Higher education plays an important role in all aspects of sustainability.Infusing climate change and sustainability into the curriculum is important to prepare future health-care professionals for climate change and ...Higher education plays an important role in all aspects of sustainability.Infusing climate change and sustainability into the curriculum is important to prepare future health-care professionals for climate change and sustainability actions to build resilient health systems.In this study,we evaluated the preparedness,knowledge,and perception regarding climate change and its impact on human health among Indian nursing students.A quantitative descriptive survey was conducted among 644 undergraduate nursing students studying in three institutes in the southern,northern,and western parts of India.We used a structured online questionnaire with established validity and reliability to collect data.The data were analyzed using Statistical Package for the Social Sciences version 26 software.The results showed that more than half of the students reported experiencing excessive increase(362;56.2%)and decrease(374;58.1%)in temperature in recent years.Though more than three quarters of the students(494;76.7%)accepted the general truth that climate change is mainly caused by human activities,only less than half of the students(309;48.0%)perceived the impact of climate change to be high.Three quarters of the students(483;75.0%)had a high level of knowledge regarding climate change.The students who had a high level of knowledge about climate change exerted a high perceived impact of climate change(χ^(2)=75.47;P<0.01).More than half of the students(50.9%)felt that they needed information about climate change to be included in the nursing curriculum,and only one sixth of the students(16.1%)were highly confident about engaging in climate change-related conversation with patients.Most of the students who participated in the study had basic knowledge about climate change and its impact on human health.However,there is an observed gap between knowledge and their preparedness and confidence to engage in climate change actions.Hence,we propose to strengthen the nursing curriculum by integrating various curricular and co-curricular activities related to climate change,so that future nurses are empowered to become climate change advocates.展开更多
Polycyclic aromatic hydrocarbons(PAHs)are ubiquitous environmental contaminants of growing concern due to their potential ecological and human health risks.This study presents a comprehensive assessment of PAHs contam...Polycyclic aromatic hydrocarbons(PAHs)are ubiquitous environmental contaminants of growing concern due to their potential ecological and human health risks.This study presents a comprehensive assessment of PAHs contamination in the surface sediments of Burullus Lake,a vital and second largest delta lake in Egypt.The aim was to evaluate the eco-toxicity and potential health risks associated with the presence of these compounds.Surface seven sediment samples were collected from various drains in the southern part of Burullus Lake.Soxhlet extraction method was employed to extract PAHs(16PAHs)from the sediment sample.Analytically,target compounds were located using HPLC.The results showed that samples contained PAHs levels ranging from 0.038×10^(-6)to 0.459×10^(-6),which is considered heavily polluted by the European standard for PAHs pollution.Additionally,there was no apparent source of PAHs in the ElKhashah drain or the Brinbal Canal,as HPLC found none of the compounds.The most prevalent compound in sediment samples along the study area was fluoranthene.The diagnostic indices in the present study indicated that the hydrocarbons in the region originated from pyrolytic and man-made sources along the drains of Burullus Lake.The principal component analysis(PCA)and diagnostic ratios revealed that coal combustion and pyrolytic sources were responsible for the PAHs contamination in the surface sediments.The non-carcinogenic risk(HI),which is the product of the HQs for the adult and child populations,respectively,was calculated.HI values under 1,therefore,demonstrated that they had no carcinogenic effects on human health.TEQs and MEQs in the sediments of Burullus Lake do not have a cancer-causing impact on people.For the safety of nearby wildlife,aquatic life,and people,all activities that raise petroleum hydrocarbon levels in Burullus Lake must be adequately regulated and controlled.According to the ecological risk assessment,there is little chance that PAHs will be found in the sediments of Burullus Lake.This study underscores the urgent need for effective pollution control measures and regular monitoring of PAHs levels in Burullus Lake sediments to protect the aquatic ecosystem and public health.It also highlights the importance of considering eco-toxicity and human health risks in integrated risk assessments of PAHs-contaminated environments.展开更多
This study aims to reveal the occurrence and origin of typical groundwater with high arsenic and fluoride concentrations in the loess area of the Guanzhong Basin—a Neogene faulted basin.Key findings are as follows:(1...This study aims to reveal the occurrence and origin of typical groundwater with high arsenic and fluoride concentrations in the loess area of the Guanzhong Basin—a Neogene faulted basin.Key findings are as follows:(1)Groundwater samples with high arsenic and fluoride concentrations collected from the loess area and the terraces of the Weihe River accounted for 26%and 30%,respectively,of the total samples,with primary hydrochemical type identified as HCO_3-Na.The karst and sand areas exhibit relatively high groundwater quality,serving as preferred sources for water supply.It is recommended that local governments fully harness groundwater in these areas;(2)groundwater with high arsenic and fluoride concentrations in the loess area and the alluvial plain of rivers in Dali County is primarily distributed within the Guanzhong Basin,which represents the drainage zone of groundwater;(3)arsenic and fluoride in groundwater originate principally from natural and anthropogenic sources;(4)the human health risk assessments reveal that long-term intake of groundwater with high arsenic and fluoride concentrations pose cancer or non-cancer risks,which are more serious to kids compared to adults.This study provides a theoretical basis for the prevention and treatment of groundwater with high arsenic and fluoride concentrations in loess areas.展开更多
Background: Treatment non-adherence poses significant risks to health outcomes and impedes the health system’s efficiency, hence curtailing progress towards the end Tuberculosis (TB) strategy under SDG 3.3. Despite i...Background: Treatment non-adherence poses significant risks to health outcomes and impedes the health system’s efficiency, hence curtailing progress towards the end Tuberculosis (TB) strategy under SDG 3.3. Despite interventions to address TB treatment non-adherence, Kenya still reports high TB treatment non-adherence rates of 35% and consequently poor treatment outcome rates. Health Care Workers (HCWs) play a critical role in linking the population to health services, yet little is known of their influence on patients’ TB treatment non-adherence in Kenya. Objective: To analyze HCW-related factors associated with TB treatment non-adherence among patients in Kisumu East Sub-County. Methods: Health facility-based analytical cross-sectional mixed-method study. A Semi-structured questionnaire on treatment adherence and patients’ perceptions of HCWs during the clinic visit was administered to 102 consenting adult (out of a total census of 107 adults) drug-susceptible TB patients. 12 purposively selected HCWs by rank from 6 health facilities participated in Key Informant Interview sessions. Medication adherence was measured using the Morisky Medication Adherence Scale and then expressed as a dichotomous variable. Quantitative analysis utilized STATA version 15.1 while qualitative deductive thematic analysis was done using NVIVO version 14. Results: TB treatment non-adherence rate of 26% (CI: 18% - 36%) was recorded. Overall, patients who felt supported in dealing with the illness were 8 times more likely to adhere to treatment compared to those who were not (aOR = 7.947, 95% CI: 2.214 - 28.527, p = 0.001). Key HCW related factors influencing adherence to treatment included: friendliness (cOR = 4.31, 95% CI: 1.514 - 12.284, p = 0.006), respect (cOR = 6.679, 95% CI: 2.239 - 19.923, p = 0.001) and non-discriminatory service (cOR = 0.1478, 95% CI: 0.047 - 0.464, p = 0.001), communication [adequacy of consultation time (cOR = 6.563, 95% CI: 2.467 - 17.458, p = 0.001) and patients’ involvement in their health decisions (cOR = 3.02 95% CI: 1.061 - 8.592, p = 0.038)] and education and counselling (cOR = 4.371, 95% CI: 1.725 - 11.075, p = 0.002). Conclusion: The study results underline importance of patient-centered consultation for TB patients and targeted education and counselling for improved treatment adherence.展开更多
Ground-level ozone(O_(3)) aff ects vegetation and threatens environmental health when levels exceed critical values,above which adverse eff ects are expected.Cyprus is expected to be a hotspot for O_(3)concentrations ...Ground-level ozone(O_(3)) aff ects vegetation and threatens environmental health when levels exceed critical values,above which adverse eff ects are expected.Cyprus is expected to be a hotspot for O_(3)concentrations due to its unique position in the eastern Mediterranean,receiving air masses from Europe,African,and Asian continents,and experiencing a warm Mediterranean climate.In Cyprus,the spatiotemporal features of O_(3) are poorly understood and the potential risks for forest health have not been explored.We evaluated O_(3) and nitrogen oxides(NO and NO 2)at four regional background stations at different altitudes over 2014−2016.O_(3) risks to vegetation and human health were estimated by calculating accumulated O_(3)exposure over a threshold of 40 nmol mol^(−1)(AOT40)and cumulative exposure to mixing ratios above 35 nmol mol^(−1)(SOMO35)indices.The data reveal that mean O_(3)concentrations follow a seasonal pattern,with higher levels in spring(51.8 nmol mol^(−1))and summer(53.2 nmol mol^(−1))and lower levels in autumn(46.9 nmol mol^(−1))and winter(43.3 nmol mol^(−1)).The highest mean O_(3)exposure(59.5 nmol mol^(−1)) in summer occurred at the high elevation station Mt.Troodos(1819 m a.s.l.).Increasing(decreasing)altitudinal gradients were found for O_(3)(NO x),driven by summer–winter diff erences.The diurnal patterns of O_(3) showed little variation.Only at the lowest altitude O_(3) displayed a typical O_(3) diurnal pattern,with hourly diff erences smaller than 15 nmol mol^(−1).Accumulated O_(3) exposures at all stations and in all years exceeded the European Union’s limits for the protection of vegetation,with average values of 3-month(limit:3000 nmol mol^(−1)h)and 6-month(limit:5000 nmol mol^(−1)h)AOT40 for crops and forests of 16,564 and 31,836 nmol mol^(−1)h,respectively.O_(3) exposures were considerably high for human health,with an average SOMO35 value of 7270 nmol mol^(−1) days across stations and years.The results indicate that O_(3) is a major environmental and public health issue in Cyprus,and policies must be adopted to mitigate O_(3) precursor emissions at local and regional scales.展开更多
Chifeng is a concentrated mining area for non-ferrous metal minerals,as well as a key prevention and control area for heavyduty enterprises.This situation necessitates an efective ecological and human health risk asse...Chifeng is a concentrated mining area for non-ferrous metal minerals,as well as a key prevention and control area for heavyduty enterprises.This situation necessitates an efective ecological and human health risk assessment of heavy metal(loid)s driven by the wide distribution of metal ore processing,mining,and smelting factories in Hexigten Banner and Bairin Left Banner.We conducted surveys to assess the levels of heavy metal(loid)s(Cr,As,Pb,Cd,and Hg)in the topsoil and groundwater of the areas.The results indicated that the concentrations of As,Cd,and Pb in partial soil samples exceeded the environmental quality standards of Grade II.Based on contamination assessments,such as geoaccumulation indices and pollution indices,we inferred that Cd,Pb,and As were primary pollutants in topsoil.Potential ecological risks when considered as part of the average risk indices(RI)are up to 1626.40 and 2818.76,respectively,in the two areas.Comparative analysis revealed that Cd posed a very high potential ecological risk,followed by As.Moreover,the evaluation showed that the three exposure pathways of carcinogenic and non-carcinogenic risk followed a descending order:inhalation>ingestion>dermal contact,except for Pb.Arsenic in topsoil posed a potential non-carcinogenic risk to human health,while there were no adverse efects of As in groundwater.In addition,the average total carcinogenic risk for As in the two areas,as well as the risk of Pb in the topsoil of Bairin Left Banner and all the fve heavy metal(loid)s in groundwater,exceeded human tolerance.Pb–Zn mines caused higher human health risks.In addition,the tandem contamination of heavy metal(loid)s in soil and groundwater was not obvious.This research study provides a basis for pollution remediation to control heavy industry-induced ecological and health risks of heavy metal(loid)s.展开更多
Clean drinking water is one of the United Nations Sustainable Development Goals.Despite significant progress in the water purification technology,many regions still lack access to clean water.This paper provides a rev...Clean drinking water is one of the United Nations Sustainable Development Goals.Despite significant progress in the water purification technology,many regions still lack access to clean water.This paper provides a review of selected water contaminants and their impacts on human health.The World Health Organization(WHO)guidelines and regional standards for key contaminants were used to characterise water quality in the European Union and UK.The concept of safe drinking water was explained based on the non-observed adverse effect level,threshold concentrations for toxic chemicals,and their total daily intake.Various techniques for monitoring water contaminants and the drinking water standards from five different countries,including the UK,USA,Canada,Pakistan and India,were compared to WHO recommended guidelines.The literature on actual water quality in these regions and its potential health impacts was also discussed.Finally,the role of public water suppliers in identifying and monitoring drinking water contaminants in selected developed countries was presented as a potential guideline for developing countries.This review emphasised the need for a comprehensive understanding of water quality and its impacts on human health to ensure access to clean drinking water worldwide.展开更多
Background: Behind every great system is an organized team;this is especially true in the healthcare industry, where a dedicated human resources team can effectively recruit employees, train staff, and implement safet...Background: Behind every great system is an organized team;this is especially true in the healthcare industry, where a dedicated human resources team can effectively recruit employees, train staff, and implement safety measures in the workplace. The importance of human resources in the healthcare industry cannot be overstated, with benefits ranging from providing an orderly and effectively run facility to equipping staff with the most accurate and up-to-date training. Proper human resources management is critical in providing high-quality health care. A refocus on human resources management in healthcare requires more research to develop new policies. Effective human resources management strategies are greatly needed to achieve better outcomes and access to health care worldwide. Methods: This study leveraged NOI Polls census data on Health Facility Assessment for Lagos State. One thousand two hundred fifty-six health care facilities were assessed in Lagos State;numbers of Health workers were documented alongside their area of specialization. Also, demographic characterizations of the facilities, such as LGA, Ownership type, Facility Level Care, and Category of the facility, were also documented. Descriptive statistics alongside cross tabulation was done to present the various area of specialization of the health workers. Multiple response analysis was done to understand the distribution of human resources across the health facilities. At the same time, Chi-square and correlation tests were conducted to test the independence of various categories recorded while understanding the relationships among selected specialties. Results: The study revealed that Nurses were the most common health specialist in the Lagos State health facilities. At the same time, Gynecologists and General surgeons are the two medical specialists mostly common in health facilities. Midwives are the second most common health specialist working full time, while Generalist medical doctors make up the top three health specialists working full time. Nurses and Midwives had the highest number in Lagos State, while Pulmonologists were currently the lowest human resource available in Lagos State health care system. It was also noted that health facility distribution across Lagos’s urban and rural areas was even. In contrast, distribution based on other factors such as ownership type, Facility level of care, and facility category was slightly skewed. Conclusion: The distribution of health workers in health facility across LGA in Lagos State depend on Ownership type, Facility level of care, and category of the facility.展开更多
Lack of dietary fiber contributes to many health issues, particularly chronic vascular diseases. Mixed linkage β-1.3 - 1.4 beta-glucan (beta-glucan, in this paper) is a confirmed beneficial ingredient for the human d...Lack of dietary fiber contributes to many health issues, particularly chronic vascular diseases. Mixed linkage β-1.3 - 1.4 beta-glucan (beta-glucan, in this paper) is a confirmed beneficial ingredient for the human diet through reduction of cholesterol and the glycemic index. Barley contains the highest beta-glucan content of all the grains, and in this study, a percentage of flour from two high beta glucan lines was, each, added to an array of wheat-based food products to measure how it impacted total dietary fiber. Results showed that beta-glucan content was higher in all the products containing the added high beta-glucan flour, along with increased total dietary fiber content. Protein content in the food products is also increased with the higher protein in the barley flours added. Beta-glucan content in the barley-added products increased to 1.2% - 4.0% versus 0.2% - 0.5% in the pure wheat products, while the dietary fibers increased to 3.5% - 24.4% versus 2.1% - 9.1% in pure wheat product controls. This research provided experimental evidence that using a high beta-glucan barley ingredient in food can increase dietary fiber to benefit health.展开更多
In recent times, there are two kinds of completely opposite viewpoints about the impacts of nitrate on human health. To further objectively understand the effects of nitrate on human health, both of harmfulness and po...In recent times, there are two kinds of completely opposite viewpoints about the impacts of nitrate on human health. To further objectively understand the effects of nitrate on human health, both of harmfulness and possible benefits of nitrate to human body., it is discussed in this review from the aspects of nitrate accumulation in vegetables, the source of nitrate ingested into human body, and the transformation of nitrate in human body, as well as the pathogenesis and physiological functions of nitrate metabolism.展开更多
Objective To investigate the effect of ambient air pollution on human health and the subsequent disabillty-adjusted life years (DALYs) lost in Shanghai. Methods We used epidemiology-based exposure-response functions...Objective To investigate the effect of ambient air pollution on human health and the subsequent disabillty-adjusted life years (DALYs) lost in Shanghai. Methods We used epidemiology-based exposure-response functions to calculate the attributable number of cases due to air pollution in Shanghai in 2000, and then we estimated the corresponding DALYs lost in Shanghai based on unit DALYs values of the health consequences. Results Ambient air pollution caused 103 064 DALYs lost in Shanghai in 2000. Among all the health endpoints, premature deaths and chronic bronchitis predominated in the value of total DALYs lost. Conclusion The air pollution levels have an adverse effect on the general population health and strengthen the rationale for limiting the levels of air pollution in outdoor air in Shanghai.展开更多
In recent years,organoid technology,i.e.,in vitro three-dimensional(3D)tissue culture,has attracted increasing attention in biomedical engineering.Organoids are cell complexes induced by differentiation of stem cells ...In recent years,organoid technology,i.e.,in vitro three-dimensional(3D)tissue culture,has attracted increasing attention in biomedical engineering.Organoids are cell complexes induced by differentiation of stem cells or organ-progenitor cells in vitro using 3D culture technology.They can replicate the key structural and functional characteristics of the target organs in vivo.With the opening up of this new field of health engineering,there is a need for engineering-system approaches to the production,control,and quantitative analysis of organoids and their microenvironment.Traditional organoid technology has limitations,including lack of physical and chemical microenvironment control,high heterogeneity,complex manual operation,imperfect nutritional supply system,and lack of feasible online analytical technology for the organoids.The introduction of microfluidic chip technology into organoids has overcome many of these limitations and greatly expanded the scope of applications.Engineering organoid microfluidic system has become an interdisciplinary field in biomedical and health engineering.In this review,we summarize the development and culture system of organoids,discuss how microfluidic technology has been used to solve the main technical challenges in organoid research and development,and point out new opportunities and prospects for applications of organoid microfluidic system in drug development and screening,food safety,precision medicine,and other biomedical and health engineering fields.展开更多
In this study, a risk-based management model is developed and applied to an industrial zone. The models proposed by the United States Environmental Protection Agency and Han Bing have been improved by adding a residua...In this study, a risk-based management model is developed and applied to an industrial zone. The models proposed by the United States Environmental Protection Agency and Han Bing have been improved by adding a residual ratio of volatile organic compounds (VOC) after boiling and deleting the related parameters in half-life. Using this improved model, an integrated process was used to assess human health risk level in the study area. Compared with water quality analysis, the results highlight the importance of applying an integrated approach for decision making on risk levels and water protection. The results of this study demonstrated that: (1) Compared with these permissible level standards in China (GB 3838-2002) and National Primary Drinking Water Regulations of the United States, the residents' daily life had not been affected by the groundwater in this area (except for relative bad water quality of HB3-4 and HB3-6); (2) The typical detected organic contaminants of all groundwater samples were chloroform, carbon tetrachloride, trichloroethylene and tetrachloroethene, and the pollution sources were mainly industrial sources by preliminary investigations; (3) As for groundwater, the non-carcinogenic risk values of all samples do not exceed the permissible level of 1.0 and the carcinogenic risk values are relatively lower than the permissible level of 1.00E-06 to 1.00E-04; (4) Drinking water pathway of trichloroethylene and tetrachloroethylene mainly contribute to increasing the health risk of residents' in study areas; (5) In terms of non-carcinogenic risk and carcinogenic risk, the health risk order for drinking water pathway and dermal contact pathway was: drinking water pathway 〉 dermal contact pathway.展开更多
The paper briefly discusses the relationship between chronic diseases and gut health,and points out that an imbalance of intestinal microflora and an inadequate intake of dietary fiber are two important causes of chro...The paper briefly discusses the relationship between chronic diseases and gut health,and points out that an imbalance of intestinal microflora and an inadequate intake of dietary fiber are two important causes of chronic diseases.This paper also summarizes the research status of probiotic fermented fruit and vegetables,and discusses the main achievements of our group in this field and future developments of the related industry.The application of fermentation technology to fruit and vegetable processing and the development of a series of probiotic fermented fruit and vegetable products not only increase the added value of fruit and vegetables,but also organically combine probiotics and their active metabolites with prebiotics(dietary fiber,etc.),thereby promoting intestinal health as well as preventing and relieving chronic diseases.Fermentation technology provides a new approach to the study of the effect of probiotics on human health,and will have a revolutionary influence on probiotic application and on the fruit and vegetable processing industry.Thus,fruit and vegetable fermentation technology has excellent market potential.展开更多
Dietary fiber(DF)is believed to provide important health benefits and it has become a research hotspot.DF exists in most natural foods,including fruits(16.74%-91.24%),vegetables(6.53%-85.19%),grains(9.76%-69.20%)and s...Dietary fiber(DF)is believed to provide important health benefits and it has become a research hotspot.DF exists in most natural foods,including fruits(16.74%-91.24%),vegetables(6.53%-85.19%),grains(9.76%-69.20%)and so on.DF has different physicochemical properties such as water holding capacity(WHC)(2.01-25.03 g/g),water swelling capacity(WSC)(0.95-23.90 mL/g),oil holding capacity(OHC)(0.65-29.00 g/g),glucose adsorption capacity(GAC)(0.17-4.65 mmol/g),cholesterol adsorption capacity(CAC)(0.03-37.10 mg/g)and viscosity,which make it exhibits different physiological functions such as reducing the risk of obesity,diabetes,cancer,and intestinal diseases.On the basis of consulting related databases,the physicochemical properties of DF and its derived physiological functions are reviewed.It is found that DF has effect on the prevention and treatment of obesity due to good WHC,WSC,OHC and CAC.Good GAC can relieve the symptoms of diabetes.The physicochemical properties of WHC and WSC can reduce the risk of cancer.The WHC,WSC and viscosity are beneficial to intestinal health.展开更多
A substantial amount of emerging research is indicating that the gut microbiota has a significant impact on human health.Alterations of gut microbiota have clear consequences on intestinal homeostasis,physiology,gut m...A substantial amount of emerging research is indicating that the gut microbiota has a significant impact on human health.Alterations of gut microbiota have clear consequences on intestinal homeostasis,physiology,gut microbiome,immune system and host metabolic pathways.Diet composition plays an important role in the control of gut microbial populations and,thus,in the prevention,management and treatment of certain diseases such as cancer,diabetes.A comprehensive analysis of previously reported results revealed that the gut microbiota can be modulated by diet and the composition of gut microbiota can be influenced by various diet components.The symbiotic relationship between different gut microbial communities regulates the immune system and,therefore,any dysbiosis can dysregulate the immune system.Further research is needed to fully understand the mechanisms involved in the interactions between diet composition,gut microbiota and associated diseases.展开更多
The human body loading with arsenic(As)through rice consumption is a global health concern.There is a crucial need to limit As build-up in rice,either by remediating As accumulation in soils or reducing As levels in i...The human body loading with arsenic(As)through rice consumption is a global health concern.There is a crucial need to limit As build-up in rice,either by remediating As accumulation in soils or reducing As levels in irrigation water.Several conventional approaches have been utilized to alleviate the As accumulation in rice.However,except for some irrigation practices,those approaches success and the adoption rate are not remarkable.This review presents human health risks posed due to consumption of As contaminated rice,evaluates different biomarkers for tracing As loading in the human body,and discusses the latest advancement in As reducing technologies emphasizing the application of seed priming,nanotechnology,and biochar application for limiting As loading in rice grains.We also evaluate different irrigation techniques to reduce As accumulation in rice.Altering water management regimes significantly reduces grain As accumulation.Bio-and nano-priming of rice seeds improve germination and minimize As translocation in rice tissues by protecting cell membrane,building pool around seed coat,methylation and volatilization,or quenching harmful effects of reactive oxygen species.Nanoparticle application in the form of nano-adsorbents or nano-fertilizers facilitates nano-remediation of As through the formation of Fe plaque or sorption or oxidation process.Incorporating biochar in the rice fields significantly reduces As through immobilization,physical adsorption,or surface complexation.In conclusion,As content in cooked rice depends on irrigation source and raw rice As level.展开更多
This study aims to investigate the mechanisms and health risks of fluoride enrichment in groundwater in the Loess Plateau,China.By taking Dali County,Shaanxi Province,China as an example,this study obtains the followi...This study aims to investigate the mechanisms and health risks of fluoride enrichment in groundwater in the Loess Plateau,China.By taking Dali County,Shaanxi Province,China as an example,this study obtains the following results through field investigation and the analyses of water,soil,and crop samples.(1)The groundwater can be divided into two major types,namely the Quaternary pore-fissure water and Karst water.The Karst area and sandy area have high-quality groundwater and serve as the target areas for optional water supply.The groundwater in the study area is slightly alkaline and highly saline.Meanwhile,high-fluoride groundwater is mainly distributed in the loess and river alluvial plains in the depression area of the Guanzhong Basin and the discharge areas of the groundwater,with the highest fluoride concentration exceeding seven times the national standard.(2)Fluoride in groundwater mainly originates from a natural source and human activities.The natural source refers to the fluoride-bearing minerals in rocks and soil,and the fluoride from this source is mainly controlled by natural factors such as climate,geologic setting,pH,specific hydrochemical environment,ion exchange,and mineral saturation.Human activities in modern life can be further divided into industrial and agricultural sources primarily.(3)The health risks of fluoride contamination are very high in the Loess Plateau,especially for children compared to adults.Meanwhile,the risks of fluoride exposure through food intake are higher than those through drinking water intake.The authors suggest selecting target areas to improve water supply and ensure the safety of drinking water in the study area.Besides,it is necessary to plant crops with low fluoride content or cash crops and to conduct groundwater treatment to reduce the fluoride concentration in drinking water.These results will provide a theoretical basis for safe water supply in the faulted basin areas in the Loess Plateau.展开更多
The aim of this study was to evaluate groundwater fitness for domestic and irrigational use in Unnao district of Uttar Pradesh,India.For this study,block wise(n=16)groundwater samples were collected,and measured param...The aim of this study was to evaluate groundwater fitness for domestic and irrigational use in Unnao district of Uttar Pradesh,India.For this study,block wise(n=16)groundwater samples were collected,and measured parameters were analyzed using the pollution index of groundwater(PIG),various irrigational indices,and graphical techniques.The results of this study suggested that most of the parameters were within the prescribed limits of WHO and BIS,excluding F-(0.4 to 2.6 mg L^(-1))and Fe^(2+)(0.1 to 1.7 mg L^(-1)).Concentrations of total dissolved solids(TDS)were exceeded the desirable limit(>500 mg L^(-1))in 43.75%of samples at some sites.The Gibbs plot revealed that groundwater chemistry was governed by rock-water interaction in the region,especially silicate weathering.The Piper plot suggested that Ca^(2+)-HCO3-is dominant hydrochemical facies in the area followed by mixed Ca^(2+)-Na^(+)-HCO_(3)^(-)type,Na^(+)-Cl^(-)type,and Na^(+)-HCO_(3)^(-)type.PIG evaluation revealed that the contribution of F-and Fe2+in groundwater degradation is high in comparison to other elements in the region,about 18.75%samples showed low pollution,while about 6.25%samples shows moderate pollution,and 6.25%samples reflected high pollution.The human health risk(HHR)assessment finding suggested that children(mean:1.36)are more vulnerable than adults(mean:1.01).Sodium absorption ration(SAR),Residual sodium carbonate(RSC),and Permeability index(PI)indicated that most of the groundwater was suitable for irrigation,whereas,Magnesium hazard ration(MHR)and Potential salinity(PS)indices suggested that only 37.5%and 56.25%of the samples were suitable for irrigational use,respectively.This regional study would help in decision making for stakeholders and relevant authorities in the execution of groundwater management and remediation plans in the area.展开更多
Although chemical control of pests increases crop production, it brings a lot of damage to environment and human health. There exist a number of alternative methods that are not so harmful to environment and human hea...Although chemical control of pests increases crop production, it brings a lot of damage to environment and human health. There exist a number of alternative methods that are not so harmful to environment and human health. However, whether and how much in extent these technologies adopted are plausible depends on the comparison of benefit-cost between chemical control and the alternative control methods (such as Integrated Pest Management, IPM) and farmers' willingness-to-pay (WTP) for envirorment and human health. Using contingent valuation method (CVM), the author investigates farmers' WTP for environment and human health, recognizes the factors influencing WTP, and accordingly points out the importance of pest control technology extension and government regulation of pesticides.展开更多
文摘Higher education plays an important role in all aspects of sustainability.Infusing climate change and sustainability into the curriculum is important to prepare future health-care professionals for climate change and sustainability actions to build resilient health systems.In this study,we evaluated the preparedness,knowledge,and perception regarding climate change and its impact on human health among Indian nursing students.A quantitative descriptive survey was conducted among 644 undergraduate nursing students studying in three institutes in the southern,northern,and western parts of India.We used a structured online questionnaire with established validity and reliability to collect data.The data were analyzed using Statistical Package for the Social Sciences version 26 software.The results showed that more than half of the students reported experiencing excessive increase(362;56.2%)and decrease(374;58.1%)in temperature in recent years.Though more than three quarters of the students(494;76.7%)accepted the general truth that climate change is mainly caused by human activities,only less than half of the students(309;48.0%)perceived the impact of climate change to be high.Three quarters of the students(483;75.0%)had a high level of knowledge regarding climate change.The students who had a high level of knowledge about climate change exerted a high perceived impact of climate change(χ^(2)=75.47;P<0.01).More than half of the students(50.9%)felt that they needed information about climate change to be included in the nursing curriculum,and only one sixth of the students(16.1%)were highly confident about engaging in climate change-related conversation with patients.Most of the students who participated in the study had basic knowledge about climate change and its impact on human health.However,there is an observed gap between knowledge and their preparedness and confidence to engage in climate change actions.Hence,we propose to strengthen the nursing curriculum by integrating various curricular and co-curricular activities related to climate change,so that future nurses are empowered to become climate change advocates.
文摘Polycyclic aromatic hydrocarbons(PAHs)are ubiquitous environmental contaminants of growing concern due to their potential ecological and human health risks.This study presents a comprehensive assessment of PAHs contamination in the surface sediments of Burullus Lake,a vital and second largest delta lake in Egypt.The aim was to evaluate the eco-toxicity and potential health risks associated with the presence of these compounds.Surface seven sediment samples were collected from various drains in the southern part of Burullus Lake.Soxhlet extraction method was employed to extract PAHs(16PAHs)from the sediment sample.Analytically,target compounds were located using HPLC.The results showed that samples contained PAHs levels ranging from 0.038×10^(-6)to 0.459×10^(-6),which is considered heavily polluted by the European standard for PAHs pollution.Additionally,there was no apparent source of PAHs in the ElKhashah drain or the Brinbal Canal,as HPLC found none of the compounds.The most prevalent compound in sediment samples along the study area was fluoranthene.The diagnostic indices in the present study indicated that the hydrocarbons in the region originated from pyrolytic and man-made sources along the drains of Burullus Lake.The principal component analysis(PCA)and diagnostic ratios revealed that coal combustion and pyrolytic sources were responsible for the PAHs contamination in the surface sediments.The non-carcinogenic risk(HI),which is the product of the HQs for the adult and child populations,respectively,was calculated.HI values under 1,therefore,demonstrated that they had no carcinogenic effects on human health.TEQs and MEQs in the sediments of Burullus Lake do not have a cancer-causing impact on people.For the safety of nearby wildlife,aquatic life,and people,all activities that raise petroleum hydrocarbon levels in Burullus Lake must be adequately regulated and controlled.According to the ecological risk assessment,there is little chance that PAHs will be found in the sediments of Burullus Lake.This study underscores the urgent need for effective pollution control measures and regular monitoring of PAHs levels in Burullus Lake sediments to protect the aquatic ecosystem and public health.It also highlights the importance of considering eco-toxicity and human health risks in integrated risk assessments of PAHs-contaminated environments.
基金funded by the ministry-province cooperation-based pilot project entitled A Technological System for Ecological Remediation Evaluation of Open-Pit Mines initiated by the Ministry of Natural Resources in 2023(2023-03)survey projects of the Land and Resources Investigation Program([2023]06-03-04,1212010634713)a key R&D projects of Shaanxi Province in 2023(2023ZDLSF-63)。
文摘This study aims to reveal the occurrence and origin of typical groundwater with high arsenic and fluoride concentrations in the loess area of the Guanzhong Basin—a Neogene faulted basin.Key findings are as follows:(1)Groundwater samples with high arsenic and fluoride concentrations collected from the loess area and the terraces of the Weihe River accounted for 26%and 30%,respectively,of the total samples,with primary hydrochemical type identified as HCO_3-Na.The karst and sand areas exhibit relatively high groundwater quality,serving as preferred sources for water supply.It is recommended that local governments fully harness groundwater in these areas;(2)groundwater with high arsenic and fluoride concentrations in the loess area and the alluvial plain of rivers in Dali County is primarily distributed within the Guanzhong Basin,which represents the drainage zone of groundwater;(3)arsenic and fluoride in groundwater originate principally from natural and anthropogenic sources;(4)the human health risk assessments reveal that long-term intake of groundwater with high arsenic and fluoride concentrations pose cancer or non-cancer risks,which are more serious to kids compared to adults.This study provides a theoretical basis for the prevention and treatment of groundwater with high arsenic and fluoride concentrations in loess areas.
文摘Background: Treatment non-adherence poses significant risks to health outcomes and impedes the health system’s efficiency, hence curtailing progress towards the end Tuberculosis (TB) strategy under SDG 3.3. Despite interventions to address TB treatment non-adherence, Kenya still reports high TB treatment non-adherence rates of 35% and consequently poor treatment outcome rates. Health Care Workers (HCWs) play a critical role in linking the population to health services, yet little is known of their influence on patients’ TB treatment non-adherence in Kenya. Objective: To analyze HCW-related factors associated with TB treatment non-adherence among patients in Kisumu East Sub-County. Methods: Health facility-based analytical cross-sectional mixed-method study. A Semi-structured questionnaire on treatment adherence and patients’ perceptions of HCWs during the clinic visit was administered to 102 consenting adult (out of a total census of 107 adults) drug-susceptible TB patients. 12 purposively selected HCWs by rank from 6 health facilities participated in Key Informant Interview sessions. Medication adherence was measured using the Morisky Medication Adherence Scale and then expressed as a dichotomous variable. Quantitative analysis utilized STATA version 15.1 while qualitative deductive thematic analysis was done using NVIVO version 14. Results: TB treatment non-adherence rate of 26% (CI: 18% - 36%) was recorded. Overall, patients who felt supported in dealing with the illness were 8 times more likely to adhere to treatment compared to those who were not (aOR = 7.947, 95% CI: 2.214 - 28.527, p = 0.001). Key HCW related factors influencing adherence to treatment included: friendliness (cOR = 4.31, 95% CI: 1.514 - 12.284, p = 0.006), respect (cOR = 6.679, 95% CI: 2.239 - 19.923, p = 0.001) and non-discriminatory service (cOR = 0.1478, 95% CI: 0.047 - 0.464, p = 0.001), communication [adequacy of consultation time (cOR = 6.563, 95% CI: 2.467 - 17.458, p = 0.001) and patients’ involvement in their health decisions (cOR = 3.02 95% CI: 1.061 - 8.592, p = 0.038)] and education and counselling (cOR = 4.371, 95% CI: 1.725 - 11.075, p = 0.002). Conclusion: The study results underline importance of patient-centered consultation for TB patients and targeted education and counselling for improved treatment adherence.
基金supported by the National Natural Science Foundation of China(NSFC)(No.4210070867)the Foreign Young Talents Fund of the National Ministry of Science and Technology,China(No.31950410547)+1 种基金The Startup Foundation for Introducing Talent of Nanjing University of Information Science&Technology(NUIST),Nanjing,China(No.003080)the Jiangsu Distinguished Professor program of the People’s Government of Jiangsu Province,China.
文摘Ground-level ozone(O_(3)) aff ects vegetation and threatens environmental health when levels exceed critical values,above which adverse eff ects are expected.Cyprus is expected to be a hotspot for O_(3)concentrations due to its unique position in the eastern Mediterranean,receiving air masses from Europe,African,and Asian continents,and experiencing a warm Mediterranean climate.In Cyprus,the spatiotemporal features of O_(3) are poorly understood and the potential risks for forest health have not been explored.We evaluated O_(3) and nitrogen oxides(NO and NO 2)at four regional background stations at different altitudes over 2014−2016.O_(3) risks to vegetation and human health were estimated by calculating accumulated O_(3)exposure over a threshold of 40 nmol mol^(−1)(AOT40)and cumulative exposure to mixing ratios above 35 nmol mol^(−1)(SOMO35)indices.The data reveal that mean O_(3)concentrations follow a seasonal pattern,with higher levels in spring(51.8 nmol mol^(−1))and summer(53.2 nmol mol^(−1))and lower levels in autumn(46.9 nmol mol^(−1))and winter(43.3 nmol mol^(−1)).The highest mean O_(3)exposure(59.5 nmol mol^(−1)) in summer occurred at the high elevation station Mt.Troodos(1819 m a.s.l.).Increasing(decreasing)altitudinal gradients were found for O_(3)(NO x),driven by summer–winter diff erences.The diurnal patterns of O_(3) showed little variation.Only at the lowest altitude O_(3) displayed a typical O_(3) diurnal pattern,with hourly diff erences smaller than 15 nmol mol^(−1).Accumulated O_(3) exposures at all stations and in all years exceeded the European Union’s limits for the protection of vegetation,with average values of 3-month(limit:3000 nmol mol^(−1)h)and 6-month(limit:5000 nmol mol^(−1)h)AOT40 for crops and forests of 16,564 and 31,836 nmol mol^(−1)h,respectively.O_(3) exposures were considerably high for human health,with an average SOMO35 value of 7270 nmol mol^(−1) days across stations and years.The results indicate that O_(3) is a major environmental and public health issue in Cyprus,and policies must be adopted to mitigate O_(3) precursor emissions at local and regional scales.
基金the National Natural Science Foundation of China(No.42072284,No.42027801,No.41877186)the National Key R&D Program of China(2021YFC2902004)+1 种基金the Major Science and Technology Projects of Inner Mongolia Autonomous Region(2020ZD0020-4)the Fundamental Research Funds for the Central Universities(2022YQSH01,2020YJSSH01,2021YJSSH01)。
文摘Chifeng is a concentrated mining area for non-ferrous metal minerals,as well as a key prevention and control area for heavyduty enterprises.This situation necessitates an efective ecological and human health risk assessment of heavy metal(loid)s driven by the wide distribution of metal ore processing,mining,and smelting factories in Hexigten Banner and Bairin Left Banner.We conducted surveys to assess the levels of heavy metal(loid)s(Cr,As,Pb,Cd,and Hg)in the topsoil and groundwater of the areas.The results indicated that the concentrations of As,Cd,and Pb in partial soil samples exceeded the environmental quality standards of Grade II.Based on contamination assessments,such as geoaccumulation indices and pollution indices,we inferred that Cd,Pb,and As were primary pollutants in topsoil.Potential ecological risks when considered as part of the average risk indices(RI)are up to 1626.40 and 2818.76,respectively,in the two areas.Comparative analysis revealed that Cd posed a very high potential ecological risk,followed by As.Moreover,the evaluation showed that the three exposure pathways of carcinogenic and non-carcinogenic risk followed a descending order:inhalation>ingestion>dermal contact,except for Pb.Arsenic in topsoil posed a potential non-carcinogenic risk to human health,while there were no adverse efects of As in groundwater.In addition,the average total carcinogenic risk for As in the two areas,as well as the risk of Pb in the topsoil of Bairin Left Banner and all the fve heavy metal(loid)s in groundwater,exceeded human tolerance.Pb–Zn mines caused higher human health risks.In addition,the tandem contamination of heavy metal(loid)s in soil and groundwater was not obvious.This research study provides a basis for pollution remediation to control heavy industry-induced ecological and health risks of heavy metal(loid)s.
文摘Clean drinking water is one of the United Nations Sustainable Development Goals.Despite significant progress in the water purification technology,many regions still lack access to clean water.This paper provides a review of selected water contaminants and their impacts on human health.The World Health Organization(WHO)guidelines and regional standards for key contaminants were used to characterise water quality in the European Union and UK.The concept of safe drinking water was explained based on the non-observed adverse effect level,threshold concentrations for toxic chemicals,and their total daily intake.Various techniques for monitoring water contaminants and the drinking water standards from five different countries,including the UK,USA,Canada,Pakistan and India,were compared to WHO recommended guidelines.The literature on actual water quality in these regions and its potential health impacts was also discussed.Finally,the role of public water suppliers in identifying and monitoring drinking water contaminants in selected developed countries was presented as a potential guideline for developing countries.This review emphasised the need for a comprehensive understanding of water quality and its impacts on human health to ensure access to clean drinking water worldwide.
文摘Background: Behind every great system is an organized team;this is especially true in the healthcare industry, where a dedicated human resources team can effectively recruit employees, train staff, and implement safety measures in the workplace. The importance of human resources in the healthcare industry cannot be overstated, with benefits ranging from providing an orderly and effectively run facility to equipping staff with the most accurate and up-to-date training. Proper human resources management is critical in providing high-quality health care. A refocus on human resources management in healthcare requires more research to develop new policies. Effective human resources management strategies are greatly needed to achieve better outcomes and access to health care worldwide. Methods: This study leveraged NOI Polls census data on Health Facility Assessment for Lagos State. One thousand two hundred fifty-six health care facilities were assessed in Lagos State;numbers of Health workers were documented alongside their area of specialization. Also, demographic characterizations of the facilities, such as LGA, Ownership type, Facility Level Care, and Category of the facility, were also documented. Descriptive statistics alongside cross tabulation was done to present the various area of specialization of the health workers. Multiple response analysis was done to understand the distribution of human resources across the health facilities. At the same time, Chi-square and correlation tests were conducted to test the independence of various categories recorded while understanding the relationships among selected specialties. Results: The study revealed that Nurses were the most common health specialist in the Lagos State health facilities. At the same time, Gynecologists and General surgeons are the two medical specialists mostly common in health facilities. Midwives are the second most common health specialist working full time, while Generalist medical doctors make up the top three health specialists working full time. Nurses and Midwives had the highest number in Lagos State, while Pulmonologists were currently the lowest human resource available in Lagos State health care system. It was also noted that health facility distribution across Lagos’s urban and rural areas was even. In contrast, distribution based on other factors such as ownership type, Facility level of care, and facility category was slightly skewed. Conclusion: The distribution of health workers in health facility across LGA in Lagos State depend on Ownership type, Facility level of care, and category of the facility.
文摘Lack of dietary fiber contributes to many health issues, particularly chronic vascular diseases. Mixed linkage β-1.3 - 1.4 beta-glucan (beta-glucan, in this paper) is a confirmed beneficial ingredient for the human diet through reduction of cholesterol and the glycemic index. Barley contains the highest beta-glucan content of all the grains, and in this study, a percentage of flour from two high beta glucan lines was, each, added to an array of wheat-based food products to measure how it impacted total dietary fiber. Results showed that beta-glucan content was higher in all the products containing the added high beta-glucan flour, along with increased total dietary fiber content. Protein content in the food products is also increased with the higher protein in the barley flours added. Beta-glucan content in the barley-added products increased to 1.2% - 4.0% versus 0.2% - 0.5% in the pure wheat products, while the dietary fibers increased to 3.5% - 24.4% versus 2.1% - 9.1% in pure wheat product controls. This research provided experimental evidence that using a high beta-glucan barley ingredient in food can increase dietary fiber to benefit health.
基金the Program for Changjiang Schlors and Innovative Research Team in University, China (IRT0536) the National Basic Research Program of China (973 Program, 2002CB410806)+1 种基金 the National Natural Science Foundation of China (NSFC, 30571083) the Natural Science Foundation of Zhejiang Province, China (Z303465).
文摘In recent times, there are two kinds of completely opposite viewpoints about the impacts of nitrate on human health. To further objectively understand the effects of nitrate on human health, both of harmfulness and possible benefits of nitrate to human body., it is discussed in this review from the aspects of nitrate accumulation in vegetables, the source of nitrate ingested into human body, and the transformation of nitrate in human body, as well as the pathogenesis and physiological functions of nitrate metabolism.
基金This work was supported by Energy Foundation through Grant G-0309-07094 and Shanghai Municipal Committee of Science and Technology through Grant 03DZ05052. Hai-Dong KAN was personally supported by Shanghai Rising-Star Program for Young Investigators (04QMX1402).
文摘Objective To investigate the effect of ambient air pollution on human health and the subsequent disabillty-adjusted life years (DALYs) lost in Shanghai. Methods We used epidemiology-based exposure-response functions to calculate the attributable number of cases due to air pollution in Shanghai in 2000, and then we estimated the corresponding DALYs lost in Shanghai based on unit DALYs values of the health consequences. Results Ambient air pollution caused 103 064 DALYs lost in Shanghai in 2000. Among all the health endpoints, premature deaths and chronic bronchitis predominated in the value of total DALYs lost. Conclusion The air pollution levels have an adverse effect on the general population health and strengthen the rationale for limiting the levels of air pollution in outdoor air in Shanghai.
基金This work was supported by the Key Areas Research Development Projects of Guangdong Province(No.2019B020210001)the Tsinghua-U Tokyo Collaborative Research Fund(No.20193080052)the Key Areas Research Development Projects of Hebei Province(No.20375502D).
文摘In recent years,organoid technology,i.e.,in vitro three-dimensional(3D)tissue culture,has attracted increasing attention in biomedical engineering.Organoids are cell complexes induced by differentiation of stem cells or organ-progenitor cells in vitro using 3D culture technology.They can replicate the key structural and functional characteristics of the target organs in vivo.With the opening up of this new field of health engineering,there is a need for engineering-system approaches to the production,control,and quantitative analysis of organoids and their microenvironment.Traditional organoid technology has limitations,including lack of physical and chemical microenvironment control,high heterogeneity,complex manual operation,imperfect nutritional supply system,and lack of feasible online analytical technology for the organoids.The introduction of microfluidic chip technology into organoids has overcome many of these limitations and greatly expanded the scope of applications.Engineering organoid microfluidic system has become an interdisciplinary field in biomedical and health engineering.In this review,we summarize the development and culture system of organoids,discuss how microfluidic technology has been used to solve the main technical challenges in organoid research and development,and point out new opportunities and prospects for applications of organoid microfluidic system in drug development and screening,food safety,precision medicine,and other biomedical and health engineering fields.
基金supported by National Science and Technology Major Project(No2009 ZX 05039-003,2009 ZX 05039-004,2011ZX05060-005)the National Natural Science Foundation of China(No 2010CB428801-1)state-owned land resources investigation(1212010430351)
文摘In this study, a risk-based management model is developed and applied to an industrial zone. The models proposed by the United States Environmental Protection Agency and Han Bing have been improved by adding a residual ratio of volatile organic compounds (VOC) after boiling and deleting the related parameters in half-life. Using this improved model, an integrated process was used to assess human health risk level in the study area. Compared with water quality analysis, the results highlight the importance of applying an integrated approach for decision making on risk levels and water protection. The results of this study demonstrated that: (1) Compared with these permissible level standards in China (GB 3838-2002) and National Primary Drinking Water Regulations of the United States, the residents' daily life had not been affected by the groundwater in this area (except for relative bad water quality of HB3-4 and HB3-6); (2) The typical detected organic contaminants of all groundwater samples were chloroform, carbon tetrachloride, trichloroethylene and tetrachloroethene, and the pollution sources were mainly industrial sources by preliminary investigations; (3) As for groundwater, the non-carcinogenic risk values of all samples do not exceed the permissible level of 1.0 and the carcinogenic risk values are relatively lower than the permissible level of 1.00E-06 to 1.00E-04; (4) Drinking water pathway of trichloroethylene and tetrachloroethylene mainly contribute to increasing the health risk of residents' in study areas; (5) In terms of non-carcinogenic risk and carcinogenic risk, the health risk order for drinking water pathway and dermal contact pathway was: drinking water pathway 〉 dermal contact pathway.
基金Financial support from the National Key Research and Development Program of China(2017YFD0400705-2,2017YFD0400503-3)the National Natural Science Foundation of China(31560449 and 31760457)the Jiangxi Provincial Key Research and Development Project(20165ABC28004)are gratefully acknowledged.
文摘The paper briefly discusses the relationship between chronic diseases and gut health,and points out that an imbalance of intestinal microflora and an inadequate intake of dietary fiber are two important causes of chronic diseases.This paper also summarizes the research status of probiotic fermented fruit and vegetables,and discusses the main achievements of our group in this field and future developments of the related industry.The application of fermentation technology to fruit and vegetable processing and the development of a series of probiotic fermented fruit and vegetable products not only increase the added value of fruit and vegetables,but also organically combine probiotics and their active metabolites with prebiotics(dietary fiber,etc.),thereby promoting intestinal health as well as preventing and relieving chronic diseases.Fermentation technology provides a new approach to the study of the effect of probiotics on human health,and will have a revolutionary influence on probiotic application and on the fruit and vegetable processing industry.Thus,fruit and vegetable fermentation technology has excellent market potential.
基金supported by China Agriculture Research System of MOF and MARA(CARS-04).
文摘Dietary fiber(DF)is believed to provide important health benefits and it has become a research hotspot.DF exists in most natural foods,including fruits(16.74%-91.24%),vegetables(6.53%-85.19%),grains(9.76%-69.20%)and so on.DF has different physicochemical properties such as water holding capacity(WHC)(2.01-25.03 g/g),water swelling capacity(WSC)(0.95-23.90 mL/g),oil holding capacity(OHC)(0.65-29.00 g/g),glucose adsorption capacity(GAC)(0.17-4.65 mmol/g),cholesterol adsorption capacity(CAC)(0.03-37.10 mg/g)and viscosity,which make it exhibits different physiological functions such as reducing the risk of obesity,diabetes,cancer,and intestinal diseases.On the basis of consulting related databases,the physicochemical properties of DF and its derived physiological functions are reviewed.It is found that DF has effect on the prevention and treatment of obesity due to good WHC,WSC,OHC and CAC.Good GAC can relieve the symptoms of diabetes.The physicochemical properties of WHC and WSC can reduce the risk of cancer.The WHC,WSC and viscosity are beneficial to intestinal health.
基金This study was supported by the National Key Technology R&D Program(grant number 2015BAD16B02)the National Natural Science Foundation of China(NSFC)(grant number 31201408 and 31471718).
文摘A substantial amount of emerging research is indicating that the gut microbiota has a significant impact on human health.Alterations of gut microbiota have clear consequences on intestinal homeostasis,physiology,gut microbiome,immune system and host metabolic pathways.Diet composition plays an important role in the control of gut microbial populations and,thus,in the prevention,management and treatment of certain diseases such as cancer,diabetes.A comprehensive analysis of previously reported results revealed that the gut microbiota can be modulated by diet and the composition of gut microbiota can be influenced by various diet components.The symbiotic relationship between different gut microbial communities regulates the immune system and,therefore,any dysbiosis can dysregulate the immune system.Further research is needed to fully understand the mechanisms involved in the interactions between diet composition,gut microbiota and associated diseases.
基金the Seed Funding Grant(Grant No.RG53/19-20R)General Research Fund Proposal(Grant No.RG21/2020-2021R)+1 种基金Dean’s Research Fund(Grant No.IRS-10-2020)Department of Science and Environmental Studies Grant for Collaborative Research Project of the Education University of Hong Kong,China(Grant No.04487).
文摘The human body loading with arsenic(As)through rice consumption is a global health concern.There is a crucial need to limit As build-up in rice,either by remediating As accumulation in soils or reducing As levels in irrigation water.Several conventional approaches have been utilized to alleviate the As accumulation in rice.However,except for some irrigation practices,those approaches success and the adoption rate are not remarkable.This review presents human health risks posed due to consumption of As contaminated rice,evaluates different biomarkers for tracing As loading in the human body,and discusses the latest advancement in As reducing technologies emphasizing the application of seed priming,nanotechnology,and biochar application for limiting As loading in rice grains.We also evaluate different irrigation techniques to reduce As accumulation in rice.Altering water management regimes significantly reduces grain As accumulation.Bio-and nano-priming of rice seeds improve germination and minimize As translocation in rice tissues by protecting cell membrane,building pool around seed coat,methylation and volatilization,or quenching harmful effects of reactive oxygen species.Nanoparticle application in the form of nano-adsorbents or nano-fertilizers facilitates nano-remediation of As through the formation of Fe plaque or sorption or oxidation process.Incorporating biochar in the rice fields significantly reduces As through immobilization,physical adsorption,or surface complexation.In conclusion,As content in cooked rice depends on irrigation source and raw rice As level.
基金This study was funded by the survey projects initiated by the China Geological Survey(DD20189220,DD20211317,and 1212010634713).
文摘This study aims to investigate the mechanisms and health risks of fluoride enrichment in groundwater in the Loess Plateau,China.By taking Dali County,Shaanxi Province,China as an example,this study obtains the following results through field investigation and the analyses of water,soil,and crop samples.(1)The groundwater can be divided into two major types,namely the Quaternary pore-fissure water and Karst water.The Karst area and sandy area have high-quality groundwater and serve as the target areas for optional water supply.The groundwater in the study area is slightly alkaline and highly saline.Meanwhile,high-fluoride groundwater is mainly distributed in the loess and river alluvial plains in the depression area of the Guanzhong Basin and the discharge areas of the groundwater,with the highest fluoride concentration exceeding seven times the national standard.(2)Fluoride in groundwater mainly originates from a natural source and human activities.The natural source refers to the fluoride-bearing minerals in rocks and soil,and the fluoride from this source is mainly controlled by natural factors such as climate,geologic setting,pH,specific hydrochemical environment,ion exchange,and mineral saturation.Human activities in modern life can be further divided into industrial and agricultural sources primarily.(3)The health risks of fluoride contamination are very high in the Loess Plateau,especially for children compared to adults.Meanwhile,the risks of fluoride exposure through food intake are higher than those through drinking water intake.The authors suggest selecting target areas to improve water supply and ensure the safety of drinking water in the study area.Besides,it is necessary to plant crops with low fluoride content or cash crops and to conduct groundwater treatment to reduce the fluoride concentration in drinking water.These results will provide a theoretical basis for safe water supply in the faulted basin areas in the Loess Plateau.
文摘The aim of this study was to evaluate groundwater fitness for domestic and irrigational use in Unnao district of Uttar Pradesh,India.For this study,block wise(n=16)groundwater samples were collected,and measured parameters were analyzed using the pollution index of groundwater(PIG),various irrigational indices,and graphical techniques.The results of this study suggested that most of the parameters were within the prescribed limits of WHO and BIS,excluding F-(0.4 to 2.6 mg L^(-1))and Fe^(2+)(0.1 to 1.7 mg L^(-1)).Concentrations of total dissolved solids(TDS)were exceeded the desirable limit(>500 mg L^(-1))in 43.75%of samples at some sites.The Gibbs plot revealed that groundwater chemistry was governed by rock-water interaction in the region,especially silicate weathering.The Piper plot suggested that Ca^(2+)-HCO3-is dominant hydrochemical facies in the area followed by mixed Ca^(2+)-Na^(+)-HCO_(3)^(-)type,Na^(+)-Cl^(-)type,and Na^(+)-HCO_(3)^(-)type.PIG evaluation revealed that the contribution of F-and Fe2+in groundwater degradation is high in comparison to other elements in the region,about 18.75%samples showed low pollution,while about 6.25%samples shows moderate pollution,and 6.25%samples reflected high pollution.The human health risk(HHR)assessment finding suggested that children(mean:1.36)are more vulnerable than adults(mean:1.01).Sodium absorption ration(SAR),Residual sodium carbonate(RSC),and Permeability index(PI)indicated that most of the groundwater was suitable for irrigation,whereas,Magnesium hazard ration(MHR)and Potential salinity(PS)indices suggested that only 37.5%and 56.25%of the samples were suitable for irrigational use,respectively.This regional study would help in decision making for stakeholders and relevant authorities in the execution of groundwater management and remediation plans in the area.
基金This research is funded by Natural Science Fund of China. No. 70203001
文摘Although chemical control of pests increases crop production, it brings a lot of damage to environment and human health. There exist a number of alternative methods that are not so harmful to environment and human health. However, whether and how much in extent these technologies adopted are plausible depends on the comparison of benefit-cost between chemical control and the alternative control methods (such as Integrated Pest Management, IPM) and farmers' willingness-to-pay (WTP) for envirorment and human health. Using contingent valuation method (CVM), the author investigates farmers' WTP for environment and human health, recognizes the factors influencing WTP, and accordingly points out the importance of pest control technology extension and government regulation of pesticides.