Two new C-glucofuranosyl isoflavones of impurities in puerarin injection were isolated. Their structures were detemained to be 8-C-α-glucofuranosyl-7, 4P-dihydroxyisoflavone and 8-C-β-glucofuranosyl-7, 4＇-dihydroxy...Two new C-glucofuranosyl isoflavones of impurities in puerarin injection were isolated. Their structures were detemained to be 8-C-α-glucofuranosyl-7, 4P-dihydroxyisoflavone and 8-C-β-glucofuranosyl-7, 4＇-dihydroxy- isoflavone by chemical and spectral analysis.展开更多
The title compound,1,2:5,6 di-O-isopropylidene-α-D-glucofuranosyl N,N-bis(2-chloroethyl) N'-isopropylphosphordiamidate(C19H35O7N2PCl2),was synthesized by a series of reactions, and its crystal structure was deter...The title compound,1,2:5,6 di-O-isopropylidene-α-D-glucofuranosyl N,N-bis(2-chloroethyl) N'-isopropylphosphordiamidate(C19H35O7N2PCl2),was synthesized by a series of reactions, and its crystal structure was determined by single crystal X-ray diffraction.The crystal is the orthorhombic space group P212121 with α=9. 996(3),b=22.149(5),c=11.858(3)A,V=2647.4A,Mr=505.4,Z=4,Dx=1.27 g/cm3, μ=3.4 cm-1,and F(000)=1080.The structure was solved by direct methods(SHELXS 86).The final refinement converged with unweighted and weighted agreement factors of 0.068 and 0. 072 for 2230 observed independent reflections with I≥3σ(I).The results of structure analysis indicate that the configuration of the chiral phosphorus atom is R-form.展开更多
文摘Two new C-glucofuranosyl isoflavones of impurities in puerarin injection were isolated. Their structures were detemained to be 8-C-α-glucofuranosyl-7, 4P-dihydroxyisoflavone and 8-C-β-glucofuranosyl-7, 4＇-dihydroxy- isoflavone by chemical and spectral analysis.
文摘The title compound,1,2:5,6 di-O-isopropylidene-α-D-glucofuranosyl N,N-bis(2-chloroethyl) N'-isopropylphosphordiamidate(C19H35O7N2PCl2),was synthesized by a series of reactions, and its crystal structure was determined by single crystal X-ray diffraction.The crystal is the orthorhombic space group P212121 with α=9. 996(3),b=22.149(5),c=11.858(3)A,V=2647.4A,Mr=505.4,Z=4,Dx=1.27 g/cm3, μ=3.4 cm-1,and F(000)=1080.The structure was solved by direct methods(SHELXS 86).The final refinement converged with unweighted and weighted agreement factors of 0.068 and 0. 072 for 2230 observed independent reflections with I≥3σ(I).The results of structure analysis indicate that the configuration of the chiral phosphorus atom is R-form.
