Establishment of models to predict factors influencing periodontitis in patients with type 2 diabetes mellitus

BACKGROUND Type 2 diabetes mellitus(T2DM)is associated with periodontitis.Currently,there are few studies proposing predictive models for periodontitis in patients with T2DM.AIM To determine the factors influencing periodontitis in patients with T2DM by constructing logistic regression and random forest models.METHODS In this a retrospective study,300 patients with T2DM who were hospitalized at the First People’s Hospital of Wenling from January 2022 to June 2022 were selected for inclusion,and their data were collected from hospital records.We used logistic regression to analyze factors associated with periodontitis in patients with T2DM,and random forest and logistic regression prediction models were established.The prediction efficiency of the models was compared using the area under the receiver operating characteristic curve(AUC).RESULTS Of 300 patients with T2DM,224 had periodontitis,with an incidence of 74.67%.Logistic regression analysis showed that age[odds ratio(OR)=1.047,95%confidence interval(CI):1.017-1.078],teeth brushing frequency(OR=4.303,95%CI:2.154-8.599),education level(OR=0.528,95%CI:0.348-0.800),glycosylated hemoglobin(HbA1c)(OR=2.545,95%CI:1.770-3.661),total cholesterol(TC)(OR=2.872,95%CI:1.725-4.781),and triglyceride(TG)(OR=3.306,95%CI:1.019-10.723)influenced the occurrence of periodontitis(P<0.05).The random forest model showed that the most influential variable was HbA1c followed by age,TC,TG, education level, brushing frequency, and sex. Comparison of the prediction effects of the two models showedthat in the training dataset, the AUC of the random forest model was higher than that of the logistic regressionmodel (AUC = 1.000 vs AUC = 0.851;P < 0.05). In the validation dataset, there was no significant difference in AUCbetween the random forest and logistic regression models (AUC = 0.946 vs AUC = 0.915;P > 0.05).CONCLUSION Both random forest and logistic regression models have good predictive value and can accurately predict the riskof periodontitis in patients with T2DM.

Massive fibrous epulis——a case report of a 10-year-old lesion

The fibrous epulis, a common tumor-like lesion of the gingiva, appears in the interdental papilla as a result of local irritation. Lesions are asymptomatic and have a variable growth rate. A 75-year-old woman was referred for the evaluation of a large painless gingival mass. It had started 10 years back and has been increasing in size the last year. No bone involvement was noted. The tumor was totally removed by excision with surgical scalpel under local anesthesia without teeth extraction. The microscopic findings were suggestive of a fibrous epulis. Differential diagnosis, clinical considerations and factors to prevent recurrence are discussed.

Oral focal mucinosis arising on the gingiva of orthodontic patient

Oral focal mucinosis is an uncommon non-neoplastic lesion of unknown etiology. We presented a unique case of a sessile, well-demarcated gingival nodule adjacent to the right mandibular first molar of a young girl submitted to orthodontic treatment that was diagnosed as oral focal mucinosis. The probably etiopathogenesis of this lesion in orthodontic patient is discussed.

Giant Fibrous Epulis: A Case Report of a Benign Mass of the Oral Cavity

The epulis is a relatively frequent benign oral lesion that originates from the gingival and which has no degenerative potential. A 73-year-old-woman came to our attention for a mass, located in the oral cavity and more precisely in the right inferior maxillary alveolar ridge, that the patient firstly noticed 2 years earlier. Its dimensions increased over time and now were relevant. The mass was mobile, and non-ulcerated e did not evoke pain when palpated. It was characterized by a thin pedicle and its resection, under local anesthesia, allowed a complete removal of the mass itself. The histological examination showed a fibrous and plasmacellular epulis with calcific spots and mixoid aspects. We here report this case for the unique dimensions of this epulis and in order to give a useful example that could help in the differential diagnosis of the lesions located in the oral cavity.

Five Proven Cases Treated with Acupuncture Therapy

Acupuncture theory is of long history,and is broadand profound.The author used traditional acupuncturetheory to guide clinical practice,and reachedsatisfactory therapeutic effects.Now five cases wereintroduced as follows.