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Quality of Life in Chronic Kidney Disease Patients on Dialysis at the University Teaching Hospital-Adult Hospital, Lusaka, Zambia
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作者 Justina Kasonde Majorie Makukula Emmanuel Musenge 《Open Journal of Nephrology》 CAS 2022年第4期460-481,共22页
Introduction: The importance of determining health related quality of life in Chronic Kidney Disease patients on dialysis is well established. However, research was limited in establishing the health related quality o... Introduction: The importance of determining health related quality of life in Chronic Kidney Disease patients on dialysis is well established. However, research was limited in establishing the health related quality of life for chronic kidney disease patients on dialysis at University Teaching Hospital-Adult Hospital. Further the effects of haemoglobin levels and adequacy of dialysis on their health related quality of life were unknown. Therefore, the study sought to answer a research question: what is the health-related Quality of Life for Chronic Kidney Disease patients on dialysis at University Teaching Hospital? Method: The study was an analytical cross-sectional study that used a census sampling method. The study participants comprised of 104 patients who sought dialysis services (2020-2021) from the University Teaching Hospital-Renal Unit in Lusaka, Zambia. A structured Kidney Disease Quality of Life Short form (KDQOL-SF 36) was used to collect data. The Data was analyzed using the Statistics and Data software version 13, Chi-square tests, and logistic regression analysis was employed to analyse the data. A confidence interval of 95% was set with a significant level of 0.05. Results: The study included 104 Chronic Kidney Disease patients from the Dialysis Unit at University Teaching Hospital in Lusaka, Zambia. Two-thirds (68%) of the patients had a good overall health-related quality of life with the biological wellbeing having exceptionally high scores. The male gender (66.7%), unemployment (69.4%), and low haemoglobin levels (77.8%) were identified as factors associated with poor health-related quality of life. Conclusion: The health related quality of life of Chronic Kidney Disease patients at University Teaching Hospital was good. Low haemoglobin levels, age, male sex and unemployment were found to be factors associated with poor health related quality of life. Integration of health-related quality of life assessment for Chronic Kidney disease patients on dialysis in routine care is paramount. Particular focus should be on patients presenting with low haemoglobin levels, age, male sex and unemployment for timely interventions. 展开更多
关键词 Health-Related Quality of Life DIALYSIS Chronic Kidney Disease Ade-quacy of Dialysis haemoglobin levels
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限制性输血对直肠癌保肛术后并发症影响分析 被引量:4
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作者 赵家运 王志刚 潘乐玉 《临床外科杂志》 2018年第10期763-766,共4页
目的探讨限制性输血和开放性输血对直肠癌保肛术后吻合口漏和感染性并发症的影响。方法行保肛手术的直肠癌病人289例。根据围手术期最低血红蛋白水平和输血状态分为4组。组1:血红蛋白≥100 g/L,未输血;组2:血红蛋白≥70 g/L但<100 g... 目的探讨限制性输血和开放性输血对直肠癌保肛术后吻合口漏和感染性并发症的影响。方法行保肛手术的直肠癌病人289例。根据围手术期最低血红蛋白水平和输血状态分为4组。组1:血红蛋白≥100 g/L,未输血;组2:血红蛋白≥70 g/L但<100 g/L,未输血;组3:血红蛋白≥70 g/L但<100 g/L,输血;组4:血红蛋白<70 g/L,输血。对4组病人的临床基本资料、术后30天内吻合口漏和感染并发症进行比较。结果 289例直肠癌病人平均年龄为(58. 2±10. 8)岁。组1、组2、组3、组4分别为121例、115例、32例、21例。4组间术前新辅助化疗、白蛋白水平、术中出血量、肿瘤大小以及TNM分期等指标有明显差异。4组病人总体感染性并发症发生率分别为16. 5%、28. 7%、40. 6%和52. 4%。结论对围手术期血红蛋白水平≥70 g/L的直肠癌病人进行输血治疗会增加术后手术部位感染、总体感染性并发症及术后吻合口漏的发生率。 展开更多
关键词 直肠癌 血红蛋白 限制性输血 开放性输血 并发症
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全自动血沉仪TEST 1与魏氏法血沉结果对比及临床应用价值分析 被引量:1
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作者 王亚东 《中国继续医学教育》 2020年第23期99-102,共4页
目的比较全自动红细胞沉降率仪TEST 1与魏氏法血沉结果,并探讨全自动红细胞沉降率仪TEST 1的临床应用价值。方法根据血红蛋白浓度的不同,对临床436例标本的血沉值进行配对设计的t检验,相关分析及回归分析;连续监测4例患者的血沉及其它指... 目的比较全自动红细胞沉降率仪TEST 1与魏氏法血沉结果,并探讨全自动红细胞沉降率仪TEST 1的临床应用价值。方法根据血红蛋白浓度的不同,对临床436例标本的血沉值进行配对设计的t检验,相关分析及回归分析;连续监测4例患者的血沉及其它指标,探讨全自动红细胞沉降率仪TEST1检测的血沉与病情变化的关系。结果血红蛋白浓度(Hb)<=120 g/L时,全自动红细胞沉降率仪TEST 1与魏氏法之间结果比较差异具有统计学意义;血红蛋白浓度(Hb)>=121 g/L时,全自动红细胞沉降率仪TEST 1与魏氏法检测之间结果比较差异无统计学意义;全自动红细胞沉降率仪TEST 1检测的血沉与病情的变化同步。结论在监测疾病的发展变化中,全自动红细胞沉降率仪TEST l比魏氏法更及时反应病情变化,且具有简单﹑快速﹑准确的优势。 展开更多
关键词 血沉 全自动红细胞沉降率仪TEST 1 魏氏法血沉 国际血液学标准化委员会 血红蛋白浓度 回归分析
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孕早期血红蛋白水平与妊娠期糖尿病的关系研究:基于出生人口队列 被引量:7
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作者 闫明鑫 赵豆豆 +5 位作者 宛惠玲 赵欢 单莉 裴磊磊 米阳 屈鹏飞 《中华疾病控制杂志》 CAS CSCD 北大核心 2023年第1期60-64,76,共6页
目的探究中国西北地区孕妇孕早期血红蛋白水平与妊娠期糖尿病(gestational diabetes mellitus,GDM)的关系。方法连续纳入2018年7月―2019年7月加入西北妇女儿童医院出生人口队列的孕早期孕妇,调查其基本人口学特征、生活行为方式等资料... 目的探究中国西北地区孕妇孕早期血红蛋白水平与妊娠期糖尿病(gestational diabetes mellitus,GDM)的关系。方法连续纳入2018年7月―2019年7月加入西北妇女儿童医院出生人口队列的孕早期孕妇,调查其基本人口学特征、生活行为方式等资料,并对研究对象的孕早期血红蛋白水平、口服葡萄糖耐量试验(oral glucose tolerance test,OGTT)结果进行随访。首先使用logistic回归分析模型分析孕早期血红蛋白水平对GDM的影响,进一步采用限制性三次立方样条来呈现血红蛋白水平与GDM的非线性关系。结果在调整了混杂因素后,孕早期高血红蛋白水平(血红蛋白≥135 g/L)增加了GDM的发生风险(OR=1.44,95%CI:1.13~1.83);孕早期血红蛋白水平每升高10 g/L,FPG、OGTT 1h血糖、OGTT 2h血糖水平分别升高0.03 mmol/L(95%CI:0.01~0.05)、0.14 mmol/L(95%CI:0.07~0.21)、0.13 mmol/L(95%CI:0.08~0.19);限制性立方样条结果显示,随着孕早期血红蛋白水平升高,GDM的发生风险逐渐升高。结论孕早期血红蛋白水平升高将增加GDM的发病风险,应积极对孕妇孕早期血红蛋白水平进行监测,促进母婴健康。 展开更多
关键词 妊娠期糖尿病 孕早期 血红蛋白水平 口服葡萄糖耐量试验
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