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Operating Parameters of the District Heating Substation Cooperating With the Installation of Technological Air Conditioning With High Efficiency of Heat Recovery
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作者 Żarski Kazimierz Kryża Mariusz 《Chinese Business Review》 2024年第1期1-12,共12页
The article analyses the problem of determining the operating parameters of the district heating substation cooperating with the air heating system in technological air conditioning systems equipped with heat exchange... The article analyses the problem of determining the operating parameters of the district heating substation cooperating with the air heating system in technological air conditioning systems equipped with heat exchangers with high efficiency of heat recovery.Attention was paid to the correct selection of heat exchangers for the heat output balance depending on the heat recovery protection algorithms against a drop in the temperature of the heat transfer surface below 0℃.Critical parameters were determined in Polish climatic conditions,at which the operation of the heat recovery exchanger in the air conditioning system is switched off or limited.It has been proven that the proper functioning of the district heating substation cooperating with the installation of air conditioning with high heat recovery efficiency requires the use of two heat exchangers with different characteristics,equipped with properly selected temperature control systems.The optimal model of cooperation between the technological air conditioning system and the heating substation was also indicated. 展开更多
关键词 ventilation of operating theatre air conditioning flow control in heating circuit
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Heat absorption control equation and its application of cool-wall cooling system in mines 被引量:2
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作者 CHANG Zhang-yu JI Jing-wei +2 位作者 WANG Ke-yi NI Lu LI Ning-ning 《Journal of Central South University》 SCIE EI CAS CSCD 2021年第9期2735-2751,共17页
In order to solve the heat damages in deep mines, a cool-wall cooling technology and its working model are proposed based on the principles of heat absorption and insulation in this paper. During this process, the dif... In order to solve the heat damages in deep mines, a cool-wall cooling technology and its working model are proposed based on the principles of heat absorption and insulation in this paper. During this process, the differential equation of thermal equilibrium for roadway control unit is built, and the heat adsorption control equation of cool-wall cooling system is derived by an integral method, so as to obtain the quantitative relationship among the heat absorption capacity of cooling system, the heat dissipating capacity of surrounding rock and air temperature change. Then, the heat absorption capacity required by air temperature less than the standard value for safety is figured out by section iterative method with the simultaneous solution of heat absorption control equation and the heat dissipation density equation of surrounding rock. Finally, the results show that as the air temperature at the inlet of roadway is 25 ℃, the roadway wall is covered by heat-absorbing plate up to 39% of the area, as well as the cold water is injected into the heat-absorbing plate with a temperature of 20 ℃ and a mass flow of 113.6 kg/s, the air flow temperature rise per kilometer in the roadway can be less than 3 ℃. 展开更多
关键词 cold-wall cooling system heat absorption control equation heat dissipation boundary conditions safe thermal environment system design
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Application of dynamic programming algorithm in winter heating control of greenhouse
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作者 Fei Gao Hongbin Tu +5 位作者 Delan Zhu Mengyang Liu Changyang Shi Rui Zhang Ruixin Wang Zhu Li 《International Journal of Agricultural and Biological Engineering》 SCIE 2024年第4期60-66,共7页
In order to solve the immaturity of decision-making methods in the regulation of winter heating in greenhouses,this study proposed a solution to the problem of greenhouse winter heating regulation using a dynamic prog... In order to solve the immaturity of decision-making methods in the regulation of winter heating in greenhouses,this study proposed a solution to the problem of greenhouse winter heating regulation using a dynamic programming algorithm.A mathematical model that included indoor environmental state variables,optimization decision variables,and outdoor random variables was established.The temperature is kept close to the expected value and the energy consumption is low.The model predicts the control solution by considering the cost function within the next 10 steps.The two-stage planning method was used to optimize the state of each moment step by step.The temperature control strategy model was obtained by training the relationship between indoor temperature,outdoor temperature,and heating time after optimization using a regression algorithm.Based on a typical Internet of Things(IoT)structure,the greenhouse control system was designed to regulate the optimal control according to the feedback of the current environment.Through testing and verification,the optimized control method could stabilize the temperature near the target value.Compared to the threshold control(threshold interval of 2.0°C)under similar weather conditions,the optimized control method reduced the temperature fluctuation range by 0.9°C and saved 7.83 kW·h of electricity,which is about 14.56%of the total experimental electricity consumption.This shows that the dynamic programming method is feasible for environmental regulation in actual greenhouse production,and further research can be expanded in terms of decision variables and policy models to achieve a more comprehensive,scientific,and precise regulation. 展开更多
关键词 GREENHOUSE dynamic programming heating control model predictive control Internet of Things
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Application of HEMS cooling technology in deep mine heat hazard control 被引量:46
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作者 HE Man-chao 《Mining Science and Technology》 EI CAS 2009年第3期269-275,共7页
This paper mainly deals with the present situation, characteristics, and countermeasures of cooling in deep mines.Given existing problems in coal mines, a HEMS cooling technology is proposed and has been successfully ... This paper mainly deals with the present situation, characteristics, and countermeasures of cooling in deep mines.Given existing problems in coal mines, a HEMS cooling technology is proposed and has been successfully applied in some mines.Because of long-term exploitation, shallow buried coal seams have become exhausted and most coal mines have had to exploit deep buried coal seams.With the increase in mining depth, the temperature of the surrounding rock also increases, resulting in ever increasing risks of heat hazard during mining operations.At present, coal mines in China can be divided into three groups, i.e., normal temperature mines, middle-to-high temperature mines and high temperature mines, based on our investigation into high temperature coal mines in four provinces and on in-situ studies of several typical mines.The principle of HEMS is to extract cold energy from mine water inrush.Based on the characteristics of strata temperature field and on differences in the amounts of mine water inrush in the Xuzhou mining area, we proposed three models for controlling heat hazard in deep mines:1) the Jiahe model with a moderate source of cold energy;2) the Sanhejian model with a shortage of source of cold energy and a geothermal anomaly and 3) the Zhangshuanglou model with plenty of source of cold energy.The cooling process of HEMS applied in deep coal mine are as follows:1) extract cold energy from mine water inrush to cool working faces;2) use the heat extracted by HEMS to supply heat to buildings and bath water to replace the use of a boiler, a useful energy saving and environmental protection measure.HEMS has been applied in the Jiahe and Sanhejian coal mines in Xuzhou, which enabled the temperature and humidity at the working faces to be well controlled. 展开更多
关键词 deep mine heat hazard mine classification mine water inrush heat hazard control model
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Design and control of methyl acetate-methanol separation via heat-integrated pressure-swing distillation 被引量:13
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作者 Zhishan Zhang Qingjun Zhang +2 位作者 Guijie Li Meiling Liu Jun Gao 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2016年第11期1584-1599,共16页
Design and control of pressure-swing distillation(PSD) with different heat integration modes for the separation of methyl acetate/methanol azeotrope are explored using Aspen Plus and Aspen Dynamics. First, an optimum ... Design and control of pressure-swing distillation(PSD) with different heat integration modes for the separation of methyl acetate/methanol azeotrope are explored using Aspen Plus and Aspen Dynamics. First, an optimum steady-state separation configuration conditions are obtained via taking the total annual cost(TAC) or total reboiler heat duty as the objective functions. The results show that about 27.68% and 25.40% saving in TAC can be achieved by the PSD with full and partial heat integration compared to PSD without heat integration. Second,temperature control tray locations are obtained according to the sensitivity criterion and singular value decomposition(SVD) analysis and the single-end control structure is effective based on the feed composition sensitivity analysis. Finally, the comparison of dynamic controllability is made among various control structures for PSD with partial and full heat integration. It is shown that both control structures of composition/temperature cascade and pressure-compensated temperature have a good dynamic response performance for PSD with heat integration facing feed flowrate and composition disturbances. However, PSD with full heat integration performs the poor controllability despite of a little bit of economy. 展开更多
关键词 Pressure-swing distillation Azeotrope Heat integration Dynamic control Methyl acetate/methanol
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Energy Efficient Thermal Comfort Control for Residential Building Based on Nonlinear EMPC
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作者 Xucheng Chang Bing Kong +3 位作者 Yong Li GaofengRen Chao Zhang ZhengheWang 《Energy Engineering》 EI 2022年第5期1941-1966,共26页
For purpose of achieving the desired thermal comfort level and reducing the economic cost of maintaining the thermal comfort of green residential building,an energy efficient thermal comfort control strategy based on ... For purpose of achieving the desired thermal comfort level and reducing the economic cost of maintaining the thermal comfort of green residential building,an energy efficient thermal comfort control strategy based on economic model predictive control(EMPC)for green residential buildings which adopts household heat metering is presented.Firstly,the nonlinear thermal comfort model of heating room is analyzed and obtained.A practical nonlinear thermal comfort prediction model is obtained by using an approximation method.Then,the economic cost function and optimization problem of energy-saving under the necessary thermal comfort requirements are constructed to realize the optimal economic performance of the dynamic process.The energy efficient thermal comfort MPC(EETCMPC)is designed.Finally,the comparison and analysis between EETCMPC and Double-layer Model Predictive Control(DMPC)is simulated.The simulation results reveal that when the clothing insulation is typical,the energy efficiency of EETCMPC is 8.9%and 11.6%,respectively,in the two simulation scenarios.When the clothing insulation varies with temperature,the energy efficiency of EETCMPC is 7.29%and 9.15%,respectively,and the total energy consumption is reduced by about 1.65%and 14.6%,respectively,compared with the typical clothing insulation.The economic performance is improved in the thermal comfort dynamic process of heating room. 展开更多
关键词 Household control and heat metering EMPC PMV(Predicted Mean Vote)thermal comfort energy efficient
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Principles and technology for stepwise utilization of resources for mitigating deep mine heat hazards 被引量:17
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作者 HE Manchao CAO Xiuling +4 位作者 XIE Qiao YANG Jiahua QI Ping YANG Qing CHEN Xueqian 《Mining Science and Technology》 EI CAS 2010年第1期20-27,共8页
As is well known, deep mines are hot. As mining depth increases, the temperature of the surrounding rock also increases. This seriously affects mine safety and production and has restricted the exploitation of deep co... As is well known, deep mines are hot. As mining depth increases, the temperature of the surrounding rock also increases. This seriously affects mine safety and production and has restricted the exploitation of deep coal resources. Therefore, reducing the working face temperature to improve working conditions by controlling these heat hazards is an urgent problem. Considering problems in cooling deep mines both domestically and abroad along with the actual conditions of the Zhangshuanglou coal mine, we propose a HEMS technology that uses heat resources from deep mines in a stepwise manner. HEMS means a high temperature ex-change machinery system. Mine inrush-water is used as a source of cooling. Twice the energy is extracted from the mine inrush water. Heat is used for building heating in the winter and cold water is used for cooling buildings in the summer. This opens a new technology for stepwise utilization of heat energy in deep mines. Energy conservation and reduced pollution, an improved environment and sustainable economic development are realized by this technique. The economic and social effects are obvious and illustrate a good prospect for the application and extension of the method. 展开更多
关键词 cooling system heat resources in deep mine heat hazard control mine water inrush stepwise utilization
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Single-Phase Forced Convection Heat Transfer in Micro Rectangular Channels 被引量:4
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作者 赵增会 余建祖 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2003年第1期7-11,共5页
Increase in the integration and package density of aviation electronic equipment provides severe challenge to heat control for electronic components, yet the microchannel radiator offers an efficient method for solvin... Increase in the integration and package density of aviation electronic equipment provides severe challenge to heat control for electronic components, yet the microchannel radiator offers an efficient method for solving the problem of cooling electronic chips and devices. In this paper, 6 micro rectangle channels with different sizes were designed and fabricated; the experiment of single\|phase forced convection heat transfer was conducted with solution of CH\-5OH, the most commonly used coolant for aviation electronic equipment, flowing through those microchannels. The influences of liquid velocity, degree of coolant supercooling, and configuration of microchannels on the heat transfer characteristics were analyzed respectively. 展开更多
关键词 MICROCHANNEL forced convection heat transfer heat control
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Visco-elastic-plastic model of deep underground rock affected by temperature and humidity 被引量:9
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作者 GAO, Yanan GAO, Feng +1 位作者 ZHANG, Zhizhen ZHANG, Tao 《Mining Science and Technology》 EI CAS 2010年第2期183-187,共5页
As the depth of exploitation increases,studies on constitutive models of rock affected by temperature and humidity become very important.Based on the Nishihara model,a visco-elastic-plastic rock model was established ... As the depth of exploitation increases,studies on constitutive models of rock affected by temperature and humidity become very important.Based on the Nishihara model,a visco-elastic-plastic rock model was established by using the coefficients of thermal and humidity expansion,thermal viscosity attenuation,humid viscosity attenuation and acceleration rheology components.We used the definition of a controlled heat circle to explain the model.The results show that the behavior of rock,affected by temperature and humidity,is stable as a function of time when the stress is lower than the first yield stress σS1;the creep rate will increase due to the effect of temperature and humidity when the stress is greater than or equal to σS1;the creep rate will accelerate at an increasing rate when the stress is greater than or equal to the second yield stress σS2,which results in a failure of the roadway.The model derived in this study can completely describe visco-elastic-plastic characteristics and reflects the three stages of rock creep. 展开更多
关键词 temperature humidity CREEP controlled heat circle
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Fabrication of high-quality three-dimensional photonic crystal heterostructures 被引量:3
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作者 刘正奇 冯天华 +2 位作者 戴峭峰 吴立军 兰胜 《Chinese Physics B》 SCIE EI CAS CSCD 2009年第6期2383-2388,共6页
Three-dimensional photonic crystal (PC) heterostructures with high quality are fabricated by using a pressure controlled isothermal heating vertical deposition technique. The formed heterostructures have higher qual... Three-dimensional photonic crystal (PC) heterostructures with high quality are fabricated by using a pressure controlled isothermal heating vertical deposition technique. The formed heterostructures have higher quality, such as deeper band gaps and sharper band edges, than the heterostructures reported so far. Such a significant improvement in quality is due to the introduction of a thin TiO2 buffer layer between the two constitutional PCs. It is revealed that the disorder caused by lattice mismatch is successfully removed if the buffer layer is used once. As a result, the formed heterostructures possess the main features in the band gap of constitutional PCs. The crucial role of the thin buffer layer is also verified by numerical simulations based on the finite-difference time-domain technique. 展开更多
关键词 photonic crystal heterostructure pressure controlled isothermal heating vertical deposition finite-difference time-domain technique
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A Dual-driven Intelligent Combination Control of Heat Pipe Space Cooling System 被引量:4
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作者 LI Yunze LI Mingmin LEE Kok Meng 《Chinese Journal of Aeronautics》 SCIE EI CAS CSCD 2012年第4期566-574,共9页
Effective thermal control systems are essential for reliable operation of spacecraft.A dual-driven intelligent combination control strategy is proposed to improve the temperate control and heat flux tracking effects.B... Effective thermal control systems are essential for reliable operation of spacecraft.A dual-driven intelligent combination control strategy is proposed to improve the temperate control and heat flux tracking effects.Both temperature regulation and heat flux tracking errors are employed to generate the final control action;their contributions are adaptively adjusted by a fuzzy fusing policy of control actions.To evaluate the control effects,describe a four-nodal mathematical model for analyzing the dynamic characteristics of the controlled heat pipe space cooling system(HP-SCS) consisting of an aluminum-ammonia heat pipe and a variable-emittance micro-electromechanical-system(MEMS) radiator.This dynamical model calculates the mass flow-rate and condensing pressure of the heat pipe working fluid directly from the systemic nodal temperatures,therefore,it is more suitable for control engineering applications.The closed-loop transient performances of four different control schemes have been numerically investigated.The results conclude that the proposed intelligent combination control scheme not only improves the thermal control effects but also benefits the safe operation of HP-SCS. 展开更多
关键词 heat pipe space cooling system dynamic modeling intelligent combination control micro-electromechanical-system
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Bionic Photovoltaic Panels Bio-Inspired by Green Leaves
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作者 MatthiasZhr Dennis Friedrich +2 位作者 Tania Y.Kloth Gerhard Goldmann Helmut Tributsch 《Journal of Bionic Engineering》 SCIE EI CSCD 2010年第3期284-293,共10页
In strong solar light, silicon solar panels can heat up by 70℃ and, thereby, loose approximately one third of their efficiencyfor electricity generation. Leaf structures of plants on the other hand, have developed a ... In strong solar light, silicon solar panels can heat up by 70℃ and, thereby, loose approximately one third of their efficiencyfor electricity generation. Leaf structures of plants on the other hand, have developed a series of technological adaptations,which allow them to limit their temperature to 40-45℃ in full sunlight, even if water evaporation is suppressed. This is accomplishedby several strategies such as limitation of leaf size, optimization of aerodynamics in wind, limitation of absorbedsolar energy only to the useful fraction of radiation and by efficient thermal emission. Optical and infrared thermographicmeasurements under a solar simulator and in a streaming channel were used to investigate the corresponding properties of leavesand to identify suitable bionic model systems. Experiments started with the serrated structure of ordinary green leaves distributedover typical twig structures and finally identified the Australian palm tree Licuala ramsayi as a more useful bionic model. Itcombines a large area for solar energy harvesting with optimized aerodynamic properties for cooling and is able to restructureitself as a protection against strong winds. The bionic models, which were constructed and built, are analyzed and discussed. 展开更多
关键词 BIONICS photovoltaic panel green leaves heat control Licuala ramsayi
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Null Controllability for Some Systems of Two Backward Stochastic Heat Equations with One Control Force
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作者 Hongheng LI Qi LÜ 《Chinese Annals of Mathematics,Series B》 SCIE CSCD 2012年第6期909-918,共10页
Abstract The authors establish the null controllability for some systems coupled by two backward stochastic heat equations. The desired controllability result is obtained by means of proving a suitable observability e... Abstract The authors establish the null controllability for some systems coupled by two backward stochastic heat equations. The desired controllability result is obtained by means of proving a suitable observability estimate for the dual system of the controlled system. 展开更多
关键词 Backward stochastic heat equation Null controllability Observabilityestimate
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Research on Input Power Testing Technology of Smart Toilet
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作者 Jiaqiang Zhong 《Journal of Electronic Research and Application》 2020年第4期25-29,共5页
Input power is an important indicator for the safety testing of electrical and electronic products.Smart toilets have been frequently detected that the actual input power is inconsistent with the nominal power.Researc... Input power is an important indicator for the safety testing of electrical and electronic products.Smart toilets have been frequently detected that the actual input power is inconsistent with the nominal power.Research and analysis show that the accuracy of the input power measurement results of the smart toilet mainly depends on the temperature control principle and power test method of the product.This article mainly discusses the characteristics of product temperature control,the testing method of mean and peak power and its characteristics,which will provide reference for the input power test of the smart toilet,and will improve the accuracy of power measurement. 展开更多
关键词 Input power Mean power Smart toilet PID instant heating control
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Interpreting the dynamic effect of internal heat integration on reactive distillation columns
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作者 Yang Yuan Liang Zhang +3 位作者 Haisheng Chen Shaofeng Wang Kejin Huang Huan Shao 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2017年第1期89-102,共14页
In this work,the impact of internal heat integration upon process dynamics and controllability by superposing reactive section onto stripping section,relocating feed locations,and redistributing catalyst within the re... In this work,the impact of internal heat integration upon process dynamics and controllability by superposing reactive section onto stripping section,relocating feed locations,and redistributing catalyst within the reactive section is explored based on a hypothetical ideal reactive distillation system containing an exothermic reaction:A + BC + D.Steady state operation analysis and closed-loop controllability evaluation are carried out by comparing the process designs with and without the consideration of internal heat integration.For superposing reactive section onto stripping section,favorable effect is aroused due to its low sensitivities to the changes in operating condition.For ascending the lower feed stage,somewhat detrimental effect occurs because of the accompanied adverse internal heat integration and strong sensitivity to the changes in operating condition.For descending the upper feed stage,serious detrimental effect happens because of the introduced adverse internal heat integration and strong sensitivity to the changes in operating condition.For redistributing catalyst in the reactive section,fairly small negative influence is aroused by the sensitivity to the changes in operating condition.When reinforcing internal heat integration with a combinatorial use of these three strategies,the decent of the upper feed stage should be avoided in process development.Although the conclusions are derived based on the hypothetical ideal reactive distillation column studied,they are considered to be of general significance to the design and operation of other reactive distillation columns. 展开更多
关键词 Reactive distillation column Internal heat integration Process design Process dynamics Process control
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Tailored heterostructured Ni_(3)N-NiO nano-frameworks for boosting electrocatalytic oxygen evolution via surface-modulated plasma strategy
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作者 Bo Ouyang Haonan Qin +5 位作者 Chao Sun Yilin Deng Ang Li Jipeng Zhu Erjun Kan Rajdeep Singh Rawat 《Nano Research》 SCIE EI CSCD 2024年第9期7909-7917,共9页
The facile reconfiguration of phases plays a pivotal role in enhancing the electrocatalytic production of H2 through heterostructure formation.While chemical methods have been explored extensively for this purpose,pla... The facile reconfiguration of phases plays a pivotal role in enhancing the electrocatalytic production of H2 through heterostructure formation.While chemical methods have been explored extensively for this purpose,plasma-based techniques offer a promising avenue for achieving heterostructured nano-frameworks.However,the conventional plasma approach introduces complexities,leading to a multi-step fabrication process and challenges in precisely controlling partial surface structure modulation due to the intricate interaction environment.In our pursuit of heterostructures with optimized oxygen evolution reaction(OER)behavior,we have designed a facile auxiliary insulator-confined plasma system to directly attain a Ni_(3)N-NiO heterostructure(hNiNO).By meticulously controlling the surface heating process during plasma processing,such approach allows for the streamlined fabrication of hNiNO nano-frameworks.The resulting nano-framework exhibits outstanding catalytic performance,as evidenced by its overpotential of 320 mV at a current density of 10 mA·cm^(-2),in an alkaline environment.This stands in stark contrast to the performance of NiO-covered Ni_(3)N fabricated using the conventional plasma method(sNiNO).Operando plasma diagnostics,coupled with numerical simulations,further substantiates the influence of surface heating due to auxiliary insulator confinement of the substrate on typical plasma parameters and the formation of the Ni_(3)N-NiO nanostructure,highlighting the pivotal role of controlled surface temperature in creating a high-performance heterostructured electrocatalyst. 展开更多
关键词 structural modulation auxiliary insulator-confined plasma surface heating control HETEROSTRUCTURE electrocatalytic O_(2) evolution
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Curative effect of heat-sensitive moxibustion on chronic persistent asthma: a multicenter randomized controlled trial 被引量:20
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作者 Rixin Chen Mingren Chen +13 位作者 Jun Xiong Zhenhai Chi B0 Zhang Ning Tian Zhenhua Xu Tangfa Zhang Wanyao Li Wei Zhang Xiaofeng Rong Zhen Wang Gang Sun Baohe Ge Guoxiong Yu Nanchang Song 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2013年第5期584-591,共8页
OBJECTIVE:To compare the curative effects of heat-sensitive moxibustion with conventional drugs on chronic persistent asthma and seek a valuable therapy to replaceWestern Medicine.METHODS:The participants in this mult... OBJECTIVE:To compare the curative effects of heat-sensitive moxibustion with conventional drugs on chronic persistent asthma and seek a valuable therapy to replaceWestern Medicine.METHODS:The participants in this multi-center,randomized,and controlled study were randomly divided into two groups:group A(n=144),treated with heat-sensitive moxibustion(50 sessions)and group B(n=144),treated with Seretide(salmeterol50μg/fluticasone 250μg,twice a day).The scores of asthma control test(ACT),forced expiratory volume in 1 second(FEV1),peak expiratory flow(PEF),and attack frequency were measured after 15,30,60,and 90 days of treatment.Patients followed up3 and 6 months after treatment.RESULTS:There was a significant difference(P=0.0002)in the ACT score and lung function between the two groups after 3 months of treatment and(P=0.000 03)during the follow-up visits.In addition,heat-sensitive moxibustion reduced attack frequency in the period from inclusion to the6-month follow-up visit.CONCLUSION:This study shows that heat-sensitive moxibustion may have a comparable curative effect toSeretide(salmeterol/fluticasone)on asthma. 展开更多
关键词 Moxibustion Asthma Randomized controlled trial Heat sensitive Seretide
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Jinye Baidu granule for wind-warmth lung-heat disease(heat in the lung-wei): protocol for a randomized, double-blind, parallel, controlled trial
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作者 Jiang Junjie Zhang Yin +6 位作者 Xie Yanming Li Yuan Sun Shuailing Zhang Yili Wang Shuo Zhu Yong Qi Wensheng 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2017年第5期621-628,共8页
OBJECTIVE: To observe the curative effect of Jinye Baidu granule in the treatment of fever and swollen and sore throat caused by wind-warmth lung-heat disease(heat in the lung-wei) to further identify the indications.... OBJECTIVE: To observe the curative effect of Jinye Baidu granule in the treatment of fever and swollen and sore throat caused by wind-warmth lung-heat disease(heat in the lung-wei) to further identify the indications.METHODS: This randomized, double-blind, parallel, controlled trial will include patients with acute upper respiratory infection and wind-warmth lung-heat disease(heat in the lung-wei). Patientswith serious bacterial infection(white blood cell count > 12 × 10~9, neutrophils > 80%) will be excluded. Patients will be divided into three categories(blocks) according to their condition: fever only, a swollen and sore throat, and combined fever plus a swollen and sore throat. Patients within each of the three blocks will be further divided into a treatment group and a control group via stratified blocked randomization. The treatment group will be treated with Jinye Baidu granule, and the control group will be treated with Fufang Shuanghua granule. The primary outcome measure will be body temperature recovery time for patients with fever, throat symptom score for patients with a swollen and sore throat, and body temperature recovery time and throat symptom score for patients with combined fever plus a swollen and sore throat. Routine blood testing, urine testing, liver function, kidney function and ECG data of all patients will be collected as safety indices before and after enrollment, and adverse events will be recorded during the whole trial course.CONCLUSION: This study protocol will include stratified block analysis according to patients' symptoms, and identify the accurate clinical indications of Jinye Baidu granule. It will also enable safety evaluation from laboratory indices and adverse events, which will provide reliable evidence for clinical treatment. 展开更多
关键词 Syndrome of wind heat invading lung and stomach Respiratory tract infections Randomized controlled trial Clinical protocols Jinye Baidu granule
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