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Genome Mapping to Enhance Efficient Marker-Assisted Selection and Breeding of the Oil Palm (<i>Elaeis guineensis</i>Jacq.)
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作者 Essubalew Getachew Seyum Ngalle Hermine Bille +2 位作者 Wosene Gebreselassie Abtew Godswill Ntsomboh-Ntsefong Joseph Martin Bell 《Advances in Bioscience and Biotechnology》 2021年第12期407-425,共19页
The oil palm (<i>Elaeis</i> <i>guineensis</i> Jacq.) is one of the major cultivated crops among the economically important palm species. It is cultivated mainly for its edible oil. For a perenn... The oil palm (<i>Elaeis</i> <i>guineensis</i> Jacq.) is one of the major cultivated crops among the economically important palm species. It is cultivated mainly for its edible oil. For a perennial crop like oil palm, the use of Marker Assisted Selection (MAS) techniques helps to reduce the breeding cycle and improve the economic products. Genetic and physical maps are important for sequencing experiments since they show the exact positions of genes and other distinctive features in the chromosomal DNA. This review focuses on the role of genome mapping in oil palm breeding. It assesses the role of genome mapping in oil palm breeding and discusses the major factors affecting such mapping. Generating a high-density map governed by several factors, for instance, marker type, marker density, number of mapped population, and software used are the major issues treated. The general conclusion is that genome mapping is pivotal in the construction of a genetic linkage map. It helps to detect QTL and identify genes that control quantitative traits in oil palm. In perspective, the use of high-density molecular markers with a large number of markers, a large number mapping population, and up-to-date softw<span style="color:;">are </span><span>is necessary</span><span style="color:;"> for oil pal</span>m genome mapping. 展开更多
关键词 genome Mapping Crop Improvement Marker Assisted Selection Oil Palm BIOTECHNOLOGY
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Development of Permanent Mapping Populations RILs in Diploid A Genome
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作者 WAGHMARE VIJAY N DONGRE A B GOTMARE Vinita PATIL P G DESHPANDE L A KHADI B M 《棉花学报》 CSCD 北大核心 2008年第S1期99-,共1页
Recombinant inbred lines(RILs) serve as powerful tools for genetic mapping.RILs are obtained by crossing two inbred lines followed by repeated selfing or sib-mating to create a set of new
关键词 QTLS LENGTH Development of Permanent Mapping Populations RILs in Diploid A genome
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The Human Genome Map
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作者 Tang Yuankai 《ChinAfrica》 2013年第3期58-58,共1页
ON April 14, 2003, scientists from China, the United States. Japan, Germany, France and Britain announced they had completed sequence mapping of the human genome, marking the end of the Human Genome Project (HGP) st... ON April 14, 2003, scientists from China, the United States. Japan, Germany, France and Britain announced they had completed sequence mapping of the human genome, marking the end of the Human Genome Project (HGP) started in 1990. Yang Huanming, an academician from the Chinese Academy of Sciences (CAS) and Chairman of the Shenzhen branch of the Beijing Genomics Institute (BGI). led the group of Chinese experts that contributed to the project. The Chinese team played an integral part in the research unti August 26, 2001. 展开更多
关键词 The Human genome Map HIV
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CONSTRUCTION OF A CONTIG MAP OF THE RICE GENOME
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作者 National Center for Gene Research, CAS 《Bulletin of the Chinese Academy of Sciences》 1998年第1期29-35,共7页
In August 1992, the State S&T Commission(SSTC) of China announced that China would launch a Rice Genome Program, a counterpart to the US Program of Human Genome, in a bid to decipher the genetic code of rice at th... In August 1992, the State S&T Commission(SSTC) of China announced that China would launch a Rice Genome Program, a counterpart to the US Program of Human Genome, in a bid to decipher the genetic code of rice at the molecular level and then apply the obtained results to the cultivation of improved strains of the crop. 展开更多
关键词 GENE THAN MORE DNA CONSTRUCTION OF A CONTIG MAP OF THE RICE genome
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Detection of an 8p23.1 Inversion Using High-Resolution Optical Genome Mapping
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作者 Chunxiang Zhou Huijun Li +3 位作者 Yiyan Shi Linlin He Honglei Duan Jie Li 《Maternal-Fetal Medicine》 CAS CSCD 2024年第3期173-177,共5页
Objective:To evaluate the performance of optical genomemapping(OGM)in identifying an inversion located in the short armof chromosome 8(8p,8p23.1),flanked by regions of complex segmental duplication(SD),using the GRCh3... Objective:To evaluate the performance of optical genomemapping(OGM)in identifying an inversion located in the short armof chromosome 8(8p,8p23.1),flanked by regions of complex segmental duplication(SD),using the GRCh38 and telomere-to-telomere(T2T)genome references.Methods:We investigated a couple suspected of carrying the 8p23.1 inversion due to a terminal deletion combined with an interstitial duplication of 8p found in their abortus.OGM was performed on both individuals.The data were mapped to the current GRCh38 and the updated T2T genome references,respectively.Results:The 8p23.1 inversion was observed in the female when mapping OGM data to the T2T assembly.In contrast,under the GRCh38 reference,the orientation between the suspected breakpoints within the SD regions could not be distinguished.Additional variants of uncertain significance were also identified in both individuals.Conclusion:Our findings highlight the superiority of the T2T reference in recognizing structural variations involving SD regions.The enhanced SV detection using the T2T reference may contribute to a better understanding of genome instability and human diseases. 展开更多
关键词 genome mapping Telomere-to-Telomere reference Segmental duplication 8p23.1 inversion
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Working Map of Human Genome Complete
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作者 Patricia Reaney 徐曙 《当代外语研究》 2000年第8期16-19,共4页
提示:2000年6月26日无疑是世界生物史上最具重大意义的一天。研究机构经过长达十年的研究,公布了人类基因图计划。世界舆论甚至将人类基因组图的研究计划称为“生物学上的阿波罗登月计划”。将此与当年人类成功登月相提并论。 本文中提... 提示:2000年6月26日无疑是世界生物史上最具重大意义的一天。研究机构经过长达十年的研究,公布了人类基因图计划。世界舆论甚至将人类基因组图的研究计划称为“生物学上的阿波罗登月计划”。将此与当年人类成功登月相提并论。 本文中提及的马里兰州罗克维尔市的塞利拉基因组公司在加入了这项研究计划之后,研究计划有了飞快的发展,甚至可以用“更上一层楼”来形容。 人类此举的主要意义有两个方面: 一是,人类将把自己独一无二的遗传密码存入智慧卡,一旦主人生病,医生将根据病人的基因类型配制药物,再也不是同一种病开出同一种药。 二是,了解了人类的基因组的秘密最终将会促进最新药物,或曰“灵丹妙药”的研制。 对人类基因的改变并非轻而易举之事。如同学会了简单的字母只是开始接受教育一样,也许需要100年的时间,大功才能告成。 美国总统克林顿“抢先”发表高论:解破人类基因密码,将永远改变“人类保健的全貌”。对此,立即有专家作出反应说:这一说法还为时尚早。 展开更多
关键词 人类基因 克维尔 Working Map of Human genome Complete 基因组 MAP
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Confirmation of susceptibility gene loci on chromosome 1 in Northern China Han families with type 2 diabetes
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作者 杜玮南 孙红霞 +12 位作者 熊墨淼 左瑾 方福德 王■ 孙琦 强伯勤 沈岩 姚志建 顾军 黄薇 陈竺 华秀峰 高伟 《Chinese Medical Journal》 SCIE CAS CSCD 2001年第8期93-95,112,共4页
Objective To confirm previous effort to identify type 2 diabetes susceptibility genes in a Northern Chinese population by conducting a new genome scan with both an increased number of type 2 diabetes families and a n... Objective To confirm previous effort to identify type 2 diabetes susceptibility genes in a Northern Chinese population by conducting a new genome scan with both an increased number of type 2 diabetes families and a new set of microsatellite markers within the previously localized regions.Methods A genome scan method was applied. After multiplexed PCR, electrophoreses, genescan and genotyping analysis, we obtained size information for all loci , and then a further study was done by both parametric and non-parametric linkage analysis to investigate the P values and Z values of these loci.Results We surveyed 34 microsatellite markers which distributed within 5 regions along chromosome 1, and a total of 12?000 genotypes were screened. Evidence of linkage with diabetes was identified for 8 of the 34 loci. All P values of the 8 loci were lower than 0.05, and the highest Z value was 2.17. A very interesting finding is that all 5 markers at the p- terminal 1p36.3-1p36.23 region, spanning a long range of 16.9?cM, were identified to have a low P value of less than 0.05, which suggests that this region may contain multiple susceptibility genes. Regions 4 and 5 also confirmed the previous findings, and we narrowed these two regions to a 2.7?cM and 2.5?cM regions, respectively.Conclusions We further confirmed the results gained in the previous genome-wide scan using an increased number of NIDDM families and a new set of microsatellite markers lying within the initially localized regions. The fact that all 5 loci at the p- terminal region displayed a low P value of less than 0.05 suggests that more than 1 susceptibility gene may reside in this region. 展开更多
关键词 type 2 diabetes · microsatellte mark ers · genome screening · susceptibility genes · gene mapping
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On Bioinformatic Resources
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作者 Runsheng Chen 《Genomics, Proteomics & Bioinformatics》 SCIE CAS CSCD 2015年第1期1-3,共3页
A starting point of curating bioinformatic resources for the public is marked by the establishment of the US National Center for Biotechnology Information(NCBI)in 1988[1].One of its many purposes is certainly to ech... A starting point of curating bioinformatic resources for the public is marked by the establishment of the US National Center for Biotechnology Information(NCBI)in 1988[1].One of its many purposes is certainly to echo the initiative of the Human Genome Project(HGP)––when two landmark reports were published at the same time:‘‘Mapping and Sequencing the Human Genome’’by the National Research Council[2]and‘‘Mapping Our Genes––The Genome Project:How Big,How Fast?’’by the US Congress[3]. 展开更多
关键词 genome Mapping Biotechnology Sequencing initiative landmark disciplines genomic sequenced starting
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