目的探讨经皮胆囊穿刺引流(PTGD)后择期腹腔镜胆囊切除术治疗GradeⅡ急性结石性胆囊炎患者的效果。方法回顾性选取2017年8月至2020年6月尉氏县中心医院收治的52例行急诊腹腔镜胆囊切除术GradeⅡ急性结石性胆囊炎患者(对照组)及52例行PTG...目的探讨经皮胆囊穿刺引流(PTGD)后择期腹腔镜胆囊切除术治疗GradeⅡ急性结石性胆囊炎患者的效果。方法回顾性选取2017年8月至2020年6月尉氏县中心医院收治的52例行急诊腹腔镜胆囊切除术GradeⅡ急性结石性胆囊炎患者(对照组)及52例行PTGD后择期腹腔镜胆囊切除术GradeⅡ急性结石性胆囊炎患者(观察组),比较两组手术时间、术中出血量、术后肛门排气时间、术后引流时间、术后住院时间、炎症指标[白细胞(WBC)、中性粒细胞、C反应蛋白(CRP)]、血清淀粉酶(AMY)、肝功能指标[丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、直接胆红素(DBIL)、间接胆红素(IBIL)]、中转开腹及安全性。结果观察组手术时间、术中出血量、术后引流时间、术后住院时间短于对照组(P<0.05);观察组术后72 h WBC、中性粒细胞、CRP低于对照组(P<0.05);观察组术后72 h AMY低于对照组(P<0.05);观察组无中转开腹发生,中转开腹率低于对照组(P<0.05);观察组并发症发生率为3.85%(2/52),低于对照组的15.38%(8/52)(P<0.05)。结论PTGD后择期腹腔镜胆囊切除术治疗GradeⅡ急性结石性胆囊炎,能减少术中出血量,缩短术后引流时间和住院时间,降低中转开腹率,并能促进胆囊炎症消退,安全性高。展开更多
Objective:To investigate the effect and value of perioperative nursing intervention on postoperative recurrent grade II-I left frontal astrocytoma.Method:Nursing care procedures:left frontal lobe of the patient was oc...Objective:To investigate the effect and value of perioperative nursing intervention on postoperative recurrent grade II-I left frontal astrocytoma.Method:Nursing care procedures:left frontal lobe of the patient was occupied by a large space.Clinical teaching of nursing was strengthened.Preoperative,intraoperative and postoperative care and ward patrol were enhanced.Close attention was paid on consciousness,pupil,vital signs,body temperature,lungs condition,cranial and nerve function of the patient.Extra care was taken in keeping the incision clean and dry.Blood diffusion condition in wound was observed.Active cooperation with doctor was taken to prevent occurrence of pulmonary infection,urinary tract infection,pressure ulcer and other complication.Results:After operation,the patient had stable condition,clear mind and consciousness.There was no occurrence of epilepsy but intracranial hemorrhage.Pneumatosis was relieved.There was no infection and other complication.Conclusion:Application of comprehensive nursing intervention could effectively improve quality of life of patient and reduce incidence of postoperative complication in patients with brain tumor.展开更多
目的 探讨血清甲胎蛋白(alpha-fetoprotein,AFP)、异常凝血酶原(protein induced by vitamin K absence antagonist-Ⅱ,PIVKA-Ⅱ)和微小RNA-21(microRNA-21,miR-21)检测对肝细胞癌(hepatocellular carcinoma,HCC)的诊断意义。方法 筛选2...目的 探讨血清甲胎蛋白(alpha-fetoprotein,AFP)、异常凝血酶原(protein induced by vitamin K absence antagonist-Ⅱ,PIVKA-Ⅱ)和微小RNA-21(microRNA-21,miR-21)检测对肝细胞癌(hepatocellular carcinoma,HCC)的诊断意义。方法 筛选2017年12月至2018年6月在天津市第二人民医院住院的代偿期肝硬化患者,经肝脏钆塞酸二钠增强MRI检查,纳入临床诊断为HCC、肝硬化伴高度异型增生结节(high-grade dysplastic nodules,HGDN)及肝硬化伴再生结节(regenerativenodule,RN)的患者共90例,分为HCC组、HGDN组及RN组,每组30例。收集血清检测AFP、PIVKA-Ⅱ及miR-21水平。采用Kruskal-Wallis H检验比较组间差异,Bonferroni法校正显著性水平后进一步两两比较,通过二元logistic回归建立三种指标联合模型APR,采用受试者工作特征曲线下面积(the area under the receiver operating characteristic curve,AUC)评估AFP、PIVKA-Ⅱ、miR-21及联合模型APR对HCC的诊断效能。结果 AFP、PIVKA-Ⅱ水平在RN组和HGDN组间无差异,但HCC组高于HGDN组和RN组,差异有统计学意义(校正后P <0.05);miR-21水平在RN组、HGDN组及HCC组间逐渐升高,差异有统计学意义(校正后P <0.05)。单项检测诊断HCC时,AFP的特异度为91.7%,敏感度为53.3%;PIVKA-Ⅱ的特异度为93.3%,敏感度为66.7%;miR-21的敏感度为97.1%,特异度为85.0%。三种指标联合模型APR的敏感度和特异度分别为93.3%、91.7%。AFP、PIVKA-Ⅱ、miR-21及联合模型APR对HCC诊断的AUC分别为0.756、0.873、0.953和0.963。结论 血清AFP、PIVKA-Ⅱ、 miR-21对HCC有较高的诊断价值,但单项检测时各有不足,三者联合检测有助于HCC的诊断筛查。展开更多
文摘目的探讨经皮胆囊穿刺引流(PTGD)后择期腹腔镜胆囊切除术治疗GradeⅡ急性结石性胆囊炎患者的效果。方法回顾性选取2017年8月至2020年6月尉氏县中心医院收治的52例行急诊腹腔镜胆囊切除术GradeⅡ急性结石性胆囊炎患者(对照组)及52例行PTGD后择期腹腔镜胆囊切除术GradeⅡ急性结石性胆囊炎患者(观察组),比较两组手术时间、术中出血量、术后肛门排气时间、术后引流时间、术后住院时间、炎症指标[白细胞(WBC)、中性粒细胞、C反应蛋白(CRP)]、血清淀粉酶(AMY)、肝功能指标[丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、直接胆红素(DBIL)、间接胆红素(IBIL)]、中转开腹及安全性。结果观察组手术时间、术中出血量、术后引流时间、术后住院时间短于对照组(P<0.05);观察组术后72 h WBC、中性粒细胞、CRP低于对照组(P<0.05);观察组术后72 h AMY低于对照组(P<0.05);观察组无中转开腹发生,中转开腹率低于对照组(P<0.05);观察组并发症发生率为3.85%(2/52),低于对照组的15.38%(8/52)(P<0.05)。结论PTGD后择期腹腔镜胆囊切除术治疗GradeⅡ急性结石性胆囊炎,能减少术中出血量,缩短术后引流时间和住院时间,降低中转开腹率,并能促进胆囊炎症消退,安全性高。
文摘Objective:To investigate the effect and value of perioperative nursing intervention on postoperative recurrent grade II-I left frontal astrocytoma.Method:Nursing care procedures:left frontal lobe of the patient was occupied by a large space.Clinical teaching of nursing was strengthened.Preoperative,intraoperative and postoperative care and ward patrol were enhanced.Close attention was paid on consciousness,pupil,vital signs,body temperature,lungs condition,cranial and nerve function of the patient.Extra care was taken in keeping the incision clean and dry.Blood diffusion condition in wound was observed.Active cooperation with doctor was taken to prevent occurrence of pulmonary infection,urinary tract infection,pressure ulcer and other complication.Results:After operation,the patient had stable condition,clear mind and consciousness.There was no occurrence of epilepsy but intracranial hemorrhage.Pneumatosis was relieved.There was no infection and other complication.Conclusion:Application of comprehensive nursing intervention could effectively improve quality of life of patient and reduce incidence of postoperative complication in patients with brain tumor.
文摘目的 探讨血清甲胎蛋白(alpha-fetoprotein,AFP)、异常凝血酶原(protein induced by vitamin K absence antagonist-Ⅱ,PIVKA-Ⅱ)和微小RNA-21(microRNA-21,miR-21)检测对肝细胞癌(hepatocellular carcinoma,HCC)的诊断意义。方法 筛选2017年12月至2018年6月在天津市第二人民医院住院的代偿期肝硬化患者,经肝脏钆塞酸二钠增强MRI检查,纳入临床诊断为HCC、肝硬化伴高度异型增生结节(high-grade dysplastic nodules,HGDN)及肝硬化伴再生结节(regenerativenodule,RN)的患者共90例,分为HCC组、HGDN组及RN组,每组30例。收集血清检测AFP、PIVKA-Ⅱ及miR-21水平。采用Kruskal-Wallis H检验比较组间差异,Bonferroni法校正显著性水平后进一步两两比较,通过二元logistic回归建立三种指标联合模型APR,采用受试者工作特征曲线下面积(the area under the receiver operating characteristic curve,AUC)评估AFP、PIVKA-Ⅱ、miR-21及联合模型APR对HCC的诊断效能。结果 AFP、PIVKA-Ⅱ水平在RN组和HGDN组间无差异,但HCC组高于HGDN组和RN组,差异有统计学意义(校正后P <0.05);miR-21水平在RN组、HGDN组及HCC组间逐渐升高,差异有统计学意义(校正后P <0.05)。单项检测诊断HCC时,AFP的特异度为91.7%,敏感度为53.3%;PIVKA-Ⅱ的特异度为93.3%,敏感度为66.7%;miR-21的敏感度为97.1%,特异度为85.0%。三种指标联合模型APR的敏感度和特异度分别为93.3%、91.7%。AFP、PIVKA-Ⅱ、miR-21及联合模型APR对HCC诊断的AUC分别为0.756、0.873、0.953和0.963。结论 血清AFP、PIVKA-Ⅱ、 miR-21对HCC有较高的诊断价值,但单项检测时各有不足,三者联合检测有助于HCC的诊断筛查。
