A New Method to Predict Erythrocyte Sedimentation Rate with Natural Geographical Factors and Location by Case-based Reasoning: A Case Study of China

Reference values of erythrocyte sedimentation rate(ESR)are the key to interpret ESR blood test in clinic.The common local reference ESR values are more accuracy in blood test that are established with natural geographical factors by using the multiple linear regression(MLR)model and the artificial neural network(ANN).These knowledge-based methods have limitations since the knowledge domains of ESR and natural geographical factors are limited.This paper presents a new cases-depended model to establish reference ESR values with natural geographical factors and location using case-based reasoning(CBR)since knowledge domain of ESR and geographical factors is weak.Overall 224 local normal ESR values of China that calculated from 13623 samples were obtained,and the corresponding natural geographical factors and location that include altitude,sunshine hours,relative humidity,temperature,precipitation,annual temperature range and annual average wind speed were obtained from the National Geomatics Center of China.CBR was used to predict the unseen local reference ESR values with cases.The average absolute deviation(AAD),mean square error(MSE),prediction accuracy(PA),and Pearson correlation coefficient(r)between the observed and estimated data of proposed model is 33.07%,9.02,66.93% and 0.78,which are better than those of ANN and MLR model.The results show that the proposed model provides higher prediction accuracy than those of the artificial neural network and multiple linear regression models.The predicted values are very close to the observed values.Model results show significant agreement of cases data.Consequently,the model is used to predict the unseen local reference ESR with natural geographical factors and location.In spatial,the highest ESR reference areas are distributed in the southern-western district of China that includes Sichuan,Chongqing,Guangxi and Guizhou provinces,and the reference ESR values are greater than 23 mm/60 min.The higher ESR reference values are distributed in the middle part and northern-eastern of China which include Hubei,Henan,Shaanxi,Shanxi,Jilin and Heilongjiang provinces,and the reference ESR values are greater than 18 mm/60min.The lowest ESR reference values are distributed in the northern-western of China that includes Tibet and Xinjiang,and the reference ESR values are lower than 5 mm/60min.

Institute of Geographic Sciences and Natural Resources Research, CAS

Institute of Geographic Sciences and Natural Resources Research (IGSNRR) was established in late 1999 on the basis of the consolidation of two former CAS institutions: the Institute of Geography and the Commission for Integrated Surveys of Natural Resources. With an aim to promote the coordinated development between population, resources, economy and the environment, the IGSNRR strives to serve the nation’s major needs in resource and the

Born of geographical environment, coloring for regional context： Concept and progress of geo-architecture

In today＇s world, where re-examination has been given to cultural globalization, the relationship between architectures and specific regions is one of many specific issues. At this time, the study of architecture from the perspective of geography has significant meaning for treasuring regional characteristics and protecting the essence of ethnic culture. The study of geo-architecture includes two aspects： the influence of geographical environment upon architecture and reflexively, architectural responses to geographical environment. In ＂Geo-Architecture and Landscape in China＇s Geographic and Historic Context Series＂（4 volumes）, published by Springer Nature in 2016, the contents of ＂geo-architecture＂ has been interpreted from various angles as form, function, semantics and symbol. This book is the first to be entitled ＂Geo-Architecture＂, which studies the relationship between geography and architecture from the perspective of geographical environment and historical context in China. The book＇s research reveals the influences of different geographical scales, such as zone（macro）, region（middle） and site（micro） scales, on architecture; it discusses dynamic and systematic thought, including such research elements as ＂Object-Subject-Time＂, and it reflects views on pattern and process of cultural landscape. Research on geo-architecture aims to help construct the security pattern of the cultural landscape for the new requirements of a new era, which is used to optimize spacial structure, stimulate heritage conservation and renewal, respect the geographical environment, pay attention to historical culture and sustain emotional memory.