In this paper, we discuss a mathematical model of malaria transmission between vector and host population. We study the basic qualitative properties of the model, the boundedness and non-negativity, calculate all equi...In this paper, we discuss a mathematical model of malaria transmission between vector and host population. We study the basic qualitative properties of the model, the boundedness and non-negativity, calculate all equilibria, and prove the global stability of them and the behaviour of the model when the basic reproduction ratio R0 is greater than one or less than one. The global stability of equilibria is established by using Lyapunov method. Graphical representations of the calculated parameters and their effects on disease eradication are provided.展开更多
This paper develops an SIBR cholera transmission model with general incidence rate. Necessary and sufficient conditions for local and global asymptotic stability of the equilibria are established by Routh Hurwitz crit...This paper develops an SIBR cholera transmission model with general incidence rate. Necessary and sufficient conditions for local and global asymptotic stability of the equilibria are established by Routh Hurwitz criterium, Lyapunov function, and the second additive composite matrix theorem. What is more, exploiting the DED is cover simulation tool, the parameter values of the model are estimated with the 1998-2021 cholera case data in China. Finally, we perform sensitivity analysis for the basic reproduction number to seek for effective interventions for cholera control. .展开更多
In this paper we propose and analyze an HCV dynamics model taking into consideration the cure of infected hepatocytes and antibody immune response. We incorporate both virus-to-cell and cell-to-cell transmissions into...In this paper we propose and analyze an HCV dynamics model taking into consideration the cure of infected hepatocytes and antibody immune response. We incorporate both virus-to-cell and cell-to-cell transmissions into the model. We incorporate a distributed-time delay to describe the time between the HCV or infected cell contacts an uninfected hepatocyte and the emission of new active HCV. We show that the solutions of the proposed model are nonnegative and ultimately bounded. We derive two threshold parameters which fully determine the existence and stability of the three steady states of the model. Using Lyapunov functionals, we established the global stability of the steady states. The theoretical results are confirmed by numerical simulations.展开更多
In this paper,an attempt has been made to explore a new delayed epidemiological model assuming that the disease is transmitted among the susceptible population and possessing nonlinear incidence function along with a ...In this paper,an attempt has been made to explore a new delayed epidemiological model assuming that the disease is transmitted among the susceptible population and possessing nonlinear incidence function along with a saturated treatment rate.Due attention is paid to the positivity and boundedness of the solutions and the bifurcation of the dynamical system as well.Basic reproduction number is being calculated,and considering the latent period as a bifurcation parameter,it has been examined that a Hopf-bifurcation occurs near the endemic equilibrium point while the parameter attains critical values.We have also discussed the stability and direction of Hopf-bifurcation near the endemic equilibrium point,the global stability analysis and the optimal control theory.We conclude that the system reveals chaotic dynamics through a specific time-delay value.Numerical simulations are being performed in order to explain the accuracy and effectiveness of the acquired theoretical results.展开更多
文摘In this paper, we discuss a mathematical model of malaria transmission between vector and host population. We study the basic qualitative properties of the model, the boundedness and non-negativity, calculate all equilibria, and prove the global stability of them and the behaviour of the model when the basic reproduction ratio R0 is greater than one or less than one. The global stability of equilibria is established by using Lyapunov method. Graphical representations of the calculated parameters and their effects on disease eradication are provided.
文摘This paper develops an SIBR cholera transmission model with general incidence rate. Necessary and sufficient conditions for local and global asymptotic stability of the equilibria are established by Routh Hurwitz criterium, Lyapunov function, and the second additive composite matrix theorem. What is more, exploiting the DED is cover simulation tool, the parameter values of the model are estimated with the 1998-2021 cholera case data in China. Finally, we perform sensitivity analysis for the basic reproduction number to seek for effective interventions for cholera control. .
文摘In this paper we propose and analyze an HCV dynamics model taking into consideration the cure of infected hepatocytes and antibody immune response. We incorporate both virus-to-cell and cell-to-cell transmissions into the model. We incorporate a distributed-time delay to describe the time between the HCV or infected cell contacts an uninfected hepatocyte and the emission of new active HCV. We show that the solutions of the proposed model are nonnegative and ultimately bounded. We derive two threshold parameters which fully determine the existence and stability of the three steady states of the model. Using Lyapunov functionals, we established the global stability of the steady states. The theoretical results are confirmed by numerical simulations.
文摘In this paper,an attempt has been made to explore a new delayed epidemiological model assuming that the disease is transmitted among the susceptible population and possessing nonlinear incidence function along with a saturated treatment rate.Due attention is paid to the positivity and boundedness of the solutions and the bifurcation of the dynamical system as well.Basic reproduction number is being calculated,and considering the latent period as a bifurcation parameter,it has been examined that a Hopf-bifurcation occurs near the endemic equilibrium point while the parameter attains critical values.We have also discussed the stability and direction of Hopf-bifurcation near the endemic equilibrium point,the global stability analysis and the optimal control theory.We conclude that the system reveals chaotic dynamics through a specific time-delay value.Numerical simulations are being performed in order to explain the accuracy and effectiveness of the acquired theoretical results.
