare the Milky Way’s structural parameters to other,primarily edge-on,spiral galaxies in order to determine how our Galaxy measures up to the Local Universe.For our comparison,we use the galaxy structural parameters gathered from a variety of literature sources in the optical and near-infrared wave bands.We compare the scale length,scale height,and disk flatness for both the thin and thick disks,the thick-to-thin disk mass ratio,the bulge-to-total luminosity ratio,and the mean pitch angle of the Milky Way’s spiral arms to those in other galaxies.We conclude that many of the Milky Way’s structural parameters are largely ordinary and typical of spiral galaxies in the Local Universe,though the Galaxy’s thick disk appears to be appreciably thinner and less extended than expected from zoom-in cosmological simulations of Milky Way-mass galaxies with a significant contribution of galaxy mergers involving satellite galaxies.

Recent Developments on the H_(I)Gas of Low-Redshift Galaxies Seen by the 21 cm Emission Lines

As a major interstellar medium,the atomic neutral hydrogen(H_(I))plays an important role in the galaxy evolution.It provides the ingredient for star formation,and sensitively traces the internal processes and external perturbations influencing the galaxy.With the beginning of many new radio telescopes and surveys,H_(I)may make a more significant contribution to the understanding of galaxies in the near future.This review discusses the major development of the 21 cm emission-line H_(I)observations and studies in the past few years,including its scaling relations with other galaxy properties,its kinematics and structures,its role in environmental studies,and its constraints on hydrodynamical simulations.The local-Universe H_(I)scaling relations of stellar-massselected samples extend smoothly to 10^(9)M⊙stellar mass,with a tentative evolution to the redshift of∼0.1.The development of measurement techniques enables better estimations of H_(I)non-circular motion,dispersion,and thickness,and new observations revealed extended or extra-planar H_(I)structures,both helpfully constraining the gas accretion,stellar feedback,and star formation processes of galaxy evolution models.H_(I)is very useful for tracing the satellite evolution in dense environments,the studies of which would benefit from ongoing blind H_(I)surveys.Though simulations still cannot fully reproduce H_(I)gas properties,they help to understand the role of possible factors in regulating H_(I)properties.

Formation of Superthin Galaxies in IllustrisTNG

Superthin galaxies are observed to have stellar disks with extremely small minor-to-major axis ratios.In this work,we investigate the formation of superthin galaxies in the TNG100 simulation.We trace the merger history and investigate the evolution of galaxy properties of a selected sample of superthin galaxies and a control sample of galaxies that share the same joint probability distribution in the stellar-mass and color diagram.Through making comparisons between the two galaxy samples,we find that present-day superthin galaxies had similar morphologies as the control sample counterparts at higher redshifts,but have developed extended flat“superthin”morphologies since z~1.During this latter evolution stage,superthin galaxies undergo an overwhelmingly higher frequency of prograde mergers(with orbit-spin angleθ_(orb)≤40°).Accordingly the spins of their dark matter halos have grown significantly and become noticeably higher than those of their normal disk counterparts.This further results in the buildup of their stellar disks at larger distances much beyond the regimes of normal disk galaxies.We also discuss the formation scenario of those superthin galaxies that live in larger dark matter halos as satellite galaxies therein.

The Mass Assembly History for Galaxies with MaNGA

How galaxies assemble masses through their own star formation or interaction with the external environment is still an important topic in the field of galaxy formation and evolution.We use Value Added Catalogs with galaxy features that are spatially and temporally resolved from Sloan Digital Sky Survey Data Release 17 to investigate the mass growth histories of early-type galaxies(ETGs)and late-type galaxies(LTGs).We find that the mass growth of ETGs is earlier than that of LTGs for massive galaxies(M_(*)>10^(10)M_⊙),while low-mass(M_(*)≤10^(10)M_⊙)ETGs have statistically similar mass assembly histories as low-mass LTGs.The stellar metallicity of all massive galaxies shows a negative gradient and basically does not change with time.However,in low-mass galaxies,the stellar metallicity gradient of elliptical galaxies is negative,and the stellar metallicity gradient of lenticular and spiral galaxies evolves from positive to negative.ETGs are not all in a high-density environment,but exhibit mass dependence.As the tidal strength increases,the star formation rate of low-mass ETGs rapidly decreases.These results support a picture where massive galaxies exhibit inside-out quenching mode,while low-mass galaxies show outside-in quenching mode.Environmental effects play an important role in regulating the mass assembly histories of low-mass ETGs.

Quantifying the Tension between Cosmological Models and JWST Red Candidate Massive Galaxies

We develop a Python tool to estimate the tail distribution of the number of dark matter halos beyond a mass threshold and in a given volume in a light-cone.The code is based on the extended Press-Schechter model and is computationally efficient,typically taking a few seconds on a personal laptop for a given set of cosmological parameters.The high efficiency of the code allows a quick estimation of the tension between cosmological models and the red candidate massive galaxies released by the James Webb Space Telescope,as well as scanning the theory space with the Markov Chain Monte Carlo method.As an example application,we use the tool to study the cosmological implication of the candidate galaxies presented in Labbéet al.The standard Λcold dark matter(ΛCDM)model is well consistent with the data if the star formation efficiency can reach~0.3 at high redshift.For a low star formation efficiency ε~0.1,theΛCDM model is disfavored at~2σ-3σconfidence level.

On the Relation Between Symmetry of Radio Galaxies and Their Physical Parameters

Gravity as a fundamental force plays a dominant role in the formation and evolution of cosmic objects and leaves its effect in the emergence of symmetric and asymmetric structures.Thus,analyzing the symmetry criteria allows us to uncover mechanisms behind the gravity interaction and understand the underlying physical processes that contribute to the formation of large-scale structures such as galaxies.We use a segmentation process using intensity thresholding and the k-means clustering algorithm to analyze radio galaxy images.We employ a symmetry criterion and explore the relation between morphological symmetry in radio maps and host galaxy properties.Optical properties(stellar mass,black hole mass,optical size(R_(50)),concentration,stellar mass surface density(μ_(50)),and stellar age)and radio properties(radio flux density,radio luminosity,and radio size)are considered.We found that there is a correlation between symmetry and radio size,indicating larger radio sources have smaller symmetry indices.Therefore,size of radio sources should be considered in any investigation of symmetry.Weak correlations are also observed with other properties,such as R_(50)for FRI galaxies and stellar age.We compare the symmetry differences between FRI and FRII radio galaxies.FRII galaxies show higher symmetry in 1.4 GHz and 150 MHz maps.Investigating the influence of radio source sizes,we discovered that this result is independent of the sizes of radio sources.These findings contribute to our understanding of the morphological properties and analyses of radio galaxies.