Objective To investigate gender differences in the risk factors and awareness,treatment,and control of hypertension.Methods The subjects were selected among local residents aged≥18 years old,by multi-stage stratified...Objective To investigate gender differences in the risk factors and awareness,treatment,and control of hypertension.Methods The subjects were selected among local residents aged≥18 years old,by multi-stage stratified-random sampling method.All participants accepted physical examinations including blood tests for lipids,展开更多
<span style="font-family:Verdana;">Gender difference in chronic hepatitis C (CHC) infection is not previously well studied. We aimed to analyze the effect of gender difference on the risk factors of CH...<span style="font-family:Verdana;">Gender difference in chronic hepatitis C (CHC) infection is not previously well studied. We aimed to analyze the effect of gender difference on the risk factors of CHC, disease progression, and outcome after oral direct acting antiviral (DAA) therapy. The study</span><span style="font-family:Verdana;"> was</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> conducted at Tropical Medicine and Gastroenterology Department, Sohag University, Egypt, in the period between 2018 and 2020. 775 patients were evaluated for hepatitis C virus (HCV) risk factors. Laboratory investigations, abdominal ultrasound and liver Shear </span><span style="font-family:Verdana;">wave elastography (SWE) were done. The patients were given antiviral therap</span><span style="font-family:Verdana;">y and followed up to assess the response and side effects of DAA therapy. 434</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(56%) of study patients were males and 341</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">(44%) were females. Catching infection from blood transfusion and intravenous (IV) injection of </span><span style="font-family:Verdana;">tarter emetic w</span></span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> significantly higher in males, while catching infection from surgical operation was significantly higher in females. Hepatic fibrosis was significantly more extensive in males. Side effects were reported more in females. Sustained virological response (SVR)</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">12 was reported in 98.6%. Females had a slightly better SVR12 than males (99.4% versus 97.9%). In conclusion males were different from females in exposure to HCV risk factors. After introduction of blood screening and stoppage of </span><span style="font-family:Verdana;">parenteral anti-bilharzial therapy the risk of HCV infection could be greatly prevented in males, while the exposure of females to obstetric procedure is increasing nowadays which hide</span></span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> a risk of ongoing infection in females. So, HCV surveillance programs in females retain </span><span style="font-family:Verdana;">their </span><span style="font-family:Verdana;">importance in early detection and management of CHC. Although hepatic fibrosis</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">progression was more in males, females were more liable to adverse events of DAA therapy. So, researchers should consider the gender of their patients in drug design and administration.</span>展开更多
The study of specific differences between women and men is arousing huge interests in various fields of medicine, including dermatology. The available data on gender medicine applied to common skin diseases are unfort...The study of specific differences between women and men is arousing huge interests in various fields of medicine, including dermatology. The available data on gender medicine applied to common skin diseases are unfortunately still scanty. Psoriasis is a chronic immunemediated skin disease which affects 1%-3% of most populations worldwide and can involve also the joints and entheses. The pathogenesis of the disease is very complex, resulting from the interaction between genetic predisposition and several environmental triggers. The pathogenic role of sex hormones has also been hypothesized. The analysis of gender-specific differences in psoriasis seems to suggest some interesting findings, such as an earlier age of disease onset in females, a higher probability of severe disease in men, or different tendencies in care utilization, adherence to treatment, development of psychological distress, and coping strategies. Moreover, sex-related differences have been recently described in some epidemiological and clinical features among patients with psoriatic arthritis. The objective of this article is to review briefly the available evidence regarding gender differences in various aspects of psoriasis, such as epidemiology, genetics, risk factors, associated conditions, quality of life, clinical and therapeutic aspects.展开更多
文摘Objective To investigate gender differences in the risk factors and awareness,treatment,and control of hypertension.Methods The subjects were selected among local residents aged≥18 years old,by multi-stage stratified-random sampling method.All participants accepted physical examinations including blood tests for lipids,
文摘<span style="font-family:Verdana;">Gender difference in chronic hepatitis C (CHC) infection is not previously well studied. We aimed to analyze the effect of gender difference on the risk factors of CHC, disease progression, and outcome after oral direct acting antiviral (DAA) therapy. The study</span><span style="font-family:Verdana;"> was</span><span style="font-family:;" "=""><span style="font-family:Verdana;"> conducted at Tropical Medicine and Gastroenterology Department, Sohag University, Egypt, in the period between 2018 and 2020. 775 patients were evaluated for hepatitis C virus (HCV) risk factors. Laboratory investigations, abdominal ultrasound and liver Shear </span><span style="font-family:Verdana;">wave elastography (SWE) were done. The patients were given antiviral therap</span><span style="font-family:Verdana;">y and followed up to assess the response and side effects of DAA therapy. 434</span></span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">(56%) of study patients were males and 341</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">(44%) were females. Catching infection from blood transfusion and intravenous (IV) injection of </span><span style="font-family:Verdana;">tarter emetic w</span></span><span style="font-family:Verdana;">as</span><span style="font-family:Verdana;"> significantly higher in males, while catching infection from surgical operation was significantly higher in females. Hepatic fibrosis was significantly more extensive in males. Side effects were reported more in females. Sustained virological response (SVR)</span><span style="font-family:;" "=""> </span><span style="font-family:;" "=""><span style="font-family:Verdana;">12 was reported in 98.6%. Females had a slightly better SVR12 than males (99.4% versus 97.9%). In conclusion males were different from females in exposure to HCV risk factors. After introduction of blood screening and stoppage of </span><span style="font-family:Verdana;">parenteral anti-bilharzial therapy the risk of HCV infection could be greatly prevented in males, while the exposure of females to obstetric procedure is increasing nowadays which hide</span></span><span style="font-family:Verdana;">s</span><span style="font-family:Verdana;"> a risk of ongoing infection in females. So, HCV surveillance programs in females retain </span><span style="font-family:Verdana;">their </span><span style="font-family:Verdana;">importance in early detection and management of CHC. Although hepatic fibrosis</span><span style="font-family:;" "=""> </span><span style="font-family:Verdana;">progression was more in males, females were more liable to adverse events of DAA therapy. So, researchers should consider the gender of their patients in drug design and administration.</span>
文摘The study of specific differences between women and men is arousing huge interests in various fields of medicine, including dermatology. The available data on gender medicine applied to common skin diseases are unfortunately still scanty. Psoriasis is a chronic immunemediated skin disease which affects 1%-3% of most populations worldwide and can involve also the joints and entheses. The pathogenesis of the disease is very complex, resulting from the interaction between genetic predisposition and several environmental triggers. The pathogenic role of sex hormones has also been hypothesized. The analysis of gender-specific differences in psoriasis seems to suggest some interesting findings, such as an earlier age of disease onset in females, a higher probability of severe disease in men, or different tendencies in care utilization, adherence to treatment, development of psychological distress, and coping strategies. Moreover, sex-related differences have been recently described in some epidemiological and clinical features among patients with psoriatic arthritis. The objective of this article is to review briefly the available evidence regarding gender differences in various aspects of psoriasis, such as epidemiology, genetics, risk factors, associated conditions, quality of life, clinical and therapeutic aspects.
