目的:探讨火龙罐辅助治疗心肺气虚、血瘀饮停慢性心力衰竭(chronic heart failure,CHF)患者的效果。方法:选择2022年2月—2023年8月厦门市中医院心血管科确诊的120例心肺气虚、血瘀饮停CHF患者作为研究对象,按照随机数表法将患者分为两...目的:探讨火龙罐辅助治疗心肺气虚、血瘀饮停慢性心力衰竭(chronic heart failure,CHF)患者的效果。方法:选择2022年2月—2023年8月厦门市中医院心血管科确诊的120例心肺气虚、血瘀饮停CHF患者作为研究对象,按照随机数表法将患者分为两组,每组60例。对照组接受常规西医治疗,观察组在此基础实施火龙罐辅助治疗,比较两组治疗前后心功能分级、中医症候积分、明尼苏达心力衰竭生活质量问卷(Minnesota living heart failure questionnaire,MLHFQ)评分、N末端B型脑钠尿肽前体(N terminal pro B type natriuretic peptide,NT-proBNP)水平、临床效果及随访6个月再住院情况。结果:观察组治疗后心功能分级低于对照组,差异有统计学意义(P<0.05);观察组治疗后中医症候积分、MLHFQ评分、NT-proBNP水平低于对照组,且观察组治疗前后中医症候积分、MLHFQ评分、NT-proBNP差值大于对照组,差异有统计学意义(P<0.05);观察组临床效果优于对照组,差异有统计学意义(P<0.05);两组随访6个月再住院率比较,差异无统计学意义(P>0.05)。结论:火龙罐辅助治疗有助于改善心肺气虚、血瘀饮停CHF患者心功能分级、中医症候积分,提升生活质量,降低NT-proBNP水平,提高临床效果。展开更多
Left ventricular assist device( LVAD) in this study is a mechanical tool that is used to support blood flow in the patient with heart disease. It supports left ventricle by building up the pressure to the pump outlet ...Left ventricular assist device( LVAD) in this study is a mechanical tool that is used to support blood flow in the patient with heart disease. It supports left ventricle by building up the pressure to the pump outlet connected to the aorta. This pump was designed based on the magnetic driven centrifugal pump with a unique small washout hole constructed inside the impeller to generate the washout flow passage to prevent the stagnation at the region underneath and around the rotor. Computational fluid dynamics( CFD) was adopted in this study to assess the performance and optimize the design to avoid recirculation and high shear stress which is the main cause of stagnation and blood damage. Transient simulation was used for this study due to the asymmetric design of the washout hole and the complication of the bottom support of the impeller that has a risk of thrombosis,also,it was used to predict the variation of hydraulic performance caused by the rotation of the impeller and pulsed flow at the pump inlet. The simulation results show no excessive stress and no recirculation observed within the computational domain; in addition,the research result also provides information for further optimization and development to the pump.展开更多
文摘目的:探讨火龙罐辅助治疗心肺气虚、血瘀饮停慢性心力衰竭(chronic heart failure,CHF)患者的效果。方法:选择2022年2月—2023年8月厦门市中医院心血管科确诊的120例心肺气虚、血瘀饮停CHF患者作为研究对象,按照随机数表法将患者分为两组,每组60例。对照组接受常规西医治疗,观察组在此基础实施火龙罐辅助治疗,比较两组治疗前后心功能分级、中医症候积分、明尼苏达心力衰竭生活质量问卷(Minnesota living heart failure questionnaire,MLHFQ)评分、N末端B型脑钠尿肽前体(N terminal pro B type natriuretic peptide,NT-proBNP)水平、临床效果及随访6个月再住院情况。结果:观察组治疗后心功能分级低于对照组,差异有统计学意义(P<0.05);观察组治疗后中医症候积分、MLHFQ评分、NT-proBNP水平低于对照组,且观察组治疗前后中医症候积分、MLHFQ评分、NT-proBNP差值大于对照组,差异有统计学意义(P<0.05);观察组临床效果优于对照组,差异有统计学意义(P<0.05);两组随访6个月再住院率比较,差异无统计学意义(P>0.05)。结论:火龙罐辅助治疗有助于改善心肺气虚、血瘀饮停CHF患者心功能分级、中医症候积分,提升生活质量,降低NT-proBNP水平,提高临床效果。
文摘Left ventricular assist device( LVAD) in this study is a mechanical tool that is used to support blood flow in the patient with heart disease. It supports left ventricle by building up the pressure to the pump outlet connected to the aorta. This pump was designed based on the magnetic driven centrifugal pump with a unique small washout hole constructed inside the impeller to generate the washout flow passage to prevent the stagnation at the region underneath and around the rotor. Computational fluid dynamics( CFD) was adopted in this study to assess the performance and optimize the design to avoid recirculation and high shear stress which is the main cause of stagnation and blood damage. Transient simulation was used for this study due to the asymmetric design of the washout hole and the complication of the bottom support of the impeller that has a risk of thrombosis,also,it was used to predict the variation of hydraulic performance caused by the rotation of the impeller and pulsed flow at the pump inlet. The simulation results show no excessive stress and no recirculation observed within the computational domain; in addition,the research result also provides information for further optimization and development to the pump.
