Mycoplasma hominis is an opportunistic microorganism that colonizes the genitourinary tract and causes genitourinary infections.However,pulmonary infections caused by M.hominis have rarely been reported in immunocompe...Mycoplasma hominis is an opportunistic microorganism that colonizes the genitourinary tract and causes genitourinary infections.However,pulmonary infections caused by M.hominis have rarely been reported in immunocompetent individuals.Herein,we report a rare case of an immunocompetent adult male with M.hominis pneumonia who presented with multiple pulmonary nodules that progressed to a cavitary mass with a halo sign.The presence of M.hominis infection was confirmed using multiplex polymerase chain reaction(mPCR)of the bronchoalveolar lavage fluid.The patient demonstrated no response to the initial levofloxacin therapy;however,the symptoms subsequently improved after the administration of moxifloxacin.M.hominis may be an underestimated causative agent of community-acquired pneumonia of unknown etiology in immunocompetent adults,and the involvement of the organism should be especially suspected in sexually active patients.Molecular diagnostic methods,such as mPCR,can be used to identify the etiology of atypical pneumonia.Appropriate antibiotics are crucial for effective treatment.展开更多
Primary epithelioid hemangioendotheliomas of the liver(EHL)are rare tumors with a low incidence.The molecular background of EHL is still under investigation,with WWTR1-CAMPTA1 mutation may function as a tumor marker.C...Primary epithelioid hemangioendotheliomas of the liver(EHL)are rare tumors with a low incidence.The molecular background of EHL is still under investigation,with WWTR1-CAMPTA1 mutation may function as a tumor marker.Commonly,this tumor is misdiagnosed with angiosarcoma,cholangiocarcinomas,metastatic carcinoma,and hepatocellular carcinoma(sclerosing variant).Characteristic features on imaging modalities such as ultrasound,computed tomography,magnetic resonance imaging and positron emission tomography/computed tomography guide in diagnosis and staging.The“halo sign”and the“lollipop sign”on computed tomography and magnetic resonance imaging are described in the literature.Currently,there are no standardized guidelines for treating EHL with treatment options are broad including:chemotherapy,ablation,surgery and liver transplantation with inconsistent results.展开更多
基金supported by the Top-Notch Project for Youth Training(20QNPY115).
文摘Mycoplasma hominis is an opportunistic microorganism that colonizes the genitourinary tract and causes genitourinary infections.However,pulmonary infections caused by M.hominis have rarely been reported in immunocompetent individuals.Herein,we report a rare case of an immunocompetent adult male with M.hominis pneumonia who presented with multiple pulmonary nodules that progressed to a cavitary mass with a halo sign.The presence of M.hominis infection was confirmed using multiplex polymerase chain reaction(mPCR)of the bronchoalveolar lavage fluid.The patient demonstrated no response to the initial levofloxacin therapy;however,the symptoms subsequently improved after the administration of moxifloxacin.M.hominis may be an underestimated causative agent of community-acquired pneumonia of unknown etiology in immunocompetent adults,and the involvement of the organism should be especially suspected in sexually active patients.Molecular diagnostic methods,such as mPCR,can be used to identify the etiology of atypical pneumonia.Appropriate antibiotics are crucial for effective treatment.
文摘Primary epithelioid hemangioendotheliomas of the liver(EHL)are rare tumors with a low incidence.The molecular background of EHL is still under investigation,with WWTR1-CAMPTA1 mutation may function as a tumor marker.Commonly,this tumor is misdiagnosed with angiosarcoma,cholangiocarcinomas,metastatic carcinoma,and hepatocellular carcinoma(sclerosing variant).Characteristic features on imaging modalities such as ultrasound,computed tomography,magnetic resonance imaging and positron emission tomography/computed tomography guide in diagnosis and staging.The“halo sign”and the“lollipop sign”on computed tomography and magnetic resonance imaging are described in the literature.Currently,there are no standardized guidelines for treating EHL with treatment options are broad including:chemotherapy,ablation,surgery and liver transplantation with inconsistent results.
