In neurodegenerative diseases,neuroinflammatory responses are often activated in resident immune cells in the central nervous system（CNS）（Schroder and Tschopp,2010）.Optic neuropathy refers to dysfunction and degen...In neurodegenerative diseases,neuroinflammatory responses are often activated in resident immune cells in the central nervous system（CNS）（Schroder and Tschopp,2010）.Optic neuropathy refers to dysfunction and degeneration of retinal ganglion cells（RGCs）and their axons,which is often induced by optic nerve injury or glaucomatous insult.Studies,展开更多
Glaucoma is one of the leading causes of blindness in the developed world.It is a progressive optic neuropathy where structural loss of retinal ganglion cell（RGC）axons corresponds with functional visual field defect...Glaucoma is one of the leading causes of blindness in the developed world.It is a progressive optic neuropathy where structural loss of retinal ganglion cell（RGC）axons corresponds with functional visual field defect.Glaucoma is distinguished from other optic neuropathies by its selective loss of RGC axons.Superior and inferior peripheral nerve sectors are found to be most vulnerable to pressure induced injury whereas the inner temporal sector is most resilient（Quigley et al.,1988）.展开更多
Glaucoma is a group of degenerative retinal diseases that damage the eye’s optic nerve and can result in vision loss and blindness.It is characterized by optic neuropathy,cupping of the optic disk.
文摘In neurodegenerative diseases,neuroinflammatory responses are often activated in resident immune cells in the central nervous system（CNS）（Schroder and Tschopp,2010）.Optic neuropathy refers to dysfunction and degeneration of retinal ganglion cells（RGCs）and their axons,which is often induced by optic nerve injury or glaucomatous insult.Studies,
基金provided by the National Health and Medical Research Council of Australia
文摘Glaucoma is one of the leading causes of blindness in the developed world.It is a progressive optic neuropathy where structural loss of retinal ganglion cell（RGC）axons corresponds with functional visual field defect.Glaucoma is distinguished from other optic neuropathies by its selective loss of RGC axons.Superior and inferior peripheral nerve sectors are found to be most vulnerable to pressure induced injury whereas the inner temporal sector is most resilient（Quigley et al.,1988）.
文摘Glaucoma is a group of degenerative retinal diseases that damage the eye’s optic nerve and can result in vision loss and blindness.It is characterized by optic neuropathy,cupping of the optic disk.
