Two novel ent-kauranoids with new sub-skeleton types, gesneroidins G and H were isolated as white powder from the ether extract of the leaves of Isodon gesneroides through normal phase column chromatography. Their str...Two novel ent-kauranoids with new sub-skeleton types, gesneroidins G and H were isolated as white powder from the ether extract of the leaves of Isodon gesneroides through normal phase column chromatography. Their structures were elucidated as 3b,6a,7b-triacetoxyl-15-hydroxyl-14-oxo-ent-15,16-seco-kaur-11,17-olide and 1a-hydroxyl-3b,6a,7b,11b-tetraacetoxyl-ent-nor-15,17-kaur-8,16-olide on the basis of the spectral evidences including 1D and 2D NMR spectra.展开更多
Three new diterpenoids, gesneroidins DP (1-3), were isolated from Isodon gesneroides. The structure was determined as 3 beta, 7 beta, 11 beta, 15 beta-tetraacetoxy-ent-kaur-16-en-6-one; 15 beta-hydroxy-1 alpha, 3 beta...Three new diterpenoids, gesneroidins DP (1-3), were isolated from Isodon gesneroides. The structure was determined as 3 beta, 7 beta, 11 beta, 15 beta-tetraacetoxy-ent-kaur-16-en-6-one; 15 beta-hydroxy-1 alpha, 3 beta, 6 alpha, 7 beta, 11 beta-pentaacetoxy-ent-kaur-16-ene; 6 alpha,11 beta-dihydroxy-3 beta, 7 beta-diacetoxy-ent-kaur-16-en-15-one based on 1D and 2D NMR techniques (COSY, NOESY, HXTCOR, COLOC).展开更多
文摘Two novel ent-kauranoids with new sub-skeleton types, gesneroidins G and H were isolated as white powder from the ether extract of the leaves of Isodon gesneroides through normal phase column chromatography. Their structures were elucidated as 3b,6a,7b-triacetoxyl-15-hydroxyl-14-oxo-ent-15,16-seco-kaur-11,17-olide and 1a-hydroxyl-3b,6a,7b,11b-tetraacetoxyl-ent-nor-15,17-kaur-8,16-olide on the basis of the spectral evidences including 1D and 2D NMR spectra.
