BACKGROUND Little is known about health status and quality of life(QoL)after implantable cardioverter-defibrillator(ICD)generator exchange(GE).METHODS We prospectively followed patients undergoing first-time ICD GE.Se...BACKGROUND Little is known about health status and quality of life(QoL)after implantable cardioverter-defibrillator(ICD)generator exchange(GE).METHODS We prospectively followed patients undergoing first-time ICD GE.Serial assessments of health status were performed by administering the 36-Item Short Form Survey(SF-36).RESULTS Mean age was 67.5±14.3 years,left ventricle ejection fraction(LVEF)was 36.5%±15.0%and over 40%of the cohort had improved LVEF to>35%at the time of GE.SF-36 scores were significantly worse in physical/general health domains compared to domains of emotional/social well-being(P<0.001 for each comparison).Physical health scores were significantly worse among those with medical comorbidities including diabetes,chronic obstructive pulmonary disease and atrial fibrillation.Mean follow-up was 1.6±0.5 years after GE.Overall SF-36 scores remained stable across all domains during follow-up.Survival at 3 years post-GE was estimated at 80%.Five patients died during follow-up and most deaths were adjudicated as non-arrhythmic in origin.Four patients experienced appropriate ICD shocks after GE,three of whom had LVEF which remains impaired LVEF(i.e.,<35%)at the time of GE.CONCLUSION Patients undergoing ICD GE have significantly worse physical health compared to emotional/social well-being,which is associated with the presence of medical comorbidities.In terms of clinical outcomes,the incidence of appropriate shocks after GE among those with improvement in LVEF is very low,and most deaths post-procedure appear to be non-arrhythmic in origin.These data represent an attempt to more fully characterize the spectrum of QoL and clinical outcomes after GE.展开更多
The wind energy generation,utilization and its grid penetration in electrical grid are increasing world-wide.The wind generated power is always fluctuating due to its time varying nature and causing stability problem....The wind energy generation,utilization and its grid penetration in electrical grid are increasing world-wide.The wind generated power is always fluctuating due to its time varying nature and causing stability problem.This weak interconnection of wind generating source in the electrical network affects the power quality and reliability.The localized energy storages shall compensate the fluctuating power and support to strengthen the wind generator in the power system.In this paper,it is proposed to control the voltage source inverter （VSI） in current control mode with energy storage,that is,batteries across the dc bus.The generated wind power can be extracted under varying wind speed and stored in the batteries.This energy storage maintains the stiff voltage across the dc bus of the voltage source inverter.The proposed scheme enhances the stability and reliability of the power system and maintains unity power factor.It can also be operated in stand-alone mode in the power system.The power exchange across the wind generation and the load under dynamic situation is feasible while maintaining the power quality norms at the common point of coupling.It strengthens the weak grid in the power system.This control strategy is evaluated on the test system under dynamic condition by using simulation.The results are verified by comparing the performance of controllers.展开更多
基金supported by a Pilot Translational&Clinical Studies Program grant from the National Center for Advancing Translational Studies of the National Institutes of Health(UL1TR002378)a FAME grant from the Emory University Department of Medicine。
文摘BACKGROUND Little is known about health status and quality of life(QoL)after implantable cardioverter-defibrillator(ICD)generator exchange(GE).METHODS We prospectively followed patients undergoing first-time ICD GE.Serial assessments of health status were performed by administering the 36-Item Short Form Survey(SF-36).RESULTS Mean age was 67.5±14.3 years,left ventricle ejection fraction(LVEF)was 36.5%±15.0%and over 40%of the cohort had improved LVEF to>35%at the time of GE.SF-36 scores were significantly worse in physical/general health domains compared to domains of emotional/social well-being(P<0.001 for each comparison).Physical health scores were significantly worse among those with medical comorbidities including diabetes,chronic obstructive pulmonary disease and atrial fibrillation.Mean follow-up was 1.6±0.5 years after GE.Overall SF-36 scores remained stable across all domains during follow-up.Survival at 3 years post-GE was estimated at 80%.Five patients died during follow-up and most deaths were adjudicated as non-arrhythmic in origin.Four patients experienced appropriate ICD shocks after GE,three of whom had LVEF which remains impaired LVEF(i.e.,<35%)at the time of GE.CONCLUSION Patients undergoing ICD GE have significantly worse physical health compared to emotional/social well-being,which is associated with the presence of medical comorbidities.In terms of clinical outcomes,the incidence of appropriate shocks after GE among those with improvement in LVEF is very low,and most deaths post-procedure appear to be non-arrhythmic in origin.These data represent an attempt to more fully characterize the spectrum of QoL and clinical outcomes after GE.
文摘The wind energy generation,utilization and its grid penetration in electrical grid are increasing world-wide.The wind generated power is always fluctuating due to its time varying nature and causing stability problem.This weak interconnection of wind generating source in the electrical network affects the power quality and reliability.The localized energy storages shall compensate the fluctuating power and support to strengthen the wind generator in the power system.In this paper,it is proposed to control the voltage source inverter （VSI） in current control mode with energy storage,that is,batteries across the dc bus.The generated wind power can be extracted under varying wind speed and stored in the batteries.This energy storage maintains the stiff voltage across the dc bus of the voltage source inverter.The proposed scheme enhances the stability and reliability of the power system and maintains unity power factor.It can also be operated in stand-alone mode in the power system.The power exchange across the wind generation and the load under dynamic situation is feasible while maintaining the power quality norms at the common point of coupling.It strengthens the weak grid in the power system.This control strategy is evaluated on the test system under dynamic condition by using simulation.The results are verified by comparing the performance of controllers.
