Gates joint locally connected network for accurate and robust reconstruction in optical molecular tomography

Optical molecular tomography(OMT)is a potential pre-clinical molecular imaging technique with applications in a variety of biomedical areas,which can provide non-invasive quantitative three-dimensional(3D)information regarding tumor distribution in living animals.The construction of optical transmission models and the application of reconstruction algorithms in traditional model-based reconstruction processes have affected the reconstruction results,resulting in problems such as low accuracy,poor robustness,and long-time consumption.Here,a gates joint locally connected network(GLCN)method is proposed by establishing the mapping relationship between the inside source distribution and the photon density on surface directly,thus avoiding the extra time consumption caused by iteration and the reconstruction errors caused by model inaccuracy.Moreover,gates module was composed of the concatenation and multiplication operators of three different gates.It was embedded into the network aiming at remembering input surface photon density over a period and allowing the network to capture neurons connected to the true source selectively by controlling three different gates.To evaluate the performance of the proposed method,numerical simulations were conducted,whose results demonstrated good performance in terms of reconstruction positioning accuracy and robustness.

Recent progress in stimuli-responsive DNA-based logic gates:Design,working principles and biological applications

Stimuli-responsive DNA-based logic gates have emerged as a promising field at the intersection of synthetic biology and nanotechnology.These gates exploit the unique properties of DNA molecules to perform programmable computational operations in response to specific stimuli.This review provides a comprehensive overview of recent advancements in the design,working principles,and applications of stimuli-responsive DNA-based logic gates.The progress made in developing various types of logic gates triggered by metal ions,pH,oligonucleotides,small molecules,proteins,and light is highlighted.The applications of these logic gates in imaging and biosensing,drug delivery,synthetic biology and molecular computing are discussed.This review underscores the significant contributions and future prospects of stimuli-responsive DNA-based logic gates in advancing the field of nanotechnology.

Study of a Hydraulic Jump in an Asymmetric Trapezoidal Channel with Different Sluice Gates

In this study,the main properties of the hydraulic jump in an asymmetric trapezoidal flume are analyzed experimentally,including the so-called sequent depths,characteristic lengths,and efficiency.In particular,an asymmetric trapezoidal flume with a length of 7 m and a width of 0.304 m is considered,with the bottom of the flume transversely inclined at an angle of m=0.296 and vertical lateral sides.The corresponding inflow Froude number is allowed to range in the interval(1.40<F1<6.11).The properties of this jump are compared to those of hydraulic jumps in channels with other types of cross-sections.A relationship for calculating hydraulic jump efficiency is proposed for the considered flume.For F1>5,the hydraulic jump is found to be more effective than that occurring in triangular and symmetric trapezoidal channels.Also,when■mes>8 and■>5,the hydraulic jump in the asymmetrical trapezoidal channel downstream of a parallelogram sluice gate is completely formed as opposed to the situation where a triangular sluice is considered.

Gates法计算的GFR在单侧肾积水患者肾小球滤过功能评价中的应用

目的探讨Gates法计算的肾小球滤过率(GFR)对单侧肾积水患者肾小球滤过功能评估的价值。方法选择经B超检查确诊为单侧肾积水的患者176例(轻度积水组21例、中度积水组33例、重度积水组122例),同期选取泌尿系统及GFR均正常的肾移植供体捐献者22例(正常对照组)。两组均接受99mTc-DTPA肾动态显像检查,用Gates法计算患肾、健肾、双肾GFR值,根据单肾GFR将患者肾功能划分为肾功能正常、轻度下降、中度下降、重度下降及肾无功能。结果与正常对照组比较,中、重度积水组患侧肾GFR降低,轻、中、重度积水组健侧肾GFR升高,中、重度积水组双肾GFR降低(P均<0.05)。轻度积水组90.48%的患肾GFR正常,中度积水组63.64%的患肾GFR轻度下降,重度积水组35.25%的患肾GFR重度下降、33.33%的患肾无功能。积水越严重肾功能越差。结论 Gates法计算的单肾、总肾GFR可定量分析单侧肾积水患者肾小球滤过功能,同步评价健侧肾的代偿能力。

Gow-Gates法下牙槽神经阻滞麻醉在下颌阻生第三磨牙拔除术中的麻醉效果研究

目的通过临床随机对照试验的方法评价Gow-Gates法下牙槽神经阻滞麻醉在下颌阻生第三磨牙拔除术中的麻醉有效性和安全性。方法使用左右半口设计,32例患者的左右下颌阻生第三磨牙分别随机采用Gow-Gates法和传统注射法进行下牙槽神经阻滞麻醉,并拔除下颌阻生第三磨牙,记录麻醉效果及不良事件。结果所有患者均完成研究。Gow-Gates法的麻醉成功率为96.9%,传统注射法的麻醉成功率为90.6%,二者的麻醉成功率无统计学差异(P=0.317)。在麻醉程度上,Gow-Gates法麻醉程度为A和B级的比率为96.9%,明显好于传统注射法的78.1%(P=0.034)。Gow-Gates法的回抽出血率明显低于传统注射法(P=0.025),2种注射方法均未出现血肿。结论 Gow-Gates法下牙槽神经阻滞麻醉在下颌阻生第三磨牙拔除术中的麻醉效果好且较为安全,可以作为传统注射法的有效补充。

肾积水对轻中度肾损伤者Gates法GFR的影响

目的了解轻中度肾积水对肾动态显像GFR的影响。方法回顾2010年1～12月51例双血浆法GFR(tGFR)在30～90ml/(1.73m2.min)范围内的肾积水患者的肾动态显像,按照tGFR的大小并结合肾脏疾病的分期标准分成正常对照组[90ml(1.73m2.min)≤tGFR<120ml/(1.73m2.min)],轻度[60ml/(1.73m2.min)≤tGFR<90ml/(1.73m2.min)]和中度[30ml/(1.73m2.min)≤tGFR<60ml/(1.73m2.min)]肾损伤3组,并比较体表面积标准化前后Gates法GFR(gGFR)和tGFR间差异和相关性。结果大多数情况下,gGFR均高于tGFR,二者差值范围-35.1～26.1ml/(1.73m2.min);tGFRBSA和gGFRBSA间差值范围-38.3～26.8ml/(1.73m2.min)。无论轻度和中度肾损伤组,还是整体患者中,BSA标准化均可改善tGFR和gGFR间的相关性。BSA标准化后,中度肾损伤组的相关系数可达到0.634(P=0.020),而轻度肾损伤组和整体患者中仅为0.298(P=0.229)和0.543(P=0.002)。结论体表面积标准化Gates法GFR可提高其与双血浆法间的相关性,但评估肾积水伴轻中度肾损伤患者GFR价值有限,应参考双血浆法的定量结果。

Implementing remote controlled-NOT gates and entanglement swapping via geometric phase gates in ion-trap systems

We propose a scheme for the implementation of remote controlled-NOT gates and entanglement swapping via geometric phase gates in ion-trap systems. The proposed scheme uses the two ground states of the A-type ions as memory instead of the vibrational mode. And the system is robust against the spontaneous radiation and the dephasing.

Realization of adiabatic and diabatic CZ gates in superconducting qubits coupled with a tunable coupler

High fidelity two-qubit gates are fundamental for scaling up the superconducting qubit number.We use two qubits coupled via a frequency-tunable coupler which can adjust the coupling strength,and demonstrate the CZ gate using two different schemes,adiabatic and diabatic methods.The Clifford based randomized benchmarking(RB) method is used to assess and optimize the CZ gate fidelity.The fidelities of adiabatic and diabatic CZ gates are 99.53(8)% and 98.72(2)%,respectively.We also analyze the errors induced by the decoherence.Comparing to 30 ns duration time of adiabatic CZ gate,the duration time of diabatic CZ gate is 19 ns,revealing lower incoherence error rate r’_(incoherent),int=0.0197(5) compared to r_(incoherent,int)=0.0223(3).

基于Attention Gates和R2U-Net的遥感影像建筑物提取方法

针对深度语义分割算法提取遥感影像建筑物时易产生建筑物边缘分割不明确、提取精度不高等问题,该文提出一种基于Attention Gates(AG)和R2U-Net的遥感影像建筑物提取方法(AGR2U-Net)。该方法将R2U-Net模型每一层输出的特征图与其相邻层的特征图输入至改进的AG模型中,得到与输入影像大小一致的特征图,以提高R2U-Net模型的多尺度泛化能力,从而增强该模型对建筑物特征的响应及灵敏度,最终提升遥感影像建筑物提取精度。利用WHU卫星影像数据集和WHU航空影像数据集,对该方法与U-Net、Improved U-Net、SegU-Net和R2U-Net方法进行对比实验验证,结果表明,该方法的交并比、像素准确率和召回率均最高,且提取的建筑物边缘更准确、内部信息更完整、误检和漏检情况更少。

弹丸注射质量对Gates法测定活体肾移植供者GFR的影响

目的探讨高质量弹丸注射对Gates法准确测定活体肾移植供者GFR的重要意义。方法收集在我院核医学科行肾动态显像的102例亲属活体肾移植供者的检查资料,将这102例受检者根据弹丸注射质量分为两组:A组(弹丸注射质量良好)56例,B组(弹丸注射质量欠佳以及不合格)46例。对比两组的年龄、性别、肾脏深度、注入体内放射性计数、分肾GFR、总肾GFR、eGFR差异,并将两组的肾动态显像测定的总肾GFR值与eGFR进行相关性和一致性分析。结果A、B两组的年龄、性别、肾脏深度、注入体内放射性计数、eGFR差异均无统计学意义,而两组的左肾GFR、右肾GFR、总GFR的差异均具有统计学意义。与B组相比,A组的总GFR与eGRF有更好的相关性和一致性。结论高质量弹丸注射对Gates法准确测定活体肾移植供者GFR具有重要意义,弹丸质量不佳将导致测定的GFR偏低。

应用^(99m)Tc-DTPA测定GFR——Gates法

应用^(99m)Tc-DTPA检测肾功能的方法很多,Gates法是以^(99m)Tc-DTPA肾摄取率来计算GFR,它可同时评价总肾功能和分肾功能,并且与临床传统检查的内生肌酐清除率有良好的相关性(r=0.89～0.99).本文简要介绍了Gates法及其有关的γ射线吸收校正、肾脏深度的计算、检测时间的设定等问题.

Controllable all-optical stochastic logic gates and their delay storages based on the cascaded VCSELs with optical-injection

Using the dynamical properties of the polarization bistability that depends on the detuning of the injected light,we propose a novel approach to implement reliable all-optical stochastic logic gates in the cascaded vertical cavity surface emitting lasers（VCSELs） with optical-injection.Here,two logic inputs are encoded in the detuning of the injected light from a tunable CW laser.The logic outputs are decoded from the two orthogonal polarization lights emitted from the optically injected VCSELs.For the same logic inputs,under electro-optic modulation,we perform various digital signal processing（NOT,AND,NAND,XOR,XNOR,OR,NOR） in the all-optical domain by controlling the logic operation of the applied electric field.Also we explore their delay storages by using the mechanism of the generalized chaotic synchronization.To quantify the reliabilities of these logic gates,we further demonstrate their success probabilities.

Tunable Nongeometric Phase Gates for Two Hot Ions via Adiabatic Evolution of Dark States

We propose a scheme for implementing nongeometric phase gates fbr two trapped ions via adiabatic passage of dark states. During the operation, the vibrational mode is only virtually excited, thus the scheme is insensitive to heating. Furthermore, the spontaneous emission is suppressed since the ions are always in the electronic ground states. The scheme is robust against small fluctuations of parameters, and the conditional phase is tunable.

Two-qubit and three-qubit controlled gates with cross-Kerr nonlinearity

Schemes for two-qubit and three-qubit controlled gates based on cross-Kerr nonlinearity are proposed in this paper.The probability of the success of these gates can be increased by quantum nondemolition detectors,which are used to judge which paths the signal photons pass through.These schemes are almost deterministic and require no ancilla photon.The advantages of these gates over the existing ones include less resource consumption and a higher probability of success,which make our schemes more feasible with current technology.

Study of Decoherence of Elementary Gates Implemented in a Chain of Few Nuclear Spins Quantum Computer Model

We study the phenomenon of decoherence during the operation of one qubit transformation, controlled-not (CNOT) and controlled-controlled-not (C2NOT) quantum gates in a quantum computer model formed by a linear chain of three nuclear spins system. We make this study with different type of environments, and we determine the associated decoherence time as a function of the dissipative parameter. We found that the dissipation parameter to get a well defined quantum gates (without significant decoherence) must be within the range of . We also study the behavior of the purity parameter for these gates and different environments and found linear or quadratic decays of this parameter depending on the type of environments.

A High Performance Sub-100nm Nitride/Oxynitride Stack Gate Dielectric CMOS Device with Refractory W/TiN Metal Gates

By complementing the equivalent oxide thickness （EOT） of a 1.7nm nitride/oxynitride （N/O） stack gate dielectric （EOT- 1.7nm） with a W/TiN metal gate electrode,metal gate CMOS devices with sub-100nm gate length are fabricated in China for the first time. The key technologies adopted to restrain SCE and to improve drive ability include a 1.7nm N/O stack gate dielectric, non-CMP planarization technology, a T-type refractory W/TiN metal stack gate electrode, and a novel super steep retrograde channel doping using heavy ion implantation and a double sidewall scheme. Using these optimized key technologies, high performance 95nm metal gate CMOS devices with excellent SCE and good driving ability are fabricated. Under power supply voltages of VDS ± 1.5V and VGS± 1.8V,drive currents of 679μA/μm for nMOS and - 327μA/μm for pMOS are obtained. A subthreshold slope of 84.46mV/dec, DIBL of 34.76mV/V, and Vth of 0.26V for nMOS, and a subthreshold slope of 107.4mV/dec,DIBL of 54.46mV/V, and Vth of 0.27V for pMOS are achieved. These results show that the combined technology has indeed thoroughly eliminated the boron penetration phenomenon and polysilicon depletion effect ,effectively reduced gate tunneling leakage, and improved device reliability.

STUDY ON NON LINEAR VIBRATION RESPONSE OF PLATE GATES *

This paper deals with the vertical vibration, the horizontal translatory and flexural vibrations of plate gate with a flat bottom under the action of unstable submerged underflow. Based on a non linear resonant oscillator model by which the coupled excitation mechanism between the unstable vortices and gate motion can be simulated, the differential equations for the three types of gate vibrations are established. The parameters in the equations are determined by model experiments. Then, the steady state non linear responses of the three types of gate vibrations are calculated. The calculation results are in good agreement with the experimental data of gate vibrations with different reduced velocity and gate parameters by previous researchers.

Bipolar Quantum Logic Gates and Quantum Cellular Combinatorics—A Logical Extension to Quantum Entanglement

Based on bipolar dynamic logic (BDL) and bipolar quantum linear algebra (BQLA) this work introduces bipolar quantum logic gates and quantum cellular combinatorics with a logical interpretation to quantum entanglement. It is shown that: 1) BDL leads to logically definable causality and generic particle-antiparticle bipolar quantum entanglement;2) BQLA makes composite atom-atom bipolar quantum entanglement reachable. Certain logical equivalence is identified between the new interpretation and established ones. A logical reversibility theorem is presented for ubiquitous quantum computing. Physical reversibility is briefly discussed. It is shown that a bipolar matrix can be either a modular generalization of a quantum logic gate matrix or a cellular connectivity matrix. Based on this observation, a scalable graph theory of quantum cellular combinatorics is proposed. It is contended that this work constitutes an equilibrium-based logical extension to Bohr’s particle-wave complementarity principle, Bohm’s wave function and Bell’s theorem. In the meantime, it is suggested that the result may also serve as a resolution, rather than a falsification, to the EPR paradox and, therefore, a equilibrium-based logical unification of local realism and quantum non-locality.

JE BookⅡ Unit 23 Lesson 90 Bill Gates教学设计

一、教材分析 本课为JE BookⅡ中Unit 23（A famous person）的第2课时，是在第1课时的基础上介绍Bill Gates的成长过程及奋斗经历，文中有较乡单词和疑难长句，是能够培养学生猜测、分析、判断能力的阅读课文。

Construction of DNA-based logic gates on nanostructured microelectrodes

Electrochemical logical operations utilizing biological molecules(protein or DNA), which can be used in disease diagnostics and bio-computing, have attracted great research interest. However, the existing logic operations, being realized on macroscopic electrode, are not suitable for implantable logic devices. Here, we demonstrate DNA-based logic gates with electrochemical signal as output combined with gold flower microelectrodes. The designed logic gates are of fast response, enzyme-free, and micrometer scale. They perform well in either pure solution or complex matrices, such as fetal bovine serum,suggesting great potential for in vivo applications.