BACKGROUND Cognitive frailty,characterized by the coexistence of cognitive impairment and physical frailty,represents a multifaceted challenge in the aging population.The role of cardiovascular risk factors in this co...BACKGROUND Cognitive frailty,characterized by the coexistence of cognitive impairment and physical frailty,represents a multifaceted challenge in the aging population.The role of cardiovascular risk factors in this complex interplay is not yet fully understood.AIM To investigate the relationships between cardiovascular risk factors and older persons with cognitive frailty by pooling data from two cohorts of studies in Malaysia.METHODS A comprehensive approach was employed,with a total of 512 communitydwelling older persons aged 60 years and above,involving two cohorts of older persons from previous studies.Datasets related to cardiovascular risks,namely sociodemographic factors,and cardiovascular risk factors,including hypertension,diabetes,hypercholesterolemia,anthropometric characteristics and biochemical profiles,were pooled for analysis.Cognitive frailty was defined based on the Clinical Dementia Rating scale and Fried frailty score.Cardiovascular risk was determined using Framingham risk score.Statistical analyses were conducted using SPSS version 21.RESULTS Of the study participants,46.3%exhibited cognitive frailty.Cardiovascular risk factors including hypertension(OR:1.60;95%CI:1.12-2.30),low fat-free mass(OR:0.96;95%CI:0.94-0.98),high percentage body fat(OR:1.04;95%CI:1.02-1.06),high waist circumference(OR:1.02;95%CI:1.01-1.04),high fasting blood glucose(OR:1.64;95%CI:1.11-2.43),high Framingham risk score(OR:1.65;95%CI:1.17-2.31),together with sociodemographic factors,i.e.,being single(OR 3.38;95%CI:2.26-5.05)and low household income(OR 2.18;95%CI:1.44-3.30)were found to be associated with cognitive frailty.CONCLUSION Cardiovascular-risk specific risk factors and sociodemographic factors were associated with risk of cognitive frailty,a prodromal stage of dementia.Early identification and management of cardiovascular risk factors,particularly among specific group of the population might mitigate the risk of cognitive frailty,hence preventing dementia.展开更多
[Objectives]To study the impact of basic demographic variables on the cognitive function of patients with depression,to further understand the personality characteristics of patients with depression with impaired cogn...[Objectives]To study the impact of basic demographic variables on the cognitive function of patients with depression,to further understand the personality characteristics of patients with depression with impaired cognitive function and the coping style of daily dealing with problems,and analyse the correlation among them.[Methods]The score of Self-Rating Depression Scale(SDS)was used as the inclusion criteria,with a total score of more than 60 indicating moderate depression and a total score of more than 130 as the criteria.Inclusion criteria were only met when the two criteria were met.Eysenck Personality Questionnaire(EPQ-RSC)and Simple Coping Style Questionnaire(SCSQ)were used to study the personality characteristics and coping styles of depressed patients with impaired cognitive function.A total of 113 people were surveyed,and 75 were finally included.SPSS software was used for analysis,independent sample t test was used for demographic variables,and one-way ANOVA was performed for multiple groups of levels.Pearson correlation analysis was used in the correlation study of personality characteristics,coping style and cognitive function of depression.Multiple regression analysis was used to predict the effects of personality traits and coping styles on cognitive impairment of depression.[Results]Factors influencing cognitive function include age,gender,place of origin,only-child or not,and education level.There was no significant statistical difference.Neuroticism was positively correlated with cognitive impairment in depression(γ=0.438,P<0.05);the extraverted dimension was negatively correlated with cognitive impairment of depression(γ=-0.335,P<0.05);Positive coping styles were negatively correlated with cognitive impairment in depression(γ=-0.415,P<0.05),negative coping style was positively correlated with cognitive impairment of depression(γ=0.299,P<0.05).[Conclusions]Demographic variables have little influence on the cognitive function of patients with depression.Personality characteristics and coping styles are closely correlated with the cognitive function of depression.Neuroticism,negative and positive ways have significant influence and predictive effect on the cognitive function of depression.展开更多
Objective:The aims of this study was to explore the clinical characteristics of patients with digestive tract cancer-related cognitive impairment(CRCI),and provide reference for the comprehensive clinical understandin...Objective:The aims of this study was to explore the clinical characteristics of patients with digestive tract cancer-related cognitive impairment(CRCI),and provide reference for the comprehensive clinical understanding,early prevention and treatment.Methods:164 patients with digestive tract cancer were divided into CRCI group and non-CRCI impairment group based on the Montreal Cognitive Assessment Scale(MOCA)and the Minimal Mental State Scale(MMSE).Baseline features,blood biochemical indexes,anxiety and depression were compared.Statistical analysis were carried out by SPSS software(version 20.0).Results:Among all the patients with CRCI,males were more common.Also,there were statistically differences in marital status,liver metastasis,hypertension,ferritin(FER),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C),NK cells,anxiety and depression(P<0.05).Conclusion:Part of patients with digestive tract cancer have varied degrees of cognitive dysfunction.Marital status,hypertension,immune function,liver metastasis and serum lipid metabolism were the risk factors for patients with digestive tract CRCI.Early identification of CRCI is of great significance to ensure the integrity of treatment,improve the quality of life and prognosis for patients with digestive tract CRCI.展开更多
This study examined the influence of Big Five personality traits on Facebook usage and examined the interactions of traits in this context based on Torgersen’s (1995) typological approach. The effect of self-esteem, ...This study examined the influence of Big Five personality traits on Facebook usage and examined the interactions of traits in this context based on Torgersen’s (1995) typological approach. The effect of self-esteem, narcissism, loneliness, shyness and boredom proneness on Facebook usage was also investigated. The sample included both student (N = 190) and (N = 184) non-student samples. Narcissism was the strongest predictor of time spent on Facebook per day for both students and non-students. Narcissism was also the strongest predictor of number of daily logins for non-students, however, agreeableness was the strongest predictor of logins for students. Extraversion was the strongest predictor of number of Facebook friends for both students and non- students, however the interaction of Extraversion and Neuroticism was also a predictor of Facebook friends for students, and the interaction of Extraversion and Conscientiousness for non-students. Future research should consider the combined effect of personality traits on overall Facebook use.展开更多
基金Supported by Long-term Research Grant Scheme provided by Ministry of Education Malaysia,No.LRGS/1/2019/UM-UKM/1/4Grand Challenge Grant Project 1 and Project 2,No.DCP-2017-002/1,No.DCP-2017-002/2.
文摘BACKGROUND Cognitive frailty,characterized by the coexistence of cognitive impairment and physical frailty,represents a multifaceted challenge in the aging population.The role of cardiovascular risk factors in this complex interplay is not yet fully understood.AIM To investigate the relationships between cardiovascular risk factors and older persons with cognitive frailty by pooling data from two cohorts of studies in Malaysia.METHODS A comprehensive approach was employed,with a total of 512 communitydwelling older persons aged 60 years and above,involving two cohorts of older persons from previous studies.Datasets related to cardiovascular risks,namely sociodemographic factors,and cardiovascular risk factors,including hypertension,diabetes,hypercholesterolemia,anthropometric characteristics and biochemical profiles,were pooled for analysis.Cognitive frailty was defined based on the Clinical Dementia Rating scale and Fried frailty score.Cardiovascular risk was determined using Framingham risk score.Statistical analyses were conducted using SPSS version 21.RESULTS Of the study participants,46.3%exhibited cognitive frailty.Cardiovascular risk factors including hypertension(OR:1.60;95%CI:1.12-2.30),low fat-free mass(OR:0.96;95%CI:0.94-0.98),high percentage body fat(OR:1.04;95%CI:1.02-1.06),high waist circumference(OR:1.02;95%CI:1.01-1.04),high fasting blood glucose(OR:1.64;95%CI:1.11-2.43),high Framingham risk score(OR:1.65;95%CI:1.17-2.31),together with sociodemographic factors,i.e.,being single(OR 3.38;95%CI:2.26-5.05)and low household income(OR 2.18;95%CI:1.44-3.30)were found to be associated with cognitive frailty.CONCLUSION Cardiovascular-risk specific risk factors and sociodemographic factors were associated with risk of cognitive frailty,a prodromal stage of dementia.Early identification and management of cardiovascular risk factors,particularly among specific group of the population might mitigate the risk of cognitive frailty,hence preventing dementia.
文摘[Objectives]To study the impact of basic demographic variables on the cognitive function of patients with depression,to further understand the personality characteristics of patients with depression with impaired cognitive function and the coping style of daily dealing with problems,and analyse the correlation among them.[Methods]The score of Self-Rating Depression Scale(SDS)was used as the inclusion criteria,with a total score of more than 60 indicating moderate depression and a total score of more than 130 as the criteria.Inclusion criteria were only met when the two criteria were met.Eysenck Personality Questionnaire(EPQ-RSC)and Simple Coping Style Questionnaire(SCSQ)were used to study the personality characteristics and coping styles of depressed patients with impaired cognitive function.A total of 113 people were surveyed,and 75 were finally included.SPSS software was used for analysis,independent sample t test was used for demographic variables,and one-way ANOVA was performed for multiple groups of levels.Pearson correlation analysis was used in the correlation study of personality characteristics,coping style and cognitive function of depression.Multiple regression analysis was used to predict the effects of personality traits and coping styles on cognitive impairment of depression.[Results]Factors influencing cognitive function include age,gender,place of origin,only-child or not,and education level.There was no significant statistical difference.Neuroticism was positively correlated with cognitive impairment in depression(γ=0.438,P<0.05);the extraverted dimension was negatively correlated with cognitive impairment of depression(γ=-0.335,P<0.05);Positive coping styles were negatively correlated with cognitive impairment in depression(γ=-0.415,P<0.05),negative coping style was positively correlated with cognitive impairment of depression(γ=0.299,P<0.05).[Conclusions]Demographic variables have little influence on the cognitive function of patients with depression.Personality characteristics and coping styles are closely correlated with the cognitive function of depression.Neuroticism,negative and positive ways have significant influence and predictive effect on the cognitive function of depression.
文摘Objective:The aims of this study was to explore the clinical characteristics of patients with digestive tract cancer-related cognitive impairment(CRCI),and provide reference for the comprehensive clinical understanding,early prevention and treatment.Methods:164 patients with digestive tract cancer were divided into CRCI group and non-CRCI impairment group based on the Montreal Cognitive Assessment Scale(MOCA)and the Minimal Mental State Scale(MMSE).Baseline features,blood biochemical indexes,anxiety and depression were compared.Statistical analysis were carried out by SPSS software(version 20.0).Results:Among all the patients with CRCI,males were more common.Also,there were statistically differences in marital status,liver metastasis,hypertension,ferritin(FER),high density lipoprotein-cholesterol(HDL-C),low density lipoprotein-cholesterol(LDL-C),NK cells,anxiety and depression(P<0.05).Conclusion:Part of patients with digestive tract cancer have varied degrees of cognitive dysfunction.Marital status,hypertension,immune function,liver metastasis and serum lipid metabolism were the risk factors for patients with digestive tract CRCI.Early identification of CRCI is of great significance to ensure the integrity of treatment,improve the quality of life and prognosis for patients with digestive tract CRCI.
文摘This study examined the influence of Big Five personality traits on Facebook usage and examined the interactions of traits in this context based on Torgersen’s (1995) typological approach. The effect of self-esteem, narcissism, loneliness, shyness and boredom proneness on Facebook usage was also investigated. The sample included both student (N = 190) and (N = 184) non-student samples. Narcissism was the strongest predictor of time spent on Facebook per day for both students and non-students. Narcissism was also the strongest predictor of number of daily logins for non-students, however, agreeableness was the strongest predictor of logins for students. Extraversion was the strongest predictor of number of Facebook friends for both students and non- students, however the interaction of Extraversion and Neuroticism was also a predictor of Facebook friends for students, and the interaction of Extraversion and Conscientiousness for non-students. Future research should consider the combined effect of personality traits on overall Facebook use.
