This paper develops an SIBR cholera transmission model with general incidence rate. Necessary and sufficient conditions for local and global asymptotic stability of the equilibria are established by Routh Hurwitz crit...This paper develops an SIBR cholera transmission model with general incidence rate. Necessary and sufficient conditions for local and global asymptotic stability of the equilibria are established by Routh Hurwitz criterium, Lyapunov function, and the second additive composite matrix theorem. What is more, exploiting the DED is cover simulation tool, the parameter values of the model are estimated with the 1998-2021 cholera case data in China. Finally, we perform sensitivity analysis for the basic reproduction number to seek for effective interventions for cholera control. .展开更多
In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By u...In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By using strict monotonicity of the incidence function and constructing a Lyapunov functional, we obtain sufficient conditions under which the endemic equilibrium is globally asymptotically stable. When the nonlinear inci- dence rate is a saturated incidence rate, our result provides a new global stability condition for a small rate of immunity loss.展开更多
A SIQS epidemic model with saturated incidence rate is studied. Two equilibrium points exist for the system, disease-free and endemic equilibrium. The stability of the disease-free equilibrium and endemic equilibrium ...A SIQS epidemic model with saturated incidence rate is studied. Two equilibrium points exist for the system, disease-free and endemic equilibrium. The stability of the disease-free equilibrium and endemic equilibrium exists when the basic reproduction number R0, is less or greater than unity respectively. The global stability of the disease-free and endemic equilibrium is proved using Lyapunov functions and Poincare-Bendixson theorem plus Dulac’s criterion respectively.展开更多
The article investigates a SIQR epidemic model with specific nonlinear incidence rate and stochastic model based on the former, respectively. For deterministic model, we study the existence and stability of the equili...The article investigates a SIQR epidemic model with specific nonlinear incidence rate and stochastic model based on the former, respectively. For deterministic model, we study the existence and stability of the equilibrium points by controlling threshold parameter R0 which determines whether the disease disappears or prevails. Then by using Routh-Hurwitz criteria and constructing suitable Lyapunov function, we get that the disease-free equilibrium is globally asymptotically stable if R0 or unstable if R0>1. In addition, the endemic equilibrium point is globally asymptotically stable in certain region when R0>1. For the corresponding stochastic model, the existence and uniqueness of the global positive solution are discussed and some sufficient conditions for the extinction of the disease and the persistence in the mean are established by defining its related stochastic threshold R0s. Moreover, our analytical results show that the introduction of random fluctuations can suppress disease outbreak. And numerical simulations are used to confirm the theoretical results.展开更多
In this paper, we treat the spread of COVID-19 using a delayed stochastic SVIRS (Susceptible, Infected, Recovered, Susceptible) epidemic model with a general incidence rate and differential susceptibility. We start wi...In this paper, we treat the spread of COVID-19 using a delayed stochastic SVIRS (Susceptible, Infected, Recovered, Susceptible) epidemic model with a general incidence rate and differential susceptibility. We start with a deterministic model, then add random perturbations on the contact rate using white noise to obtain a stochastic model. We first show that the delayed stochastic differential equation that describes the model has a unique global positive solution for any positive initial value. Under the condition R<sub>0</sub> ≤ 1, we prove the almost sure asymptotic stability of the disease-free equilibrium of the model.展开更多
In this paper, we study a kind of the delayed SEIQR infectious disease model with the quarantine and latent, and get the threshold value which determines the global dynamics and the outcome of the disease. The model h...In this paper, we study a kind of the delayed SEIQR infectious disease model with the quarantine and latent, and get the threshold value which determines the global dynamics and the outcome of the disease. The model has a disease-free equilibrium which is unstable when the basic reproduction number is greater than unity. At the same time, it has a unique endemic equilibrium when the basic reproduction number is greater than unity. According to the mathematical dynamics analysis, we show that disease-free equilibrium and endemic equilibrium are locally asymptotically stable by using Hurwitz criterion and they are globally asymptotically stable by using suitable Lyapunov functions for any Besides, the SEIQR model with nonlinear incidence rate is studied, and the that the basic reproduction number is a unity can be found out. Finally, numerical simulations are performed to illustrate and verify the conclusions that will be useful for us to control the spread of infectious diseases. Meanwhile, the will effect changing trends of in system (1), which is obvious in simulations. Here, we take as an example to explain that.展开更多
文摘This paper develops an SIBR cholera transmission model with general incidence rate. Necessary and sufficient conditions for local and global asymptotic stability of the equilibria are established by Routh Hurwitz criterium, Lyapunov function, and the second additive composite matrix theorem. What is more, exploiting the DED is cover simulation tool, the parameter values of the model are estimated with the 1998-2021 cholera case data in China. Finally, we perform sensitivity analysis for the basic reproduction number to seek for effective interventions for cholera control. .
基金supported in part by JSPS Fellows,No.237213 of Japan Society for the Promotion of Science to the first authorthe Grant MTM2010-18318 of the MICINN,Spanish Ministry of Science and Innovation to the second authorScientific Research (c),No.21540230 of Japan Society for the Promotion of Science to the third author
文摘In this article, we establish the global asymptotic stability of a disease-free equilibrium and an endemic equilibrium of an SIRS epidemic model with a class of nonlin- ear incidence rates and distributed delays. By using strict monotonicity of the incidence function and constructing a Lyapunov functional, we obtain sufficient conditions under which the endemic equilibrium is globally asymptotically stable. When the nonlinear inci- dence rate is a saturated incidence rate, our result provides a new global stability condition for a small rate of immunity loss.
文摘A SIQS epidemic model with saturated incidence rate is studied. Two equilibrium points exist for the system, disease-free and endemic equilibrium. The stability of the disease-free equilibrium and endemic equilibrium exists when the basic reproduction number R0, is less or greater than unity respectively. The global stability of the disease-free and endemic equilibrium is proved using Lyapunov functions and Poincare-Bendixson theorem plus Dulac’s criterion respectively.
文摘The article investigates a SIQR epidemic model with specific nonlinear incidence rate and stochastic model based on the former, respectively. For deterministic model, we study the existence and stability of the equilibrium points by controlling threshold parameter R0 which determines whether the disease disappears or prevails. Then by using Routh-Hurwitz criteria and constructing suitable Lyapunov function, we get that the disease-free equilibrium is globally asymptotically stable if R0 or unstable if R0>1. In addition, the endemic equilibrium point is globally asymptotically stable in certain region when R0>1. For the corresponding stochastic model, the existence and uniqueness of the global positive solution are discussed and some sufficient conditions for the extinction of the disease and the persistence in the mean are established by defining its related stochastic threshold R0s. Moreover, our analytical results show that the introduction of random fluctuations can suppress disease outbreak. And numerical simulations are used to confirm the theoretical results.
文摘In this paper, we treat the spread of COVID-19 using a delayed stochastic SVIRS (Susceptible, Infected, Recovered, Susceptible) epidemic model with a general incidence rate and differential susceptibility. We start with a deterministic model, then add random perturbations on the contact rate using white noise to obtain a stochastic model. We first show that the delayed stochastic differential equation that describes the model has a unique global positive solution for any positive initial value. Under the condition R<sub>0</sub> ≤ 1, we prove the almost sure asymptotic stability of the disease-free equilibrium of the model.
基金The authors would like to thank the anonymous referees and the editor for very helpful suggestions and comments which led to improvements of our orig- inal paper. J. Wang was supported by National Natural Science Foundation of China (Nos. 11401182 and 11471089), Natural Science Foundation of Heilongjiang Province (No. A201415), Science and Technology Innovation Team in Higher Edu- cation Institutions of Heilongjiang Province (No. 2014TD005), Project funded by China Postdoctoral Science Foundation (No. 2014M552295) and Project funded by Chongqing Postdoctoral Foundation (No. Xm2014024). X. Wang is supported by the National Natural Science Foundation of China (No. 11301453), Postdoctoral Science Foundation of China (No. 2014M562366), Postdoctoral Science Foundation of Shaanxi Province (No. 2014010), the Universities Young Teachers Program of Henan Province (No. 2014GGJS-093).
基金National Natural Science Foundation of China(11171284)National Science Foundation of the Education Department of Henan Province(2010B110021,2010GGJS-104)The Youth Science Foundation of Xinyang Normal University(20100070)
文摘In this paper, we study a kind of the delayed SEIQR infectious disease model with the quarantine and latent, and get the threshold value which determines the global dynamics and the outcome of the disease. The model has a disease-free equilibrium which is unstable when the basic reproduction number is greater than unity. At the same time, it has a unique endemic equilibrium when the basic reproduction number is greater than unity. According to the mathematical dynamics analysis, we show that disease-free equilibrium and endemic equilibrium are locally asymptotically stable by using Hurwitz criterion and they are globally asymptotically stable by using suitable Lyapunov functions for any Besides, the SEIQR model with nonlinear incidence rate is studied, and the that the basic reproduction number is a unity can be found out. Finally, numerical simulations are performed to illustrate and verify the conclusions that will be useful for us to control the spread of infectious diseases. Meanwhile, the will effect changing trends of in system (1), which is obvious in simulations. Here, we take as an example to explain that.