Gunshot Residue(GSR)has been a subject of interest for the forensic fraternity.Numerous analytical contributions towards the GSR analysis have been reported.Sensitivity,portability,cost-effectiveness,speed,etc.are suc...Gunshot Residue(GSR)has been a subject of interest for the forensic fraternity.Numerous analytical contributions towards the GSR analysis have been reported.Sensitivity,portability,cost-effectiveness,speed,etc.are such factors of electrochemical methods that have attracted the researchers across the globe to test the applicability of these as a potential analytical tool for forensic evaluation of GSR.With the development of scientific technology,efforts have been made towards the handheld device for the on-field analysis of GSR.Recently,chemometric treatment of data generated from the electrochemical analysis of GSR has offered more effective approach.It makes the analysis more conclusive and minimizes the chances of false-positive detection.It will be very fruitful to anticipate the analytical potential of electrochemical tools for GSR analysis.This article reviews the research progress towards the development of electrochemical sensor for GSR detection reported during 2013-2020 along with challenges and future perspectives.展开更多
A high performance liquid chromatography tandem mass spectrometry/mass spectrometry(HPLC-MS/MS)protocol was developed for the determination of diphenylamine(DPA).Four productions of DPA were selected for qualitative a...A high performance liquid chromatography tandem mass spectrometry/mass spectrometry(HPLC-MS/MS)protocol was developed for the determination of diphenylamine(DPA).Four productions of DPA were selected for qualitative assay and the peak area of the main product ion for quantitation.By means of separation using an Agilent Extend-C18 column(CA,USA)(150 mm×4.6 mm,5μm)with methanol‑water(90:10)as the mobile phase,DPA was detected by electrospray ionization(ESI)tandem mass spectrometry in positive mode.The linearity of the peak area versus concentration ranged 5‑500 ng/mL,r^(2)=0.9978.The limit of detection(S/N=3)of this method was 0.3 ng/mL.This method is applicable for the determination of DPA in gunshot residue.展开更多
基金the University Grants Commission(UGC),Ministry of EducationGovernment of India,for providing financial assistance(UGC-JRF vide Letter No.190521040928)to the first author(AH).
文摘Gunshot Residue(GSR)has been a subject of interest for the forensic fraternity.Numerous analytical contributions towards the GSR analysis have been reported.Sensitivity,portability,cost-effectiveness,speed,etc.are such factors of electrochemical methods that have attracted the researchers across the globe to test the applicability of these as a potential analytical tool for forensic evaluation of GSR.With the development of scientific technology,efforts have been made towards the handheld device for the on-field analysis of GSR.Recently,chemometric treatment of data generated from the electrochemical analysis of GSR has offered more effective approach.It makes the analysis more conclusive and minimizes the chances of false-positive detection.It will be very fruitful to anticipate the analytical potential of electrochemical tools for GSR analysis.This article reviews the research progress towards the development of electrochemical sensor for GSR detection reported during 2013-2020 along with challenges and future perspectives.
基金This study was supported by the Basal Research Fund Program of Institute of Forensic Science,Ministry of Public Security,China(2014JB006).
文摘A high performance liquid chromatography tandem mass spectrometry/mass spectrometry(HPLC-MS/MS)protocol was developed for the determination of diphenylamine(DPA).Four productions of DPA were selected for qualitative assay and the peak area of the main product ion for quantitation.By means of separation using an Agilent Extend-C18 column(CA,USA)(150 mm×4.6 mm,5μm)with methanol‑water(90:10)as the mobile phase,DPA was detected by electrospray ionization(ESI)tandem mass spectrometry in positive mode.The linearity of the peak area versus concentration ranged 5‑500 ng/mL,r^(2)=0.9978.The limit of detection(S/N=3)of this method was 0.3 ng/mL.This method is applicable for the determination of DPA in gunshot residue.
