Background:Neglected tropical diseases(NTDs)are an important cause of death and disability in Africa.This study estimates the monetary value of human lives lost due to NTDs in the continent in 2015.Methods:The lost ou...Background:Neglected tropical diseases(NTDs)are an important cause of death and disability in Africa.This study estimates the monetary value of human lives lost due to NTDs in the continent in 2015.Methods:The lost output or human capital approach was used to evaluate the years of life lost due to premature deaths from NTDs among 10 high/upper-middle-income(Group 1),17 middle-income(Group 2)and 27 low-income(Group 3)countries in Africa.The future losses were discounted to their present values at a 3%discount rate.The model was re-analysed using 5%and 10%discount rates to assess the impact on the estimated total value of human lives lost.Results:The estimated value of 67860 human lives lost in 2015 due to NTDs was Int$5112472607.Out of that,14.6%was borne by Group 1,57.7%by Group 2 and 27.7%by Group 3 countries.The mean value of human life lost per NTD death was Int$231278,Int$109771 and Int$37489 for Group 1,Group 2 and Group 3 countries,respectively.The estimated value of human lives lost in 2015 due to NTDs was equivalent to 0.1%of the cumulative gross domestic product of the 53 continental African countries.Conclusions:Even though NTDs are not a major cause of death,they impact negatively on the productivity of those affected throughout their life-course.Thus,the case for investing in NTDs control should also be influenced by the value of NTD morbidity,availability of effective donated medicines,human rights arguments,and need to achieve the NTD-related target 3.3 of the United Nations Sustainable Development Goal 3(on health)by 2030.展开更多
基金This research received no specific grant from any funding agency in the public,commercial or not-for-profit sectors。
文摘Background:Neglected tropical diseases(NTDs)are an important cause of death and disability in Africa.This study estimates the monetary value of human lives lost due to NTDs in the continent in 2015.Methods:The lost output or human capital approach was used to evaluate the years of life lost due to premature deaths from NTDs among 10 high/upper-middle-income(Group 1),17 middle-income(Group 2)and 27 low-income(Group 3)countries in Africa.The future losses were discounted to their present values at a 3%discount rate.The model was re-analysed using 5%and 10%discount rates to assess the impact on the estimated total value of human lives lost.Results:The estimated value of 67860 human lives lost in 2015 due to NTDs was Int$5112472607.Out of that,14.6%was borne by Group 1,57.7%by Group 2 and 27.7%by Group 3 countries.The mean value of human life lost per NTD death was Int$231278,Int$109771 and Int$37489 for Group 1,Group 2 and Group 3 countries,respectively.The estimated value of human lives lost in 2015 due to NTDs was equivalent to 0.1%of the cumulative gross domestic product of the 53 continental African countries.Conclusions:Even though NTDs are not a major cause of death,they impact negatively on the productivity of those affected throughout their life-course.Thus,the case for investing in NTDs control should also be influenced by the value of NTD morbidity,availability of effective donated medicines,human rights arguments,and need to achieve the NTD-related target 3.3 of the United Nations Sustainable Development Goal 3(on health)by 2030.