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0.025-inch vs 0.035-inch guide wires for wire-guided cannulation during endoscopic retrograde cholangio pancreatography:A randomized study 被引量:1
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作者 Katsuya Kitamura Akira Yamamiya +5 位作者 Yu Ishii Yoshiki Sato Tomoyuki Iwata Tomohiro Nomoto Akitoshi Ikegami Hitoshi Yoshida 《World Journal of Gastroenterology》 SCIE CAS 2015年第30期9182-9188,共7页
AIM:To compare the clinical outcomes between 0.025-inch and 0.035-inch guide wires(GWs) when used in wire-guided cannulation(WGC).METHODS:A single center,randomized study was conducted between April 2011 and March 201... AIM:To compare the clinical outcomes between 0.025-inch and 0.035-inch guide wires(GWs) when used in wire-guided cannulation(WGC).METHODS:A single center,randomized study was conducted between April 2011 and March 2013. This study was approved by the Medical Ethics Committee at our hospital. Informed,written consent was obtained from each patient prior to study enrollment. Three hundred and twenty-two patients with a na?ve papilla of Vater who underwent endoscopic retrograde cholangiopancreatography(ERCP) for the purpose of selective bile duct cannulation with WGC were enrolled in this study. Fifty-three patients were excluded based on the exclusion criteria,and 269 patients were randomly allocated to two groups by a computer and analyzed:the 0.025-inch GW group(n = 109) and the 0.035-inch GW group(n = 160). The primary endpoint was the success rate of selective bile duct cannulation with WGC. Secondary endpoints were the success rates of the pancreatic GW technique and precutting,selective bile duct cannulation time,ERCP procedure time,the rate of pancreatic duct stent placement,the final success rate of selective bile duct cannulation,andthe incidence of post-ERCP pancreatitis(PEP).RESULTS:The primary success rates of selective bile duct cannulation with WGC were 80.7%(88/109) and 86.3%(138/160) for the 0.025-inch and the 0.035-inch groups,respectively(P = 0.226). There were no statistically significant differences in the success rates of selective bile duct cannulation using the pancreatic duct GW technique(46.7% vs 52.4% for the 0.025-inch and 0.035-inch groups,respectively; P = 0.884) or in the success rates of selective bile duct cannulation using precutting(66.7% vs 63.6% for the 0.025-inch and 0.035-inch groups,respectively; P = 0.893). The final success rates for selective bile duct cannulation using these procedures were 92.7%(101/109) and 97.5%(156/160) for the 0.025-inch and 0.035-inch groups,respectively(P = 0.113). There were no significant differences in selective bile duct cannulation time(median ± interquartile range:3.7 ± 13.9 min vs 4.0 ± 11.2 min for the 0.025-inch and 0.035-inch groups,respectively; P = 0.851),ERCP procedure time(median ± interquartile range:32 ± 29 min vs 30 ± 25 min for the 0.025-inch and 0.035-inch groups,respectively; P = 0.184) or in the rate of pancreatic duct stent placement(14.7% vs 15.6% for the 0.025-inch and 0.035-inch groups,respectively; P = 0.832). The incidence of PEP was 2.8%(3/109) and 2.5%(4/160) for the 0.025-inch and 0.035-inch groups,respectively(P = 0.793).CONCLUSION:The thickness of the GW for WGC does not appear to affect either the success rate of selective bile duct cannulation or the incidence of PEP. 展开更多
关键词 ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY guide wire Post-endoscopic retrogradecholangiopancreatography pancreatitis Selective bileduct CANNULATION wire-guided CANNULATION
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Newly designed J-shaped tip guidewire: A preliminary feasibility study in wire-guided cannulation 被引量:1
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作者 Shigefumi Omuta Iruru Maetani +4 位作者 Hiroaki Shigoka Katsushige Gon Michihiro Saito Junya Tokuhisa Mieko Naruki 《World Journal of Gastroenterology》 SCIE CAS 2013年第28期4531-4536,共6页
AIM: To perform wire-guided cannulation using a newly designed J-shaped tip guidewire, and to verify feasibility and safety for use. METHODS: The study was conducted on endoscopic retrograde cholangiopancreatography (... AIM: To perform wire-guided cannulation using a newly designed J-shaped tip guidewire, and to verify feasibility and safety for use. METHODS: The study was conducted on endoscopic retrograde cholangiopancreatography (ERCP) patients with na ve papilla undergoing diagnosis and treatment of biliary diseases between September 2011 and July 2012. We performed ERCP in a succession of 50 cases with a J-shaped tip guidewire. The first insertion attempt began with a trainee who had 5 min to complete cannulation, followed if necessary by the trainer for another 5 min. We assessed the primary success rate of selective biliary cannulation within 10 min and adverse events such as post-ERCP pancreatitis (PEP), bleeding or perforation.RESULTS: The primary success rate was 90% (45/50) within 10 min, the initial success rate within 5 min by trainee staff was 76% (38/50). The rate of PEP was 6% (3/50), but all 3 cases were mild pancreatitis. All patients were managed successfully with conservative treatment. There was no bleeding or perforation. CONCLUSION: A newly designed J-shaped tip guidewire has the possibility to facilitate selective biliary cannulation for ERCP and appears to be safe. 展开更多
关键词 J-SHAPED TIP guidEwire wire-guided CANNULATION Endoscopic retrograde cholangiopancreatography Biliary tract CANNULATION technique Perforation
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VIRTUAL REALITY BASED THREE-DIMENSIONAL GUIDE WIRE PROPAGATION SIMULATION FOR ENDOVASCULAR INTERVENTION 被引量:3
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作者 周正东 Pascal Haigron +1 位作者 Vincent Guilloux Antoine Lucas 《Transactions of Nanjing University of Aeronautics and Astronautics》 EI 2010年第1期62-69,共8页
The virtual reality based motion simulation of the guide wire and the catheter inside specific vascular structures can benefit a lot for the endovascular intervention. A fast and well-performed collision cancellation ... The virtual reality based motion simulation of the guide wire and the catheter inside specific vascular structures can benefit a lot for the endovascular intervention. A fast and well-performed collision cancellation algorithm is proposed based on the geometric analysis and the angular propagation (AP), and a 3-D real-time interactive system is developed for the motion simulation of the guide wire and the catheter inside the specific patient vascular. The guide wire or the catheter is modeled as the "multi-body" representation and properties are defined by its intrinsic characteristics. The motion of the guide wire or the catheter inside the vascular is guided by the collision detection and the collision cancellation algorithm. Finally, a relaxation procedure is used to achieve more realistic status. Experimental results show that the behavior of the guide wire or the catheter depends on the defined parameters. The real-time simulation can be achieved. The result shows that the simulation system is effective and promising. 展开更多
关键词 CATHETERS virtual reality guide wire multi-body model endovascular intervention
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电磁导航支气管镜引导下肺结节定位和CT引导下Hook-wire穿刺定位在肺癌根治术中的应用效果及安全性比较
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作者 郑晓东 聂世威 +2 位作者 周军正 岳光成 张卫民 《癌症进展》 2024年第16期1814-1817,共4页
目的对比电磁导航支气管镜(ENB)引导下肺结节定位和CT引导下Hook-wire穿刺定位在肺癌根治术中的应用效果和安全性。方法将87例行肺癌根治术患者根据定位方式的不同分为CT组(n=45,行CT引导下Hook-wire穿刺定位)和ENB组(n=42,行ENB引导下... 目的对比电磁导航支气管镜(ENB)引导下肺结节定位和CT引导下Hook-wire穿刺定位在肺癌根治术中的应用效果和安全性。方法将87例行肺癌根治术患者根据定位方式的不同分为CT组(n=45,行CT引导下Hook-wire穿刺定位)和ENB组(n=42,行ENB引导下肺结节定位)。比较两组患者手术情况、切缘阳性率、心肺功能指标、应激指标和并发症发生情况。结果ENB组患者定位时间、定位后等待时间均短于CT组,差异均有统计学意义(P﹤0.05)。术后7天,两组患者左心室射血分数(LVEF)、每搏量(SV)、用力肺活量(FVC)均较术前降低,但ENB组患者LVEF、SV、FVC均高于CT组,差异均有统计学意义(P﹤0.05)。术后1天,两组患者白细胞介素-6(IL-6)、白细胞介素-8(IL-8)、C反应蛋白(CRP)、皮质醇(Cor)水平均较术前升高,但ENB组患者IL-6、IL-8、CRP、Cor水平均低于CT组,差异均有统计学意义(P﹤0.05)。两组患者并发症总发生率比较,差异无统计学意义(P﹥0.05)。结论相比于CT引导下Hook-wire穿刺定位,ENB引导下肺结节定位的定位时间和定位后等待时间更短,能够更加有效地改善患者的心肺功能,减轻应激反应。 展开更多
关键词 电磁导航支气管镜引导下肺结节定位 CT引导下Hook-wire穿刺定位 肺癌根治术 定位时间
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FEM model for real-time guide wire simulation in vasculature
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作者 张秋葵 Pascal Haigron +1 位作者 罗立民 舒华忠 《Journal of Southeast University(English Edition)》 EI CAS 2008年第1期50-54,共5页
A model suitable for describing the mechanical response of thin elastic objects is proposed to simulate the deformation of guide wires in minimally invasive interventions. The main objective of this simulation is to p... A model suitable for describing the mechanical response of thin elastic objects is proposed to simulate the deformation of guide wires in minimally invasive interventions. The main objective of this simulation is to provide doctors an opportunity to rehearse the surgery and select an optimal operation plan before the real surgery. In this model the guide wire is discretized with the multi-body representation and its elastic energy derivate from elastic theory is a polynomial function of the nodal displacements. The vascular structure is represented by a tetrahedron mesh extended from the triangular mesh of the artery, which can be extracted from the patient's CT image data. The model applies the energy decline process of the conjugate gradient method to the deformation simulation of the guide wire. Experimental results show that the polynomial relationship between elastic energy and nodal displacements tremendously simplifies the evaluation of the conjugate gradient method and significantly improves the model's efficiency. Compared with models depending on an explicit scheme for evaluation, the new model is not only non-conditionally stable but also more efficient. The model can be applied to the real-time simulation of guide wire in a vascular structure. 展开更多
关键词 deformable model finite element method real-time simulation guide wire
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CT引导下Hook-wire定位辅助胸腔镜手术对早期肺癌患者的疗效分析
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作者 孔建峰 《实用癌症杂志》 2024年第2期255-258,共4页
目的探讨CT引导下Hook-wire定位辅助胸腔镜手术对早期肺癌患者的疗效。方法选取92例早期肺癌患者,按随机数字表法分为两组,各46例。对照组行常规胸腔镜手术治疗,观察组行CT引导下Hook-wire定位辅助胸腔镜手术治疗。比较两组手术情况、... 目的探讨CT引导下Hook-wire定位辅助胸腔镜手术对早期肺癌患者的疗效。方法选取92例早期肺癌患者,按随机数字表法分为两组,各46例。对照组行常规胸腔镜手术治疗,观察组行CT引导下Hook-wire定位辅助胸腔镜手术治疗。比较两组手术情况、创伤应激指标、肿瘤标志物水平及并发症。结果观察组手术时间、术后引流时间及住院时间为(138.52±10.52)min、(3.12±0.45)d、(10.35±1.25)d,短于对照组,术中出血量为(105.41±12.36)ml,少于对照组,差异有统计学意义(P<0.05);观察组术后皮质醇(Cor)、去甲肾上腺素(NE)、C反应蛋白(CRP)水平分别为(118.52±8.36)ng/ml、(185.93±14.52)ng/L、(32.41±4.25)mg/L,低于对照组,差异有统计学意义(P<0.05);观察组术后癌胚抗原(CEA)、细胞角蛋白19片段抗原21-1(CYFRA21-1)、糖类抗原125(CA125)水平为(8.96±1.15)ng/ml、(3.88±0.42)ng/ml、(12.63±1.54)U/ml,低于对照组,并发症少于对照组,差异有统计学意义(P<0.05)。结论CT引导下Hook-wire定位辅助胸腔镜手术治疗早期肺癌效果更佳,可减轻手术创伤,降低创伤应激反应,加快肿瘤标志物复常,减少并发症发生。 展开更多
关键词 早期肺癌 CT引导 Hook-wire定位 胸腔镜手术 创伤应激指标 肿瘤标志物
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Sphincterotomy by triple lumen needle knife using guide wire in patients with Billroth Ⅱ gastrectomy
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作者 Su Bum Park Hyung Wook Kim +4 位作者 Dae Hwan Kang Cheol Woong Choi Ki Tae Yoon Mong Cho Byeong Jun Song 《World Journal of Gastroenterology》 SCIE CAS 2013年第48期9405-9409,共5页
AIM:To investigate the usefulness of a guide wire and triple lumen needle knife for removing stones in BillrothⅡ(B-Ⅱ)gastrectomy patients.METHODS:Endoscopic sphincterotomy in patients with B-Ⅱgastrectomy is challen... AIM:To investigate the usefulness of a guide wire and triple lumen needle knife for removing stones in BillrothⅡ(B-Ⅱ)gastrectomy patients.METHODS:Endoscopic sphincterotomy in patients with B-Ⅱgastrectomy is challenging.We used a new guide wire technique involving sphincterotomy by triple lumen needle knife through a forward-viewing endoscopy.This technique was performed in nine patients between August 2010 and June 2012.Sphincterotomy as described above was performed.Adequate sphincterotomy,successful stone removal,and complications were investigated prospectively.RESULTS:Sphincterotomy by triple lumen needle knife using guide wire was successful in all nine patients.Sphincterotomy started towards the 4-5 o’clock direction and continued to the upper margin of the papillary roof.Complete stone removal in one session was achieved in all patients.There were no procedure related complications,such as bleeding,pancreatitis,or perforation.CONCLUSION:In patients with B-Ⅱgastrectomy,guide wire using sphincterotomy by triple lumen needle knife through a forward-viewing endoscopy seems to be an effective and safe procedure for the removal of common bile duct stones. 展开更多
关键词 BILLROTH GASTRECTOMY Endoscopic SPHINCTEROTOMY Forward-viewing endoscopy guide wire Triple LUMEN NEEDLE KNIFE
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Open Surgical Insertion of Tenkchoff Straight Catheter Without Guide Wire
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作者 Shi-feng Yang Wu-jun Xue +2 位作者 Ai-ping Yin Li-yi Xie Wan-hong Lu 《Chinese Medical Sciences Journal》 CAS CSCD 2013年第2期117-121,共5页
Objective To compare the clinical outcomes of open surgical peritoneal dialysis catheter (PDC) insertion with guide wire and the outcomes of PDC insertion without guide wire. Methods Data of the patients receiving ... Objective To compare the clinical outcomes of open surgical peritoneal dialysis catheter (PDC) insertion with guide wire and the outcomes of PDC insertion without guide wire. Methods Data of the patients receiving open surgical Tenkchoff straight catheter insertion in our department from January 2005 to January 2011 were retrospectively analyzed. The 117 patients in whom PDC insertion was conducted with the guidance of guide wire were enrolled into group A, and the 121 cases receiving PDC insertion without guide wire were enrolled into group B. The incidences of post-operative complications (catheter obstruction, catheter displacement, bloody dialysate, and dialysate leakage), catheter survival, and patient survival rates were compared between the 2 groups. Results The baseline characteristics (gender, age, body mass index, prothrombin time, activated partial thromboplastin time, platelet count, serum creatinine, follow-up time, primary diseases, and outcomes) of the 2 groups were comparable (all P〉0.05). In post-operative complications, only the incidence of early bloody dialysate showed significant difference, being 16.2% in group A and 7.4% in group B (P=0.04). Catheter and patient survival rates were not significantly different between the two groups. Overweight patients showed a higher incidence of catheter obstruction compared with normal weight patients [16.0% (4/25) vs. 3.3% (7/213), P=0.02], but no differences in post-operative between the 2 groups. complications were found among overweight patients Conclusions Open surgical Tenkchoff straight catheter insertion without guide wire does not lead to higher risk of post-operative complications and catheter removal. It may be an alternative option when guide wire is not available. 展开更多
关键词 peritoneal dialysis CATHETERS SURGERY guide wire
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Accidental Migration of a Guide Wire during Femoral Venous Catheterization for Hemodialysis: A Case Report
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作者 Faye Moustapha Cisse Mouhamadou Moustapha +9 位作者 Faye Maria Daher Abdoul Karim Omar Lemrabott Ahmed Tall Fall Khodia Sakho Binta Keita Alex Mbengue Mansour Niang Abdou Diouf Boucar Ka Elhadji Fary 《Open Journal of Nephrology》 2018年第2期38-41,共4页
Femoral venous catheterization is the most used technic in emergency he-modialysis. Some uncommon mechanical complications can occur during a catheterization. We report the case of an accidental migration of a guide w... Femoral venous catheterization is the most used technic in emergency he-modialysis. Some uncommon mechanical complications can occur during a catheterization. We report the case of an accidental migration of a guide wire during the placement of a hemodialysis femoral catheter. The case of a patient admitted in the nephrology department at Aristide Le Dantec University Hospital for malignant hypertension was investigated. Emergency hemodialysis was indicated. Surgical extraction of the metal guide has been performed and the outcome was favorable. 展开更多
关键词 HEMODIALYSIS CATHETER COMPLICATION guide wire MIGRATION
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Choice PTTM guidewire for recanalization of total occlusive coronary arteries
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作者 欧阳平 何世华 +1 位作者 陈伟康 胡嘉儿 《Journal of Medical Colleges of PLA(China)》 CAS 2002年第3期206-209,共4页
Objective: To evaluate the therapeutic effects of 0. 014' Choice PTTM wire in chronic total occlusion angioplasty. Methods: Balloon angioplasty was attempted in 25 arteries with chronic total occlusion, with the m... Objective: To evaluate the therapeutic effects of 0. 014' Choice PTTM wire in chronic total occlusion angioplasty. Methods: Balloon angioplasty was attempted in 25 arteries with chronic total occlusion, with the mean time of occlusion of 17±13 months (ranging from 2 to 84 months) and mean length of 14±6 mm (ranging from 5 to 25 mm). The morphology of the lesions included bridging collaterals (4 cases), calcification (3 cases) and major side branch at the lesion (4 cases) . Choice PT?wire was used electively in all the cases. Results: Lesion was crossed successfully in 92% (23/25) cases, without incidences of dissection of the coronary artery with subintimal entry. Balloon angioplasy and stenting (n = 21) were performed with good immediate angiograghic results. Acute myocardial infarction or death occurred in none of the patients. Conclusion Successful recanalization of chronic coronary total occlusions using Choice PTTM wire can be achieved with good safety. 展开更多
关键词 chronic total occlusions ANGIOPLASTY guide wire
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Influence on Visibility Due to Differences of Guide Wire Movement―Visual &Physical Evaluations
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作者 Hisaya Sato Daisuke Kittaka +1 位作者 Miwa Ohsawa Kyoichi Kato 《Open Journal of Applied Sciences》 2020年第10期577-591,共15页
The visibility of moving images during cardiac catheterization and treatment may be reduced by a number of factors. First, it involves multiple movements that occur simultaneously, such as the movements due to the hea... The visibility of moving images during cardiac catheterization and treatment may be reduced by a number of factors. First, it involves multiple movements that occur simultaneously, such as the movements due to the heart beat and movement of the guide wire used during the treatment. There is also the influence of the X-ray dose on the image quality in the X-ray output. If X-rays are irradiated onto moving objects such as a guide wire moving during treatment of the heart, cardiac catheterization may be displaced to the next image recorded even when an insufficient X-ray dose has been irradiated because the imaged object is moving during the time the X-rays are emitted (pulse width). If the X-ray dose planned to be irradiated to the target is low, there is also the possibility that noise will appear in the image, and the imaged object may be lost in noise and visibility be reduced. For this reason, we conducted basic research into how changes in the speed of rotation of guide wires affect visibility when wires are positioned horizontally and vertically, using a dynamic phantom and recorded X-ray moving images. The purpose of this study is to elucidate whether the deterioration in the visibility is affected by the X-ray dose, the orientation or movement of a guide wire, or caused by other conditions, in order to contribute to improving the visibility in the X-ray moving images. The results showed a lower visual evaluation only in the vertical direction at the more rapid movement here, but this did not result in significant changes in the physical evaluation. This suggests that the structure and characteristics of the human eyes would be involved, as human vision is stronger with lateral movements and weaker with vertical movements due to the arrangement of the human eyes, side by side. Findings from this basic study can be utilized to improve the visibility in the X-ray moving images by paying attention to the observation environment of the observer of the X-ray moving images. In addition, the findings of this study can also be used to determine protocols for improving visibility in X-ray moving images, such as adjusting the X-ray dose in an X-ray device when further improvement is required. Therefore, this study was able to provide suggestions to contribute to the development of improved visibility of X-ray moving images. 展开更多
关键词 X-Ray Moving Images VISIBILITY Human Vision guide wire
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Difficult case of a trans-septal puncture: Use of a “SafeSept” guidewire
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作者 Martina Zucchetti Michela Casella +6 位作者 Antonio Dello Russo Gaetano Fassini Corrado Carbucicchio Eleonora Russo Vittoria Marino Valentina Catto Claudio Tondo 《World Journal of Cardiology》 CAS 2015年第8期499-503,共5页
A 69-year-old man was admitted to our center to undergo catheter ablation of paroxysmal atrial fibrillation refractory to antiarrhythmic drug therapy. This procedure required access to the left atrium through the inte... A 69-year-old man was admitted to our center to undergo catheter ablation of paroxysmal atrial fibrillation refractory to antiarrhythmic drug therapy. This procedure required access to the left atrium through the interatrial septum. During hospitalization, the patient performed routinely pre-procedure transthoracic echocardiography and gadolinium-enhanced cardiac magnetic resonance showing a normal anatomy of both the fossa ovalis and the interatrial septum. Access to the left atrium proved difficult and several unsuccessful attempts to perform the trans-septal puncture were made under both fluoroscopy and intracardiac echocardiography guidance, even with radiofrequency energy delivery. Finally, trans-septal puncture was successfully carried out using a novel nitinol J-shaped "Safe Sept" trans-septal guidewire, designed to cross the interatrial septum through the trans-septal needle thanks to a special sharp tip. Moreover, thanks to its rounded J shape that reduces the risk of atrial perforation, the "Safe Sept" guidewire, when advanced into the left atrium, becomes atraumatic. 展开更多
关键词 Trans-septal PUNCTURE "Safe Sept" guide-wire Atrial fibrillation Interatrial SEPTUM INTRACARDIAC echocardiography
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肺小结节术前CT引导下Hook-wire定位的临床应用 被引量:24
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作者 闾夏轶 杨运海 +1 位作者 胡坚 倪一鸣 《中国肺癌杂志》 CAS 2011年第5期418-420,共3页
背景与目的胸腔镜术中对于直径<1cm的肺小结节较难准确定位。数年前即有学者开始尝试使用各种方法进行术前的肺小结节定位。本文从适应症、结果、并发症三个方面回顾性分析了胸腔镜术前CT引导下Hook-wire定位的临床应用价值。方法 2... 背景与目的胸腔镜术中对于直径<1cm的肺小结节较难准确定位。数年前即有学者开始尝试使用各种方法进行术前的肺小结节定位。本文从适应症、结果、并发症三个方面回顾性分析了胸腔镜术前CT引导下Hook-wire定位的临床应用价值。方法 2010年1月-2010年4月,20例患者于胸腔镜术前接受了CT引导下肺小结节Hook-wire定位。小结节直径从0.5cm-2cm(平均9.8cm±5.3cm)。评价指标包括定位成功率,定位相关并发症,中转开胸比率等。结果 20例患者中18例定位成功,CT定位花费时间平均为14.5min,全组无严重并发症发生。结论胸腔镜术前CT引导下肺小结节Hook-wire定位有一定的临床应用价值,可帮助术中精确定位肺小结节位置,并且并发症发生率较低。 展开更多
关键词 CT引导 HOOK-wire 肺结节
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CT引导下Hook-wire精确定位并微创切除肺结节 被引量:33
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作者 王通 马少华 +4 位作者 闫天生 宋金涛 王可毅 贺未 白洁 《中国肺癌杂志》 CAS CSCD 北大核心 2015年第11期680-685,共6页
背景与目的肺小结节尤其是磨玻璃结节(ground glass opacity,GGO)病灶的定位是微创手术切除的难点,报道的方法很多但均有不足。本研究旨在探讨计算机断层扫描(computed tomography,CT)引导下Hook-wire术前定位在胸腔镜下(video-assisted... 背景与目的肺小结节尤其是磨玻璃结节(ground glass opacity,GGO)病灶的定位是微创手术切除的难点,报道的方法很多但均有不足。本研究旨在探讨计算机断层扫描(computed tomography,CT)引导下Hook-wire术前定位在胸腔镜下(video-assisted thoracoscopic surgery,VATS)肺结节切除术中的临床应用价值,并初步探讨GGOs积极微创手术治疗的必要性和可行性。方法 2013年5月-2015年6月共25例患者的26枚肺结节于术前行CT引导下Hookwire定位,然后施行胸腔镜楔形切除术。统计Hook-wire定位时间、成功率、并发症及楔形切除时间、住院时间等,计算病灶组织学分型中的恶性几率,讨论肺部GGOs积极手术治疗的必要性。结果共25例患者26个结节(男性10例,女性15例,6个实性结节,20个GGOs),病灶直径5 mm-20 mm(平均8 mm),病灶距离胸膜垂直距离5 mm-30mm(平均14 mm),CT引导下Hook-wire定位成功率为100%。VATS楔形切除术成功率为100%。CT定位时间平均10min(5 min-15 min),微创切除病灶所需时间平均20 min(15 min-40 min),平均住院时间为4 d(3 d-6 d)。4例患者定位后发生微量气胸,但无需闭式引流处理。术中定位针脱落1例,但仍于胸腔镜下观察到穿刺点脏层胸膜下血肿后,准确定位并成功切除。20个GGOs术后组织学诊断结果为:16个混合性GGOs(mixed GGO,m GGO)中,微浸润腺癌2例,腺癌5例,小细胞肺癌(small cell lung cancer,SCLC)1例,炎性病灶8例;4个纯GGOs(pure GGO,p GGO)中原位腺癌1例,非典型性腺瘤样增生(atypical adenomatoid hyperplasia,AAH)1例,炎性病灶2例。结论 CT引导下Hook-wire肺结节尤其是GGOs术前定位准确率高,相关并发症轻微,是一种安全、有效的方法,能快速确定下一步诊疗方案,值得临床推广;肺部m GGOs是恶性病灶的几率很大,积极微创手术治疗是非常必要的。 展开更多
关键词 肺磨玻璃样结节 电视胸腔镜手术 CT引导下Hook-wire定位
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CT引导下Hook-wire定位肺磨玻璃样微小结节微创切除的临床研究 被引量:18
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作者 初向阳 侯晓彬 +6 位作者 张连斌 薛志强 任志鹏 温佳新 刘毅 马克峰 孙玉鹗 《中国肺癌杂志》 CAS 北大核心 2014年第12期845-849,共5页
背景与目的肺磨玻璃样微小结节(ground glass opacity,GGO)病灶的定位是微创手术切除的技术难点。各种定位方法均有报道,但每一种方法均有其不足。本研究拟通过评价术中CT引导下Hook-wire定位对GGO微创切除的价值,初步探索肺部<10 mm... 背景与目的肺磨玻璃样微小结节(ground glass opacity,GGO)病灶的定位是微创手术切除的技术难点。各种定位方法均有报道,但每一种方法均有其不足。本研究拟通过评价术中CT引导下Hook-wire定位对GGO微创切除的价值,初步探索肺部<10 mm的GGO积极手术治疗的必要性和可行性。方法 2009年10月-2013年10月共32例GGO患者,41个GGO,行胸腔镜微创切除术,麻醉插管后皆在手术体位下行计算机断层扫描(computed tomography,CT)CT引导Hook-wire定位。记录术中CT引导下Hook-wire定位技术的失败率、并发症、胸腔镜手术转为开胸手术的几率、住院时间等,计算病灶组织学分型中的恶性几率,讨论肺部<10 mm的GGO积极手术治疗的必要性。结果共32例患者(男性15例,女性17例)行41个GGO胸腔镜微创切除术,其中2个病灶、3个病灶和5个病灶同时微创切除患者数量分别是3例、1例、1例。病灶直径2 mm-10 mm(平均5 mm),病灶距离胸膜垂直距离5 mm-24 mm(平均12.5 mm)。术中CT引导下Hook-wire定位成功率100%,严重并发症发生率0,转化为开胸手术比率为0,CT定位时间平均8.4 min(4 min-18 min),微创切除病灶所需时间平均32 min(14 min-98 min),中位住院时间为8 d(5 d-14 d)。GGOs术后组织学诊断结果为:原位腺癌(肺泡癌)19例,约46.3%,腺癌8例,约19.5%,大细胞癌1例,约2.4%,不典型腺瘤样增生9例,约22%,炎性病灶4例,约9.8%。结论肺部GGO是恶性病灶的几率很大,对典型GGO患者积极微创手术治疗是非常必要的;术中CT引导下Hook-wire定位技术极大提高GGO微创切除可行性、并发症发生率低,对于GGO的鉴别诊断及治疗具有很好的临床价值。 展开更多
关键词 肺磨玻璃样结节 CT引导下Hook-wire定位 微创切除
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肺小结节胸腔镜切除术前CT引导下双钩hook-wire定位的应用价值 被引量:25
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作者 黄小燕 郑屹峰 +2 位作者 潘锋 沈琦斌 邵国良 《介入放射学杂志》 CSCD 北大核心 2017年第12期1098-1101,共4页
目的探讨肺小结节胸腔镜术前CT引导下双钩hook-wire定位的应用价值。方法 54例患者共67个肺小结节病灶和63例患者共81个肺小结节病灶分别在胸腔镜切除术前行CT引导下双钩和单钩hook-wire定位,评价胸腔镜术前CT引导下双钩和单钩hook-wir... 目的探讨肺小结节胸腔镜术前CT引导下双钩hook-wire定位的应用价值。方法 54例患者共67个肺小结节病灶和63例患者共81个肺小结节病灶分别在胸腔镜切除术前行CT引导下双钩和单钩hook-wire定位,评价胸腔镜术前CT引导下双钩和单钩hook-wire定位技术的成功率、并发症发生率。结果 54例患者胸腔镜术前CT引导下肺小结节双钩hook-wire定位成功率100%,并发症有:气胸发生率29.6%(16/54)、出血发生率48.1%(26/54);63例患者胸腔镜术前CT引导下肺小结节单钩hookwire定位成功率98.4%(62/63),并发症有:气胸发生率28.5%(18/63)、出血发生率25.4%(16/63)。结论胸腔镜术前肺小结节CT引导下双钩hook-wire定位能够降低定位脱钩风险,是对其他肺小结节定位技术的重要补充。 展开更多
关键词 肺小结节 电子胸腔镜切除术 CT引导下定位 双钩钢丝
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CT引导下Hookwire定位孤立性肺结节的临床应用及并发症分析 被引量:20
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作者 张旭刚 杨磊 +4 位作者 魏博 姜福胜 李运 姜冠潮 王俊 《临床肺科杂志》 2017年第4期589-592,597,共5页
目的探讨CT引导下Hookwire定位孤立性肺结节(solitary pulmonary nodules SPNs)行电视胸腔镜手术(video-assisted thoracoscopic surgery,VATS)的临床价值及并发症发生的高危因素。方法回顾性分析84例患者88枚直径≤2cm的SPNs,在CT引导... 目的探讨CT引导下Hookwire定位孤立性肺结节(solitary pulmonary nodules SPNs)行电视胸腔镜手术(video-assisted thoracoscopic surgery,VATS)的临床价值及并发症发生的高危因素。方法回顾性分析84例患者88枚直径≤2cm的SPNs,在CT引导下Hookwire定位并VATS切除的临床资料,统计分析定位成功率、并发症、病理结果及定位操作相关数据等,对影响并发症的因素采用单因素分析及Logistic回归分析。结果共84例患者88枚SPNs(男性36例,女性48例),定位时间平均14.8±3.6min(8-38min);19例患者出现穿刺相关并发症,包括7例微量气胸,5例肺周血肿,4例合并出现微量气胸及肺周血肿,3例脱钩,全组无咯血、空气栓塞及血胸发生,并发症发生率22.6%(19/84);手术时间平均22.2±4.3min(15-50min),术中出血量平均20.3±3.7ml(10-50ml);3例脱钩者均在术中找到脏层胸膜穿刺出血点后成功切除病灶,全组无中转开胸,其中单纯楔形切除57例,楔形+肺叶切除27例;术后病理良性病灶30枚,癌前病变8枚,恶性病灶50枚;单因素分析显示肺部疾病史、结节与胸膜的距离、穿刺时间、进针角度及进针深度对并发症发生有显著影响(P<0.05);多因素Logistic回归分析提示肺部疾病史(OR=11.744;p=0.002)、穿刺时间(OR=8.472;P=0.006)、进针深度(OR=15.695;P=0.006)是并发症发生的独立危险因素。结论术前CT引导下Hookwire定位并VATS切除术是一种安全、高效的诊断及治疗SPNs方法;肺部疾病史、穿刺时间、进针深度是并发症发生的独立危险因素。 展开更多
关键词 电视胸腔镜手术 CT引导下Hook-wire定位 孤立性肺结节 并发症
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胸腔镜术前低剂量CT引导下Hook-wire联合亚甲蓝定位肺局灶性磨玻璃样病变 被引量:9
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作者 王玉涛 赵晓东 +7 位作者 朱勇刚 周成伟 卢斌 周银杰 葛明亮 张霞萍 邓生德 王海涛 《中国微创外科杂志》 CSCD 2012年第11期973-975,共3页
目的探讨低剂量CT(low-dose CT,LDCT)引导下Hook-wire联合亚甲蓝定位在胸腔镜下肺局灶性磨玻璃样病变(focal ground-glass opacity,fGGO)切除术中的临床应用价值。方法 2010年11月~2012年4月对21例单侧fGGO(直径5~17 mm,平均11.5 mm,... 目的探讨低剂量CT(low-dose CT,LDCT)引导下Hook-wire联合亚甲蓝定位在胸腔镜下肺局灶性磨玻璃样病变(focal ground-glass opacity,fGGO)切除术中的临床应用价值。方法 2010年11月~2012年4月对21例单侧fGGO(直径5~17 mm,平均11.5 mm,距壁层胸膜0~28 mm)行胸腔镜肺楔形切除术,术前皆行LDCT引导下Hook-wire定位,并辅以亚甲蓝染色。结果 LDCT引导下Hook-wire联合亚甲蓝定位成功率为100%,定位时间15~28 min,平均21 min。1例术中金属钩脱落,胸腔镜下观察肺组织表面血肿和亚甲蓝染色而成功手术切除;1例亚甲蓝染色失败,但Hook-wire锚定病灶亦成功手术切除。6例(28.6%)发生并发症,其中无症状气胸4例,无症状左上叶出血1例,无症状气胸和右下叶出血1例。VATS手术时间15~43 min,平均22 min;术中出血量23~38 ml,平均31 ml。术后住院5~12 d,平均7 d。fGGO术后病理:原位癌4例,微浸润腺癌3例,肺腺癌1例,不典型腺瘤样增生5例,错构瘤1例,间质性肺炎3例,肺内淋巴结增生2例,炎性肉芽肿2例。结论 LDCT引导下Hook-wire联合亚甲蓝定位fGGO的准确率高,并发症轻微。 展开更多
关键词 局灶性磨玻璃样病变 低剂量CT引导 HOOK-wire 亚甲蓝 电视胸腔镜手术
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CT引导下Hook-wire定位对早期肺癌术后复发率的影响 被引量:8
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作者 陈若 毛文君 +5 位作者 郑明峰 陈静瑜 何毅军 叶书高 刘峰 陆荣国 《临床肺科杂志》 2017年第2期211-216,共6页
目的探讨胸腔镜术前CT引导下Hook-wire不同定位方式,对Ⅰ期肺癌切除术后复发率的影响。方法 2010年1月至2013年12月,我院共收治了147例肺部孤立性小结节(solitary pulmonary nodule,SPN)或磨玻璃样病变(ground-glass opacity,GGO)。经... 目的探讨胸腔镜术前CT引导下Hook-wire不同定位方式,对Ⅰ期肺癌切除术后复发率的影响。方法 2010年1月至2013年12月,我院共收治了147例肺部孤立性小结节(solitary pulmonary nodule,SPN)或磨玻璃样病变(ground-glass opacity,GGO)。经过删选后共有125例患者纳入研究,其中SPN 81例,GGO 44例,所有患者胸腔镜手术前均行Hook-wire定位,68例患者接受Hook-wire穿刺针穿过病灶,57例贴近病灶定位于周围正常肺组织中。根据手术结果,评价Hook-wire不同定位方式定位的效果,对早期肺癌术后复发的影响,使用Logistic回归分析早期肺癌经Hook-wire定位切除术后复发的危险因素。结果 125例患者术前平均定位时间为(20±8)min,3例出现导丝脱落(2.4%),无症状并发症78例。所有患者均行胸腔镜下手术治疗,12例由于胸腔粘连中转开胸,术后病理:原发性肺癌76例,良性病变44例,5例为转移性肿瘤。原发性肺癌患者中,Hook-wire定位穿过病灶40例,贴近病灶定位36例,术后9例复发,前者复发率明显高于后者(20%vs 2.8%,P=0.031)。单因素和多因素Logistic回归分析显示,亚肺叶切除、病理为腺癌、Hook-wire穿过病灶定位、术前穿刺出血是术后复发的独立危险因素,术后辅助化疗为保护性因素。结论胸腔镜术前早期肺癌经CT引导下Hook-wire定位,穿过病灶定位的术后复发率高于贴近病灶定位,对于直径≤2.0 cm的早期肺癌,选择亚肺叶切除术需谨慎。 展开更多
关键词 CT引导 Hook—wire定位 早期肺癌 复发率 胸腔镜手术
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一种新型Visionwire标测导丝在心脏再同步化治疗中的应用 被引量:4
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作者 于海波 梁延春 +6 位作者 王祖禄 孙毅 许国卿 金志清 李世倍 付柳静 韩雅玲 《中国心脏起搏与心电生理杂志》 2012年第3期201-204,共4页
目的探讨一种新型Visionwire标测导丝在心脏再同步化治疗(CRT)左室电极植入过程中的应用价值。方法 5例因心力衰竭接受CRT的患者,分别采用Visionwire导丝及左室电极到达可植入左室电极的冠状静脉(CS)分支内进行起搏参数测试及电生理标测... 目的探讨一种新型Visionwire标测导丝在心脏再同步化治疗(CRT)左室电极植入过程中的应用价值。方法 5例因心力衰竭接受CRT的患者,分别采用Visionwire导丝及左室电极到达可植入左室电极的冠状静脉(CS)分支内进行起搏参数测试及电生理标测,比较两种方法的起搏参数测试、电生理标测结果及手术时间。结果在5例患者的16个CS分支中,两种方法所测的起搏参数值无显著性差异,二者的起搏阈值有强相关性(r=0.90,P<0.01),感知亦有相关性(r=0.67,P<0.01),二者最大起搏电压引起膈肌刺激的部位相似。应用Visionwire导丝可以进行局部电位电激动顺序标测。Visionwire导丝对单个CS分支进行起搏参数测定比应用左室电极进行起搏参数测定所需时间明显缩短(12.4±7.5 min vs 18.3±12.2 min,P<0.01)。结论应用Visionwire标测导丝可以预测CS分支的左室电极起搏参数,根据局部电位延迟可准确定位左室电极植入部位。 展开更多
关键词 心血管病学 心脏再同步化治疗 Visionwire导丝 左室电极 起搏参数
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