Parkinson’s disease (PD) is a neurodegenerative disease that occurs due to loss of nerve cells that produce dopamine in the brain, affecting approximately 4 million people worldwide. PD patients often feel an increas...Parkinson’s disease (PD) is a neurodegenerative disease that occurs due to loss of nerve cells that produce dopamine in the brain, affecting approximately 4 million people worldwide. PD patients often feel an increase in anxiety levels daily. While there are medications/exercises to help relieve anxiety, there are limited methods to reduce anxiety without the help of a caretaker. As a result, MEDIC Foundation, a non-profit organization in British Columbia, Canada, is designing an automated system that consists of a wristband and an application which uses vi-bration therapy to help reduce anxiety of PD patients. Literature reviews were conducted to document the project’s needs. Phase I of the project focused on de-veloping a prototype for the application and phase II on developing the wrist-band. The team developed prototypes of a wristband that automatically applies vibration near the median nerve as the heart rate variability (HRV) deviates away from the normal threshold of the user, and an application that displays real-time heart rate variability signals as well as provides for relaxation. The development of the prototype is still in early progress. By creating this automated system, we aim to provide a solution to senior PD patients to relieve anxiety independently. .展开更多
This paper deals about a quantitative and qualitative study of the sustained vibration pat-terns of vocal cords with a mulfifunctional glottograph developed by the authors.The glottogramsand their parameters for the m...This paper deals about a quantitative and qualitative study of the sustained vibration pat-terns of vocal cords with a mulfifunctional glottograph developed by the authors.The glottogramsand their parameters for the modal,falsetto,breathy and pressed voices are presented.This paper al-so sets out to explore the influence of the changes in the properties of the vocal tract andfundamental frequency,on vocal cord vibration.Typical clinical results show that the glottographicmethod may be used in the diagnosis and treatment of laryngeal diseases,phonation physiology andevaluation of artistic voice.展开更多
Field an experiment was carried out in the farms of Agriculture and forestry academy at University in Nineveh. The research was conducted to investigate a practical study for the effect of four forward speeds (1.9, 2....Field an experiment was carried out in the farms of Agriculture and forestry academy at University in Nineveh. The research was conducted to investigate a practical study for the effect of four forward speeds (1.9, 2.6, 3.8 and 4.7 km/hr.) and three acceleration direction of axes lateral, longitudinal and vertical, and two types machines control (Mower and Rotovators) on the vibrations transferred to the steering wheel horticulture tractor type (Goldoni). The vibration points on the handgrip were calculated and tested. Root mean square acceleration (RMS), given in m/sec2, was calculated. Results showed increased acceleration vibration of the three directions (longitudinal, lateral and vertical) transferred to the steering wheel tractor by increased forward speed. The Mower score recorded the highest acceleration vibration for the three directions of Rotovators. The levels of vibration emitted from tractor to hand an operator during the experiment was high comparing with standard mechanical vibration. Handgrip vibration intensity in the vertical direction is bigger than the lateral and longitudinal direction. The total vibration evaluating was denoted as the square root mean of the three sum value (lateral, longitudinal and vertical) directions. The paper purpose was measuring and analyzing vibration level transferred to the steering wheel and reduces the machine vibration. This paper is helpful for design in order to increase the develop safety systems in easy and economical way.展开更多
BACKGROUND Vibration-controlled transient elastography(VCTE)is proposed as a second step of examination to assess liver fibrosis in patients with nonalcoholic fatty liver disease(NAFLD)after triaging by the fibrosis-4...BACKGROUND Vibration-controlled transient elastography(VCTE)is proposed as a second step of examination to assess liver fibrosis in patients with nonalcoholic fatty liver disease(NAFLD)after triaging by the fibrosis-4(FIB-4)index.Recently,VCTEbased scoring systems,including FibroScan-AST(FAST),Agile 3+,and Agile 4,emerged to determine the status of NAFLD.However,the significance of these scoring systems remains unknown in narrowing the high-risk group of NAFLD patients with comorbidities,including hepatocellular carcinoma(HCC)and esophagogastric varices(EGV).AIM To clarify the significance of VCTE-based scoring systems to narrow the high-risk group of NAFLD patients with comorbidities.METHODS We performed a cross-sectional study to investigate the usefulness of VCTE-based scoring systems and other fibrosis markers to narrow the high-risk group of patients with NAFLD.FIB-4 index was used for the first triage.Risk groups of FAST,Agile 3+,and Agile 4 were stratified according to the published data.Among the 191 patients with NAFLD,there were 26(14%)and 25 patients(13%)with HCC and EGV,respectively.RESULTS When 1.3 was used as a cutoff value,the FIB-4 index narrowed the risk group to 120 patients,in which all patients with HCC and/or EGV were included.High risk group of Agile 3+could subsequently narrow the risk group.The prevalence of HCC and EGV at this step were 33%(26/80)and 31%(25/80),respectively.In further narrowing of EGV,Agile 4 aggregated the patients with EGV into 43 patients,of whom 23(53%)had EGV.FAST failed to narrow the risk group of patients with comorbidities.When 2.6 was used as a cutoff value of the FIB-4 index,three patients with HCC and two patients with EGV were missed at the first triage.CONCLUSION Agile 3+and Agile 4 are useful to narrow the NAFLD patient group,in which patients may have HCC and/or EGV.展开更多
文摘Parkinson’s disease (PD) is a neurodegenerative disease that occurs due to loss of nerve cells that produce dopamine in the brain, affecting approximately 4 million people worldwide. PD patients often feel an increase in anxiety levels daily. While there are medications/exercises to help relieve anxiety, there are limited methods to reduce anxiety without the help of a caretaker. As a result, MEDIC Foundation, a non-profit organization in British Columbia, Canada, is designing an automated system that consists of a wristband and an application which uses vi-bration therapy to help reduce anxiety of PD patients. Literature reviews were conducted to document the project’s needs. Phase I of the project focused on de-veloping a prototype for the application and phase II on developing the wrist-band. The team developed prototypes of a wristband that automatically applies vibration near the median nerve as the heart rate variability (HRV) deviates away from the normal threshold of the user, and an application that displays real-time heart rate variability signals as well as provides for relaxation. The development of the prototype is still in early progress. By creating this automated system, we aim to provide a solution to senior PD patients to relieve anxiety independently. .
基金The project was supported by the National Natural Science Foundation of China No.6881030
文摘This paper deals about a quantitative and qualitative study of the sustained vibration pat-terns of vocal cords with a mulfifunctional glottograph developed by the authors.The glottogramsand their parameters for the modal,falsetto,breathy and pressed voices are presented.This paper al-so sets out to explore the influence of the changes in the properties of the vocal tract andfundamental frequency,on vocal cord vibration.Typical clinical results show that the glottographicmethod may be used in the diagnosis and treatment of laryngeal diseases,phonation physiology andevaluation of artistic voice.
文摘Field an experiment was carried out in the farms of Agriculture and forestry academy at University in Nineveh. The research was conducted to investigate a practical study for the effect of four forward speeds (1.9, 2.6, 3.8 and 4.7 km/hr.) and three acceleration direction of axes lateral, longitudinal and vertical, and two types machines control (Mower and Rotovators) on the vibrations transferred to the steering wheel horticulture tractor type (Goldoni). The vibration points on the handgrip were calculated and tested. Root mean square acceleration (RMS), given in m/sec2, was calculated. Results showed increased acceleration vibration of the three directions (longitudinal, lateral and vertical) transferred to the steering wheel tractor by increased forward speed. The Mower score recorded the highest acceleration vibration for the three directions of Rotovators. The levels of vibration emitted from tractor to hand an operator during the experiment was high comparing with standard mechanical vibration. Handgrip vibration intensity in the vertical direction is bigger than the lateral and longitudinal direction. The total vibration evaluating was denoted as the square root mean of the three sum value (lateral, longitudinal and vertical) directions. The paper purpose was measuring and analyzing vibration level transferred to the steering wheel and reduces the machine vibration. This paper is helpful for design in order to increase the develop safety systems in easy and economical way.
文摘BACKGROUND Vibration-controlled transient elastography(VCTE)is proposed as a second step of examination to assess liver fibrosis in patients with nonalcoholic fatty liver disease(NAFLD)after triaging by the fibrosis-4(FIB-4)index.Recently,VCTEbased scoring systems,including FibroScan-AST(FAST),Agile 3+,and Agile 4,emerged to determine the status of NAFLD.However,the significance of these scoring systems remains unknown in narrowing the high-risk group of NAFLD patients with comorbidities,including hepatocellular carcinoma(HCC)and esophagogastric varices(EGV).AIM To clarify the significance of VCTE-based scoring systems to narrow the high-risk group of NAFLD patients with comorbidities.METHODS We performed a cross-sectional study to investigate the usefulness of VCTE-based scoring systems and other fibrosis markers to narrow the high-risk group of patients with NAFLD.FIB-4 index was used for the first triage.Risk groups of FAST,Agile 3+,and Agile 4 were stratified according to the published data.Among the 191 patients with NAFLD,there were 26(14%)and 25 patients(13%)with HCC and EGV,respectively.RESULTS When 1.3 was used as a cutoff value,the FIB-4 index narrowed the risk group to 120 patients,in which all patients with HCC and/or EGV were included.High risk group of Agile 3+could subsequently narrow the risk group.The prevalence of HCC and EGV at this step were 33%(26/80)and 31%(25/80),respectively.In further narrowing of EGV,Agile 4 aggregated the patients with EGV into 43 patients,of whom 23(53%)had EGV.FAST failed to narrow the risk group of patients with comorbidities.When 2.6 was used as a cutoff value of the FIB-4 index,three patients with HCC and two patients with EGV were missed at the first triage.CONCLUSION Agile 3+and Agile 4 are useful to narrow the NAFLD patient group,in which patients may have HCC and/or EGV.
