Epidemiological Characteristics and Genotypes of Human Papillomavirus Infection in Mianyang

Objective:To investigate the epidemiological characteristics and genotypes of human papillomavirus(HPV)infection in Mianyang.Methods:The cervical samples of 27,040 patients,who visited the Department of Gynecology of The Third Hospital of Mianyang from January 2018 to January 2020,were collected.Results:The HPV-positive infection rate was 21.40%(5,787/27,040);the single HPV infection rate was 72.04%(4,169/5,787);the double HPV infection rate was 19.73%(1,142/5,787);the triple and above HPV infection rate was 8.22%(476/5,787);the top five high-risk HPV subtypes with the highest infection rates were HPV52,16,58,53,and 51,while the top five low-risk HPV subtypes with the highest infection rates were HPV81,42,43,6,and 11;there were significant differences in the HPV-positive infection rate,high-risk infection rate,low-risk infection rate,and multiple infection rate among different age groups(P<0.05).Conclusion:The HPV infection rate in Mianyang was 21.4%,in which the majority of the cases were single infection;the high-risk HPV subtypes were HPV52,16,58,53,and 51;the HPV-positive infection rate,high-risk infection rate,low-risk infection rate,and multiple infection rate were high in the middle but low at both ends in the context of age distribution;the top three age groups with the highest infection rates were 45-49,40-44,and 30-34.