A relatively high aerodynamic drag is an important factor that hinders the further acceleration of high-speed trains.Using the shear stress transport(SST)k-ωturbulence model,the effect of various vortex generator typ...A relatively high aerodynamic drag is an important factor that hinders the further acceleration of high-speed trains.Using the shear stress transport(SST)k-ωturbulence model,the effect of various vortex generator types on the aerodynamic characteristics of an ICE2(Inter-city Electricity)train has been investigated.The results indi-cate that the vortex generators with wider triangle,trapezoid,and micro-ramp arranged on the surface of the tail car can significantly change the distribution of surface pressure and affect the vorticity intensity in the wake.This alteration effectively reduces the resistance of the tail car.Meanwhile,the micro-ramp vortex generator with its convergent structure at the rear exhibits enhancedflow-guiding capabilities,resulting in a 15.4%reduction in the drag of the tail car.展开更多
In the quantum Monte Carlo(QMC)method,the pseudo-random number generator(PRNG)plays a crucial role in determining the computation time.However,the hidden structure of the PRNG may lead to serious issues such as the br...In the quantum Monte Carlo(QMC)method,the pseudo-random number generator(PRNG)plays a crucial role in determining the computation time.However,the hidden structure of the PRNG may lead to serious issues such as the breakdown of the Markov process.Here,we systematically analyze the performance of different PRNGs on the widely used QMC method known as the stochastic series expansion(SSE)algorithm.To quantitatively compare them,we introduce a quantity called QMC efficiency that can effectively reflect the efficiency of the algorithms.After testing several representative observables of the Heisenberg model in one and two dimensions,we recommend the linear congruential generator as the best choice of PRNG.Our work not only helps improve the performance of the SSE method but also sheds light on the other Markov-chain-based numerical algorithms.展开更多
Thermoelectric generators(TEGs)are considered promising devices for waste heat recovery from various systems.The Seebeck effect can be utilized to generate power using the residual heat emitted by the filter dryer rec...Thermoelectric generators(TEGs)are considered promising devices for waste heat recovery from various systems.The Seebeck effect can be utilized to generate power using the residual heat emitted by the filter dryer receiver(FDR)of an air conditioning(A/C)system,which would otherwise go to waste.The study aims to build a set of thermoelectric generators(TEG)to collect the waste heat of the FDR and generate low-power electricity.A novel electrical circuit with two transformers is designed and fabricated to produce a more stable voltage for operation and charging.The thermoelectric generator(TEGs)was installed on the FDR of the A/C unit.The test showed that climate conditions have a significant impact on the output power generated from the system.The results showed that the peak voltage recorded in the current study is 5.2 V per day(wet,cold,and wind weather)with an output power of 0.2 W.These values are acceptable for powering the load and charging a single battery with 3.5 V as the voltage increases battery 0.1 V/20 min charge.A case study of operating the emergency signs in a building was considered.The current heat recovery system is deemed to be easily installed and can be connected to a network of TEGs to produce more power.展开更多
The utilization of vortex generators to increase heat transfer from cylinders installed inside a duct is investigated.In particular,a channel containing eight cylinders with volumetric heat sources is considered for d...The utilization of vortex generators to increase heat transfer from cylinders installed inside a duct is investigated.In particular,a channel containing eight cylinders with volumetric heat sources is considered for different values of the Reynolds number.The effective possibility to use vortex generators with different sizes to increase heat transfer and,consequently,reduce the surface temperature of the cylinders is examined.Also,the amount of pressure drop inside the channel due to the presence of vortex generators is considered and compared with the cases without vortex generators.The results show that although the addition of generators increases the pressure drop,it strongly contributes to increase the heat transfer coefficient inside the duct(up to 80–90%).展开更多
Our community currently deals with issues such as rising electricity costs,pollution,and global warming.Scientists work to improve energy harvesting-based power generators in order to reduce their impacts.The Seebeck ...Our community currently deals with issues such as rising electricity costs,pollution,and global warming.Scientists work to improve energy harvesting-based power generators in order to reduce their impacts.The Seebeck effect has been used to illustrate the capacity of thermoelectric generators(TEGs)to directly convert thermal energy to electrical energy.They are also ecologically beneficial since they do not include chemical products,function quietly because they lack mechanical structures and/or moving components,and may be built using different fabrication technologies such as three-dimentional(3D)printing,silicon technology,and screen printing,etc.TEGs are also position-independent and have a long operational lifetime.TEGs can be integrated into bulk and flexible devices.This review gives further investigation of TEGs,beginning with a full discussion of their operating principle,kinds,materials utilized,figure of merit,and improvement approaches,which include various thermoelectric material arrangements and utilised technologies.This paper also discusses the use of TEGs in a variety of disciplines such as automobile and biomedical.展开更多
DNA methylation is a critical epigenetic regulator in the occurrence and development of diseases and is closely related to various functional responses in relation to spinal cord injury.To investigate the role of DNA ...DNA methylation is a critical epigenetic regulator in the occurrence and development of diseases and is closely related to various functional responses in relation to spinal cord injury.To investigate the role of DNA methylation in spinal cord injury,we constructed a library with reduced-representation bisulfite sequencing data obtained at various time points(day 0-42)after spinal cord injury in mice.Global DNA methylation levels,specifically non-CpG(CHG and CHH)methylation levels,decreased modestly following spinal cord injury.Stages post-spinal cord injury were classified as early(day 0-3),intermediate(day7-14),and late(day 28-42)based on similarity and hie rarchical cluste ring of global DNA methylation patterns.The non-CpG methylation level,which included CHG and CHH methylation levels,was markedly reduced despite accounting for a minor proportion of total methylation abundance.At multiple genomic sites,including the 5’untranslated regions,promoter,exon,intron,and 3’untranslated regions,the non-CpG methylation level was markedly decreased following spinal cord injury,whereas the CpG methylation level remained unchanged at these locations.Approximately one-half of the differentially methylated regions were located in intergenic areas;the other differentially methylated regions in both CpG and non-CpG regions were cluste red in intron regions,where the DNA methylation level was highest.The function of genes associated with differentially methylated regions in promoter regions was also investigated.From Gene Ontology analysis results,DNA methylation was implicated in a number of essential functional responses to spinal cord injury,including neuronal synaptic connection creation and axon regeneration.Notably,neither CpG methylation nor non-CpG methylation was implicated in the functional response of glial or inflammatory cells.In summary,our work elucidated the dynamic pattern of DNA methylation in the spinal co rd following injury and identified reduced nonCpG methylation as an epigenetic target after spinal cord injury in mice.展开更多
基金supported by the National Natural Science Foundation of China(12372049)Sichuan Science and Technology Program(2023JDRC0062)+1 种基金Science and Technology Program of China National Accreditation Service for Conformity Assessment(2022CNAS15)the Independent Project of State Key Laboratory of Rail Transit Vehicle System(2023TPL-T06).
文摘A relatively high aerodynamic drag is an important factor that hinders the further acceleration of high-speed trains.Using the shear stress transport(SST)k-ωturbulence model,the effect of various vortex generator types on the aerodynamic characteristics of an ICE2(Inter-city Electricity)train has been investigated.The results indi-cate that the vortex generators with wider triangle,trapezoid,and micro-ramp arranged on the surface of the tail car can significantly change the distribution of surface pressure and affect the vorticity intensity in the wake.This alteration effectively reduces the resistance of the tail car.Meanwhile,the micro-ramp vortex generator with its convergent structure at the rear exhibits enhancedflow-guiding capabilities,resulting in a 15.4%reduction in the drag of the tail car.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.12274046,11874094,and 12147102)Chongqing Natural Science Foundation(Grant No.CSTB2022NSCQ-JQX0018)Fundamental Research Funds for the Central Universities(Grant No.2021CDJZYJH-003).
文摘In the quantum Monte Carlo(QMC)method,the pseudo-random number generator(PRNG)plays a crucial role in determining the computation time.However,the hidden structure of the PRNG may lead to serious issues such as the breakdown of the Markov process.Here,we systematically analyze the performance of different PRNGs on the widely used QMC method known as the stochastic series expansion(SSE)algorithm.To quantitatively compare them,we introduce a quantity called QMC efficiency that can effectively reflect the efficiency of the algorithms.After testing several representative observables of the Heisenberg model in one and two dimensions,we recommend the linear congruential generator as the best choice of PRNG.Our work not only helps improve the performance of the SSE method but also sheds light on the other Markov-chain-based numerical algorithms.
文摘Thermoelectric generators(TEGs)are considered promising devices for waste heat recovery from various systems.The Seebeck effect can be utilized to generate power using the residual heat emitted by the filter dryer receiver(FDR)of an air conditioning(A/C)system,which would otherwise go to waste.The study aims to build a set of thermoelectric generators(TEG)to collect the waste heat of the FDR and generate low-power electricity.A novel electrical circuit with two transformers is designed and fabricated to produce a more stable voltage for operation and charging.The thermoelectric generator(TEGs)was installed on the FDR of the A/C unit.The test showed that climate conditions have a significant impact on the output power generated from the system.The results showed that the peak voltage recorded in the current study is 5.2 V per day(wet,cold,and wind weather)with an output power of 0.2 W.These values are acceptable for powering the load and charging a single battery with 3.5 V as the voltage increases battery 0.1 V/20 min charge.A case study of operating the emergency signs in a building was considered.The current heat recovery system is deemed to be easily installed and can be connected to a network of TEGs to produce more power.
文摘The utilization of vortex generators to increase heat transfer from cylinders installed inside a duct is investigated.In particular,a channel containing eight cylinders with volumetric heat sources is considered for different values of the Reynolds number.The effective possibility to use vortex generators with different sizes to increase heat transfer and,consequently,reduce the surface temperature of the cylinders is examined.Also,the amount of pressure drop inside the channel due to the presence of vortex generators is considered and compared with the cases without vortex generators.The results show that although the addition of generators increases the pressure drop,it strongly contributes to increase the heat transfer coefficient inside the duct(up to 80–90%).
文摘Our community currently deals with issues such as rising electricity costs,pollution,and global warming.Scientists work to improve energy harvesting-based power generators in order to reduce their impacts.The Seebeck effect has been used to illustrate the capacity of thermoelectric generators(TEGs)to directly convert thermal energy to electrical energy.They are also ecologically beneficial since they do not include chemical products,function quietly because they lack mechanical structures and/or moving components,and may be built using different fabrication technologies such as three-dimentional(3D)printing,silicon technology,and screen printing,etc.TEGs are also position-independent and have a long operational lifetime.TEGs can be integrated into bulk and flexible devices.This review gives further investigation of TEGs,beginning with a full discussion of their operating principle,kinds,materials utilized,figure of merit,and improvement approaches,which include various thermoelectric material arrangements and utilised technologies.This paper also discusses the use of TEGs in a variety of disciplines such as automobile and biomedical.
基金National Key Research and Development Program of China,No.2016YFA0100800(to LC)International(Regional)Cooperation and Communication Program of the National Natural Science Foundation of China,No.81820108013(to LC)+3 种基金State Key Program of the National Natural Science Foundation of China,No.81330030(to LC)National Natural Science Foundation of China,Nos.82071370(to ZW),81301042(to LC)Shanghai Pujiang Program,No.19PJ1409200(to ZW)Shanghai Sailing Program,No.21YF1442400(to CL)。
文摘DNA methylation is a critical epigenetic regulator in the occurrence and development of diseases and is closely related to various functional responses in relation to spinal cord injury.To investigate the role of DNA methylation in spinal cord injury,we constructed a library with reduced-representation bisulfite sequencing data obtained at various time points(day 0-42)after spinal cord injury in mice.Global DNA methylation levels,specifically non-CpG(CHG and CHH)methylation levels,decreased modestly following spinal cord injury.Stages post-spinal cord injury were classified as early(day 0-3),intermediate(day7-14),and late(day 28-42)based on similarity and hie rarchical cluste ring of global DNA methylation patterns.The non-CpG methylation level,which included CHG and CHH methylation levels,was markedly reduced despite accounting for a minor proportion of total methylation abundance.At multiple genomic sites,including the 5’untranslated regions,promoter,exon,intron,and 3’untranslated regions,the non-CpG methylation level was markedly decreased following spinal cord injury,whereas the CpG methylation level remained unchanged at these locations.Approximately one-half of the differentially methylated regions were located in intergenic areas;the other differentially methylated regions in both CpG and non-CpG regions were cluste red in intron regions,where the DNA methylation level was highest.The function of genes associated with differentially methylated regions in promoter regions was also investigated.From Gene Ontology analysis results,DNA methylation was implicated in a number of essential functional responses to spinal cord injury,including neuronal synaptic connection creation and axon regeneration.Notably,neither CpG methylation nor non-CpG methylation was implicated in the functional response of glial or inflammatory cells.In summary,our work elucidated the dynamic pattern of DNA methylation in the spinal co rd following injury and identified reduced nonCpG methylation as an epigenetic target after spinal cord injury in mice.
