Ginkgo flavonoids are one of the most effective medicinal components extracted from leaves of Ginkgo biloba L.According to the physical and chemical properties of ginkgo flavonoids,they can be separated and purified b...Ginkgo flavonoids are one of the most effective medicinal components extracted from leaves of Ginkgo biloba L.According to the physical and chemical properties of ginkgo flavonoids,they can be separated and purified by resin adsorption,supercritical extraction and solvent methods.Previous studies have proved that ginkgo flavonoids have pharmacological functions in promoting blood circulation,anti-oxidation,anti-aging,improving memory,anti-tumor and liver protection,etc.Ginkgo flavonoids have been used clinically to treat angina pectoris,coronary heart disease,myocardial ischemia,hypertension,hyperlipidemia,diabetes,alzheimer's disease,atherosclerosis,gastric cancer and ovarian malignancy and other difficult miscellaneous diseases.展开更多
In a novel procedure, human serum albumin timctionalized magnetic nanoparticles （ HSA-MNPS ） were used to selectively extract nine flavonoids in the extract of Ginkgo biloba leaves. The chemical structures of those ...In a novel procedure, human serum albumin timctionalized magnetic nanoparticles （ HSA-MNPS ） were used to selectively extract nine flavonoids in the extract of Ginkgo biloba leaves. The chemical structures of those flavonoids were characterized with high performance liquid chromatography coupled with mass spectrometry （HPLC-MS）. The selective extraction with HSA-MNPs coupled with structural elucidation with HPLC-MS shows powerful potential for analysis of bioactive components in traditional Chinese medicines.展开更多
基金Natural Science Foundation Project of Hubei Province(2018CFB406)Talent Introduction Project of Hubei Polytechnic University(19XJK02R)Hubei Provincial Education Department Project(Q20204508).
文摘Ginkgo flavonoids are one of the most effective medicinal components extracted from leaves of Ginkgo biloba L.According to the physical and chemical properties of ginkgo flavonoids,they can be separated and purified by resin adsorption,supercritical extraction and solvent methods.Previous studies have proved that ginkgo flavonoids have pharmacological functions in promoting blood circulation,anti-oxidation,anti-aging,improving memory,anti-tumor and liver protection,etc.Ginkgo flavonoids have been used clinically to treat angina pectoris,coronary heart disease,myocardial ischemia,hypertension,hyperlipidemia,diabetes,alzheimer's disease,atherosclerosis,gastric cancer and ovarian malignancy and other difficult miscellaneous diseases.
基金Financial support from National Natural Science Foundation of China (Nos. 21072184 and 81173536)
文摘In a novel procedure, human serum albumin timctionalized magnetic nanoparticles （ HSA-MNPS ） were used to selectively extract nine flavonoids in the extract of Ginkgo biloba leaves. The chemical structures of those flavonoids were characterized with high performance liquid chromatography coupled with mass spectrometry （HPLC-MS）. The selective extraction with HSA-MNPs coupled with structural elucidation with HPLC-MS shows powerful potential for analysis of bioactive components in traditional Chinese medicines.
